Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT by Bibo Yuan, Citlalli Osorio-Yáñez, Junkai Fang, Lei Zhao, Ander Wilson, Marco Sanchez-Guerra, Hongbin Liu, Peng-Hui Li, Liqiong Guo

“…Our results show, for the first time, that vibration exposure is associated with an increased risk of thyroid disease and elevated TSH levels. …”
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Medium-term load forecasting with Power Market Survey: GEPCO case study by Sheeza Mariam Nawaz, Ubaid Ahmed, Adil Amin, Syed Afraz Hussain Shah, Anzar Mahmood

“… This research presents a comprehensive case study on medium-term load forecasting (MTLF) in the intricate dynamics of Pakistan’s power sector, Gujranwala Electric Power Company (GEPCO). The time horizon for MTLF ranges from a few weeks to one year and it has applications in energy management and planning. …”
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Illicit drug use derived from wastewater-based epidemiology in Iran, their removal during wastewater treatment, and occurrence in receiving waters by Anvar Asadi, Shabnam Zarei, Nebile Daglioglu, Evsen Yavuz Guzel, Neda Ravankhah

“…A 2-season monitoring program was undertaken for the first time in Iran. Residues of licit and illicit drugs (amphetamine, 3,4-methylenedioxyamphetamine, methamphetamine, codeine, 3,4-methylenedioxymethamphetamine, heroin, cocaine, and methadone) and major metabolites (benzoylecgonine, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and 6-monoacetylmorphine) were analyzed by LC-MS/MS in composite sampling after solid phase extraction method. …”
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Oncogenic PIK3CA corrupts growth factor signaling specificity by Ralitsa R Madsen, Alix Le Marois, Oliwia N Mruk, Margaritis Voliotis, Shaozhen Yin, Jahangir Sufi, Xiao Qin, Salome J Zhao, Julia Gorczynska, Daniele Morelli, Lindsay Davidson, Erik Sahai, Viktor I Korolchuk, Christopher J Tape, Bart Vanhaesebroeck

“…This features live-cell imaging of PI3K/AKT activity reporters and multiplexed CyTOF measurements of PI3K/AKT and RAS/ERK signaling markers over time. Using this framework, we found that the PIK3CA H1047R oncogene was not a simple, constitutive activator of the pathway as often presented. …”
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Frontal Face Generation Based on Attitude Point Guidance and Attention Mechanism Improvement by Jihui Zhao, Zhengyi Yuan, Junhu Zhang, Haitao Li, Hui Li

“…In the generator part, the self-attention mechanism is introduced to obtain the dependence between feature points and other position features, which enhances the illumination perception ability of the network layer. At the same time, local attention is used in a discriminator to improve the local detail generation ability of the network in the face. …”
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Comprehensive evaluation of the nutritional value and contaminants of alfalfa (Medicago sativa L.) in China by Xiaoyan Zhu, Xiaoyan Zhu, Xiaoyan Zhu, Wenxue Chen, Mengyao Li, Boshuai Liu, Boshuai Liu, Boshuai Liu, Shumin Zhao, Menglin Hu, Jiajing Li, Defeng Li, Defeng Li, Defeng Li, Yinghua Shi, Yinghua Shi, Yinghua Shi, Hao Sun, Hao Sun, Hao Sun, Chengzhang Wang, Chengzhang Wang, Chengzhang Wang

“…The over-standard rates of total bacteria count and total mould count were 66.7% and 75.8%, respectively, while the over-standard rate of chromium in heavy metals was as high as 87.9%.DiscussionThis study establishes the nutrient composition and harmful component profiles of alfalfa hay in five major planting areas for the first time, which provides a valuable reference for the safe and sustainable utilisation of alfalfa in livestock feed.…”
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Divergence of alpine plant populations of three Gentianaceae species in the Qinling sky Island by Peng-Cheng Fu, Bing-Jie Mo, He-Xin Wan, Shu-Wen Yang, Rui Xing, Shan-Shan Sun

“…A high level of genetic differentiation was observed among the Qinling populations and the other populations of each species. Divergence time estimation based on plastomes and approximate Bayesian computation based on genomic SNPs showed that Qinling populations of the three Gentianaceae species originated at different periods under various patterns including primary source and hybridization. …”
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Technical, economic and lifecycle greenhouse gas emissions analyses of solid sorbent direct air capture technologies by Sylvanus Lilonfe, Sarah Rodgers, Amir F.N. Abdul-Manan, Ioanna Dimitriou, Jon McKechnie

“…The costs of DAC are heavily influenced by: (i) economic factors (i.e. capital expenses and energy costs), (ii) design elements (i.e. plant scale) and (iii) technical parameters (i.e. sorbent's adsorption rate and time). Conversely, the GHG emissions of DAC are mostly determined by the source of energy. …”
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Continuous follow-up intervention of a low-salt diet to control blood pressure among older people with hypertension in rural Indonesia by Ivana Aprilia Pehopu, Andi Masyitha Irwan, Elly Lilianty Sjattar, Sakul Changmai, Noor Azah Abd Aziz

