Effect of EOG Signal Filtering on the Removal of Ocular Artifacts and EEG-Based Brain-Computer Interface: A Comprehensive Study by Malik M. Naeem Mannan, M. Ahmad Kamran, Shinil Kang, Myung Yung Jeong

“…Results from statistical testing of time and frequency domain metrics suggested that a low-pass frequency between 6 and 8 Hz could be used as the most optimal filtering frequency of EOG signals, both to maximally overcome/minimize the effect of bidirectional contamination and to achieve good results from artifact removal algorithms. …”
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Preparing healthcare leaders of the digital age with an integrative artificial intelligence curriculum: a pilot study by Soo Hwan Park, Roshini Pinto-Powell, Thomas Thesen, Alexander Lindqwister, Joshua Levy, Rachael Chacko, Devina Gonzalez, Connor Bridges, Adam Schwendt, Travis Byrum, Justin Fong, Shahin Shahsavari, Saeed Hassanpour

“…Students’ confidence in explaining the content objectives (high-level knowledge, implications, and limitations of AI) was measured before and after each block and compared using Mann-Whitney U tests. Students reported significant increases in confidence in describing the content objectives after all four blocks (Immunology: U = 4.5, p = 0.030; Hematology: U = 1.0, p = 0.009; Cardiology: U = 4.0, p = 0.019; Pulmonology: U = 4.0, p = 0.030) as well as an average overall satisfaction level of 4.29/5 in rating the curriculum content. …”
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CD2AP deficiency aggravates Alzheimer’s disease phenotypes and pathology through p38 MAPK activation by Yan-Yan Xue, Zhe-Sheng Zhang, Rong-Rong Lin, Hui-Fen Huang, Ke-Qing Zhu, Dian-Fu Chen, Zhi-Ying Wu, Qing-Qing Tao

“…Then, we generated and characterized an APP/PS1 mouse model with neuron-specific Cd2ap deletion, using immunoblotting, immunofluorescence, enzyme-linked immunosorbent assay, electrophysiology and behavioral tests. Additionally, we established a stable CD2AP-knockdown SH-SY5Y cell line to further elucidate the specific molecular mechanisms by which CD2AP contributes to AD pathogenesis. …”
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Genomic Insights into Blood Pressure Regulation: Exploring Ion Channel and Transporter Gene Variations in Jordanian Hypertensive Individuals by Mansour Abdullah Alghamdi, Laith AL-Eitan, Rasheed Ibdah, Islam Bani Khalid, Salma Darabseh, Maryam Alasmar, Asaad Ataa

“…The haplotype frequencies were investigated using the SNPStats web tool, and the genotype and allele frequencies of the studied variants were assessed using the χ² test. <i>Results</i>: Sixteen single nucleotide polymorphisms (SNPs) from nine genes were evaluated. …”
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One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction by Porfirio Estrada-Rojas, Juan Francisco Hernández-Paz, Claudia Alejandra Rodríguez-González, Mónica Elvira Mendoza-Duarte, Santos Adriana Martel-Estrada, Laura Elizabeth Valencia-Gómez, Héctor Camacho-Montes, Imelda Olivas-Armendáriz

“…Fourier-transform infrared (FTIR) spectroscopy confirmed the structural integrity of BSA after functionalization, while x-ray diffraction (XRD) analysis verified the formation of CuS and Cu _2 S crystals. Additional tests, including fluorescence and UV–vis spectroscopy, validated the optical properties of the quantum dots. …”
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Comparative analysis of viability, proliferation, and mineralization potential of human pulp and osteoblastic cells exposed to different bioceramic endodontic sealers by Marcos Coelho Santiago, Gustavo Henrique de Oliveira Salles, Gustavo Gomes de Lima, Laudimar Alves de Oliveira, Loise Pedrosa Salles

“…Statistical analysis was performed using Two-way ANOVA for calcium release and wound healing assays and One-way ANOVA for other assays, with post-test Bonferroni correction. The results were significant when p < 0.05. …”
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Designing and Optimizing Heat Storage of a Solar-Assisted Ground Source Heat Pump System in China by Yan Gao, Zhi Sun, Xinxing Lin, Chuang Wang, Zongyu Sun, Yanhong Chen

