Ectopic ACTH Syndrome Emerging 5 Years after the Diagnosis of Neuroendocrine Tumor by Minghao Liu, Diane Hamele-Bena, John Ausiello, Gabrielle Page-Wilson

“…Retrospective examination of biopsy tissues showed rare ACTH immunoreactivity at the time of initial diagnosis, followed by staining in a greater proportion of cells as the disease progressed, consistent with EAS arising years after the diagnosis of NET. …”
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Identification of In Vivo Metabolites of Dictamnine in Mice Using HPLC-LTQ-Orbitrap Mass Spectrometry by Yudong Fu, Yujie Deng, Qing Yu, Xuxia Meng, Dabo Wang, Pei Wang, Ping Wang

“…The major metabolic pathways of DIC in animal and human liver microsomes were confirmed in the present study, including o-demethylation, monohydroxylation, N-oxidation, and 2,3-olefinic epoxidation pathways. For the first time, a mono-acetylcysteine conjugate of DIC (M9) was detected from DIC-treated mouse urine and plasma samples, and 4-methoxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (M10) and 2-(2,8-dihydroxy-4-methoxyquinolin-3-yl)acetaldehyde (M11) were identified as new metabolites of DIC; furthermore, using an in vitro human fecal incubation model, furo[2,3-b]quinolin-4-ol (M1) was verified to be a microbial demethylated metabolite of DIC. …”
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Nutrition before and during Surgery and the Inflammatory Response of the Heart: A Randomized Controlled Trial by Marlieke Visser, Hans W. M. Niessen, Wouter E. M. Kok, Riccardo Cocchieri, Willem Wisselink, Paul A. M. van Leeuwen, Bas A. J. M. de Mol

“…Major surgery induces a long fasting time and provokes an inflammatory response which increases the risk of infections. …”
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A Novel Approach to Cognitive Load Measurement in N-Back Tasks Using Wearable Sensors, Empirical Mode Decomposition With Machine Learning, and Explainable AI for Feature Importance by Aakanksha Dayal, Ziaullah Khan, Kiramat Ullah, Hee-Cheol Kim

“…Early detection of mental workload and stress is vital for preventing adverse health outcomes, emphasizing the importance of timely intervention. In this study, by applying Empirical Mode Decomposition (EMD) for feature extraction and machine learning classifiers, we achieved high performance with accuracy rates of 88.64% for ECG and 80.68% for Fingertip-PPG Signal. …”
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In Situ Growth of (−201) Fiber‐Textured β‐Ga2O3 Semiconductor Tape for Flexible Thin‐Film Transistor by Xiao Tang, Yue Zhao, Kuang‐Hui Li, Chen Liu, Hendrik Faber, Wedyan Babatain, Che‐Hao Liao, Saravanan Yuvaraja, Vishal Khandelwal, Dhanu Chettri, Haicheng Cao, Yi Lu, Chuanju Wang, Thomas D. Anthopoulos, Xixiang Zhang, Xiaohang Li

“…In the research, for the first time, Ga2O3 thin films are directly grown on SiOx/Al2Ox buffered Hastelloy substrates. …”
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Integrating Pull Request Comment Analysis and Developer Profiles for Expertise-Based Recommendations in Global Software Development by Sara Zamir, Abdul Rehman, Hufsa Mohsin, Elif Zamir, Assad Abbas, Fuad A. M. Al-Yarimi

“…This research provides a significant achievement of recommendation systems in the global software development context that support more effective collaboration and increase the probability of project completion on time by allowing project managers to find easily accessible developers in the field with the right expertise.…”
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Analytical Differentiation of Wines from Three Terroirs Located in a Warm Winegrowing Area Based on Their Volatilome by José Miguel Fuentes-Espinosa, Raquel Muñoz-Castells, Jaime Moreno-García, Teresa García-Martínez, Juan Carlos Mauricio, Juan Moreno