“…The intervention group received a one-time low-salt diet education and 2-month follow-up. …”
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Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells by Xuanhe Fu, Zhixiong Yu, Fang Fang, Weiping Zhou, Yuxin Bai, Zhongjia Jiang, Biao Yang, Ye Sun, Xing Tian, Guangyan Liu

“…In addition, the analysis from RNA-seq and real-time RT-PCR revealed that CBD activated the endoplasmic reticulum (ER) stress pathway. …”
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Efficiency of a macroroughness block ramp in reducing the impact of low-head dams on riverine fish dispersion by Tomanova Sylvie, Courret Dominique, Richard Sylvain, Mercier Olivier, Guillemin Axel, Labedan Mathilde, Sagnes Pierre

“…Fish between 70 and 451 mm in total length were detected crossing the ramp, usually within a short time. In comparison with the efficiency results available for other types of fishways, the macroroughness ramp studied here ranks among the most efficient devices for fish movement restoration.…”
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From guideline to practice: three years of ICH S11 insights and recommendations by Diana Tavares, Hsiao-Tzu Chien, Hsiao-Tzu Chien, Maria Elzbieta Sheean, Peter Theunissen, Peter Theunissen, Peter van Meer, Peter van Meer, Peter van Meer, Karen Van Malderen

“…Although in 12 of selected PIPs a JAS was already ongoing or completed at the time of submission, in all other cases (115/127), the PIP was submitted before the initiation of JAS. …”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…Given the relevance of inflammatory reaction, anticytokines therapy, in particular the inhibition of interleukin 1 (IL-1), seems to be the most promising strategy. At the present time, intra-articular injection of IL-1 receptor antagonist is the only anticytokine approach that has been used in a human study of PTA. …”
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Assessment of energy management and power quality improvement of hydrogen based microgrid system through novel PSO-MWWO technique by Hafiz Ghulam Murtza Qamar, Xiaoqiang Guo, Ehab Seif Ghith, Mehdi Tlija, Abubakar Siddique

“…This substantiates its practical utility in real-time applications. The efficacy of this method is empirically demonstrated through the implementation in MATLAB software.…”
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Experimental identification of I-mode characteristics at the edge of FIRE mode in KSTAR by Chweeho Heo, SangJin Park, GyungJin Choi, Jaewook Kim, Eun-jin Kim, YoungMu Jeon, Minjun J. Choi, Hyunsun Han, Choongki Sung, TaikSoo Hahm, Yong-Su Na

“…The edge region of the recently discovered fast ion-regulated enhancement mode (FIRE mode) (Han and Park et al 2022 Nature 609 269–275), which primarily operates in the unfavorable ion $\nabla B$ drift configuration, is investigated in detail for the first time. An ion temperature pedestal is identified, while the edge electron density profile remains at low-confinement mode (L-mode) level, displaying characteristics of the edge profiles in improved energy confinement mode (I-mode). …”
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Complex and severe infection in a 67-year-old liver transplant recipient due to Cunninghamella elegans, Bordetella bronchiseptica, and Pneumocystis jirovecii by Muyun Wei, Kangyi Gu, Juanxiu Qin, Xinhua Lu, Junqi Feng, Shaowei Mao, Min Li, Zhilan Li, Changsheng Wang

“…Also, the case indicates that traditional methods are insufficient for the etiological diagnosis needs of critical and severe patient populations, and timely use of mNGS should be recommended.…”
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Efficacy of 3D-printed patient specific implant for orbital wall fracture repair in a series of 40 patients by Min Kyu Yang, Seong Jung Ha, Gye Jung Kim, Junhyeok Ock, Namkug Kim, Ho-Seok Sa

“…All orbital fractures (inferior wall, 19; medial wall, 9; and combined inferior and medial walls, 12) were successfully repaired without postoperative complications. The mean time for implant insertion during surgery was 19.8 s (range, 3–60). …”
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Individual variability in cortical representations of tonic pain by Bettina Deak, Anne Stankewitz, Astrid Mayr, Viktor Witkovsky, Pauline Jahn, Enrico Schulz

“…In a whole-brain approach, we related the dynamic fluctuations of cortical activity and connectivity to the time courses of pain. We also explored the variability of cortical processing across participants. …”
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Hydrogen production by methane decomposition over Ni-doped activated carbons: effect of the activation method by Mahmoudi, Marwa, Dufour, Anthony, Bettahar, Mohammed El-Miloud, Medjahdi, Ghouti, Ouederni, Abdelmottaleb, Gadiou, Roger

“…The catalysts showed good initial activities that increased with temperature and nickel load, reactivity decreased with time. The reaction orders were 0.63 and 0.74 and the activation energies were 122 and 139 kJ/mol for physically and chemically activated carbon, respectively. …”
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A review of metabolic calorimetric applications in plant stress, waste management, and diagnostics by Michael Bayode, Ifeoluwaposi Ogundana, Oluwatosin Ogundare, Elizabeth Awodire, Patience Abbah, Israel Onifade, Adeola Adeyolanu, Stephen Okunade, Samuel Ogboye, Michael Elabiyi

“…The ongoing integration of DSC techniques with cutting-edge analytical methodologies could also permit the implementation of Smart, Measurable, Achievable, Relevant, Time-bound (SMART) goals for a precise and quantifiable strategy in environmental impact assessments.…”
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