“…Long-term operation will test the matching rate of the compensation system with the conventional GSHP system. …”
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Precise Detection of Gene Mutations in Fine-Needle Aspiration Specimens of the Papillary Thyroid Microcarcinoma Using Next-Generation Sequencing by Feng-xia Yu, Min-xia Hu, Han-xue Zhao, Li-juan Niu, Xue-yu Rong, Wei-hua Li, Qiang Zhu, Jian-ming Ying, Ning Lyu

“…A total of 135 FNA samples out of 135 patients with suspected PTMC were submitted for mutation testing using NGS. NGS was successfully performed in 114 specimens, while the remaining 21 samples were excluded due to insufficient amount/poor quality of DNA and sequencing failure. …”
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Advancing Objective Mobile Device Use Measurement in Children Ages 6–11 Through Built-In Device Sensors: A Proof-of-Concept Study by Olivia L. Finnegan, R. Glenn Weaver, Hongpeng Yang, James W. White, Srihari Nelakuditi, Zifei Zhong, Rahul Ghosal, Yan Tong, Aliye B. Cepni, Elizabeth L. Adams, Sarah Burkart, Michael W. Beets, Bridget Armstrong

“…Five machine learning models, logistic regression (LR), support vector machine, neural net (NN), k-nearest neighbors (k-NN), and random forest (RF), were trained using 57 features generated from the sensor output to perform multiclass classification. A train-test split of 80%–20% was used for model fitting. …”
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Effect of older age and/or ACL injury on the dose–response relationship between ambulatory load magnitude and immediate load-induced change in serum cartilage oligomeric matrix pro... by Simon Herger, Corina Nüesch, Anna-Maria Liphardt, Christian Egloff, Annegret Mündermann

“…Blood samples were collected immediately before and after a walking stress at 80%, 100%, or 120% bodyweight (BW) on 3 test days and analyzed for sCOMP concentration. Linear models were used to estimate the effect of age, knee status (unilateral ACL injury, 2–10 years prior), and sex on sCOMP(tpre), ∆_sCOMP(tpost), and the dose–response between ambulatory load magnitude and ∆_sCOMP(tpost). …”
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Risk assessment and hierarchical classification of foodborne disease epidemics during major events in Beijing: an empirical study based on surveillance data analysis by Jinru JIANG, Yangbo WU, Tongyu WANG, Chao WANG, Yanlin NIU, Di WANG, Liping LI, Qian CHEN, Yao ZHAO, Xiaochen MA

“…Prevention measures should focus on high and medium risk factors and those at the top of the Borda ordinal, and carry out monitoring and testing in the procurement, storage, processing and other links of raw materials, formulate recipes scientifically, do a good job in personnel health and training, and prevent cross-contamination.…”
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Food insecurity and the risk of HIV acquisition: findings from population-based surveys in six sub-Saharan African countries (2016–2017) by Danielle Barradas, Nicholus Mutenda, Hetal Patel, Avi J Hakim, Lloyd Mulenga, Sally Findley, Andrea Low, George Rutherford, Sarah Ayton, Elizabeth Gummerson, Amee Schwitters, Rogerio Bonifacio, Mekleet Teferi, James Juma, Claudia Ahpoe, Choice Ginindza, Samuel Biraro, Karam Sachathep, Ahmed Saadani Hassani, Willford Kirungi, Keisha Jackson, Leah Goeke, Neena Philips, Jennifer Ward, Steven Hong

“…Objective To assess the potential bidirectional relationship between food insecurity and HIV infection in sub-Saharan Africa.Design Nationally representative HIV impact assessment household-based surveys.Setting Zambia, Eswatini, Lesotho, Uganda and Tanzania and Namibia.Participants 112 955 survey participants aged 15–59 years with HIV and recency test results.Measures Recent HIV infection (within 6 months) classified using the HIV-1 limited antigen avidity assay, in participants with an unsuppressed viral load (&gt;1000 copies/mL) and no detectable antiretrovirals; severe food insecurity (SFI) defined as having no food in the house ≥three times in the past month.Results Overall, 10.3% of participants lived in households reporting SFI. …”
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Dependencia a los videojuegos y la familia de adolescentes encrucijadenses by Juan Ricardo Sotés Martínez, Yeany Mesa Rodríguez, Aracelys Pérez Borroto González, Yumary Moya Feitó, Yenisley Jiménez Cabrera, Saily Navarro Moya

