Showing 56,481 - 56,500 results of 63,767 for search '"The Times"', query time: 0.33s Refine Results
  1. 56481

    A Comparative Study of the In Vitro Intestinal Permeability of Pinnatoxins and Portimine by Rachelle Lanceleur, Vincent Hort, Marion Peyrat, Denis Habauzit, Andrew I. Selwood, Valérie Fessard

    Published 2025-01-01
    “…Portimine was the only toxin displaying both a time- and concentration-dependent passage, likely involving a passive diffusion process. …”
    Get full text
    Article
  2. 56482

    Performance of wood bottom ash as a replacement for Portland cement in coating mortars by Leila Celin Nascimento, Gercyr Baptista Junior, Gustavo de Castro Xavier, Afonso Rangel Garcez de Azevedo, Sergio Neves Monteiro, Carla Therezinha Dalvi Borjaille Alledi

    Published 2025-01-01
    “…However, the properties that showed improvement were the setting time and the dynamic elastic modulus. Moreover, it was noticed by the calorimetry analysis that the 5% WBA replacement mortar favored nucleation during hydration. …”
    Get full text
    Article
  3. 56483

    Fully automatic fossa ovalis segmentation from computed tomography images using deep neural network with atlas-based localization by Gakuto Aoyama, Toru Tanaka, Yukiteru Masuda, Naoki Matsuki, Ryo Ishikawa, Masahiko Asami, Kiyohide Satoh, Takuya Sakaguchi

    Published 2025-01-01
    “…At present, this information is obtained manually from pre-procedural medical images, which is time consuming with limited reproducibility. In this paper, we propose a method to automatically segment the FO region from computed tomography (CT) images. …”
    Get full text
    Article
  4. 56484

    MicroRNA-33 regulates the synaptic plasticity-related gene ARC in temporal lobe epilepsy by Yuchen Xu, Lily Zhang, Yan Yan, Wenbiao Xiao, Wei Zou, Zhaohui Luo, Bo Xiao, Hongyu Long

    Published 2025-01-01
    “…We observed that miR-33 levels were reduced at 1 hour and 60 days post-seizure, while ARC expression notably increased at these time points. In the hippocampal CA1 and CA3 regions of post-seizure rats, ARC expression significantly exceeded that of control groups. …”
    Get full text
    Article
  5. 56485

    How Antiretroviral Drug Concentrations Could Be Affected by Oxidative Stress, Physical Capacities and Genetics: A Focus on Dolutegravir Treated Male PLWH by Jessica Cusato, Anna Mulasso, Micol Ferrara, Alessandra Manca, Guido Accardo, Alice Palermiti, Miriam Antonucci, Gianluca Bianco, Francesco Chiara, Jacopo Mula, Maria Cristina Tettoni, Simone Cuomo, Giulia Trevisan, Stefano Bonora, Giovanni Di Perri, Corrado Lupo, Alberto Rainoldi, Antonio D’Avolio

    Published 2025-01-01
    “…Drug concentrations and oxidative stress biomarkers levels were evaluated through liquid chromatography coupled with tandem mass spectrometry, while genetic variants through real-time PCR. No statistical differences were suggested for drug concentrations, with the exception of intracellular DTG (<i>p</i> = 0.047). …”
    Get full text
    Article
  6. 56486

    Simons Observatory: Predeployment Performance of a Large Aperture Telescope Optics Tube in the 90 and 150 GHz Spectral Bands by Carlos E. Sierra, Kathleen Harrington, Shreya Sutariya, Thomas Alford, Anna M. Kofman, Grace E. Chesmore, Jason E. Austermann, Andrew Bazarko, James A. Beall, Tanay Bhandarkar, Mark J. Devlin, Simon R. Dicker, Peter N. Dow, Shannon M. Duff, Daniel Dutcher, Nicholas Galitzki, Joseph E. Golec, John C. Groh, Jon E. Gudmundsson, Saianeesh K. Haridas, Erin Healy, Johannes Hubmayr, Jeffrey Iuliano, Bradley R. Johnson, Claire S. Lessler, Richard A. Lew, Michael J. Link, Tammy J. Lucas, Jeffrey J. McMahon, Jenna E. Moore, Federico Nati, Michael D. Niemack, Benjamin L. Schmitt, Max Silva-Feaver, Robinjeet Singh, Rita F. Sonka, Alex Thomas, Robert J. Thornton, Tran Tsan, Joel N. Ullom, Jeffrey L. Van Lanen, Eve M. Vavagiakis, Michael R. Vissers, Yuhan Wang, Kaiwen Zheng

