Application of large language models in disease diagnosis and treatment by Xintian Yang, Tongxin Li, Qin Su, Yaling Liu, Chenxi Kang, Yong Lyu, Lina Zhao, Yongzhan Nie, Yanglin Pan, Yuanyuan Ji

“…Future directions include the integration of proprietary clinical knowledge, the investigation of open-source and customized models, and the evaluation of real-time effects in clinical diagnosis and treatment practices.…”
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Can the African weaver ant be used as a vector of entomopathogenic fungi to bolster the biological control of tephritid fruit fly pests? by Thibault Nève de Mévergnies, Samba Diop, Massamba Diakhaté, Claire Detrain, Frédéric Bouvery, Thierry Brévault, Anaïs Chailleux

“…Although the density of dispersed conidia declined over time and distance from the inoculation zone, up to 36% of fruit flies were killed when left to roam on mango trees where conidia had been disseminated by the weaver ants. …”
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Pes Planus Level and Foot Pain Affect Selected Performance Parameters: A Study on Team Sport Athletes by Irma Febriyanti, Hari Setijono, Fransisca Januarumi Marhaendra, Heryanto Nur Muhammad, Fatkhur Rohman Kafrawi, Faridha Nurhayati, Afifan Yulfadinata, Fifukha Dwi Khory, Ahmet Kurtoğlu, Amayra Tannoubi, Karuppasamy Govindasamy, Edi Setiawan

“…Meanwhile, there is a moderate positive correlation with 30mS (p < .001), and MATT (p < .001), which shows that the level of PP will reduce the level of running speed and agility. At the same time, FP-KPI-VAS had a small negative correlation with 30mS (p = 0.017), MATT (p = 0.017) and CMJ (p = 0.048). …”
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Adsorptive removal of toxic heavy metal and dyes from wastewater by rice husk (lignocellulosic biomass) derived activated biochar: A fixed-bed column adsorption study by Md. Mahmudur Rahman, Mohd. Maniruzzaman, Nor ealam, Parvej Mahmud, Sumiya Khatun, Md. Kaowsar Hossain, Md. Ismail Hossain, Md. Hasanuzzaman, Md. Ashraful Alam, Md. Al-amin, Bijoy Chandra Ghos

“…Hence, the newly produced multifunctional FRHBC bioadsorbents would be benificially used to purify real-time industrial wastewater for sustainable environmental protection.…”
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Clinical Guidelines of the Russian Society of Surgeons, the Russian Gastroenterological Association, the Association of Surgeons-Hepatologists and the Endoscopic Society “REndO” o... by V. T. Ivashkin, A. G. Kriger, A. V. Okhlobystin, M. A. Anischenko, S. S. Kardasheva, S. A. Alekseenko, S. F. Bagnenko, M. I. Bykov, S. A. Budzinskiy, I.  M. Buriev, V. A. Vishnevskiy, E. I. Galperin, V. P. Glabay, V. R. Goltsov, T. G. Dyuzheva, G. G. Karmazanovskiy, M. P. Korolev, D. M. Krasilnikov, Yu. A. Kucheryavy, I. V. Maev, N. A. Maystrenko, M. F. Osipenko, M. I. Prudkov, V. I. Simanenkov, E. G. Solonitsin, A. V. Fedorov, E. D. Fedorov, I. B. Khlynov, M. V. Chikunova, A. V. Shabunin, S. G. Shapovalyants, A. A. Sheptulin, O. S. Shifrin

“…The implementation of clinical guidelines can contribute to the timely diagnosis and improve the quality of medical care for patients with chronic pancreatitis.…”
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Emotion dysregulation in youths with obsessive-compulsive disorder and its implication for treatment - An exploratory study from the TECTO trial: A protocol and statistical analysi... by Christine Lykke Thoustrup, Camilla Uhre, Valdemar Uhre, Melanie Ritter, Signe Vangkilde, Janus Engstrøm, Jane Lindschou, Christian Gluud, Anne Katrine Pagsberg, Markus Harboe Olsen