“…Se aplicó una entrevista, el Test de dependencia a los videojuegos (TDV), la Prueba para medir funcionamiento familiar (FF-SIL) y el Inventario de problemas de salud familiar (IPSF). …”
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The Protective Effects of Annexin A1 in Acute Lung Injury Mediated by Nrf2 by Hui Huang, Yuqin Shi, Yuequan Zhou

“…Lung injury was assessed through histopathology, pulmonary wet‐to‐dry (W/D) ratio, cell counting of bronchoalveolar lavage fluid (BALF), oxidative stress analysis, and noninvasive pulmonary function testing. Gene and protein expression levels were measured using RT‐PCR, ELISA, and western blot analysis. …”
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Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder by Yilu Zhao, Zhao Fu, Eric J. Barnett, Ning Wang, Kangfuxi Zhang, Xuping Gao, Xiangyu Zheng, Junbin Tian, Hui Zhang, XueTong Ding, Shaoxian Li, Shuyu Li, Qingjiu Cao, Suhua Chang, Yufeng Wang, Stephen V. Faraone, Li Yang

“…The convolutional neural network (CNN) model, using variants with genome-wide P values less than E-02 (5516 SNPs), demonstrated the best performance with mean squared error (MSE) equals 0.012 (Accuracy = 0.83; Sensitivity = 0.90; Specificity = 0.75) in the validation dataset, 0.081 in an independent test dataset (Acc = 0.61, Sensitivity = 0.81; Specificity = 0.26). …”
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Cinnamic Acid Compounds (<i>p</i>-Coumaric, Ferulic, and <i>p</i>-Methoxycinnamic Acid) as Effective Antibacterial Agents Against Colistin-Resistant <i>Acinetobacter baumannii</i> by Alaaddin Korkut, Serap Özkaya Gül, Esra Aydemir, Hakan Er, Elif Odabaş Köse

“…The combination effects of the compounds with colistin (COL) were evaluated using a checkerboard synergy test. The combinations exhibited a synergistic effect and caused a 128- to 16-fold decrease in COL MIC values. …”
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Bit selection method based on the rock drillability characteristics and principal component analysis of rock-breaking indicators by Yang Hu, Xian Xinlong, Zhou Penggao, Li Zhen, Wei Ruihua, Liang Junqiao, Xiong Shilong

“…Therefore, the indoor test of core mechanical parameters was carried out, and the logging inversion model of seven rock mechanics and anti-drilling characteristic parameters in the deep strata of the southern margin of Junggar Basin was established by nonlinear multiple regression method. …”
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Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress by Saakshi Saini, Viney Kumar, Swati Haldar, Samrat Chauhan, Pratibha Demiwal, Souvik Ghosh, Sumeet Gupta, Debabrata Sircar, Bidhan Mahajon, Partha Roy

“…The anxiolytic activity of SM was demonstrated by improved behavior of the animals in the elevated plus maze test and increased SOD activity in the brain. SM exhibited the most effective improvements in anxiety disorder at a dose of 100 mg/kg body weight in rats. …”
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Effect of arm-ergometry versus treadmill supervised exercise on health-related quality of life and mental health in patients with peripheral artery disease: secondary outcomes from... by Sandra Magalhães, Mário Santos, Sofia Viamonte, Fernando Ribeiro, Joana Martins, Cristine Schmidt, Henrique Cyrne-Carvalho

“…Differences between groups in the change from baseline to the end of the study were analyzed using ANCOVA, adjusted for baseline values, or the Mann-Whitney U test. Results Fifty-six patients (66 ± 8.4 years; 87.5% male) were included: AEx (n = 28) and TEx (n = 28). …”
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The Use of Patient-Reported Outcomes in Clinical Practice: A National Survey of Hand Surgeons by Stephanie Choo, MD, Rown Parola, MD, Benjamin Kirby, MD, Daniel A. London, MD

“…Associations between variables were determined by Fischer exact tests and logistic regression. Results: A total of 419 surveys were completed from the 4,523 individuals contacted, representing a 9.3% response rate. …”
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