Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Ca... by V. T. Ivashkin, I. V. Mayev, A. D. Kaprin, M. Yu. Agapov, D. N. Andreev, A. S. Vodoleev, M. Yu. Zharkova, M. P. Korolev, Yu. A. Kucheryavyi, T. L. Lapina, M. V. Mayevskaya, A. V. Okhlobystin, Ch. S. Pavlov, A. V. Paraskevova, S. S. Pirogov, E. A. Poluektova, D. E. Rumyantseva, A. S. Trukhmanov, P. V. Tsarkov, A. A. Sheptulin, O. S. Shifrin

“…The knowledge of clinical manifestations and risk factors in the development of digestive system neoplasms allows a physician to suspect cancer and devise a timely and adequate diagnostic strategy, including laboratory and instrumental studies at specialised clinical centres.…”
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Long-Term Follow-Up after Intravenous Immunoglobulin Therapy in Patients with Severe Ocular Mucous Membrane Pemphigoid Unresponsive to Conventional Therapy by Stefania Leuci, Massimo Amato, Elena Calabria, Raffaele Piscopo, Fausto Tranfa, Gianrico Spagnuolo, Michele Davide Mignogna

“…In conclusion, the IVIg has to be considered as a safe and successful alternative therapy in patients with severe ocular mucous membrane pemphigoid; furthermore, this kind of therapy seems to be effective in maintaining the clinical remission by the time.…”
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Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study by Fang Zhao, Yuan Wei, Yiming Yan, Han Liu, Sitong Zhou, Bo Ren, Ruijuan Liu

“…The method was validated and applied to a tissue distribution study of crizotinib in mice, which was reported for the first time. The results of the study showed that the main target organs of crizotinib were the lung, liver, and spleen, and a high concentration of crizotinib was found in the gastrointestinal tract. …”
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Developing an Optimal Antiviral Method for the Air-filtration System of Subway Stations by Dae Hoon Park, Jungho Hwang, Dongho Shin, Younghun Kim, Gunhee Lee, Inyong Park, Sang Bok Kim, Keejung Hong, Bangwoo Han

“…Furthermore, a theoretical analysis of the antiviral ability and antiviral effect regeneration for the case of dust loading was performed using a mathematical model to evaluate the time-dependent antiviral effect of the filter. Our model can be applied to the antiviral air-filtration system of subway stations to prevent the pandemic spread and predict the life cycle of antiviral filters.…”
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A combined recombinase polymerase amplification CRISPR/Cas12a assay for detection of Fusarium oxysporum f. sp. cubense tropical race 4 by Megan Ceris Matthews, Jos van der Linden, Isabelle Robène, Samuel Rozsasi, Beatrix Coetzee, Manuela Campa, Johan Burger, Uzoma Nobel Akwuruoha, Ndubuisi Johnkennedy Madufor, Willem Perold, Umezuruike Linus Opara, Altus Viljoen, Diane Mostert

“…The only management option available then is to replace Foc TR4-susceptible with -resistant varieties. Timely detection of the pathogen, however, is an important strategy to prevent the introduction of Foc TR4 into new areas and prevent its spread from infested sites. …”
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How Do Temporal and Geographical Kernels Differ in Reflecting Regional Disparities? Insights from a Case Study in China by Chunzhu Wei, Xufeng Liu, Wei Chen, Lupan Zhang, Ruixia Chao, Wei Wei

“…This study provides novel insights into the spatio-temporal determinants of regional economic disparities, offering a robust analytical framework for policymakers to address region-specific variables driving inequality over time and space. These insights contribute to the development of targeted and dynamic policies for promoting balanced and sustainable regional growth.…”
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Use of systemic therapies in adults with atopic dermatitis: 12-month results from the European prospective observational study in patients eligible for systemic therapy for atopic... by Marjolein de Bruin-Weller, Andrew E. Pink, Silvia M. Ferrucci, Annalisa Patrizi, Ake Svensson, Marie L. A. Schuttelaar, Marie Tauber, Marius Ardeleanu, Shyamalie Jayawardena, Moataz Daoud