“…We will; 1) assess if emotion dysregulation, measured by the Difficulties in Emotion Regulation Scale (DERS), decreases from baseline to end-of-treatment; 2) compare the proportion of participants with normative emotion regulation to a 90% reference interval from healthy controls (n = 90); 3) use linear regression to examine if baseline emotion dysregulation moderates treatment effects measured by the Children's Yale-Brown Obsessive-Compulsive Scale; 4) investigate if changes in emotion dysregulation mediate treatment effects; and 5) investigate the stability of emotion regulation over time in the healthy controls. Analyses 1–4 will be conducted for all OCD participants and separately for the two treatment groups. …”
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Laryngeal cancer diagnosis based on improved YOLOv8 algorithm by Xin Nie, Xueyan Zhang, Di Wang, Yuankun Liu, Lumin Xing, Wenjian Liu

“…Additionally, a tiny fully convolutional network architecture has been employed, reducing the number of model parameters and computational costs while maintaining or enhancing performance, which is crucial for real-time medical imaging analysis. The experiments utilized a real-world endoscopic image dataset from the hospital, and the results indicated that MSEC-YOLO outperformed the original YOLOv8 model and its multi-kernel versions across multiple evaluation metrics, especially in critical categories such as malignant tumors, polyps, and papillomas, demonstrating extremely high precision and recall rates.…”
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Multifunctional Analysis of CD4+ T-Cell Response as Immune-Based Model for Tuberculosis Detection by Miriam Lichtner, Claudia Mascia, Ilaria Sauzullo, Fabio Mengoni, Serena Vita, Raffaella Marocco, Valeria Belvisi, Gianluca Russo, Vincenzo Vullo, Claudio M. Mastroianni

“…Multifunctional CD4+ T-cell responses could have the potential to identify at single time point subjects without TB infection and patients having active or latent TB.…”
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Lake Iriqui’s Remarkable Revival: Field Observations and a Google Earth Engine Analysis of Its Recovery After over Half a Century of Desiccation by Adil Moumane, Tarik Bahouq, Ahmed Karmaoui, Dahmane Laghfiri, Mohamed Yassine, Jamal Al Karkouri, Mouhcine Batchi, Mustapha Faouzi, Mohamed Boulakhbar, Ali Ait Youssef

“…The revival was monitored using satellite imagery from Landsat 8 and 9 and Sentinel-2A, processed through Google Earth Engine (GEE), with the Normalized Difference Water Index (NDWI) applied to detect water presence. A time-series analysis revealed significant changes in the lake’s surface water extent following the rainfall. …”
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Hydrogen absorption kinetics and microstructural features of TiFe0.8Mn0.2 alloy by Ryun-Ho Kwak, Taeyang Kwak, Da Hye Lee, Sojin Jung, Jang-Won Kang, Seongtak Kim, Tae-Wook Na, Seok Su Sohn, Hyung-Ki Park, Taejun Ha

“…When the samples were hydrogenated under 40 bar of hydrogen at 20 °C, the 20 h annealed sample absorbed 1.6 wt% H2 within the longest time among the three samples. The maximum hydrogen absorption capacities of the three samples were found to be the same, exhibiting a value of 1.81 wt% H2. …”
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SURVEILLANCE OF PARASITIC DISEASES IN BULGARIA by Rumen Harizanov, Violeta Yakimova, Mihaela Videnova, Ognyan Mikov, Aleksandra Ivanova, Eleonora Kaneva, Raina Borisova, Nina Tsvetkova, Iskra Rainova, Zornitca Traykova

“…However, cases of cystic echinococcosis show an upward trend. For the first time, no epidemic outbreaks of trichinellosis were recorded in 2023. …”
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Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis by Hui Liu, Xiaojuan Bi, Ning Yang, Xue Zhang, Bingbing Fang, Nuerbaiti Kusuman, Wenmei Ma, Jing Li, Jin Chu, Li Sun, Liang Li, Guodong Lü, Renyong Lin

“…The iHEPs exhibit morphological features and a glycogen storage function similar to those of mature hepatocytes and demonstrate an upregulation in hepatic gene programs with increasing induction time. Following transplantation, iHEPs were observed surrounding the metacestode lesions in the liver parenchyma of E. multilocularis-infected mice. iHEPs transplantation effectively restored liver function and improved liver injury in the infected mice. …”
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Isocitrate Dehydrogenase 1 and 2 Mutations in Pediatric Neuroblastoma Patients by Emre LEVENTOGLU, Gurses SAHIN, Sule YESIL, Ceyhun BOZKURT, Nazmiye YUKSEK, Ali FETTAH, Sule TOPRAK, Burcak KURUCU BILGIN, Emre CAPKINOGLU, Nilgun EROGLU, Sibel AKPINAR TEKGUNDUZ, Ayse Ulya ERTEM

