Role of CTCF protein in regulating FMR1 locus transcription. by Stella Lanni, Martina Goracci, Loredana Borrelli, Giorgia Mancano, Pietro Chiurazzi, Umberto Moscato, Fabrizio Ferrè, Manuela Helmer-Citterich, Elisabetta Tabolacci, Giovanni Neri

“…Here we demonstrate for the first time that rare unmethylated full mutation (UFM) alleles present the same boundary described in wild type (WT) alleles and that CTCF binds to this region, as well as to the FMR1 gene promoter, exon 1 and intron 2 binding sites. …”
Get full text

Urban Scenic Spot Activity Center Investment: Strategic Construction Company Selection Using the Grey System-II Thinking Compromise Ranking of Alternatives from Distance to Ideal S... by Shuo Zhang, Moses Olabhele Esangbedo

“…We address the intricacies of contractor selection by integrating MCDM and system thinking approaches, emphasizing the alignment of investment strategies with broader urban development goals. First, a time delay was introduced between the first and second rounds of administering the weighting questionnaire to capture decision-makers’ preferences for the evaluation criteria as System-2 thinking, then the Grey System-2 Thinking (GS2T) weighting method was proposed for group decision-making. …”
Get full text

Hematological Factors and MRI in Covid-19 Infected may Predict the Prevalence of Multiple Sclerosis in the Post-Covid era by Bakhtiar Ebrahimirad, Mahnaz Taherianfard, Arash Mosarezaii

“…Materials and Methods In this cross-sectional observational study, 80 human samples were selected from 20-50-year-olds infected with COVID-19 based on PCR tests at the time of infection from February 11th, 2020 to November 20th, 2021. …”
Get full text

Solubility of gemcitabine (an anticancer drug) in supercritical carbon dioxide green solvent: Experimental measurement and thermodynamic modeling by Gholamhossein Sodeifian, Masturah Markom, Jarinah Mohd Ali, Muhammad Zulhaziman Mat Salleh, Reza Derakhsheshpour

“…The solubility of gemcitabine in SC-CO2 using a static method at temperatures of 308–338 K and pressures of 120–270 bar were measured and modeled for the first time. Solubility of gemcitabine ranged from 0.1274 × 10− 5 to 1.8128 × 10− 5 in mole fraction and 0.00295 to 0.08489 kg/L. …”
Get full text

Marine Automatic Weather System (MAWS) instrumentation system for climate change monitoring based on The Internet of Things (IoT) by Husen Zakaria, Ismail Nazli, Syukri Surbakti Muhammad, Omar Fairuz, Yusibani Elin, Kesuma Fatmawati, Nurhanif Nurhanif, Arif Hasibuan Ahmad, Fauzi Fauzi

“…In this research, there are two stages of equipment testing, i.e. laboratory testing to determine whether data can be sent in real-time into the database, and field testing which functions to calibrate the equipment. …”
Get full text

The Translation of Ὑποκριτης in the Gospels as Osatotsε in Dangme Bible Translations by Ebenezer Quaye, Jonathan Edward Tetteh Kuwornu-Adjaottor

“…Words, phrases and other expressions are socio-culturally or contextually defined and more so, they assume new meanings through both diachronic and synchronic time effects. The nuances in meaning when ideas are carried from one linguistic setting to another is another challenge in translation work. …”
Get full text

Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum by Ming Cong, Zhaoshun Li, Wenwen Tian, Yixian Yu, Yu Che, Jiasen Lv

“…Overall, this study revealed for the first time the regulatory effects of miRNA-375 in the clams and gave valuable clues to understand the toxicological mechanisms of ammonia nitrogen on the marine bivalve.…”
Get full text

Changes in Texture and Flavor of Dehydrated Shiitake Mushroom during Rehydration by LI Qianyu, CAO Xuehui, ZHUO Qiuchen, YOU Kaiyan, LIANG Zhitang, ZHU Danshi

“…The results showed that both rehydration temperature and time had significant effects on the texture, volatile flavor and taste of rehydrated mushroom. …”
Get full text

Close to the border-Resilience in healthcare in a European border region: Findings of a needs analysis. by Leonie A K Loeffler, Sophie Isabelle Lambert, Lea Bouché, Martin Klasen, Saša Sopka, Lina Vogt, COMPAS Consortium

“…Most challenging stressors were staff availability, available time, and workload. On average, individual resilience was in the normal range, yet 15.6% showed below average resilience. …”
Get full text

Characterising educational research on climate change in the climate emergency era (2017–2024) by Marta Segade Vázquez, Antonio García Vinuesa, Ana Rodríguez Groba, Júlio J. Conde

