IgA肾病患者血清IgA1对足细胞凋亡的影响

“…【方法】 Jacalin 亲和层析和Sephacryl S-200 分子筛用来纯化蛋白,单体IgA1(mIgA1)热聚合为聚合体IgA1(aIgA1), 同步化的足细胞与患者和健康对照来源的aIgA1共培养,流式细胞仪评价细胞凋亡情况,Real time PCR 检测Bcl-2, Bax, Fas and Fas-L mRNA表达情况。 【结果】 IgAN患者的aIgA1可诱导足细胞的凋亡,其凋亡率显著高于对照组[(30.5 ± 5.4)% vs (20.6 ± 4.5)%, P < 0.05];而健康对照的aIgA1可诱导足细胞的凋亡,凋亡率也显著高于对照[(31.4 ± 5.3)% vs (20.6 ± 4.5)%,P < 0.05];IgAN患者的aIgA1诱导足细胞的凋亡呈现时间和浓度依赖?…”
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Principles of teaching professionally-oriented foreign language in virtual reality by Polina G. Labzina, Maksim V. Gureev, Maksim E. Zhabin, Evgenij I. Novalov

“…The implementation of the teaching principles mentioned above by means of virtual reality, makes it possible to create educational conditions that meet the requirements of the time and contribute to increasing the effectiveness of teaching not only foreign languages but also other disciplines. …”
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Cytogenetic impact of gamma radiation and its effects on growth, yield and drought tolerance of maize (Zea mays L.) by Walaa M. Al-Sayed, Hanaa H. El-Shazly, Awatif I. El-Nahas, Ahmed A. A. Omran

“…Additionally, molecular polymorphism induced by both gamma irradiation and drought stress was analyzed using Real-Time quantitative PCR techniques for DREB2, ERF, and EF transcription factors. …”
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Optimizing in vitro fertilization in four Caribbean coral species by Valérie F. Chamberland, Matthew-James Bennett, Tania Doblado Speck, Kelly R. W. Latijnhouwers, Margaret W. Miller

“…., Diploria labyrinthiformis, Colpophyllia natans, Pseudodiploria strigosa, Orbicella faveolata) to determine sperm concentration, gamete age, and co-incubation time resulting in the highest fertilization success. …”
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The Clinical and Steroid-Free Remission of Fecal Microbiota Transplantation to Patients with Ulcerative Colitis: A Meta-Analysis by Wai Ching Lam, Chen Zhao, Wen Juan Ma, Liang Yao

“…Moreover, a common consensus on the route, volume, timing, preferred donor characteristics, and frequency of fecal administration is necessary to achieve remission.…”
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Hepatitis C Prevalence on the Rise but Screening at Safety Net Institutions Lagging behind by Jarin Prasa, Syed S. Karim, Bobby Jacob, Paul Mustacchia

“…Previous guidelines recommended one-time screening for individuals born between 1945 and 1965. …”
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Phytosanitary monitoring of the narrow-leaved lupine collection of VIR in the northwest of Russia by R. A. Abdullaev, M. A. Vishnyakova, G. P. Egorova, E. E. Radchenko

“…The dominant pest was the lupine aphid (Macrosiphum albifrons Essig), discovered in Russia for the first time. A whole set of fungal pathogens was identified, among which the most common and harmful were the causative agents of Fusarium, brown leaf spot, powdery mildew, gray mold, and Sclerotinia stem rot. …”
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Efficiency of a macroroughness block ramp in reducing the impact of low-head dams on riverine fish dispersion by Tomanova Sylvie, Courret Dominique, Richard Sylvain, Mercier Olivier, Guillemin Axel, Labedan Mathilde, Sagnes Pierre

“…Fish between 70 and 451 mm in total length were detected crossing the ramp, usually within a short time. In comparison with the efficiency results available for other types of fishways, the macroroughness ramp studied here ranks among the most efficient devices for fish movement restoration.…”
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A feasibility study on using soft insoles for estimating 3D ground reaction forces with incorporated 3D-printed foam-like sensors by Nick Willemstein, Saivimal Sridar, Herman van der Kooij, Ali Sadeghi

“…Four participants participated in three trials over a week, which showed a decrease in estimation performance over time but stayed on average 11.35% RMS and 8.6% MAE after a week with the performance seeming consistent between days two and seven. …”
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Self-regulated learning strategies adopted by successful Chinese nursing students in the process of learning Nursing English. by Lina Wang, Xuesong Andy Gao, Fan Zhang, Fang Sun, Guangsheng Wan

