Elritercept, a modified activin receptor IIA ligand trap, increased erythropoiesis and thrombopoiesis in a phase 1 trial by Jennifer Lachey, Christopher Rovaldi, Suresh Bobba, Jared Tur, Harveen Natarajan, Ben Snyder, Jasbir Seehra

“…Elritercept elicited rapid, sustained, and dose-dependent increases in reticulocytes, red blood cells, hemoglobin, and platelets without eliciting detrimental changes in white blood cells such as neutrophils and lymphocytes. The time course and duration of changes in these cell populations supported a differentiated pharmacologic profile that is consistent with the stimulation of both early- and late-stage hematologic pathways. …”
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Anti-Inflammatory Activity of Ferula assafoetida Oleo-Gum-Resin (Asafoetida) against TNF-α-Stimulated Human Umbilical Vein Endothelial Cells (HUVECs) by Leila Mobasheri, Mohsen Khorashadizadeh, Hossein Safarpour, Maryam Mohammadi, Gholamreza Anani Sarab, Vahid Reza Askari

“…Gene expression of intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin and surface expression of ICAM-1 protein were measured using real-time PCR and flow cytometry methods, respectively. …”
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Prevalence of Hypercalcaemia in a Renal Transplant Population: A Single Centre Study by Tony Amin, P. Toby Coates, Jeffrey Barbara, Paul Hakendorf, Nazmul Karim

“…Inclusion criteria include kidney transplant patients with functioning graft since 1971 and at least 3 months after transplantation at the time of analysis. Hypercalcaemia was defined as persistently elevated serum corrected calcium greater than or equal to 2.56 mmol/L for three consecutive months. …”
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Neonatal Screening for Congenital Hypothyroidism: A Study Conducted in a Tertiary Care Hospital of Gujarat by Shubhangi Rathod, Ramesh Pradhan, Rosy Lekharu, Jaydip Vala, Mehak Kulshrestha

“…Cord blood was collected at the time of delivery, and dried blood spots (DBS) from heel prick at 72 hours were collected and TSH was compared. …”
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Using artificial intelligence tools for automating the assessment of future computer science teachers' work by Oleksandr M. Spazhev, Oksana V. Klochko

“…This approach makes it possible to solve the following tasks: reducing the time and effort required for manual checking of programming tasks completed by students; promoting better assimilation of the material of the relevant disciplines by students; promoting the development and improvement of students' skills in algorithmisation and programming; compliance by students with academic integrity; effective use of GitHub Copilot to generate baseline tests to test modified programming assignments completed by students; ensuring the flexibility and scalability of the approach to the development of various training courses in programming; development of students' software product testing skills. …”
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Cohort profile: the Halland osteoarthritis (HALLOA) cohort–from knee pain to osteoarthritis: a longitudinal observational study in Sweden by Ann Bremander, Maria L E Andersson, S Bergman, Katarina Aili, Emma Haglund

“…We also found that modifiable factors as increased visceral fat and total body fat were associated with increased pain sensitivity among individuals with knee pain.Future plans By studying possible pathophysiological mechanisms of OA over time, we aim to provide new insights on OA progression, identify usable preventive measures helping the clinicians in the management of the disease and improve health for the patients. …”
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Development of an algorithm impacting COPD care through personalized nutrition and IoT-based monitoring by Prachi Sharma, Mihir Gharia, Devina Aswal, Vishva Trivedi, Bhavnita Soni, Prerna Soni, Devesh Joshi, Dhvni Lalan, Vrushali Athavale, Irfan Shaikh, Koshy Jacob

“…Conclusion The comprehensive features and functionalities of the MyTatva app, combined with the personalized care plan and real-time feedback mechanisms, have led to substantial clinical improvements in COPD management. …”
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Clinical Comparison of Fusarium Keratitis according to the Initial Potassium Hydroxide (KOH) Smear: A Retrospective Study in South Korea by Jong Ha Kim, Hyeon Jeong Yoon, Kyung Chul Yoon, In Cheon You

“…Differences were observed between the KOH-positive group and the KOH-negative group in terms of deep corneal infiltration (50.0% vs. 78.7%, p=0.008) and evisceration treatment (3.1% vs. 25.5%, p=0.008). The delayed time to initiate antifungal eye drops was longer in the KOH-negative group (1.13 ± 0.49 vs. 3.93 ± 4.89, p=0.002). …”
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Molecular Identification of Fusarium proliferatum from toenails: A case report by Sazan Jamal Gharib, Nawroz Abdul-razzak Tahir

“…Designation of the ordinary laboratory of Fusarium is very challenging because of the septate hyphae of Fusarium are hard to discriminate from those of Aspergillus, which has a more favourable consequence and this time-consuming. Therefore, molecular tools were used for identification of F. proliferatum from this case by amplifying ITS region of rDNA using a pair of universal primers ITS1 and ITS4. …”
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Technological properties of grain and flour in bread wheat (<i>Triticum aestivum</i> L.) genotypes carrying two loci that determine the endosperm structure by A. V. Simonov, T. A. Pshenichnikova