“…This research aims to identify aroma compounds, their combinations, and statistical relationships to classify and characterize wines produced in small, defined areas known as “terroirs”, which share edaphoclimatic characteristics grape varieties, viticultural practices, harvest timing, and winemaking processes. The goal is to deepen the understanding of the relationship between the terroir and wine typicity. …”
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Reduced contrast agent volume using a heart-rate dependent and free-breathing scanning protocol in coronary computed tomography angiography (CTA) for patients with chronic obstruct... by Zengkun Wang, Guoyue Chen, Dewei Song, Xiaodie Xu, Chu Chu, Shuning Zhang, Huijing Chai, Hairong Yu, Xiaomei Luan, Peiji Song

“…Group A (n = 200) underwent CTA following a traditional protocol (70mL). The timing of the scans in Group B (n = 200) was determined according to the patient’s HR and free-breathing (30mL). …”
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Global perspectives in acute and emergency general surgery in low and middle-income countries: a WSES project protocol for scoping review on global surgery by Mahmoud Diaa Hindawi, Arda Isik, Fausto Rosa, Diego Visconti, Taras Nechay, Sharfuddin Chowdhury, Abdourahmane Ndong, Tushar S. Mishra, Stefano Piero Bernardo Cioffi, Francesco Piscioneri, Edward C.T.H. Tan

“…Abstract Background Around five billion people globally lack access to safe, timely, and affordable surgical facilities and care in low-income and middle-income countries (LMICs). …”
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Disturbance Observer-Based Super-Twisting SMC for Variable Speed Wind Energy Conversion System Under Parametric Uncertainties by Ahmad Bala Alhassan, Muhammad Auwal Shehu, Vijayakumar Gali, Ton Duc do

“…However, the parameters of the wind energy conversion system (WECS)-based generators, including stator resistance and inductance, could change over time due to power loss, winding degradation, or core saturation. …”
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An atlas of neuropathic pain-associated molecular pathological characteristics in the mouse spinal cord by Fu-Lu Dong, Lina Yu, Pei-Da Feng, Jin-Xuan Ren, Xue-Hui Bai, Jia-Qi Lin, De-Li Cao, Yu-Tao Deng, Yan Zhang, Hui-Hui Shen, Hao Gong, Wen-Xing Sun, Dong-Qiu Chi, Yixiao Mei, Longfei Ma, Ming-Zhe Yin, Meng-Na Li, Peng-Fei Zhang, Nan Hu, Bing-Lin Zhou, Ying Liu, Xuan-Jie Zheng, Yi-Fan Chen, Da Zhong, Yuan-Xiang Tao, Min Yan, Bao-Chun Jiang

“…In addition, for the first time, we systematically exhibit “cross-talk omics” between the DRG neurons and SC dorsal horn neurons and glial cells, indicating an altered communication profile under NP conditions. …”
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Enhancing Physical Layer Security in WPCNs With IRS and Controlled Jamming for 6G IoT Applications by Iqra Hameed, Abid Afridi, Myung-Sun Baek, Hyoung-Kyu Song

“…Specifically, we jointly optimize the downlink/uplink time allocation, IRS phase shift matrices, and jamming interference to maximize the sum secrecy throughput. …”
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Targeted next-generation sequencing for antimicrobial resistance detection in ventilator-associated pneumonia by Yuting Li, Yanfang Jiang, Hao Liu, Yao Fu, Junying Lu, Hongyan Li, Lulu Sheng, Dejian Gu, Dong Zhang

“…Additionally, tNGS performed almost half the turnaround time of microbial culture (1.66 days vs 3.00 days). …”
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Liver Transplantation in Alcohol-Associated Hepatitis. Benefits and Limitations of Psychosocial Selection and Support in Alcohol Relapse. The Experience of a Tertiary Center in Ita... by Luca S. Belli, Adelaide Panariello, Giovanni Perricone, Paola Prandoni, Raffaella Viganò, Chiara Mazzarelli, Chiara Becchetti, Sara Giacalone, Giovanna Donvito, Sara Conti, Paolo A. Cortesi, Elena Roselli, Gianpaola Monti, Marco Carbone, Luciano G. De Carlis, Luciano G. De Carlis, Mauro Percudani