“…Seven years on, with more than 2300 climate emergency declarations having been issued by jurisdictions representing over one billion people, it seems timely to update the characterisation of this field. …”
Get full text

Corticolimbic circuitry as a druggable target in schizophrenia spectrum disorders: a narrative review by Abigail Gee, Paola Dazzan, Anthony A. Grace, Gemma Modinos

“…Translation of these findings into clinical practice will be aided by consideration of optimal intervention timings, biomarker-led patient stratification, and the development of more selective medications.…”
Get full text

Incidence of Post Instrumentation Pain Following Endodontic Treatment Among Patients Attending College of Dentistry-Hawler Medical University. by Intesar Saadallah Toma, Hussein Jamal Hashim, Muhammed Amir Salahadin, Muhammed Dana Razaq

“…Method: A total of fifty-two patients were considered participants and were included for history taking, clinical examination, radiographic assessment, and data analysis after receiving Root Canal Treatment (RCT) for different types of teeth (incisors, canine, and premolar) by different students (operators) and different supervising seniors (trainers). During this time, the operator performed RCT on various patients, and the participants were followed up after they completed root canal obturation. …”
Get full text

Forecasting Ionospheric foF2 Using Bidirectional LSTM and Attention Mechanism by Jun Tang, Dengpan Yang, Mingfei Ding

“…The inputs of models are the foF2 of globally available ionospheric ionosonde stations, geographic longitude and latitude, world time (UT), geomagnetic activity index, and solar activity index from 2015 to 2017. …”
Get full text

Analysis of Transformer Insulation Risk Due to Back Flashover Lightning on High Voltage Substations by Considering the Effect of Environmental Pollution by Faridoddin Safaei, Mohsen Niasati

“…Therefore, the voltage-time-dependent strength accumulation characteristic has been developed in this study based on the transformer's non-self-healing behavior when exposed to various insulation stresses. …”
Get full text

TEC Map Completion Using DCGAN and Poisson Blending by Yang Pan, Mingwu Jin, Shunrong Zhang, Yue Deng

“…The processing to obtain complete TEC maps is time consuming and needs the collaboration of five international GNSS service (IGS) centers to consolidate final completed IGS TEC maps. …”
Get full text

Perspectives of pressurized intraperitoneal aerosol chemotherapy in terms of primary ovarian cancer with peritoneal carcinomatosis treatment by A. S. Dzasokhov, A. A. Kostin, V. L. Astashov, A. V. Turiev, A. D. Uskov

“…The standard modern approach to the treatment of ovarian cancer is a combination of surgical treatment and systemic intravenous chemotherapy. At the same time, more than 70 % of ovarian cancer cases are first diagnosed at stages III–IV. …”
Get full text

Standardized Chromatographic and Computational Approaches for Lipophilicity Analysis of Five Gliflozin Antidiabetic Drugs in Relation to Their Biological Activity by Anna Gumieniczek, Anna Berecka-Rycerz, Marcelina Dul, Aleksandra Pryjda

“…This study represents the first-time experimental analysis of lipophilicity for antidiabetic drugs from the gliflozin class using chromatographic methods alongside computational approaches. …”
Get full text

THE PROBLEM OF SEARCHING THE MEANING OF HUMAN EXISTENCE: CONTEMPORARY CONTEXT by V. M. Petrushov, V. M. Shapoval

“…Originality lies in the fact that this article is the first attempt to conduct comprehensive analysis in the problem of the sense of the Existence as it is presented in the first quarter of the 21st century and to relate it with the modern social situation that is characterized by a complex range of interconnected and interdependent anthropological problems of our time. Authors emphasize that the main reason in the crisis of meaning is that a man has lost touch with his roots, which is wildlife. …”
Get full text

Adsorption of Cu(II) Ions onto a Cellulosic Biosorbent, Leaf Powder: Application in Water Treatment by Krishna Gopal Bhattacharyya, Arunima Sarma, Jyotirekha Sarma

“…The powdered biomass was investigated as a sorbent for Cu(II) ions employing pH, time, initial Cu(II) ion concentration and the amount of sorbent as the experimental variables. …”
Get full text

Breeding and selection of mini-pigs in the ICG SB RAS by S. V. Nikitin, S. P. Knyazev, K. S. Shatokhin, V. I. Zaporozhets, V. I. Ermolaev

“…It turned out that effective evaluation of the genetic potential of mini-pigs in growth rate and fnal size of individuals is only possible under the condition of a rich and full feeding of young animals. The time scale of estimation of growth of live weight of the ICG mini-pigs for three weight categories allocated in the selection group is presented. …”
Get full text