A Systematic Review and Network Meta-Analysis on the Efficacy of Medications in the Treatment of Chronic Idiopathic Constipation in Japan by Atsushi Nakajima, Ayako Shoji, Kinya Kokubo, Ataru Igarashi

“…Elobixibat 10 mg was ranked first for the increase in SBMs and complete SBMs within 1 week and the time to first SBM. Lubiprostone 48 μg was ranked first for the proportion of patients with SBM within 24 hours. …”
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“The Word for the New Year” by Archimandrite Anastasius (Alexandrov): Speech-Behavioral Analysis by A.Ju. Chernysheva

“…The paper is of high value, because the historical component of the speech-behavioral tactics used by Archimandrite Anastasius, who raised questions about false and true communicative values in the early 20th century, remains relevant in our time. As a result of the study, groups have been singled out representing the speech-behavioral tactics of debunking the desire for wealth, pleasure, fame and power, fetish of knowledge, carnal attachments, as well as a group of such speech-behavioral tactics that appeal to faith in the God. …”
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The Role of Subtropical High Pressure in the Spatial Daily Precipitation Distribution in Iran by Amir Hosein Halabian, Mehran Shabankari

“…According to this analysis, the occurrence of precipitation in 96.9% of studied stations(1033 out of 1066) are intensively under control of subtropical high pressure at the time of the predominance of this system over Iran.…”
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From Waste to Resource: Use of <i>Lemna minor</i> L. as Unconventional Fertilizer for Lettuce (<i>Lactuca sativa</i> L.) by Ada Baldi, Leonardo Verdi, Lorenzo Piacenti, Anna Lenzi

“…Therefore, its use as an alternative to commercial fertilizers can allow farmers to profitably exploit a waste product and, at the same time, reduce the costs for fertilization, thus achieving environmental and economic benefits.…”
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Smartphone Applications for Period Tracking: Rating and Behavioral Change among Women Users by Reema A. Karasneh, Sayer I. Al-Azzam, Karem H. Alzoubi, Suhaib M. Muflih, Sahar S. Hawamdeh

“…Most of the apps enabled setting user goals, motivations, and interactivity, tracking multiple symptoms or mood changes, allowed notifications, and used graphs to illustrate the tracking result over a specific period of time. The majority of features and functions within these apps were offered for free, while some apps included limited in-app purchases or needed Internet connection to function. …”
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Global birth prevalence of major congenital anomalies: a systematic review and meta-analysis by Xiaolong Xie, Jiao Pei, Li Zhang, Yang Wu

“…Data from eligible studies were pooled in meta-analysis to get global estimates of birth prevalence and prevalence in subgroups of geographic regions, countries with varying income levels and time periods. Results One hundred and twenty-three studies including a total of 256,507 cases of congenital anomalies and 769,455,220 births were included in this study. …”
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How is depth of anaesthesia assessed in experimental pigs? A scoping review. by Alessandro Mirra, Ekaterina Gamez Maidanskaia, Luís Pedro Carmo, Olivier Levionnois, Claudia Spadavecchia

“…No limits were set for time, language and study type. Only original articles of in vivo studies using pigs or minipigs undergoing general anaesthesia were included. …”
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The Red Supergiant Progenitor Luminosity Problem by Emma R. Beasor, Nathan Smith, Jacob E. Jencson

“…The robustness of these assumptions is difficult to test since we cannot go back in time and obtain additional pre-explosion imaging. …”
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Treatment Interruption and Regimen Change in Firstgeneration versus Second-generation Tyrosine Kinase Inhibitors used as First-line Therapy for Chronic Myeloid Leukemia by Melea A. Ward, Gang Fang, Kristy L. Richards, Christine M. Walko, Stephanie R. Earnshaw, Laura E. Happe, Susan J. Blalock

“…Patients initiating therapy with a 2GTKI had a 48% higher risk of treatment interruption versus patients initiating therapy with a 1GTKI (hazard ratio=1.48, 95% confidence interval 1.08-2.02). The time to treatment interruption was significantly longer in patients initiating therapy with a 1GTKI. …”
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Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy by Jianbo He, Hong Wang, Ying Liu, Wen Li, Dorothy Kim, Hu Huang

