Evaluating the Effect on Total Daily Insulin Dose in Adult Patients with Type 1 Diabetes Managed with Metformin and/or GLP-1 or GLP-1/GIP Receptor Agonists by Mayeesha Ahmed, Emily Pierson, Molly Webster

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Comparison of Adhesion of Soft-Liner between Conventional PMMA and 3D Printed Resin Denture Bases by Dawood Jadaan, Juzailah Roffie, Husniyati Roslan, Nahas P

“…The third group consisted of 12 samples that were packed at the dough stage of acrylic and soft liner at the same time. After that, the samples from the first and second groups were split in two, with one half receiving no surface treatment and the other half undergoing sandblasting. …”
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An Overview of Dentist–Patient Communication in Quality Dental Care by Jasmine Cheuk Ying Ho, Hollis Haotian Chai, Bella Weijia Luo, Edward Chin Man Lo, Michelle Zeping Huang, Chun Hung Chu

“…Nonetheless, it has been widely acknowledged that dentists universally encounter the repercussions arising from suboptimal communication strategies. Time constraints, difficulties in establishing rapport, the oral-health illiteracy of the patients, the poor communication skills of the dentists, dentists’ perceptions, and language barriers often hinder dentist–patient communication. …”
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Sustainable pectin extraction from Riang husk using ultrasound-assisted extraction with deep eutectic solvents and its potential in antipollution products by Manee Saelee, Hla Myo, Nuntawat Khat-udomkiri

“…The condition that exhibited the highest yield were found to be a liquid-to-solid ratio of 40 mL/g, 35 % amplitude (ultrasonic power of 28.11 W), and 60 min of extraction time. The extracted pectin was primarily composed of monosaccharides, including galacturonic acid (53.74 %), arabinose (23.97 %), galactose (12.36 %), and rhamnose (6.81 %). …”
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Cost-Effectiveness of Apomorphine Sublingual Film as an “On-Demand” Treatment for “OFF” Episodes in Patients with Parkinson's Disease by Andrew Thach, Noam Kirson, Miriam L. Zichlin, Ibrahima Dieye, Eric Pappert, G. Rhys Williams

“…Total and incremental patient costs (in 2020 US dollars), total time spent without “OFF” episode symptoms, and quality-adjusted life years (QALY) gained were summarized and compared. …”
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‘I haven’t met them, I don’t have any trust in them. It just feels like a big unknown’: a qualitative study exploring the determinants of consent to use Human Fertilisation and Emb... by Claire Carson, Lisa Hinton, Jenny Kurinczuk, Maria Quigley

“…Verbatim transcripts were analysed using the ‘one sheet of paper’ method to identify themes.Setting Women and men were recruited between September 2015 and December 2017, via fertility clinics across England and online advertising, then interviewed at a location convenient to them.Participants 20 patients and 9 staff were interviewed, 40 patients completed the online survey.Results Consent for disclosure (CD) forms are completed at a stressful time, when patients often feel overwhelmed; these forms were considered a low priority. …”
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An in-situ study in the Xijiang River basin revealed adverse effects of total dissolved gas supersaturation on fish by Xuefeng Chen, Zhiguang Zhang, Yunong Qin, Shikang Liu, Yuanming Wang, Jingjie Feng, Kefeng Li

“…The bubble trauma scores of the experimental fish in TDG supersaturated water significantly increased with exposure time and significantly decreased after recovery in freshwater. …”
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Role of the Btk-PLCγ2 Signaling Pathway in the Bone Destruction of Apical Periodontitis by Lina Wang, Hong Zhang, Ming Dong, Meina Zuo, Shuo Liu, Ying Lu, Weidong Niu

“…By silencing Btk, the expression of Btk, PLCγ2, and NFATc-1 was detected by real-time qPCR and Western blot, and osteoclastogenesis was detected by enzyme histochemical staining to further confirm the role of Btk in bone resorption. …”
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Comparison and Impact Factor Analysis of Ground PM2.5 Retrieved by Aqua and Himawari-8 Satellite Products in Guangdong, China by Tingyuan Li, Xuejiao Deng, Jingyang Chen, Jie Xu, Jin Shen

“…Previous studies on PM2.5 concentrations in Guangdong have used the aerosol optical depth (AOD) determined by MODIS sensors on the Terra and Aqua satellites, which both have a transit time of once per day. In this study, based on AOD data obtained from the Aqua and Himawari-8 (H8) satellites and ground-based measurements, ground PM2.5 concentrations were compared using radiation theory and a semi-empirical model. …”
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An Actor-Oriented and Architecture-Driven Approach for Spatially Explicit Agent-Based Modeling by Eric Fotsing, Severin Vianey Tuekam Kakeu, Eric Desire Kameni, Marcellin Julius Antonio Nkenlifack

“…The development and maintenance of resulting models become cumbersome and time-consuming. In this article, we propose an actor and architecture-driven approach that relies on relevant existing methods and satisfies the needs of spatially explicit agent-based modeling and implementation. …”
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Effectiveness of supracondylar dome osteotomy in reducing lateral condylar prominence and enhancing functional outcomes in pediatric cubitus varus: a retrospective study by Yam Prakash Gurung, Sabin Pokharel, Rajan Bhusal, Tarun Rajbhandari, Ashok Kumar Banskota, Bibek Banskota