“…Conclusions: This study demonstrated the relationship between neuroblastoma and IDH mutation for the first time. Because to the fact that the mutation is very heterogeneous, it would be appropriate to conduct a larger series of patients in terms of the impact of the clinical significance of each mutation on the diagnosis and prognosis.…”
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Developing a semi-automated technique of surface water quality analysis using GEE and machine learning: A case study for Sundarbans by Sheikh Fahim Faysal Sowrav, Sujit Kumar Debsarma, Mohan Kumar Das, Khan Mohammad Ibtehal, Mahfujur Rahman, Noshin Tabassum Hridita, Atika Afia Broty, Muhammad Sajid Anam Hoque

“…The approach also offers significant applications for climate resilience and policy-making, as it enables timely identification of deteriorating water quality trends that may impact biodiversity and ecosystem health. …”
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Diagnostics of chronic small intestinal obstruction in patient with ectopic pancreas in the Meckel's diverticulum (case report) by Zinaida A. Lemeshko, O. S. Shifrin, A. V. Korolev, T. L. Lemina, I. A. Sokolina, A. Ye. Leonovich, K. A. Lesko, A. S. Tertychny, V. T. Ivashkin

“…The patient at the same time had frequent liquid stool that indicated presence of incomplete obstruction. …”
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Sarcopenia as a Predictor of Mortality in a Cohort of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography by Giacomo Mulinacci, Clara Benedetta Conti, Alberto Savino, Davide Gandola, Davide Ippolito, Roberto Frego, Alessandro Ettore Redaelli, Marta Maino, Marco Emilio Dinelli

“…Sarcopenia was associated with higher 30-day and 12-month post-ERCP mortality (OR 3.45, <i>p</i> = 0.03; OR 3.87, <i>p</i> = 0.004) and longer hospitalization time (7 vs. 11 days, <i>p</i> = 0.003). Conclusions: SMI is an easy and objective index of sarcopenia that could be used to predict ERCP outcomes. …”
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Illicit drug use derived from wastewater-based epidemiology in Iran, their removal during wastewater treatment, and occurrence in receiving waters by Anvar Asadi, Shabnam Zarei, Nebile Daglioglu, Evsen Yavuz Guzel, Neda Ravankhah

“…A 2-season monitoring program was undertaken for the first time in Iran. Residues of licit and illicit drugs (amphetamine, 3,4-methylenedioxyamphetamine, methamphetamine, codeine, 3,4-methylenedioxymethamphetamine, heroin, cocaine, and methadone) and major metabolites (benzoylecgonine, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and 6-monoacetylmorphine) were analyzed by LC-MS/MS in composite sampling after solid phase extraction method. …”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…This features live-cell imaging of PI3K/AKT activity reporters and multiplexed CyTOF measurements of PI3K/AKT and RAS/ERK signaling markers over time. Using this framework, we found that the PIK3CA H1047R oncogene was not a simple, constitutive activator of the pathway as often presented. …”
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Branched-Chain Amino Acids (BCAAs): Revisiting Their Role in Sport and Health by Aleksandra Kajtel, Anna Skowronek, Martyna Piekarska, Katarzyna Dąbek, Michał Ochwat, Maria Sudoł, Gabriela Mierzwa

“…Safety data indicates leucine is well-tolerated at dosages up to 0.53 g/kg/day, but optimal dosages and timing require further study. Despite promising findings, the efficacy of BCAA supplementation is context-dependent, highlighting the need for longer trials and research targeting specific populations, including the elderly and those with chronic illnesses. …”
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Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: A genomic epidemiology study by Gillian AM Tarr, Linda Chui, Kim Stanford, Emmanuel W Bumunang, Rahat Zaheer, Vincent Li, Stephen B Freedman, Chad R Laing, Tim A McAllister

“…To assess the impact of persistent cross-species transmission systems on the epidemiology of E. coli O157:H7 in Alberta, Canada, we sequenced and assembled E. coli O157:H7 isolates originating from collocated cattle and human populations, 2007–2015. We constructed a timed phylogeny using BEAST2 using a structured coalescent model. …”
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