“…Protein expression and localization were examined by western blots (WB) and immunofluorescence (IF). mRNA expression was quantified by PCR array and real-time PCR. The activity of VEGFR1 signaling was blocked by a neutralizing antibody called MF1. …”
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Prevalence of Early Postnatal-Care Service Utilization and Its Associated Factors among Mothers in Hawassa Zuria District, Sidama Regional State, Ethiopia: A Cross-Sectional Study by Shambel Yoseph, Azmach Dache, Aregahegn Dona

“…Strengthening family planning services, giving information on obstetrics danger signs, and creating awareness about postnatal care will improve uptake of the service in a timely manner.…”
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Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes by Chunzi Liang, Benjamin J. Curry, Patricia L. Brown, Michael B. Zemel

“…Furthermore, leucine treatment for 24 hours resulted in time-dependent increases in cellular NAD+, SIRT1 activity, and p-AMPK level, with SIRT1 activation preceding that of AMPK, indicating that leucine activation of SIRT1, rather than AMPK, is the primary event.…”
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Exploring the mechanism of berberine treatment for atherosclerosis combined with non-alcoholic fatty liver disease based on bioinformatic and experimental study. by Shushu Wang, Kachun Lu, Liwen Lin, Gaijie Li, Yuxin Han, Zhichao Lin, Qingmin Chu, Kunsheng Wu, Peijian Liu, Guiting Zhou, Rui Peng, Chuanjin Luo

“…The efficacy and mechanism of action of BBR were verified using methods such as hematoxylin and eosin (HE) staining, Oil Red O staining, and real-time quantitative PCR (RTqPCR). Through transcriptome analysis, WGCNA, and machine learning, this study identified 48 key genes involved in both AS and NAFLD. …”
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Functional constipation by Yu. O. Shulpekova, A. A. Kurbatova, A. V. Sedova

“…In the section devoted to the bowel diseases the new entity - opioid-induced constipation was defined; besides that diagnostic (mostly - the time-based criteria) of irritable bowel syndrome and functional constipation were modified. …”
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The staffing problem in the police during 1943–1944 and ways to resolve it by V. A. Grechenko

“…The educational level of newly recruited police officers was very low at the time. Thus, of those recruited to the state police, only 7.6 % had special training, 3.1 % had military education, and 10.6 % had a secondary education. …”
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Effect of Existential Group Therapy on the Quality of Sexual Life in Infertile Men\'s Spouses by samira ghorbani, Shahrbanoo Salehin, Ali Mohamad Nazari, Seyedeh Solmaz Talebi, Afsaneh Keramat

“…The analysis of the mean difference in the quality of sexual life scores between the two time points for the intervention and control groups revealed a significant difference (P<0.001). …”
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Gene expression profiling in B-cell non-Hodgkin lymphomas by Renas N. Saleem, Ahmed Khudair Yassin

“…The integration of gene expression biomarkers uses quantitative real-time polymerase chain reaction technique to diagnose B-NHL. …”
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Effects of Partial Supporting Pile Removal from Deep Foundation Pits by Shallow Excavation Method in Loess Areas by Yunxin Zheng, Zhiping Hu, Xiang Ren, Rui Wang, Enxiang Zhang, Zhao Long

“…In the process of removing the supporting piles, the Earth pressure behind the piles is redistributed, and the load is mainly transferred to the adjacent supporting piles outside the tunnel within the radius of one time of the tunnel diameter. However, the load is not evenly transferred to the adjacent supporting piles. …”
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A Structural Equation Model For Adopting Additive Manufacturing in the Footwear Firms Supply Chains by Tekalign Lemma, Endalkachew Mosisa Gutema, Hirpa G. Lemu, Mahesh Gopal

“…The findigs of the study confirmed that additive manufacturing best practices (time, inventory, operation, and resource, energy and waste related factors) have positive effects on static and dynamic supply chain complexity. …”
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Validation of the Kidney Failure Risk Equation in the Colombian Population by C. Larrarte, J. Vesga, F. Ardila, A. Aldana, D. Perea, M. Sanabria

“…The discriminatory capacity of the model was evaluated by the concordance index using Harrell’s C statistic, and the time-dependent area under the receiver operating characteristic (ROC) curve was estimated using the nearest neighbor method, as well as the optimal cut-off point for sensitivity and specificity. …”
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