“…Targeted selection made it possible to obtain lines similar to the SSL line in terms of milling performance and flour strength.Conclusion. For the first time, a set of supersoft-grain lines with special properties of grain and flour was obtained on the genetic basis of three spring cultivars. …”
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Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice by Elle EM Scheijen, Naomi Veeningen, Sam Duwé, Anna Ivanova, Jana Van Broeckhoven, Sven Hendrix, David M Wilson

“…Results: Our analysis revealed that increased DNA damage foci were present from 1 hpi to 3 dpi in SCI mice relative to controls (sham surgery and naive), with the damage signal spreading over time longitudinally from the affected area to more rostral and caudal regions. …”
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Investigation of the healing effects of Afyon Province hot spring waters on experimentally-induced fatty liver in mice by Bülent Elitok, Ibrahim Kişlalioğlu, Yavuz Ulusoy, Bahadır Kilinç

“…The results of histopathological analysis also demonstrated positive dynamics. At the same time, no pronounced positive dynamics was observed in animals of the control group. …”
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Analysis of water based Casson hybrid nanofluid (NiZnFe2O4+MnZnFe2O4) flow over an electromagnetic actuator with Cattaneo–Christov heat-mass flux: A modified Buongiorno model by S. Baskaran, R. Sowrirajan, S. Divya, S. Eswaramoorthi, K. Loganathan

“…The Lewis number and mass relaxation time parameter declines the nanofluid concentration profile. …”
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Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later by Tore K Kvien, Hilde Berner Hammer, Ida K Haugen, Barbara Slatkowsky-Christensen, Alexander Mathiessen

“…We applied logistic regression with generalised estimating equations adjusted for age, sex, body mass index and follow-up time.Results Ultrasound demonstrated osteophytes in 86/301 (28.6%) joints without radiographic OA and 392/717 (54.7%) joints without clinical bony enlargement. …”
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Molecular cytological analysis of alien introgressions in common wheat lines created by crossing of <i>Triticum aestivum</i> with <i>T. dicoccoides</i> and <i>T. dicoccum</i> by О. A. Orlovskaya, I. N. Leonova, L. A. Solovey, N. I. Dubovets

“…A molecular cytogenetic analysis of introgression wheat lines indicated that the inclusion of the genetic material of wild and domesticated emmer was carried out mainly in the form of whole arms or large fragments in the chromosomes of the B genome and less extended inserts in the A genome. At the same time, the highest frequency of introgressions of the emmer genome was observed in chromosomes 1A, 1B, 2B, and 3B. …”
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GOVERNANCE MATTERS: INSIGHTS INTO EUROPEAN UNION FUND ABSORPTION ACROSS SUCCESSIVE MULTIANNUAL FINANCIAL FRAMEWORKS by Diana BĂLAN, Ana-Cristina NICOLESCU

“…The study uses a comprehensive dataset for 27 EU Member States from 2007 to 2022. This time frame covers the last two multiannual financial frameworks (MFFs): 2007-2013 and 2014-2020. …”
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First density estimates of the Endangered Claire's mouse lemur Microcebus mamiratra and recommendations for its conservation by Luke D. Martin, Herison Razafimanantsoa, Eva S. Nomenjanahary, Sylviane Volampeno, Alison M. Behie

“…Our population estimate will inform future conservation status assessments and conservation planning for this range-restricted species and provide a baseline for monitoring population changes over time. We present recommendations for the conservation of M. mamiratra and highlight the potential for lemur watching, sustained by the strong tourism industry on Nosy Be, to help protect lemur habitat and generate economic opportunities for local communities.…”
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Ballistic Impact Performance of SiC Ceramic-Dyneema Fiber Composite Materials by Kai-Kuang Wu, Yu-Liang Chen, Jau-Nan Yeh, Wei-Lun Chen, Chia-Shih Lin

“…Subsequently, the correlation function of the relationship between the combined thickness of the composite material and its ballistic resistance was determined through the experimental design, which effectively reduced the simulation analysis time. According to simulation experiments and regression analysis, the equation for the relationship between the combined thickness of the composite material and its ballistic resistance was EAhc,hf=−6276.5+500.6hc+1512.6hf+30.7hchf−8.1hc2−113.6hf2, though there were limitations to its application. …”
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Legal regulation of inheritance relations under martial law by V. P. Makovii, O. I. Yakymets, Z. I. Knysh

“…It has been examined the restrictions on the rights and freedoms of participants to inheritance relations precisely because of their temporal component in the following areas: determining the place of time values in the relevant mechanism of legal regulation using the example of the period of inheritance acceptance; establishing the hierarchy of regulations which introduce such restrictions; and novelizing the relevant regulatory provisions. …”
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Evaluation of Wide Corneal Epithelial Remodeling after Small Incision Lenticule Extraction (SMILE) with Wide-Field Optical Coherence Tomography by Yiming Ye, Pei Chen, Na Yu, Linxi Wan, Min Lan, Hua Zheng, Keming Yu

“…The ET changes were compared among the different time points and analyzed zones. Results. The ET increases from one week to three months and stabilized from three months to six months. …”
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