Optimization Studies on the Extraction of Flavone Di-C-glycosides from Premna fulva Craib by Deep Eutectic Solvents by Yueyuan Chen, Jiaoyang Dang, Xiaojie Yan, Fenglai Lu, Dianpeng Li

“…Subsequently, the extraction parameters for ultrasonic-assisted extraction (liquid-solid ratio, water content (%) in the selected DES, and extraction time) were optimized using response surface methodology. …”
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NEMS generated electromechanical frequency combs by Sasan Rahmanian, Hamza Mouharrar, Rana Abdelrahman, Masoud Akbari, Yasser S. Shama, Kevin Musselman, David Muñoz-Rojas, Skandar Basrour, Eihab Abdel Rahman

“…The superior phase coherence of the FC generated via the 2:1 modal interaction was demonstrated via time-domain analysis. Our technique has the flexibility to generate multiple frequency combs and to fine-tune their FSR depending on the number of mechanical modes accessible to and the order of the activated modal interaction. …”
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Supercritical Fluid Chromatography of Drugs: Parallel Factor Analysis for Column Testing in a Wide Range of Operational Conditions by Ramia Z. Al Bakain, Yahya Al-Degs, Bertyl Andri, Didier Thiébaut, Jérôme Vial, Isabelle Rivals

“…Retention mechanisms involved in supercritical fluid chromatography (SFC) are influenced by interdependent parameters (temperature, pressure, chemistry of the mobile phase, and nature of the stationary phase), a complexity which makes the selection of a proper stationary phase for a given separation a challenging step. For the first time in SFC studies, Parallel Factor Analysis (PARAFAC) was employed to evaluate the chromatographic behavior of eight different stationary phases in a wide range of chromatographic conditions (temperature, pressure, and gradient elution composition). …”
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The disappearing COVID-Naïve Population and comparative Roche vs. Abbott Test sensitivity: evidence from antibody seroprevalence in Milwaukee County, Wisconsin by Lorenzo Franchi, Vladimir Atanasov, Mark Stake, Garrett Bates, Kristen Osinski, John R Meurer, Bernard Black

“…Nucleocapsid antibody tests, especially the Abbott test, were far less sensitive than spike protein tests, and Abbott test sensitivity faded with time since infection. Thus, studies which rely on nucleocapsid tests will understate prior infection rates. …”
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TGF-β1 Induces the Dual Regulation of Hepatic Progenitor Cells with Both Anti- and Proliver Fibrosis by Ai-Ting Yang, Dou-Dou Hu, Ping Wang, Min Cong, Tian-Hui Liu, Dong Zhang, Ya-Meng Sun, Wen-Shan Zhao, Ji-Dong Jia, Hong You

“…Consistent with these in vitro results, the in vivo fibrosis rat model showed the same time-dependent dual effect of TGF-β1. Regression of liver fibrosis as well as normalization of serum aminotransferase and albumin levels was detected in the rats transplanted with HPCs pretreated with TGF-β1 for 12 hours. …”
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Involuntary intoxication caused by vaping the synthetic cannabinoid ADB-BUTINACA: A case report by Elise M.A. Slob, Maryam Lyousoufi, Sharif Pasha, Erik B. Wilms

“…Despite all negative results in the point-of-care test for recreational drugs, the liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) analysis showed that the liquid of the e-cigarette contained ADB-BUTINACA, a synthetic cannabinoid. …”
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Efficacy of Memantine, Donepezil, or Their Association in Moderate-Severe Alzheimer’s Disease: A Review of Clinical Trials by Ivana Molino, Luisa Colucci, Angiola M. Fasanaro, Enea Traini, Francesco Amenta

“…The heterogeneity of conditions explored by RCTs, the relatively short time of observation (24–52 weeks), and the different cognitive assessment tools used did not allow comparing properly different trials.…”
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Predictive Modeling of Total Real and Reactive Power Losses in Contingency Systems Using Function-Fitting Neural Networks with Graphical User Interface by Alfredo Bonini Neto, Alexandre de Queiroz, Giovana Gonçalves da Silva, André Gifalli, André Nunes de Souza, Enio Garbelini

“…Additionally, a Graphical User Interface (GUI) was implemented to facilitate user interaction, allowing for easy visualization of power-loss predictions and real-time adjustments.…”
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Protective and immunomodulatory effects of the novel probiotic yeast Pichia kudriavzevii isolated from a home-made kefir during infection in human colon epithelial cells: An explor... by Angela Maione, Marianna Imparato, Annalisa Buonanno, Marilena Galdiero, Elisabetta de Alteriis, Marco Guida, Emilia Galdiero

“…Results showed that both live P. kudriavzevii and CFS-Y1 effectively decreased Salmonella spp. adhesion and invasion, in competition, inhibition and displacement assays, displaying the most potent inhibitory effects when Caco-2 cells were preincubated with Y1/ CFS-Y1 at different concentrations and then bacteria were added for an additional time. Furthermore, the treatment of LPS-induced Caco-2 cells with both Y1 and its CFS-Y1 effectively relieved the oxidative stress and improved the intestinal TJ barrier function. …”
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Peptide-Based Vaccinology: Experimental and Computational Approaches to Target Hypervariable Viruses through the Fine Characterization of Protective Epitopes Recognized by Monoclon... by Matteo Castelli, Francesca Cappelletti, Roberta Antonia Diotti, Giuseppe Sautto, Elena Criscuolo, Matteo Dal Peraro, Nicola Clementi

