The microenvironment cell index is a novel indicator for the prognosis and therapeutic regimen selection of cancers by Xian-Yan Yang, Nian Chen, Qian Wen, Yu Zhou, Tao Zhang, Ji Zhou, Cheng-Hui Liang, Li-Ping Han, Xiao-Ya Wang, Qing-Mei Kang, Xiao-Xia Zheng, Xue-Jia Zhai, Hong-Ying Jiang, Tian-Hua Shen, Jin-Wei Xiao, Yu-Xin Zou, Yun Deng, Shuang Lin, Jiang-Jie Duan, Jun Wang, Shi-Cang Yu

“…More importantly, inhibition of the insulin signaling pathway activated in the cancer cells of the MCIhigh the TNBC patients significantly prolonged the survival time of tumor-bearing mice. Conclusions Overall, our results demonstrate that MCs infiltration can be exploited as a novel indicator for the prognosis and therapeutic regimen selection of the TNBC patients.…”
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Simplified Physical Stability Assessment of Chilean Mine Waste Storage Facilities Using GIS and AI: Application in the Antofagasta Region by Gabriel Hermosilla, Gabriel Villavicencio, Giovanni Cocca-Guardia, Vicente Aprigliano, Manuel Silva, Juan Carlos Quezada, Pierre Breul, Vinicius Minatogawa, Jaime Morales

“…This approach reduces analysis time and minimizes human error. Validated in the Antofagasta Region, Chile’s primary mining area, we identified and evaluated 70 WRD and 54 LWD. …”
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Rolling Bearing Fault Diagnosis Based on Domain Adaptation and Preferred Feature Selection under Variable Working Conditions by Xiao Yu, Wei Chen, Chuanlong Wu, Enjie Ding, Yuanyuan Tian, Haiwei Zuo, Fei Dong

“…In this framework, an improved domain adaptation method, transfer component analysis with preserving local manifold structure (TCAPLMS), is proposed to reduce the differences in the data distributions between different domain datasets and, at the same time, take the label information of feature dataset and the local manifold structure of feature data into consideration. …”
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Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats by Maria Rosana Ramirez, Debora Manuale, Juan Carlos Yori

“…Blood samples were collected at the time of sacrifice. The weights of heart, liver, kidneys and spleen of the experimental rats with respect to body weight were recorded. …”
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Diagnosis of Sleep Apnea Hypopnea Syndrome Using Fusion of Micro-motion Signals from Millimeter-wave Radar and Pulse Wave Data by Xiang ZHAO, Wei WANG, Chenyang LI, Jian GUAN, Gang LI

“…This study used a radar and pulse wave data preprocessing algorithm to extract time-frequency information and artificial features from the signals, balancing the accuracy and robustness of sleep-breathing abnormality event detection Additionally, a deep neural network was designed to fuse the two types of signals for precise identification of sleep apnea and hypopnea events, and to estimate the Apnea-Hypopnea Index (AHI) for quantitative assessment of sleep-breathing abnormality severity. …”
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An Unsuspected Finding of t(9;22): A Rare Case of Philadelphia Chromosome-Positive B-Lymphoblastic Lymphoma by Prajwal Boddu, C. Cameron Yin, Rashmi Kanagal-Shamanna, Guillin Tang, Beenu Thakral, Tapan Kadia, Marina Konopleva, Elias Jabbour, Nitin Jain

“…The initial plan of treatment was to treat along the lines of Philadelphia negative B-ALL/LBL. During this time, fluorescence in situ hybridization (FISH) and PCR testing for BCR-ABL1 rearrangements were being performed on the marrow specimens as a part of routine diagnostic workup. …”
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Assessment of Water Surface Reflectance and Optical Water Types Over Two Decades in Europe's Largest Artificial Lake: An Intercomparison of ESA and NASA Satellite Data by Goncalo Rodrigues, Miguel Potes, Maria Joao Costa

“…Using 300 or 1000 m of spatial resolution, the Alqueva reservoir mostly exhibits high water transparency, associated with low surface reflectances for the majority of the time. Seasonal analysis revealed periods with the presence of microalgae in summer and autumn (SON), with a noticeable increase in the intensity and duration of these blooms in the SON period over the last ten years. …”
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From Guidelines to Action: Tackling Risk Factors for Surgical Site Infections by Caterina Elisabetta Rizzo, Roberto Venuto, Paola Tripodi, Linda Bartucciotto, Elvira Ventura Spagnolo, Antonio Nirta, Giovanni Genovese, Isabella La Spina, Sabrina Sortino, Alessandro Nicita, Francesco Loddo, Bruno Romeo, Raffaele Squeri, Cristina Genovese

“…The most administered antibiotic was cefazolin, and antibiotic administration time was in compliance with the guidelines. <b>Conclusions:</b> Our data show that the implementation of evidence-based guidelines, healthcare professionals’ education and correct antibiotic use can reduce the burden of SSIs by improving patient care.…”
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Polymorphisms of Tumor Necrosis Factor Alpha in Moroccan Patients with Gastric Pathology: New Single-Nucleotide Polymorphisms in TNF-α−193 (G/A) by A. Essadik, H. Jouhadi, T. Rhouda, S. Nadifiyine, A. Kettani, F. Maachi