“…Results The mean age at surgery was 11.77 years (± 3.76), with an average time since injury of 54.15 months (± 31.76). Post-operatively, the radiological carrying angle improved from 23.90° (± 8.84) varus to 5.14° (± 7.64) valgus. …”
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Mean field limits of co-evolutionary signed heterogeneous networks by Marios Antonios Gkogkas, Christian Kuehn, Chuang Xu

“…In comparison to the recently emerging works on MFLs of IPS coupled on non-co-evolutionary networks (i.e., static networks or time-dependent networks independent of the dynamics of the IPS), our work seems the first to rigorously address the MFL of a co-evolutionary network model. …”
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Hypertension and retinal microvascular dysfunction (HyperVasc): protocol of a randomised controlled exercise trial in patients with hypertension by Justin Carrard, Lukas Streese, Timo Hinrichs, Henner Hanssen, Arno Schmidt-Trucksäss, Konstantin Gugleta, Joséphine Gander, Christoph Hauser

“…Vascular biomarkers are essential to timely diagnose this end-organ damage to improve cardiovascular (CV) risk stratification and medical decision making. …”
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Enhanced Drug Skin Permeation by Azone-Mimicking Ionic Liquids: Effects of Fatty Acids Forming Ionic Liquids by Takeshi Oshizaka, Shunsuke Kodera, Rika Kawakubo, Issei Takeuchi, Kenji Mori, Kenji Sugibayashi

“…<b>Background/Objectives</b>: Laurocapram (Azone) attracted attention 40 years ago as a compound with the highest skin-penetration-enhancing effect at that time; however, its development was shelved due to strong skin irritation. …”
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Climatic Background and Prediction of Boreal Winter PM2.5 Concentrations in Hubei Province, China by Yuanyue Huang, Zijun Tang, Zhengxuan Yuan, Qianqian Zhang

“…Conversely, the South Atlantic–Southwest Indian Ocean SST mode (SAIO) and the Ross Sea sea-ice mode (ROSIC) contribute to more stable local atmospheric conditions, which reduce pollutant dispersion and increase PM2.5 accumulation, thus exhibiting a positive correlation with DJF-HBPMC. (3) A multiple linear regression (MLR) model, using selected seasonal SST and SIC indices, effectively predicts DJF-HBPMC, showing high correlation coefficients (CORR) and anomaly sign consistency rates (AS) compared to real-time values. (4) In daily HBPMC forecasting, both the Reversed Unrestricted Mixed-Frequency Data Sampling (RU-MIDAS) and Reversed Restricted-MIDAS (RR-MIDAS) models exhibit superior skill using only monthly precipitation, and the RR-MIDAS offers the best balance in prediction accuracy and trend consistency when incorporating monthly precipitation along with monthly SST and SIC indices.…”
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Clinical Observation of Posterior-Chamber Phakic Implantable Collamer Lens V4c Implantation in Myopic Patients with Shallow Anterior Chamber Depth: A Retrospective, Consecutive Obs... by Juan Yuan, Shuang Wu, Zongli Hu, Chunlin Chen, Shiyang Ye, Jian Ye

“…In patients with myopia with shallow ACD (2.55-2.79 mm), a preoperative TIA >25.8° is safe and effective for a relatively long time after surgery; however, an extended long-term close follow-up is needed.…”
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Dual-hybrid intrusion detection system to detect False Data Injection in smart grids. by Saad Hammood Mohammed, Mandeep S Jit Singh, Abdulmajeed Al-Jumaily, Mohammad Tariqul Islam, Md Shabiul Islam, Abdulmajeed M Alenezi, Mohamed S Soliman

“…Future research should focus on integrating real-world smart grid data for validation, developing adaptive learning mechanisms, exploring other bio-inspired optimization algorithms, and addressing real-time processing and scalability challenges in large-scale deployments.…”
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Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center by Xin Wang, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Ming-hui Zhao

“…Regarding follow-up, patients received bortezomib-based or R-CHOP chemotherapy or supportive treatment only. The mean follow-up time was 22 ± 16 months, and the mean eGFR was 63.098 ± 27.439 ml/min/1.73 m2 at the end of follow-up. …”
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Statistical Evaluation and Trend Analysis of ANN Based Satellite Products (PERSIANN) for the Kelani River Basin, Sri Lanka by Helani Perera, Miyuru B. Gunathilake, Ravindu Panditharathne, Najib Al-mahbashi, Upaka Rathnayake

“…Satellite-based precipitation products, (SbPPs) have piqued the interest of a number of researchers as a reliable replacement for observed rainfall data which often have limited time spans and missing days. The SbPPs possess certain uncertainties, thus, they cannot be directly used without comparing against observed rainfall data prior to use. …”
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Development of a deep learning method to identify acute ischaemic stroke lesions on brain CT by Emanuele Trucco, Joanna M Wardlaw, Wenwen Li, Grant Mair, Amos Storkey, Alessandro Fontanella, Antreas Antoniou, Eleanor Platt, Paul Armitage

“…We explored the impact of ischaemic lesion features, background brain appearances and timing of CT (baseline or 24–48 hour follow-up) on DL performance.Results From 5772 CT scans of 2347 patients (median age 82), 54% had visible ischaemic lesions according to experts. …”
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