“…Experimental approaches aiming to characterize protective mAb epitopes or to identify T-cell-activating peptides are often burdened by technical limitations and can require long time to be correctly addressed. Thus, in the last decade many epitope predictive algorithms have been developed. …”
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Precision Imaging for Early Detection of Esophageal Cancer by Po-Chun Yang, Chien-Wei Huang, Riya Karmakar, Arvind Mukundan, Tsung-Hsien Chen, Chu-Kuang Chou, Kai-Yao Yang, Hsiang-Chen Wang

“…Early detection of early-stage esophageal cancer (ECA) is crucial for timely intervention and improved treatment outcomes. …”
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Magnetic beads as intravesical foreign bodies in children: our clinical experience by Yefeng Zeng, Shaogang Huang, Zhilin Yang, Xianbin Gu, Xuerui Sun, Pengyu Chen, Shoulin Li

“…Depending on the number of magnetic beads, their aggregation state, and the time since insertion, Three cases were successfully retrieved via cystoscopy, one via pneumovesicoscopy, and another via open surgery. …”
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Production of Biosurfactants by Soil Fungi Isolated from the Amazon Forest by Hellen Holanda Sena, Michele Alves Sanches, Diego Fernando Silva Rocha, Walter Oliva Pinto Filho Segundo, Érica Simplício de Souza, João Vicente Braga de Souza

“…In addition, the influences of bioprocess factors (carbon source, nitrogen source, pH, and fermentation time) were investigated. Finally, the biosurfactant produced was semipurified and submitted to stability tests. …”
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Modulation of behavior before COVID-19, in contact patients treated at the Villa Azucarera isolation center by Isela Casas Olazabal, Enia Lorenzo Pérez, Maria Cristina Pérez Guerrero, Jaqueline García Rodríguez, Ricardo Vázquez Casas

“…<br /><strong>Conclusions:</strong> The attitude of the patient during the surveillance in the institution changes from an explicit rejection at the beginning, to an acceptance at the time of discharge, and an increase in the perception of the risk of becoming ill due to the increase in the level of information and of the therapeutic relationship established with health personnel.…”
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Characterization of Manganese Oxide and the Adsorption of Copper(II) and Lead(II) Ions from Aqueous Solutions by Weihua Zou, Jinghua Zhang, Ke Li, Pan Han, Runping Han

“…Parameters affecting the adsorption of Cu(II) and Pb(II) ions, such as the adsorbent dosage, the ionic strength of the solution, the contact time, the solution pH, the initial metal ion concentration and the temperature, were investigated. …”
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Antiproliferative and genotoxic potential of xanthen-3-one derivatives by Veljović Elma, Špirtović-Halilović Selma, Muratović Samija, Osmanović Amar, Haverić Sanin, Haverić Anja, Hadžić Maida, Salihović Mirsada, Malenica Maja, Šapčanin Aida, Završnik Davorka

“…The most potent compounds were subjected to molecular docking simulations in order to analyse bindings to molecular targets and, at the same time, further support the results of experimental cytotoxic tests. …”
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Using Operational Analysis to Improve Access to Pulmonary Function Testing by Ada Ip, Raymond Asamoah-Barnieh, Diane P. Bischak, Warren J. Davidson, W. Ward Flemons, Sachin R. Pendharkar

“…Background. Timely pulmonary function testing is crucial to improving diagnosis and treatment of pulmonary diseases. …”
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A review on eye diseases induced by blue light: pathology, model, active ingredients and mechanisms by Yuan Yan, Yuan Yan, Yuan Yan, Yiyao Wu, Yiyao Wu, Yiyao Wu, Yu Zhao, Yu Zhao, Yu Zhao, Yaguang Yang, Yaguang Yang, Yaguang Yang, Guangtao An, Guangtao An, Guangtao An, Zhidong Liu, Zhidong Liu, Zhidong Liu, Zhidong Liu, Dongli Qi, Dongli Qi, Dongli Qi

“…Starting from the disease-related mechanisms and pathophysiological characteristics of eye blue light injury, this article elucidates the pharmacological mechanisms of various drugs for treating eye blue light injury. At the same time, it reviews the research on in vitro cultured cell and animal model conditions for blue light injury eyes, in order to provide reference for subsequent blue light injury modeling experiments. …”
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The Role of Atmospheric Composition in Defining the Habitable Zone Limits and Supporting <i>E. coli</i> Growth by Asena Kuzucan, Emeline Bolmont, Guillaume Chaverot, Jaqueline Quirino Ferreira, Bastiaan Willem Ibelings, Siddharth Bhatnagar, Daniel Frank McGinnis

“…By utilizing a 3D climate model, we refined the inner boundaries of the HZ for planets with atmospheres dominated by H₂ and CO₂ for the first time. Second, we investigated microbial survival in these environments, conducting laboratory experiments on the growth and survival of <i>E. coli</i> K-12, focusing on the impact of different gas compositions. …”
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USE OF MOLECULAR MARKERS IN WHEAT BREEDING FOR RESISTANCE TO LEAF RUST AT THE LUKYANENKO RESEARCH INSTITUTE OF AGRICULTURE by E. R. Davoyan, L. A. Bespalova, R. O. Davoyan, Yu. S. Zubanova, D. S. Mikov, V. A. Filobok, J. N. Khudokormova

“…The resistance gene Lr37 was found in variety Morozko. Within a short time, F2 and F3 plants with introgression of genes Lr9, Lr19, Lr24, Lr37 were obtained. …”
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