Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions by Martin Škandík, Lara Friess, Guillermo Vázquez-Cabrera, Lily Keane, Kathleen Grabert, Mireia Cruz De los Santos, Mercedes Posada-Pérez, Austeja Baleviciute, Mathilde Cheray, Bertrand Joseph

“…Abstract The aging process is marked by a time-dependent deterioration in cellular functions, particularly the immune and neural systems. …”
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Enhancing Diagnostic Accuracy of Lung Nodules in Chest Computed Tomography Using Artificial Intelligence: Retrospective Analysis by Weiqi Liu, You Wu, Zhuozhao Zheng, Mark Bittle, Wei Yu, Hadi Kharrazi

“…ConclusionsThe AI system enhanced lung nodule detection, offering the possibility of earlier disease identification and timely intervention. Nevertheless, the initial reduction in accuracy underscores the need for standardized diagnostic criteria and comprehensive training for radiologists to maximize the effectiveness of AI-enabled diagnostic systems.…”
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一种降低南极磷虾油酸值的工艺研究 Technology of reducing acid value of Antarctic krill oil by 胥亚夫，俞存兵，余奕珂，郭忠，吴微，吕晶，郝兰 " XU Yafu, YU Cunbing, YU Yike, GUO Zhong, WU Wei, LYU Jing，HAO Lan"

“…The results showed that the optimal deacidification process conditions were as follows: mass-volume ratio of Antarctic krill oil to ethanol 1∶ 1, magnesium silicate addition amount 15% (based on the mass of Antarctic krill oil), and reaction time 1 h. Under the optimal conditions, the yield of deacidfied Antarctic krill oil reached 92.5%, the acid value was reduced from 11.53 mgKOH/g to 5.74 mgKOH/g, the phospholipid content decreased from 53.36% to 52.33%, and both fluidity and transparency were improved. …”
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Molecular prevalence and associated risk factors of Entamoeba spp. in donkeys in Shanxi Province, North China by Ze-Dong Zhang, Han-Dan Xiao, Dong-Yang Wang, Nan Su, Xun-Zhi Liu, Zi-Rui Wang, Shi-Chen Xie, Xing-Quan Zhu, Shuo Zhang, Wen-Wei Gao

“…Conclusions This study reports the occurrence and prevalence of Entamoeba spp. in donkeys worldwide for the first time to our knowledge. This not only expands the geographical distribution but also broadens the host range of Entamoeba spp., addressing the knowledge gap regarding the prevalence of Entamoeba spp. in donkeys, providing baseline data for carrying out prevention and control of Entamoeba spp. in donkeys in China. …”
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Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1... by Wangcheng Hu, Hui Luo, Yuekun Yang, Qiong Wang, Ni Hong, Guoping Wang, Aiming Wang, Liping Wang

“…A high-quality full-length genome sequence of the B. dothidea LW-Hubei isolate was obtained using Single Molecule Real-Time sequencing. It has high repeat sequence with 9.3% and DNA methylation existence in the genome. …”
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The Possibility or Impossibility of Stock Price Prediction: Evidence from the Petrochemical Industry by Masoud Alizadeh Chamazkoti, Mehdi Fathabadi, Mahmod Mahmodzadeh, Saleh Ghavidel Doostkouei

“…In addition, the shocks observed in Parsan, Shepdis, and Shatran companies are transient, with their effects dissipating over time, and the prices readjusted to the long-term mean, indicating the absence of weak efficiency. …”
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Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

“…Expression of mitophagy-related proteins (Cleaved PINK1, Parkin, SQSTM1/p62, Beclin-1, LC3B II/LC3B I), apoptosis-related proteins (Bcl-2, Cytochrome C, caspase-3, cleaved caspase3) and VDAC3 were assessed using western blot analysis and quantitative real-time PCR. The interaction between Parkin and VDAC3 was confirmed by immunofluorescence colocalization. …”
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Hubungan Aktivitas Fisik terhadap Kadar Hemoglobin pada Mahasiswa Anggota UKM Pandekar Universitas Andalas by Laura Kosasi, Fadil Oenzil, Amel Yanis

“…The study did by measuring the hemoglobin levels and filling the questionnaires of physical activity levels based on three scores, that works index score, sports index score, and free time index score. The results showed (1) mean hemoglobin levels at men is 15,98 g/dL with maximum 17,5 g/dL and minimum 13,1 g/dL, mean hemoglobin levels at women is 13,38 g/dL with maximum 15,8 g/dL and minimum 12,1 g/dL, (2) physical activity levels of Pandekar’s members from 28 respondents there are 25 active respondents and 3 underactive respondents. …”
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Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch by Shiyong Ling, Xi Luo, Bo Lv, Hua Wang, Mengzhi Xie, Kai Huang, Jingchuan Sun

“…Alkaline phosphatase (ALP) staining and alizarin red staining were used to detect the osteogenic differentiation ability of the two groups of cells. Real-time quantitative reverse transcription PCR (qRT-PCR) was used to detect the expression of miR-144-3p and PTEN in the two groups of cells after osteogenic differentiation. …”
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Unmet Supportive Care Needs of Lung Cancer Survival Patients at Different Cancer Stages and Treatment Phases by Lee PY, Chen YA, Tsai TH, Chen CY, Shieh SH