“…Background The European Prospective Observational Study in Patients Eligible for Systemic Therapy for Atopic Dermatitis (EUROSTAD) is an ongoing observational study aiming to describe characteristics of patients with atopic dermatitis (AD) treated with systemic therapy over time and the management of their disease in a real-world setting.Methods Data from patients enrolled in EUROSTAD between March 2017 and April 2019 were analyzed for systemic therapy use and treatment change over 12 months.Results 288 patients reported taking systemic medications; 42.7% received cyclosporine, 35.3% dupilumab, 28.1% methotrexate, 25.4% oral corticosteroids, 6.8% azathioprine, 6.1% injectable corticosteroids, and 3.4% mycophenolate. …”
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Electrocatalytic and Photocatalytic N₂ Fixation Using Carbon Catalysts by Changchun Xu, Hongli Su, Shuaifei Zhao, Azadeh Nilghaz, Kunning Tang, Luxiang Ma, Zhuo Zou

“…While transition metal-based catalysts have solved the kinetic constraints to activate nitrogen bonds via the donation-back-π approach, there is a problem: the d-orbital electrons of these transition metal atoms tend to generate H-metal bonds, inadvertently amplifying unwanted HER. Because of this, a timely review of defective carbon-based electrocatalysts for NF is imperative. …”
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A Comparative Phytochemical Investigation of the Greek Members of the Genus <i>Helichrysum</i> Mill., with Emphasis on the Local Endemic <i>Helichrysum amorginum</i> Boiss and Orph by Iordanis Samanidis, Nikos Krigas, Vassilis Athanasiadis, Ioannis Makrygiannis, Martha Mantiniotou, Stavros I. Lalas

“…This study used liquid chromatography coupled with high-resolution mass spectrometry results to present the phytochemical composition of non-volatile secondary metabolites in 11 Greek <i>Helichrysum</i> taxa (species and subspecies). For the first time, their total polyphenol content is comparatively assessed and an overview of the non-volatile compounds for five Endangered or Critically Endangered Greek Endemic <i>Helichrysum</i> taxa are presented herein. …”
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Health status and living conditions of families ascribed to the Family Health Units by Tatiana de Oliveira Sato, Patricia Driusso, Regina Helena Vitale Torkomian Joaquim, Thelma Simões Matsukura, Marcia Regina Cangiani Fabbro, Ana Cláudia Garcia de Oliveira Duarte, Ana Silvia Moccellin, Tania de Fátima Salvini, Silvia Helena Zem-Mascarenhas

“…Interviews were conducted with the person responsible for the household present at the time of the survey. Data were entered into Epi Info and descriptively analyzed. …”
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Valorization of Date Pits as an Effective Biosorbent for Remazol Brilliant Blue Adsorption from Aqueous Solution by A. Thiam, K. Tanji, O. Assila, M. Zouheir, Redouane Haounati, A. Arrahli, A. Abeid, S. Lairini, R. Bouslamti, F. Zerouq, A. Kherbeche

“…The capacity of the adsorption has achieved 105 mg/g and a removal efficiency of 90.4% at 1.5 g/L RDP mass, 40 mg/L initial dye concentration, pH 2, temperature of 328 K, 40 µm particle size, and contact time of 50 min. The capacity of the adsorption could reach 198 mg/g by increasing the ionic strength of RBB solution. …”
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HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR Assay for Detecting High-Grade Cervical Lesion with Microscope Slides by Geehyuk Kim, Jemberu Taye, Kwangmin Yu, Sunyoung Park, Jungho Kim, Sunghyun Kim, Dongsup Lee, Hye-young Wang, Kwang Hwa Park, Hyeyoung Lee

“…However, it takes a long time to collect enough specimens to conduct statistical analysis. …”
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Efficient FPGA based architecture for high‐order FIR filtering using simultaneous DSP and LUT reduced utilization by Mountassar Maamoun, Adnane Hassani, Samir Dahmani, Hocine Ait Saadi, Ghania Zerari, Noureddine Chabini, Rachid Beguenane