    Published 2025-01-01
    “…These data will provide new insights into the genesis, content, and history of our Universe, the astrophysics of galaxies and galaxy clusters, objects in our solar system, and time-varying astrophysical phenomena. This ambitious new instrument suite, initially comprising three 0.5 m diameter small aperture telescopes and one 6 m diameter large aperture telescope, is designed using a common combination of new technologies and new implementations to realize an observatory significantly more sensitive than the previous generation. …”
    Get full text
    Article
  7. 56487

    Phenylethanoid glycosides from traditional Mongolian medicine Cymbaria daurica alleviate alloxan-induced INS-1 cells oxidative stress and apoptosis by Ruyu Shi, Xing Li, Bing Gao, Chunhong Zhang, Minhui Li

    Published 2023-09-01
    “…INS-1 cells were treated with C. daurica, cell viability assay, RNA-seq technology, superoxide dismutase activity and malonaldehyde content, quantitative real time-PCR and Western blot analysis were used to study the protective effects of C. daurica. …”
    Get full text
    Article
  8. 56488

    Agile cavity ringdown spectroscopy enabled by moderate optical feedback to a quantum cascade laser by Qinxue Nie, Yibo Peng, Qiheng Chen, Ningwu Liu, Zhen Wang, Cheng Wang, Wei Ren

    Published 2024-11-01
    “…Cavity ringdown spectroscopy (CRDS), relying on measuring the decay time of photons inside a high-finesse optical cavity, offers an important analytical tool for chemistry, physics, environmental science, and biology. …”
    Get full text
    Article
  9. 56489

    From guideline to practice: three years of ICH S11 insights and recommendations by Diana Tavares, Hsiao-Tzu Chien, Hsiao-Tzu Chien, Maria Elzbieta Sheean, Peter Theunissen, Peter Theunissen, Peter van Meer, Peter van Meer, Peter van Meer, Karen Van Malderen

    Published 2025-02-01
    “…Although in 12 of selected PIPs a JAS was already ongoing or completed at the time of submission, in all other cases (115/127), the PIP was submitted before the initiation of JAS. …”
    Get full text
    Article
  10. 56490

    Evaluating the Effect of Chloroform and Water Extract of Satureja khuzistanica on the Expression of Bcl-2 and Bax in Gastric Cancer Cell Line by Bagher Biglak, Asghar Tanomand, Leyla Açik, Farzad Arjomandi Rad, Gholamreza Shahsavari, Saman Kazemi, Hossein Soltanzadeh

    Published 2024-04-01
    “…The expression of Bax and Bcl-2 was evaluated using real-time polymerase chain reaction. Finally, all data were analyzed using REST software. …”
    Get full text
    Article
  11. 56491

    Response surface method-driven design of experiments for the synthesis of fly ash-based geopolymers in the gallic acid optimized removal from wastewater by Ana Paula Ferreira, Ana Paula S. Natal, Arthur P. Baldo, Adriano S. Silva, Jose L. Diaz de Tuesta, Pricila Marin, José A. Peres, Helder T. Gomes

    Published 2025-03-01
    “…Kinetic studies indicated that the pseudo-first-order model best described the adsorption process. At the same time, equilibrium data fitted well with both Langmuir and Freundlich isotherms, with GP_2.0_10_2.5 showing the best fit for the Langmuir model. …”
    Get full text
    Article
  12. 56492

    GATA2 mutated allele specific expression is associated with a hyporesponsive state of HSC in GATA2 deficiency syndrome by Laetitia Largeaud, Vincent Fregona, Laura A. Jamrog, Camille Hamelle, Stéphanie Dufrechou, Naïs Prade, Esmaa Sellam, Pauline Enfedaque, Manon Bayet, Sylvie Hébrard, Mathieu Bouttier, Christine Didier, Bastien Gerby, Eric Delabesse, Marlène Pasquet, Cyril Broccardo

    Published 2025-01-01
    “…This population showed hyporesponsiveness, accumulated over time, and exhibited allele-specific expression (ASE) favoring the mutated Gata2 allele, also observed in GATA2 mutated patients. …”
    Get full text
    Article
  13. 56493

    Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples by Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Vladimir Lyadov, Vladimir Lyadov, Vladimir Lyadov, Maria Suntsova, Marat Garipov, Anna Semenova, Natalia Popova, Egor Guguchkin, Rustam Heydarov, Marianna Zolotovskaia, Xiaowen Zhao, Qing Yan, Ye Wang, Evgeny Karpulevich, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin

    Published 2025-01-01
    “…However, tumor biosamples are usually formalin-fixed paraffin-embedded (FFPE) tissue blocks where RNA is heavily degraded, which in theory may result in decreased efficiency of fusion detection. Here, for the first time, we compared the efficacy of gene fusion detection by RNAseq for matched pairs of freshly frozen in RNA stabilizing solution (FF) and FFPE tumor tissue samples obtained from 29 human colorectal cancer patients. …”
    Get full text
    Article
  14. 56494

    Comprehensive Mass Spectrometric Analysis of Snake Fruit: Salak (Salacca zalacca) by Petra Hlásná Čepková, Michal Jágr, Dagmar Janovská, Václav Dvořáček, Anna Kotrbová Kozak, Iva Viehmannová

    Published 2021-01-01
    “…Among the detected compounds, 11 were reported and quantified for the first time in salak pulp. Chlorogenic acid was by far the most predominant phenolic compound. …”
    Get full text
    Article
  15. 56495

    Forest fire risk assessment model optimized by stochastic average gradient descent by Zexin Fu, Adu Gong, Jinhong Wan, Wanru Ba, Haihan Wang, Jiaming Zhang

    Published 2025-01-01
    “…Therefore, it’s of great importance to research forest fire risk assessment and prediction to protect the ecological environment of forests, respond to disaster damage in time and mitigate the effect of disasters. Most of the current related research methods rely on a stable operating environment and high raw data accuracy, the number of influencing factors considered is always different from the actual in many ways, and there is no systematic validation, etc., which makes the feasibility insufficient. …”
    Get full text
    Article
  16. 56496

    Integrating multi-source monitoring data and deep convolutional autoencoder technology for slope failure pattern recognition by Nana Han, Nana Han, Wending Miao, Mingzhi Li, Mohd Ashraf Mohamad Ismail, Qiang Hu, Liyuan Duan, Liyuan Duan, Jintao Tang

    Published 2025-01-01
    “…The proposed model accurately identified the time and evolution of the landslide, demonstrating its capability to detect failure events effectively.DiscussionValidation results confirm that the model can effectively distinguish previously unseen abnormal modes, offering significant practical value for identifying similar structural anomalies. …”
    Get full text
    Article
  17. 56497

    The Physics Case for an Electron-Muon Collider by Meng Lu, Andrew Michael Levin, Congqiao Li, Antonios Agapitos, Qiang Li, Fanqiang Meng, Sitian Qian, Jie Xiao, Tianyi Yang

    Published 2021-01-01
    “…With this in mind, one can imagine a lepton collider complex, starting from colliding order 10 GeV electron and muon beams for the first time in history and to probe charged lepton flavor violation, then to be upgraded to a collider with 50-100 GeV electron and 1-3 TeV muon beams to measure Higgs properties and search for new physics and finally to be transformed to a TeV-scale muon-muon collider. …”
    Get full text
    Article
  18. 56498

    Evolutionary origins of synchronization for integrating information in neurons by Takashi Shibata, Takashi Shibata, Noriaki Hattori, Hisao Nishijo, Tsutomu Takahashi, Tsutomu Takahashi, Yuko Higuchi, Yuko Higuchi, Satoshi Kuroda, Kaoru Takakusaki

    Published 2025-01-01
    “…Quantum synchronization is hypothesized to involve ion coherence during ion channel passage and the entanglement of photons within the myelin sheath. Unlike the finite-time synchronization seen in chemical and electromagnetic processes, quantum entanglement provides instantaneous non-local coherence states. …”
    Get full text
    Article
  19. 56499

    Whole exome sequencing identifies ABHD14A and MRNIP as novel candidate genes for developmental language disorder by Amal Bouzid, Malek Belcadhi, Amal Souissi, Meryam Chelly, Fakher Frikha, Hela Gargouri, Crystel Bonnet, Fida Jebali, Salma Loukil, Christine Petit, Saber Masmoudi, Rifat Hamoudi, Mariem Ben Said

    Published 2025-01-01
    “…We performed whole-exome sequencing (WES) of a first-time-described Tunisian-family with DLD. Analyses of segregation patterns with stringent filtering of the exome data identified disease-causing compound heterozygous variants. …”
    Get full text
    Article
  20. 56500

    Species diversity of saprophagous flies (Diptera) in hospital grounds of Tehran, Iran by Abbas Ali Mirzakhanlou, Mansoureh Shayeghi, Hassan Vatandoust, Arman Izadian, Zahra Karimi, Kamran Akbarzadeh

    Published 2025-01-01
    “…Sarcophaga nigriventris Meigen, 1826 is reported for the first time for Iranian fauna.…”
    Get full text
    Article