“…Therefore, Healthcare professionals should provide appropriate and timely individualized care to address these needs.Keywords: unmet care needs, lung cancer, survivor, cancer stages and treatment…”
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Efficacy and predictors of response to somatostatin analogues in patients with ectopic ACTH syndrome by Olga O. Golounina, Zhanna E. Belaya, Alla A. Markovich, Liudmila Y. Rozhinskaya, Galina A. Mel`nichenko, Natalia G. Mokrysheva, Ivan I. Dedov

“…Patients were conditionally divided into “responders” and “non-responders” at time points of 6, 12 and 24 months. Radiological efficacy was performed according to the RECIST 1.1. …”
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Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study by Xiao S, Ou J, Qiu W, Ye C, Li N, Chen S, Lai Y, Deng Z, Wu F, Shen Y

“…Subgroup analyses by sex, age, smoking status, race, body mass index, level of education, poverty-to-income ratio, respiratory symptoms, and comorbidities were performed in participants with the different spirometry classifications.Results: Overall, 24,691 participants were included, with a median follow-up time of 25.7 years. Of these, 19,969 had normal spirometry and 1,452 had PRISm. …”
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Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis. by Tara Cain, Jacinta Brinsley, Hunter Bennett, Max Nelson, Carol Maher, Ben Singh

“…<h4>Conclusions</h4>This systematic review suggests that CWI delivers time-dependent effects on inflammation, stress, immunity, sleep quality, and quality of life, offering potential practical applications for health practitioners considering CWI for stress management and wellbeing support. …”
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Perbedaan Efek Antibakteri Kapsul Minyak Bawang Putih (Garlic Oil) dan Kapsul Bubuk Bawang Putih (Garlic Powder) Terhadap Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia... by Ismail Fajri, Erly ., Elly Usman

“…The results of this study, garlic oil capsules and garlic powder capsules do not have the ability to produce a zone of inhibition against Staphylococcus aureus and Escherichia coli. Although 3 (three) time  repetitions, there were no antibacterial effect from garlic oil capsules and garlic powder capsules. …”
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Feasibility, acceptability and preliminary effects of a social network-based, peer-led HIV self-testing intervention among men in two Ugandan fishing communities, 2022 by Joseph KB Matovu, Aisha Twahiri Namwama, Linda Kemigisha, Geoffrey Taasi, Jennipher Nakabugo, Julius Wandabwa, Laura M. Bogart, Nuraan Fakier, Rhoda K. Wanyenze, Peter Olupot-Olupot, Joshua Musinguzi, David Serwadda

“…Nearly one-third of the HIV self-tested men (31.4%, n = 16) were first-time HIV-positive testers. Of these, 87.5% (n = 14) went for confirmatory HIV testing, 50.0% (n = 7) were confirmed as HIV-positive and 71.4% (n = 5) were linked to HIV care. …”
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Predictive modelling and identification of critical variables of mortality risk in COVID-19 patients by Olawande Daramola, Tatenda Duncan Kavu, Maritha J. Kotze, Jeanine L. Marnewick, Oluwafemi A. Sarumi, Boniface Kabaso, Thomas Moser, Karl Stroetmann, Isaac Fwemba, Fisayo Daramola, Martha Nyirenda, Susan J. van Rensburg, Peter S. Nyasulu

“…By using the Shapley Additive exPlanations (SHAP) model to interpret the mortality risk predictions, we identified the Length of stay (LOS) in the hospital, LOS in the ICU, Time to ICU from admission, days discharged alive or death, D-dimer (blood clotting factor), and blood pH as the six most critical variables for mortality risk prediction. …”
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Molecular Detection of Carbapenemase-Encoding Genes in Multidrug-Resistant Acinetobacter baumannii Clinical Isolates in South Africa by Yaw Adjei Anane, Teke Apalata, Sandeep Vasaikar, Grace Emily Okuthe, Sandile Songca

“…Colistin MIC was confirmed by the broth microdilution method. Real-time PCR was performed to investigate the presence of carbapenemase-encoding genes. …”
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In Vitro Antibacterial and Antioxidant Activities and Molecular Docking Analysis of Phytochemicals from Cadia purpurea Roots by Tsegu Kiros, Rajalakshmanan Eswaramoorthy, Yadessa Melaku, Aman Dekebo

“…Phytochemicals and antibacterial and antioxidant activities of Cadia purpurea roots were investigated herein for the first time. The phytochemical study led to the isolation of two compounds, di-(2-methylheptyl) phthalate (1) and 13-O-pyrrolecarboxyl lupanine (2), from methanol roots extract of C. purpurea. …”
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Enhancement of convolutional neural network for urban environment parking space classification by S. Rahman, M. Ramli, F. Arnia, R. Muharar, M. Ikhwan, S. Munzir

“…The solution offered at this time is the development of a smart parking system to overcome these problems. …”
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Fixed-Point Grover Adaptive Search for Quadratic Binary Optimization Problems by Akos Nagy, Jaime Park, Cindy Zhang, Atithi Acharya, Alex Khan

“…Finally, we give a heuristic argument that, with high probability and in <inline-formula><tex-math notation="LaTeX">$O (\frac{\log _{2} (n)}{\sqrt{\epsilon }})$</tex-math></inline-formula> time, this adaptive method finds a configuration that is among the best <inline-formula><tex-math notation="LaTeX">$\epsilon 2^{n}$</tex-math></inline-formula> ones.…”
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