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53441
Repetitive Transcranial Magnetic Stimulation of Dorsolateral Prefrontal Cortex Affects Performance of the Wisconsin Card Sorting Task during Provision of Feedback
Published 2008-01-01“…We applied rTMS to the right DL-PFC and the vertex (control site) in different time points of the WCST. When rTMS was applied to the DL-PFC specifically during the period when subjects were receiving feedback regarding their previous response, WCST performance deteriorated, while rTMS did not affect performance during matching either when maintaining set or during set-shifting. …”
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53442
Physics-Based SPICE-Compatible Compact Model of FLASH Memory With Poly-Si Channel for Computing-in-Memory Applications
Published 2025-01-01“…The model was also validated against the results obtained from the TCAD tool, showing that a consistent VT change was computed in a shorter time than that required using TCAD. Then, the developed model was used to comprehensively investigate how single or multiple gate voltage (VG) pulses affect VT. …”
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53443
Graft success and seedling growth responses of cashew (Anacardium occidentalis) to three concentrations of Indole Butyric Acid (IBA) and scion types
Published 2024-12-01“…Seed propagation is a major problem because it takes the crop a much longer time to reach edible maturity compared to vegetative propagation. …”
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53444
Structural and functional analysis reveals the catalytic mechanism and substrate binding mode of the broad-spectrum endolysin Ply2741
Published 2025-12-01“…To the best of our knowledge, we found that residue Gln29 participated in the lytic activity of endolysin for the first time. Additionally, we systematically elucidate the binding mode and key residues of the Ply2741CBD. …”
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53445
Sensitivity Analysis and Numerical Simulation Study on Main Controlling Factors of Surface Movement and Deformation in Strip Filling Mining under Thick Unconsolidated Layers
Published 2021-01-01“…The development of strip filling technology provides a kind of economical and effective surface subsidence control technology. With the passage of time, the natural weathering, flow, and fracture of some coal pillars may lead to the instability and failure of some coal pillars. …”
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53446
Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells
Published 2019-01-01“…Our findings demonstrate for the first time that hydrazone M1 is capable of promoting cardiac differentiation of human iPSCs, highlighting the important role of mitochondrial dynamics in cardiac mesoderm lineage specification and cardiac development. …”
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53447
A Stability-Indicating HPLC-DAD Method for Determination of Stiripentol: Development, Validation, Kinetics, Structure Elucidation and Application to Commercial Dosage Form
Published 2014-01-01“…Stiripentol degraded only under acidic conditions, forming a single degradation product which was well resolved from the pure drug with significantly different retention time values. This degradation product was characterized by 1H-NMR and 13C-NMR spectroscopy as well as ion trap mass spectrometry. …”
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53448
Antiedemic Effect of the Myosin Light Chain Kinase Inhibitor PIK7 in the Rat Model of Myocardial Ischemia Reperfusion Injury
Published 2025-01-01“…The early no-reflow detected for the first time after 30 min ischemia in this model of myocardial infarction reduces the area accessible for PIK7. …”
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53449
Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus
Published 2025-01-01“…Because of its structural difference from natural GLP-1, it is not easy to be degraded by dipeptidyl peptidase-4 (DPP-4), thus prolonging the action time. GLP-1RAs have been recognized as a new type of hypoglycemic drugs and widely used in the treatment of type 2 diabetes mellitus (T2DM). …”
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53450
A Comparative Study of Advanced Oxidation Processes for the Removal of the Antibiotic Sulfadoxine from Water—Transformation Products and Toxicity
Published 2025-01-01“…High-Resolution Mass Spectrometry identified 11 SDX transformation products formed during photocatalysis, with their formation mechanisms reported for the first time. An ecotoxicity assessment using ECOSAR software revealed insights into the potential environmental impact of these by-products.…”
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53451
Optimized Application of CGA-SVM in Tight Reservoir Horizontal Well Production Prediction
Published 2025-01-01“…In this paper, chaotic genetic algorithm is used to optimize the traditional support vector machine, and the problems of slow convergence and local convergence are solved by chaotic genetic algorithm, and an improved support vector machine horizontal well production prediction method is established. At the same time, on the basis of the previous data processing, the fuzzy set classification method is used to build the model, and the learning model is more close to different types of well production, which enhances the applicability of the model in the field practice. …”
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53452
Prediction of Dynamic Plasmapause Location Using a Neural Network
Published 2021-05-01“…Our model can also produce a smooth magnetic local time variation of the plasmapause location with good accuracy, which can be incorporated into global radiation belt simulations and space weather forecasts under a variety of geomagnetic conditions.…”
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53453
A Binational Sample-Initiated Retrospective Outbreak Investigation of Listeria monocytogenes Infections in the United States and Canada Linked to Enoki Mushrooms Imported from Chin...
Published 2025-01-01“…The FDA and CDC investigated the first known L. monocytogenes outbreak linked to enoki mushrooms from 2016 to 2020, making the 2022 outbreak the second time this pathogen-commodity pair was investigated by FDA and CDC. …”
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53454
Targeted co-delivery nanosystem based on methotrexate, curcumin, and PAMAM dendrimer for improvement of the therapeutic efficacy in cervical cancer
Published 2025-01-01“…The cumulative in vitro release of Cur-loaded NC indicated a controlled release influenced by time and pH. The cell study results revealed that Cur-PAMAM-MTX NC exhibited significantly higher cytotoxicity than free MTX, Cur, and other formulations tested in vitro. …”
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53455
Effects of different wet distillers’ grains ratios on fermentation quality, nitrogen fractions and bacterial communities of total mixed ration silage
Published 2025-01-01“…Conclusion The fermentation quality of TMR silage is always decreasing during storage, so its storage time should be minimized. Incorporating 30% WDG reduced abundance of Weissella, resulting in less protein degradation and better fermentation quality in TMR silage.…”
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53456
A Cocktail Method for Promoting Cardiomyocyte Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells
Published 2014-01-01“…Immunofluorescence results showed that cTnT expression in the 5-aza+salB+CLM group was stronger than other groups. Real-time qPCR and Western blotting analyses showed that cTnT, alpha-cardiac actin, mef-2c, Cx43, and GSK-3beta expression increased while beta-catenin expression decreased. …”
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53457
The Effect of Frailty on Balance, Fear of Falling, and Dual-Task Performance in Individuals with Type 2 DM
Published 2024-12-01“…The FRAIL Scale evaluated individuals’ frailty levels, Timed Up and Go Test evaluated dual-task performance (cognitive and motor), and Tinetti Balance and Gait Scale evaluated balance and risk of falls. …”
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53458
Post-COVID-19 resurgence of scabies’ cases in the Lazio Region, Italy: a new emerging public health threat?
Published 2025-02-01“…Consistently, the number of scabies outbreaks, after a decrease following the first COVID-19 wave, has progressively increased over time, mainly due to the occurrence of outbreaks in long term facilities (750% from 2020 to 2023). …”
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53459
Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway
Published 2014-01-01“…These data suggest for the first time that niacin inhibits vascular inflammation in vivo and in vitro via downregulating NF-κB signaling pathway. …”
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53460
Intraperitoneal fipronil effects on liver histopathological, biochemistry and morphology in Caspian kutum, Rutilus frisii kutum (Kamenskii, 1901)
Published 2017-12-01“…Pyknosis, sinusoid dilation and vacuolization were common histological changes, and these changes became more severe in a time and dose dependent manner. This dependence was also observed for HSI and the liver biochemical test (alanine and aspartate transaminase). …”
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