Benefit from regular versus leakage-related exchange of voice prostheses in patients post-laryngectomy considering complication rates and patient satisfaction feedback—a randomized... by Michał Żurek, Małgorzata Czesak, Daniel Majszyk, Anna Rzepakowska

“…Comparative analysis of REA and LEA revealed a significantly longer time between replacements in the LEA group (p = 0.023) and a significantly lower rate of complications in the REA group (p = 0.029). …”
Get full text

Performance Evaluation of Bone Glue-Modified Asphalt by Asif Ali, Naveed Ahmad, Muhammad Adeel, Syed Bilal Ahmed Zaidi, Muhammad Sohail Jameel, Farsan Ali Qureshi, Waqas Haroon, Syeda Aamara Asif

“…In Pakistan, temperature remains high for most of the time of the year; hence, asphalt binders with less susceptibility to higher temperatures are preferred for flexible pavements. …”
Get full text

LIM-kinase 1 effects on memory abilities and male courtship song in Drosophila depend on the neuronal type by A. V. Zhuravlev, E. S. Zalomaeva, E. S. Egozova, A. D. Emelin, V. V. Sokurova, E. A. Nikitina, E. V. Savvateeva-Popova

“…In the Drosophila brain, LIMK1 and p-cofilin levels appeared to be low in specific neuropil structures, including the mushroom body (MB) lobes and the central complex. At the same time, LIMK1 was observed in cell bodies, such as DAN clusters regulating memory formation in CCSP. …”
Get full text

Reconstructing Iraq after the Victory over the Islamic State: Prospects for International Engagement by article Editorial

“…The conclusion is drawn that smaller than expected commitments made by international donors in Kuwait (mostly in the form of loans and export credits) can be expalined, mainly, by the shift in the perceptions of the ‘established’ donors, and the U.S. in particular, which proved to be unwillling to invest large sums of money in a notoriously corrupt country and at the same time quite confident about the oil-rich Iraq’s ability to meet reconstruction needs from its own funds. …”
Get full text

Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus by A. A. Chesnokova, E. V. Ivanova, V. V. Pronin, O. A. Chupina, V. Yu. Fomenko, M. S. Volkov, V. N. Irza

“…This infection is included in the list of notifiable diseases of the World Organization for Animal Health, restrictive measures are established and the regionalization of the country’s territory is carried out in case of its occurrence. Timely vaccination of parent flocks in order to obtain immune offspring takes a priority place in the system of anti-epidemic measures. …”
Get full text

Tracheal Resection for Critical Airway Obstruction in Morquio A Syndrome by Claire Frauenfelder, Elizabeth Maughan, Johnny Kenth, Reema Nandi, Simon Jones, Robert Walker, Bill Walsh, Nagarajan Muthialu, Iain Bruce, Richard Hewitt, Colin Butler

“…Further work is needed to better understand the role and optimal timing of tracheal resection within this patient cohort so as to individually balance considerable surgical and anaesthetic risks against the potential symptomatic and life expectancy benefits.…”
Get full text

Ecological Water Demand Calculation with the Consideration of the Health of Fish Spawning Ground——A Case Study of Dongta Spawning Ground in Xijiang River by ZHOU Huabin, YU Chunxue, SU Meirong

“…Taking theDongta spawning ground in the Xijiang River Basin as the study area and four major Chinese carpsas the target species for the first time, this paper constructs the related suitability curve forthe hydrodynamic characteristic index, simulates the effects of factors such as flow velocity andwater depth on fish spawning grounds at different flow conditions by a two-dimensional riverhydrodynamic model, River2D, establishes the relationship between the flow conditions and weightedusable area (WUA) of four major Chinese carps habitats to determine the ecological water demand inthe study area. …”
Get full text

Socio-economic analysis of ovine livestock farms supported by the young farmer project within the scope of rural development by Muharrem Satar, Engin Sakarya

“…<p> <b>Materials and Methods: </b>The materials of the study were composed of data obtained from businesses of small ruminant enterprises first time starting in 2016 thanks to the young farmers project, with a simple random sampling method in Turkey's seven geographical regions selected from 121 enterprises rom provided with face to face interviews. …”
Get full text

DeepGlioSeg: advanced glioma MRI data segmentation with integrated local-global representation architecture by Ruipeng Li, Yuehui Liao, Yueqi Huang, Xiaofei Ma, Guohua Zhao, Yanbin Wang, Chen Song

“…Second, the model computes a region-based probability by comparing the number of pixels in tumor and background regions and assigns greater weight to regions with lower probabilities, thereby focusing on the tumor segment. Test-time augmentation (TTA) and volume-constrained (VC) post-processing are subsequently applied to refine the final segmentation outputs.ResultsExtensive experiments were conducted on three publicly available glioma MRI datasets and one privately owned clinical dataset. …”
Get full text

The philosophical foundations of digital twinning by David J Wagg, Christopher Burr, Jason Shepherd, Zack Xuereb Conti, Mark Enzer, Steven Niederer

“…Digital twins are a new paradigm for our time, offering the possibility of interconnected virtual representations of the real world. …”
Get full text

