Troglitazone and Δ2Troglitazone Enhance Adiponectin Expression in Monocytes/Macrophages through the AMP-Activated Protein Kinase Pathway by Jaw-Shiun Tsai, Lee-Ming Chuang, Ching-Shih Chen, Chan-Jung Liang, Yuh-Lien Chen, Ching-Yu Chen

“…TG and Δ2TG enhanced adiponectin mRNA and protein expression in THP-1 cells by quantitative real-time PCR, Western blot, and immunocytochemistry. …”
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Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity by Liliana Dell’Osso, Giulia Amatori, Chiara Bonelli, Benedetta Nardi, Enrico Massimetti, Ivan Mirko Cremone, Stefano Pini, Barbara Carpita

“…In the analysis of PAS-SV scores, the ASD group once again achieved the highest scores after the PD individuals, although this time the difference was not statistically significant compared to the other diagnostic groups. …”
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From physical activity patterns to cognitive status: development and validation of novel digital biomarkers for cognitive assessment in older adults by Ling-Jie Fan, Feng-Yi Wang, Jun-Han Zhao, Jun-Jie Zhang, Yang-An Li, Jia Tang, Tao Lin, Quan Wei

“…Conclusions This study identifies novel time-frequency domain features of physical activity that show robust associations with cognitive status across two independent cohorts. …”
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Priming and task‐specific training for arm weakness post stroke: A randomized controlled trial by Erin C. King, Jacob M. Schauer, Shyam Prabhakaran, Alexandra Wax, Sebastian Urday, Sangeetha Madhavan, Daniel M. Corcos, Mary Ellen Stoykov

“…The magnitude of change seen in both groups reflects the largest improvement achieved with just 22.5 h of TST in this population, matching or out‐performing more invasive, time‐intensive, and costly interventions proposed in recent years.…”
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Evaluation of Comparative Efficacy of Ashwagandha (Withania somnifera) vs Brahmi (Bacopa monnieri Linn) on Stress Level and Quality of Sleep in the Subjects Experiencing Mental Str... by Mohnish Vijay Gokhale, Vaishali Kuchewar, Pankaj Yadav, Bhishmani Tarare

“…Group-A (Experimental Group) and Group-B (Control Group) will be given Brahmi ghana (extract of Bacopa monnieri Linn) and Ashwagandha ghana (extract of Withania somnifera), respectively with Luke warm water at bed time for 60 days. The patients will be assessed on every 15th day through Perceived Stress Scale (PSS) and Pittsburgh Sleep Quality Index (PSQI) scales.…”
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Burden of coronary artery calcification in ANCA-associated vasculitis by Claire Cook, Brittany Weber, Catherine Ahola, Zachary S. Wallace, Michael Hendrickson, Anushri Parakh, Sandeep Hedgire, Michael Lu

“…Of 116 (66%) patients with non-zero CAC scores, only 29 (25%) were on a statin. In a time-to-event analysis, CAC of 100 or higher trended towards association with higher risk of major adverse cardiovascular events (χ2=1.9, p=0.16).Conclusion A majority of patients with AAV had clinically significant CAC. …”
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An optimized deep-forest algorithm using a modified differential evolution optimization algorithm: A case of host-pathogen protein-protein interaction prediction by Jerry Emmanuel, Itunuoluwa Isewon, Jelili Oyelade

“…However, deep forest-based models have limitations such as manual hyperparameter optimization and time and memory usage inefficiencies. Bayesian optimization is a widely used model-based hyperparameter optimization method. …”
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Evaluation of patient comfort and satisfaction after the surgical removal of mandibular impacted molars using a piezo-electric technique: A randomized double-blind clinical trial by Khalid Zabin Alotaibi, Waleed Mohammed Al Rasheed, Jiingade Krishnojirao Dayashankara Rao, Abdulrahman Altwaijri, Gharam Mefleh Alharbi, Shatha saleh Aljaber

“…The level of significance was set at p < 0.05. The surgery time taken was more in the Piezo group (26.96 ± 12.201) in comparison with the Rotary group (21.32 ± 12.786- (p = 0.011∗). …”
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Amyopathic dermatomyositis with a rapidly progressing interstitial pneumonia by Darija Logvinova, Dace Žentiņa, Kristīne Ivanova, Inita Buliņa, Zaiga Kravale

“…A multidisciplinary approach, with collaboration between specialized centres, is crucial for early diagnosis and timely initiation of treatment.…”
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Cohort profile: Health in Central Denmark (HICD) cohort - a register-based questionnaire survey on diabetes and related complications in the Central Denmark Region by Annelli Sandbæk, Else-Marie Dalsgaard, Kasper Norman, Lasse Bjerg, Anders Aasted Isaksen