“…However, all these studies are conducted in Caucasian and Asian populations. Thus, for the first time in Africa, we sought to investigate whether polymorphisms in TNF-α gene were associated with the development of gastric pathology in Morocco. …”
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All‐Inorganic Perovskite Quantum‐Dot Optical Neuromorphic Synapses for Near‐Sensor Colored Image Recognition by Yung‐Chi Yao, Chia‐Jung Lee, Yong‐Jun Chen, Jun‐Zhi Feng, Hongseok Oh, Chin‐Shan Lue, Jinn‐Kong Sheu, Ya‐Ju Lee

“…Additionally, the seamless integration of electronics and photonics within a unified material system establishes a novel paradigm for optical retrieval, enabling real‐time perception of the encoded status of the ONS device. …”
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Stable Field Emissions from Zirconium Carbide Nanoneedle Electron Source by Yimeng Wu, Jie Tang, Shuai Tang, You-Hu Chen, Ta-Wei Chiu, Masaki Takeguchi, Ayako Hashimoto, Lu-Chang Qin

“…Benefiting from controlled fabrication with real-time observation, the ZrC nanoneedle has a smooth surface and a tip with a radius of curvature smaller than 20 nm and a length greater than 2 μm. …”
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IUGR Management: New Perspectives by N. Giuliano, M. L. Annunziata, S. Tagliaferri, F. G. Esposito, O. C. M. Imperato, M. Campanile, M. G. Signorini, A. Di Lieto

“…The patients were divided into three groups according to the age of gestation at the time of delivery, before the 34th week, from 34th to 37th week, and after the 37th week. …”
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Systematic Search for Long-term Trends in Fermi-LAT Jetted Active Galactic Nuclei by P. Peñil, A. Domínguez, S. Buson, M. Ajello, S. Adhikari, A. Rico

“…Additionally, a novel type of variability has emerged in jetted AGN light curves, specifically, the observation of a long-term trend characterized by a linear increase of the flux with time in blazars such as PG 1553+113, which is among the objects most likely to display periodic behavior. …”
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Choriocarcinoma Syndrome as an Initial Presentation of Testicular Cancer by Carlos Eduardo Salazar-Mejía, María Elena García-Gutiérrez, María Inés Contreras-Salcido, Carlos Javier Rodríguez-Álvarez, Blanca Otilia Wimer-Castillo, Jackeline Grace Lara-Campos, Edio Llerena-Hernández, José Luis González-Vela, David Hernández-Barajas

“…Due to the severity of the presentation, hemodynamic monitoring, ideally in an intensive care unit, is essential as well as timely administration of cytotoxic treatment.…”
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Case Report: Respiratory outcome in a preterm infant following previable rupture of membranes and persistent oligohydramnios by Akila Subramanian, Ong Kai Zhi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Lay Kok Tan, Suresh Chandran, Suresh Chandran, Suresh Chandran, Suresh Chandran

“…In this reported case, we highlight the importance of multidisciplinary and interprofessional team management from antepartum monitoring and planning delivery time to subsequent short- and long-term postnatal care involving maternal-fetal medicine specialists, neonatologists, pediatric cardiology and respiratory specialists, and home care teams.…”
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Genotype B of deformed wing virus and related recombinant viruses become dominant in European honey bee colonies by Fabrice Sircoulomb, Eric Dubois, Frank Schurr, Pierrick Lucas, Marina Meixner, Alicia Bertolotti, Yannick Blanchard, Richard Thiéry

“…In this study, we quantified both DWV genotypes by real-time PCR from pools or individual honey bees and from V. destructor mites sampled in 15 European countries between 2010 and 2017. …”
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Parboiled rice supplementation alleviates high-fat diet-induced hyperlipidemia by regulating genes and gut microbiota in mice by Xiuxiu Wu, Tianyi Guo, Biao Li, Shuai Han, Zuomin Hu, Yi Luo, Dandan Qin, Yaping Zhou, Feijun Luo, Qinlu Lin

“…And 15 differentially expressed genes (DEGs) were validated by quantitative real-time PCR (RT-qPCR), while protein interaction network showed that protein tyrosine phosphatase receptor type C (PTPRC) has a central role. …”
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Metabolic Activity of Micromycetes Affecting Urban Concrete Constructions by Galina Yakovleva, Eugene Sagadeev, Viktor Stroganov, Olga Kozlova, Rodion Okunev, Olga Ilinskaya

“…The alterations in concrete resistances to compression and flexure after fungal attack were recorded at the trend level, mainly due to a short exposure time of concrete to fungal destructors in tests recommended by national Russian standard. …”
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Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge by Francesco Guido Mangano, Piero Antonio Zecca, Ric van Noort, Samvel Apresyan, Giovanna Iezzi, Adriano Piattelli, Aldo Macchi, Carlo Mangano

“…The scaffold closely matched the shape of the defect: this helped to reduce the time for the surgery and contributed to good healing. …”
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Smad2/3 Upregulates the Expression of Vimentin and Affects Its Distribution in DBP-Exposed Sertoli Cells by Xi Zhang, Xiaogang Wang, Taixiu Liu, Min Mo, Lin Ao, Jinyi Liu, Jia Cao, Zhihong Cui

“…We hypothesized that Smad2/3 affects the distribution of vimentin by regulating its expression and that there is cross talk between Smad2/3 and PPARα. The real-time PCR and ChIP-qPCR results showed that SB431542 (an inhibitor of Smad2/3) could significantly attenuate the expression of vimentin induced by DBP in SCs. …”
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