Epidemiology of community-acquired pneumonia among hospitalised children in Indonesia: a multicentre, prospective study by Rina Triasih, Yan Mardian, Dewi Lokida, Helmia Farida, Herman Kosasih, Adhella Menur Naysilla, Arif Budiman, Chakrawati Hayuningsih, Moh Syarofil Anam, Dwi Wastoro, Mujahidah Mujahidah, Setya Dipayana, Amalia Setyati, Abu Tholib Aman, Nurhayati Lukman, Muhammad Karyana, Ahnika Kline, Aaron Neal, Chuen-Yen Lau, Clifford Lane

“…Children were excluded if they had been hospitalised for >24 hours; had malignancy or history of malignancy; a history of long-term (>2 months) steroid therapy, or conditions that might interfere with compliance with study procedures.Main outcome(s) measure(s) Causative bacterial, viral or mixed pathogen(s) for pneumonia were determined using microbiological, molecular and serological tests from routinely collected specimens (blood, sputum and nasopharyngeal swabs). …”
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Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta... by Romy Walker, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan G. Preston, Sharelle Joseland, Bernard J. Pope, Ana B.D. Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, Krzysztof Bernatowicz, Nicola Poplawski, Lesley Andrews, Emma Healey, Steven Gallinger, Robert C. Grant, Aung K. Win, John L. Hopper, Mark A. Jenkins, Giovana T. Torrezan, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan, Peter Georgeson

“…Conclusions: SBS18+SBS36 and SBS30 were enriched in adenomas at comparable proportions to those observed in CRCs from biallelic MUTYH and biallelic NTHL1 cases, respectively. Therefore, testing adenomas may improve the identification of biallelic cases and facilitate variant classification, ultimately enabling opportunities for CRC prevention.…”
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Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment by Meng Gao, Yu Wang, Liman Wei, Siyuan Li, Qiuyue Zhang, Zhongkang Yang, Mohan Bai, Yiming Yao, Lei Wang, Hongwen Sun

“…Notably, ΣRQ values for NOPEs were significantly higher than those of TOPEs (Mann-Whitney U test, p < 0.001), indicating their severe ecological risks in offshore sediment. …”
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Risco de transtorno alimentar e preocupações com a imagem corporal em mulheres com deficiência visual by Mariana Ribeiro Costa Portugal, Sarah Emanuelle Almeida Fontes da Silva, Julia Duppre de Abreu

“…Foram aplicados o Body Shape Questionnaire (BSQ), Body Checking Questionnaire (BCQ) e Eating Attitudes Test 26 (EAT-26), além da determinação do estado nutricional e coleta de informações sobre exercícios físicos, autonomia na aquisição de insumos e preparo de refeições e uso de mídias sociais. …”
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NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis by Jung Hwan Yoon, Jeong-Kyu Kim, Jung Woo Eun, Hassan Ashktorab, Duane T. Smoot, Suk Woo Nam, Won Sang Park

“…Statistical analyses, including Student’s t-test and ANOVA, were performed to determine the significance of our findings. …”
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Adaptive spatial-channel feature fusion and self-calibrated convolution for early maize seedlings counting in UAV images by Zhenyuan Sun, Zhenyuan Sun, Zhenyuan Sun, Zhi Yang, Zhi Yang, Yimin Ding, Yimin Ding, Boyan Sun, Boyan Sun, Saiju Li, Saiju Li, Zhen Guo, Zhen Guo, Lei Zhu, Lei Zhu

“…The efficacy of our approach was validated using the Early Maize Seedlings Dataset (EMSD), comprising 1,233 annotated images of early maize seedlings, totaling 83,404 individual annotations. Testing on this dataset demonstrated that RC-Dino outperformed existing models, including DINO, Faster R-CNN, RetinaNet, YOLOX, and Deformable DETR. …”
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Development of a horizontal transmission model to assess the effects of exposure to pathogenic E. cecorum during the hatching phase in broiler chickens by James Higuita, Marcela Arango, Aaron Forga, Mitch Rowland, Jundi Liu, Ross Wolfenden, Danielle Graham