“…Thirty (30%) were listed, of whom 25 underwent early liver transplantation (eLT) after a median time of 36 days from the index episode of SAH with a median model for end stage liver disease (MELD) score of 36, whereas 33 (33%) were excluded, with psycho-social issues being the main cause of exclusion in 18 patients (54.5%). …”
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Optimal selection of machine learning algorithms for ciprofloxacin prediction based on conventional water quality indicators by Shenqiong Jiang, Xiangju Cheng, Baoshan Shi, Dantong Zhu, Jun Xie, Zhihong Zhou

“…Techniques for determining antibiotics are often time-consuming, labor-intensive and costly, and it is desirable to seek new methods to achieve rapid prediction of antibiotics. …”
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East Asian Gene flow bridged by northern coastal populations over past 6000 years by Juncen Liu, Yichen Liu, Yongsheng Zhao, Chao Zhu, Tianyi Wang, Wen Zeng, Bo Sun, Fen Wang, Hui Han, Zhenguang Li, Xiaotian Feng, Peng Cao, Fengshi Luan, Feng Liu, Qingyan Dai, Junfeng Guo, Zimeng Wang, Chengmin Wei, Qiaowei Wei, Ruowei Yang, Weihong Hou, Wanjing Ping, Fan Bai, Bo Miao, Wenjun Wang, Melinda A. Yang, Qiaomei Fu

“…To examine how ShanDong populations changed over time and interacted with island and inland East Asian populations, we sequenced 85 individuals from 11 ancient sites in the ShanDong region dating to ~6000-1500 BP. …”
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A multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research by Christian M. Beusch, Ken Braesch-Andersen, Ulrika Felldin, Pierre Sabatier, Anna Widgren, Jonas Bergquist, Karl-Henrik Grinnemo, Sergey Rodin

“…Here, we have revisited published data and conducted a clinically relevant time-course experiment in mice, revealing organ-specific proteome regulation after death, with only a fraction of these changes linked to protein autolysis. …”
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Striatal Injury with 6-OHDA Transiently Increases Cerebrospinal GFAP and S100B by Cristiane Batassini, Núbia Broetto, Lucas Silva Tortorelli, Milene Borsoi, Caroline Zanotto, Fabiana Galland, Tadeu Mello Souza, Marina Concli Leite, Carlos-Alberto Gonçalves

“…Both glial fibrillary acidic protein (GFAP) and S100B have been used as markers of astroglial plasticity, particularly in brain injury; however, they do not necessarily change in the same time frame or direction. Herein, we induced a Parkinson’s disease (PD) model via a 6-OHDA intrastriatal injection in rats and investigated the changes in GFAP and S100B using ELISA in the substantia nigra (SN), striatum, and cerebrospinal fluid on the 1st, 7th, and 21st days following the injection. …”
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PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response by Ling Cheng, Ian Meliala, Yidi Kong, Jingyuan Chen, Christopher G Proud, Mikael Björklund

“…Consistently, overexpression of PEBP1 potentiated ISR activation by heme-regulated inhibitor (HRI) kinase, the principal eIF2α kinase in the mitochondrial ISR pathway. Real-time interaction analysis using luminescence complementation in live cells revealed an interaction between PEBP1 and eIF2α, which was disrupted by eIF2α S51 phosphorylation. …”
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Cellular Response to a Novel Fetal Acellular Collagen Matrix: Implications for Tissue Regeneration by Robert C. Rennert, Michael Sorkin, Ravi K. Garg, Michael Januszyk, Geoffrey C. Gurtner

“…Implant site tissue was harvested for histology, immunohistochemistry (IHC), and flow cytometric analyses at multiple time points until day 28. Results. PriMatrix implants were found to go through a biological progression initiated by a transient infiltrate of inflammatory cells, followed by mesenchymal cell recruitment and vascular development. …”
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