“…Abstract This paper proposes an efficient high‐order finite impulse response (FIR) filter structure for field programmable gate array (FPGA)‐based applications with simultaneous digital signal processing (DSP) and look‐up‐table (LUT) reduced utilization. The real‐time updating of the filter coefficients is also put into perspective. …”
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Greening of Svalbard in the twentieth century driven by sea ice loss and glaciers retreat by Gianmarco Ingrosso, Chiara Ceccarelli, Federico Giglio, Patrizia Giordano, Jens Hefter, Leonardo Langone, Stefano Miserocchi, Gesine Mollenhauer, Alessio Nogarotto, Mathia Sabino, Tommaso Tesi

“…Analyses of satellite data (available since ~1980) have revealed a widespread tundra advance consistent with recent global warming, but the length is insufficient to resolve the long-term variability and the precise timing of the greening onset. Here, we measured plant-derived biomarkers from an Arctic fjord sediment core as proxies for reconstructing past changes in tundra vegetation during the transition from the Little Ice Age to modern warming. …”
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Adolescent mice exposed to TBI developed PD-like pathology in middle age by Rong Sha, Mingzhe Wu, Pengfei Wang, Ziyuan Chen, Wei Lei, Shimiao Wang, Shun Gong, Guobiao Liang, Rui Zhao, Yingqun Tao

“…PD-like behavioral dysfunction and pathological changes were aggravated with the injured time extension in chronic phase of TBI. The loss of tyrosine hydroxylase positive (TH+) neurons in the SN were partly associated with the accumulation of misfolded a-Synuclein and the cytoplasmic translocation of TDP-43 from nuclear. …”
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Long-Term Effects of Activity Status in the Elderly on Cardiorespiratory Capacity, Blood Pressure, Blood Lipids, and Body Composition: A Five-Year Follow-Up Study by Eli Carmeli, Pini Orbach, David T. Lowenthal, Joav Merrick, Raymond Coleman

“…It is generally recognized that physical activity levels in the elderly do not remain constant over time, and typically there is a marked reduction in physical activities in the elderly. …”
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Partly cloudy with a chance of mosquitoes: Developing a flexible approach to forecasting mosquito populations by Travis McDevitt‐Galles, Arthur T. Degaetano, Sarah C. Elmendorf, John R. Foster, Howard S. Ginsberg, Mevin B. Hooten, Shannon LaDeau, Katherine M. McClure, Sara Paull, Erin Posthumus, Ilia Rochlin, Daniel Grear

“…Abstract Climate‐induced shifts in mosquito phenology and population structure have important implications for the health of humans and wildlife. The timing and intensity of mosquito interactions with infected and susceptible hosts are a primary determinant of vector‐borne disease dynamics. …”
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Formation and Identification of Unresolved Complex Mixtures in Lacustrine Biodegraded Oil from Nanxiang Basin, China by Pengfei Guo, Sheng He, Shukui Zhu, Derong Chai, Shiyan Yin, Wei Dai, Wanfeng Zhang

“…A comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC × GC/TOFMS) method has been developed for the formation and identification of unresolved complex mixtures (UCMs) in lacustrine biodegraded oils that with the same source rock, similar maturity, and increasing degradation rank from Nanxiang Basin, China. …”
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Remote sensing applications for managing a large-scale restoration dynamics project throughout the City of Gold Coast conservation estate by Jean-Marc Hero, Luke Shoo, Michael Duncan, Darren Roche, Jesse Kenny, Howard Taylor, Tim Robson, Sanjeev Kumar Srivastava, Josh Veitch-Michaelis

“…The program is supported by an environmental decision support tool (oRestore) for the smart allocation of restoration funds over space and time (see [1] for details). We introduce the Restoration Dynamics Project, a quantitative evidence-based evaluation of the success of restoration actions undertaken between 2005 and 2022. …”
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The opposite effect of convulsant drugs on neuronal and endothelial nitric oxide synthase – A possible explanation for the dual proconvulsive/anticonvulsive action of nitric oxide... by Vega Rasgado Lourdes A., Ramón-Gallegos Eva, Rodríguez-Páez Lorena, Alcántara-Farfán Verónica

“…Their effects on NO levels in neurons and astrocytes depend on the concentration and time of treatment. These convulsant drugs caused an increase in nNO, but a decrease in eNO was proportional to the duration of treatment in both cases. …”
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