“…To surmount these challenges, the participants adopted diverse self-regulated learning strategies, including setting goals, previewing in advance and reviewing in time, utilizing word roots, prefixes, and suffixes to facilitate vocabulary learning, repeating, practicing with sounds and writing systems, translating, highlighting and using imagery to overcome language-related challenges; believing in the usefulness and significance of Nursing English, keeping a growth mindset, enjoying Nursing English learning and teacher support and maintaining grit in learning Nursing English to overcome learner-related challenges; and integrating resources, creating supportive language environments and seeking assistance from teachers and cooperating with peers to overcome context-related challenges. …”
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Sensitivity Analysis of Biosensor-Based SiGe Source Dual Gate Tunnel FET Having Negative Capacitance by Dipshika Das, Rudra Sankar Dhar, Pradip Kumar Ghosh, Yash Sharma, Amit Banerjee

“…Finally, RF analyzes are carried out to explore the benefits of using negative capacitance where the biosensor acts as an intrinsic voltage amplifier exhibiting superior gain-bandwidth product (GBP) and cut-off frequency (fT), indicating its potential for high-speed operation and real-time sensing applications. The research yields repeatable outcomes for several calculated analyses.…”
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Toward GIC Forecasting: Statistical Downscaling of the Geomagnetic Field to Improve Geoelectric Field Forecasts by C. Haines, M. J. Owens, L. Barnard, M. Lockwood, C. D. Beggan, A. W. P. Thomson, N. C. Rogers

“…It would be beneficial for power grid operators to have a forecast of GICs that could inform decision making on mitigating action. Long lead‐time GIC forecasting requires magnetospheric models as drivers of geoelectric field models. …”
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The causes and numbers of hospital admissions and deaths during the Korean War by Kun Hwang, Hun Kim, Chan Yong Park

“…Among the common causes of death, percentages of wounds and wound by fragments decreased over time; however, the deaths from respiratory disease increased. …”
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Waste Foundry Sand as Permeable and Low Permeable Barrier for Restriction of the Propagation of Lead and Nickel Ions in Groundwater by Ayad A. H. Faisal, Zaid Abed Al-Ridah, Laith A. Naji, Mu. Naushad, Hamed A. El-Serehy

“…Outputs of flask and tank tests certified that this material could capture these ions with sorption efficiency greater than 95% at time, pH, sorbent dosage, and speed equal to 60 min, 4 for lead and 6 for nickel, 2.5 g/100 mL, and 250 rpm, respectively. …”
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Three-Dimensional Diffusion Model in Sports Dance Video Human Skeleton Detection and Extraction by Zhi Li

“…Among them, the feature detection description and model alignment of 3D nonrigid models are a fundamental problem with very important research value and significance and challenging at the same time, which has received wide attention from the academic community.…”
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Quantitative analysis of different SLAM algorithms for geo-monitoring in an underground test field by Jing Li, Jörg Benndorf, Paweł Trybała

“…Abstract Geo-monitoring provides quantitative and reliable information to identify hazards and adopt appropriate measures timely. However, this task inherently exposes monitoring staff to hazardous environments, especially in underground settings. …”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…Given the relevance of inflammatory reaction, anticytokines therapy, in particular the inhibition of interleukin 1 (IL-1), seems to be the most promising strategy. At the present time, intra-articular injection of IL-1 receptor antagonist is the only anticytokine approach that has been used in a human study of PTA. …”
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Condensed tannin from Caragana korshinskii extraction and protection effects on intestinal barrier function in mice by Xiaoyu Niu, Wei Qu, Zhiyu Chen, Hui Li, Peinan Liu, Mei Sun, Jing Yang, Yuanyuan Xing, Dabiao Li

“…The results show that the extraction conditions were as follows: extraction temperature was 52°C, extraction time was 95 min, liquid-solid ratio was 20:1 and acetone volume fraction was 62%. …”
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Differential proteome analysis of pea roots at the early stages of symbiosis with nodule bacteria by I. V. Leppyanen, A. N. Kirienko, A. A. Lobov, E. A. Dolgikh

“…To identify the proteins, a mass spectrometric analysis of tryptic peptides was performed on a quadrupole-time-of-flight mass spectrometer combined with a high-performance liquid chromatograph. …”
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Automated Bitcoin Trading dApp Using Price Prediction from a Deep Learning Model by Zhi Zhan Lua, Chee Kiat Seow, Raymond Ching Bon Chan, Yiyu Cai, Qi Cao

“…The integration of smart contracts and on-chain oracles ensures transparency and security, allowing real-time verification of portfolio management. The deployed cryptocurrency trading system performs these actions automatically without human intervention, which greatly reduces barriers to entry for ordinary users and investors. …”
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