“…A 90-item questionnaire was distributed to eligible members of this cohort on 18 November 2020 (estimated time required for completion: 15–20 min).Findings to date We invited 90 854 persons to take part in the survey, of whom 51 854 answered the questionnaire (57.1%). …”
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River Channel Microgeomorphic Feature Extraction and Potential Sandstorm Source Identification Method Based on a Convolutional Autoencoder Model by Kecong Wu, Lirong Chen, Yalige Bai, Xinhang Wang, Danzeng Pingcuo, Zhongpeng Han, Chengshan Wang

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The Role of Higher Education Through the Eyes of Hungarian Undergraduate Students and Graduates: A Qualitative Exploratory Study by Zsófia Kocsis, Gabriella Pusztai

“…The selection criterion for participants (n=18) was that they had obtained their diploma within the last three years, while, for the other portion of the interviewees, a selection criterion was that they were full-time students. The participants are students of the same rural higher education institution. …”
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Grain yield, cooking quality, and aroma of fragrant rice as affected by nitrogen source and method of application by Rajesh Chakraborty, Tuhin Suvra Roy, Jun-Ichi Sakagami

“…The combined application of N as a foliar dose and soil application, along with ammonium nitrate and ammonium sulfate, showed improved results for various parameters such as gelatinization temperature, gel consistency, protein content, cooking time, imbibition ratio, 2-AP content, grain aroma, and taste of BRRI dhan70 compared to 100% soil application of N. …”
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Improvement in the Flux Uniformity of the Solar Dish Concentrator System through a Concave Quartz Window by Du-zhong Nie, You-duo Peng, Jian Yan, Cheng-ji Mi, Yong-xiang Liu, Yong Tian

“…Based on the Monte Carlo ray-tracing method, the results showed that the nonuniformity coefficient of the receiver was 0.68 and the peak concentration ratio was 1320.21 by using a plane quartz window. At the same time, when the receiver is in the best optical performance, it is the receiver with sinusoidal, conical, spherical, and hyperbolic tangent quartz windows, respectively. …”
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GENOME POLITICS: STRATEGY AND TACTICS by Jonas Rubikas

“…Human beings as all living Nature obey the bible trinity law: we are not only parents but also offsprins at the same time, we are joined to each other by the eternal renovation power - the GENOME. …”
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Enhanced ensemble learning-based uncertainty and sensitivity analysis of ventilation rate in a novel radiative cooling building by Majid Mohsenpour, Mohsen Salimi, Atieh Kermani, Majid Amidpour

“…The model's performance is improved across key metrics such as R2, RMSE, and MAE. For the first time, uncertainty and sensitivity analysis is applied to assess the impact of indoor and outdoor conditions on ventilation rates. …”
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Mapping the evidence on interventions that mitigate the health, educational, social and economic impacts of child marriage and address the needs of child brides: a systematic scopi... by Shatha Elnakib, Ahmed K. Ali, Kate Mieth, Venkatraman Chandra-Mouli

“…We also note the paucity of media-based interventions, despite their popularity among adolescents. Over time, interventions addressing the needs of child brides have increased, but the preponderance of evidence has focused on SRH interventions, with interventions that couple education with adolescent-friendly health services demonstrating promise. …”
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Combination therapy of intravitreal ranibizumab and sub-tenon triamcinolone for treatment of resistant diabetic macular edema: a clinical study in Egypt by Hossam Eldin M. A. Khalil, Hazem E. Haroun, Alaa A. I. Shalan, Waleed M. Mahran

“…However, this elevation is usually just transitory lasting for short periods of time and is within the safe, insignificant rise ranges. …”
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Combined anti-leukemic effect of gilteritinib and GSK-J4 in FLT3-ITD+ acute myeloid leukemia by Qi Zhou, Yongyu Guan, Pingping Zhao, Huiyuan Chu, Yaming Xi

“…Gilteritinib mainly induces cell cycle phase arrest at the S or G0/G1, and GSK-J4 inhibits the cell cycle progression in the S phase and reduces cell viability by reducing the expression of key regulatory factors from the G1 phase to the S phase. At the same time, GSK-J4 enhances the expression of apoptosis-related proteins (Bax and cleavage caspase-9). …”
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Viral conjunctivitis in children: the specific clinical features and treatment by N.V. Kazinskaya, V.Yu. Evgraphov, I.A. Il’inskaya

“…In addition, a clinical case report is presented where an incorrect interpretation of symptoms of the anterior eye segment inflammation has led to the inappropriate medication administration and the development of such complications as keratitis and reduced visual acuity. In general, timely diagnosis of the disease and adequate treatment of pediatric patients, in contrast to adults, ensures an uncomplicated clinical outcome, without scarring, uveitis or residual infiltrates. …”
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