Effect of Walking Speeds on Complexity of Plantar Pressure Patterns by Ben-Yi Liau, Fu-Lien Wu, Yameng Li, Chi-Wen Lung, Ayman A. Mohamed, Yih-Kuen Jan

“…Complexity index (CI), a summation of MSE2D from all time scales, was used to quantify the changes of complexity of plantar pressure images. …”
Get full text

Undernutrition and Associated Factors among Lactating Women: Community-Based Cross-Sectional Study in Moyale District, Borena Zone, Southern Ethiopia by Hailu Bekele, Gebi Husein Jima, Ashenafi Habtamu Regesu

“…Finally, we recommend that governmental and nongovernmental organizations should organize timely interventions targeting lactating women.…”
Get full text

An open-label study to determine the maximum tolerated dose of oral ESK-440 administered as a single agent in patients with advanced or metastatic solid tumors by Russell J. Schilder, Drew Rasco, Manish R. Sharma

Get full text

P-glycoprotein and/or Histone Deacetylase 2 Regulates Steroid Responsiveness in Childhood Nephrotic Syndrome by Harshit Singh, Narayan Prasad, Durga Prasanna Misra, Akhilesh Kumar Jaiswal, Vikas Agarwal

“…Materials and Methods: Thirty-one patients were recruited at baseline (n = 31) (before initiating steroid therapy); after 6 weeks of steroid therapy, 24 patients achieved remission (steroid-sensitive NS [SSNS] n = 24 mean age, 7.96 ± 3.90), whereas seven patients were resistant to steroids (SRNS, n = 7, mean age 10.00 ± 3.55). mRNA expression of HDAC2 and P-gp and functional analysis of P-gp and enzymatic activity of HDAC2 were analyzed at baseline, and at 6 weeks of steroid treatment and at the time of relapse. Results: The expression of P-gp mRNA was significantly lower in individuals (n = 24) who achieved remission at 6-week steroid therapy as compared to baseline and those who were resistant (n = 7) to steroids (P < 0.005). …”
Get full text

Global burden of colorectal cancer: epidemiology, risk factors by E. A. Medvedeva, G. G. Maryin, A. A. Leshchenko, M. V. Chernogorova, M. B. Dolgova, D. A. Nazarov, S. A. Ivanov

“…Most colon tumors develop as a result of a multistep process involving a number of histological, morphological and genetic changes, the frequency of detection of which increases with the age of the patient. Timely screening aimed at identifying and removing precancerous neoplasms in the early stages can lead to a significant reduction in the incidence of CRC. …”
Get full text

Social media use is associated with body image concern in young adults during the COVID-19 pandemic by Marina de Sá Azevedo, Brenda Esper-Pereira, Larissa Vaz-Gonçalves, Raquel Machado Schincaglia, Marília Mendonça Guimarães, Karine Anusca Martins, Luciana Bronzi de Souza

“…Methods: Cross-sectional study conducted with 461 young adults (18-30yrs), from Midwest Brazil, who answered an online and self-reported questionnaire to determine the social media use, with questions about time of service, frequency of access, and media influence on behaviors. …”
Get full text

Uncovering the Risks: Investigating the Impact of Abnormal 50 g Results of Two-Step Gestational Diabetes Mellitus Screening in Pregnant Women by Sakine Rahımlı Ocakoglu, Bayram Ali Dorum, Zeliha Atak, Özlem Özgün Uyanıklar, Gökhan Ocakoğlu

“… Background/Aims: Gestational Diabetes Mellitus (GDM) is a prevalent medical concern among pregnant women. Timely identification and management of GDM can mitigate the potential for maternal and fetal complications. …”
Get full text

LTA4H rs2660845 association with montelukast response in early and late-onset asthma. by Cyrielle Maroteau, Antonio Espuela-Ortiz, Esther Herrera-Luis, Sundararajan Srinivasan, Fiona Carr, Roger Tavendale, Karen Wilson, Natalia Hernandez-Pacheco, James D Chalmers, Steve Turner, Somnath Mukhopadhyay, Anke-Hilse Maitland-van der Zee, Esteban G Burchard, Maria Pino-Yanes, Simon Young, Glenda Lassi, Adam Platt, Colin N A Palmer, PiCA Consortium

“…Our study demonstrates that genetic variation in LTA4H, together with timing of asthma onset, may contribute to variability in montelukast response. …”
Get full text

Development of Hollow Fiber Membranes Suitable for Outside-In Filtration of Human Blood Plasma by David Ramada, Bente Adema, Mohamed Labib, Odyl ter Beek, Dimitrios Stamatialis

“…They offer potential for more efficient long-term HD by reducing clogging and systemic anticoagulation needs and enhancing treatment time and toxin clearance.…”
Get full text

Association of AGTR1 A1166C and CYP2C9∗3 Gene Polymorphisms with the Antihypertensive Effect of Valsartan by Yi Liu, Xiaomu Kong, Yongwei Jiang, Meimei Zhao, Peng Gao, Xiao Cong, Yongtong Cao, Liang Ma

“…Based on the systolic blood pressure (SBP) and diastolic blood pressure (DBP) at the time of visit, the patients were divided into well-controlled group (n = 144, SBP/DBP <140/90 mmHg) and poorly controlled group (n = 137, SBP/DBP ≥140/90 mmHg). …”
Get full text