“…The ANOVA was used to determine significant differences (P<0.05) for average body weight (BW) and average body weight gain (BWG) and EC quantification (Log10 CFU) with means being further separated using Student's t test. Chi-square was used to evaluate significant differences for hatchability, mortality, macroscopic lesions, and EC incidence. …”
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Efficacy of Chinese Medicine on Postoperative Rehabilitation of Non-small Cell Lung Cancer (NSCLC), a Randomized Controlled Study by Yifeng Gu MD, Yichao Wang MD, Huiling Zhou MD, Ao Qi PhD, Guanjin Wu MM, Jiaqi Li MMed, Congmeng Zhang MMed, Yong Yang MD, Jialin Yao MD, Wenxiao Yang PhD, Lingzi Su MMed, Yi Liu MMed, Xueqi Tian MMed, Jiajun Song MMed, Yabin Gong MD, Xiong Qin MD, Lijing Jiao PhD, Ling Xu PhD

“…Secondary outcomes included MOS item short form 36-Item Short Form Health Survey (SF-36) score, rate of complications, six-minute walk test (6MWT) distance, Leicester Cough Questionnaire (LCQ) score, numerical rating scale (NRS) score, and functional activity score (FAS). …”
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Early COVID-19 and protection from Omicron in a highly vaccinated population in Ontario, Canada: a matched prospective cohort study by Altynay Shigayeva, Christopher Kandel, Lubna Farooqi, Zoe Zhong, Anne-Claude Gingras, Brenda L. Coleman, Lois Gilbert, Wayne L. Gold, Maria Major, Tony Mazzulli, Samira Mubareka, Jelena Vojicic, Jingyan Yang, Pingping Zhang, Catherine Martin, Moe H. Kyaw, John M. McLaughlin, Allison McGeer

“…Methods We enrolled a cohort of adults in Ontario, Canada, with COVID-19 prior to October 2020 (early infection, EI), and a matched cohort with COVID-19 testing and a negative PCR (non-EI). Participants completed baseline surveys then surveys every two weeks until January 2023. …”
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Therapy for Dupuytren’s Disease (II): Collagenase Therapy vs. Limited Fasciectomy—A Long-Term Comparative Study by Nikolaus Wachtel, Francesca Romana Dingler, Constanze Kuhlmann, Sinan Mert, Elisabeth Maria Haas-Lützenberger, Verena Alt, Nicholas Moellhoff, Riccardo Giunta, Wolfram Demmer

“…Neither grip strength nor the pinch test showed significant differences when compared within each group or when comparing both groups. …”
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Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching ho... by Pengyu Zhang, Jingchen Hao, Yafen Zhang, Junfeng Su, Guozhuang Sun, Jun Xie, Jian Hu, Guocai Li

“…We identified bacterial isolates, collected clinical data, and performed antimicrobial susceptibility testing. Genome characteristics of isolates were investigated by whole genome sequencing. …”
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Protocol for a prospective quasi-experimental study on SARS-CoV-2 transmission during outdoor sports events in France: the COVID-ESO project by Frédéric Laurent, Philippe Vanhems, Christelle Elias, Pascal Roy, Sandrine Nail-Billaud, Patrick Basset, Emmanuelle Dantony, Mathieu Fauvernier

“…All individuals will be asked to perform saliva tests on the day of the event and 7 days after the event. …”
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Construction of a prognostic prediction model for colorectal cancer based on 5-year clinical follow-up data by Boao Xiao, Min Yang, Yao Meng, Weimin Wang, Yuan Chen, Chenglong Yu, Longlong Bai, Lishun Xiao, Yansu Chen

“…A modeling dataset containing 73 characteristic variables was established by collecting demographic information, clinical blood test indicators, histopathological results, and additional treatment-related information. …”
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Optic Nerve Head Hemoglobin Levels in Glaucoma: A Structural and Functional Correlation Study by Janaina A. G. Rocha, Diego T. Dias, Maria Betânia C. Lemos, Fábio N. Kanadani, Augusto Paranhos, Carolina P. B. Gracitelli, Tiago S. Prata

“…All participants underwent visual field (VF) testing (standard automated perimetry, SAP), color fundus imaging (mydriatic retinography), and peripapillary retinal nerve fiber layer (pRNFL) assessment through spectral-domain optical coherence tomography (SD-OCT). …”
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Joint fluid multi-omics improves diagnostic confidence during evaluation of children with presumed septic arthritis by Yolanda Peña-López, Naureen G. Tareen, Bo Zhang, Indu Raman, Carlos A. Arana, Chengsong Zhu, Yang Liu, Pratibha Selvakumar, Nicolai S. C. van Oers, Simrat Morris, Lora V. Hooper, Lawson A. B. Copley, Prithvi Raj

“…Methods Twelve children with suspected septic arthritis were prospectively enrolled to compare standard of care tests with a rapid multi-omics approach. The multi-omics combined bacterial 16S rRNA metagenomics, single cell transcriptomics, and proteomics on knee joint fluid specimens. …”
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Goose astrovirus induces apoptosis and endoplasmic reticulum stress in gosling hepatocytes by Zhihua Lu, Haiqin Li, Xiaona Gao, Duanfeng Fu, Haoyu Huang, Cheng Huang, Meiqin Wu, Xiaoquan Guo

“…Electron microscopy revealed expansion of the endoplasmic reticulum (ER) and aggregation of chromatin at the periphery. TUNEL testing further demonstrated an increase in the quantity of positive cells. …”
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The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (... by Noelle Robertson, Melanie J Davies, Thomas Yates, Gerry P McCann, Gaurav Singh Gulsin, Emer M Brady, Joanne V Wormleighton, Eylem Levelt, Oliver Rider, Jiliu Pan, Christopher Miller, Iain Squire, Mehak Asad, Fardad Soltani, Michelle Hadjiconstantinou, Rachel L Brown, Joanna M Bilak

“…Participants will undergo glycometabolic profiling, echocardiography, MRI for cardiovascular structure and function, body composition analysis (including visceral and subcutaneous adiposity quantification), Kansas City Cardiomyopathy Questionnaire (KCCQ) and Six-Minute Walk Test (6MWT), at baseline and 12 weeks. An optional 24-week assessment will include non-contrast CMR, 6MWT, KCCQ score. …”
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Factors associated with the formation of neutralizing antibodies post-vaccination: a lesson from COVID-19 vaccination by Hana Ratnawati, Fen Tih, Grace Puspasari, Allen A. Pelapelapon, Steven Felim

“…Descriptive data analysis was performed as mean ± standard deviation to show the characteristics of the sample. Students’ t-tests and multivariate and univariate regression analyses were used to evaluate the data. …”
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Time without PSA recurrence after radical prostatectomy as a predictor of future biochemical recurrence, metastatic disease and prostate cancer death: a prospective Scandinavian co... by Mats Steinholtz Ahlberg, Hans-Olov Adami, Hans Garmo, Lars Holmberg, Anna Bill-Axelson, Ove Andren, Gunnar Steineck, Jan-Erik Johansson

“…Objective Although surveillance after radical prostatectomy routinely includes repeated prostate specific antigen (PSA)-testing for many years, biochemical recurrence often occurs without further clinical progression. …”
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A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome by Ying Zhang, Yu Chen, Fa-Ying Liu, Jing-Wen Fu, Xian-Xian Liu, Jun Tan, Ou-Ping Huang, Yang Zou

“…And it was ranging from 7.89e-5 to 1.47e-4 in public databases. Fisher’s exact test indicated that the allele frequencies in PCOS were p < 0.05 compared to both the controls and the databases. …”
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