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1801
Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats
Published 2019-01-01“…There were no test item-related changes observed in haematology, coagulation, urinalysis, thyroid hormonal analysis, terminal fasting body weights, organ weights, gross pathology and histopathology. …”
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1802
Intermediate MCAD Deficiency Associated with a Novel Mutation of the ACADM Gene: c.1052C>T
Published 2015-01-01“…The replacement is a nonconservative amino acid change that occurs in the C-terminal all-alpha domain of the MCAD protein. Here we report the finding of a novel missense mutation, c.1052C>T (p.Thr326Ile), in the ACADM gene. …”
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1803
The Compound Expression of HSP90 and INOS in the Testis of Diabetic Rats as Cellular and Pathologic Adverse Effects of Diabetes
Published 2020-01-01“…After the experiment had finished, all rats were terminated and prepared for routine histological and immunohistochemical examination. …”
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1804
Midcourse Guidance Law Based on High Target Acquisition Probability Considering Angular Constraint and Line-of-Sight Angle Rate Control
Published 2016-01-01“…Numerical simulations demonstrates that, compared with the proportional navigation guidance (PNG) law and the near-optimal spatial midcourse guidance (NSMG) law, BPN guidance law demonstrates satisfactory performances and can meet both the midcourse terminal angular constraint and the LOS angle rate requirement.…”
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1805
Element Geochemical Analysis of the Contribution of Aeolian Sand to Suspended Sediment in Desert Stream Flash Floods
Published 2014-01-01“…In arid zones, many aeolian dune-fields terminate in stream channels and deliver aeolian sand to the channels. …”
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1806
A novel pulse multiplication circuit for reducing harmonic distortion of 12 pulse rectifiers in aircraft electrical power systems
Published 2023-06-01“…The novel PMC consists of two TIPRs (TIPR1 and TIPR2), an auxiliary single‐phase diode bridge (including four diodes D1 to D4), and two auxiliary diodes D21 and D22, which are connected directly to the output terminal of the DBRs (DBR1 and DBR2). The simulation and experimental results confirm the high capability of the proposed PMC to reduce the harmonic distortion of the input current, so that by using the proposed PMC, the input current is almost sinusoidal and the THD of the input current is less than 3%. …”
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1807
Blockade of NR2A-Containing NMDA Receptors Induces Tau Phosphorylation in Rat Hippocampal Slices
Published 2010-01-01“…This effect seemed to be Ser199 specific as there was no increase in phosphorylation at Ser262 and Ser409 residues located in the microtubule-binding and C-terminal domains of Tau proteins, respectively. From a mechanistic perspective, our study revealed that blockade of NR2A-containing receptors influences Tau phosphorylation probably by increasing calcium influx into neurons, which seems to rely on accumulation of new NR1/NR2B receptors in neuronal membranes and could involve the cyclin-dependent kinase 5 pathway.…”
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1808
Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63
Published 2013-01-01“…The p53/p63/p73 family is expressed as multiple protein isoforms due to a combination of alternative promoter usage and C-terminal alternative splicing. These isoforms can mimic or interfere with one another, and their balance ultimately determines biological outcome in a context-dependent manner. …”
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1809
Bone‐Targeted Fluoropeptide Nanoparticle Inhibits NF‐κB Signaling to Treat Osteosarcoma and Tumor‐Induced Bone Destruction
Published 2025-01-01“…The fluorous‐tagged NBD peptide is further co‐assembled with an oligo (aspartic acid) terminated fluoropeptide to form bone‐targeted peptide nanoparticles for osteosarcoma treatment. …”
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1810
Stochastic Modelling and Simulation of Free Radical Polymerization of Styrene in Microchannels using a Hybrid Gillespie Algorithm
Published 2023-02-01“…In addition, especially in pilot experimentations, a micro or milli-reactor has been known widely to be efficient in monitoring the microstructural end-use features or properties of the polymer as the chain propagates and ultimately terminates. However, the limitations posed by using micro or milli-reactors in process intensification such as clogging of pores can be a bottleneck when tracking the common phenomena associated with FRP such as cage, gel, and glass effects. …”
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1811
Insights into the Allosteric Regulation of Human Hsp90 Revealed by NMR Spectroscopy
Published 2024-12-01“…One of the possibilities is allosteric regulation by its natural allosteric modulators—nucleotides, co-chaperones and client proteins—and synthetic small-molecule allosteric modulators, such as those targeting the middle domain or the C-terminal domain (CTD) of Hsp90. Since no experimentally determined structure of a small-molecule allosteric modulator bound to the CTD of human Hsp90 has yet been obtained, the challenge for a structure-based design of allosteric modulators remains. …”
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1812
Guanine-based spin valve with spin rectification effect for an artificial memory element
Published 2025-01-01“…The non-volatile resistance states of the multiferroic spintronic junction with two-terminals are manipulated by a combined action of small external magnetic and electric fields. …”
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1813
Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits in Adult Male Rats
Published 2016-01-01“…Herein, we examined the effects of an acute psychological stress (120 min restraint) on gene expression patterns of enzymes along the kynurenine pathway over a protracted time-course (1–24 h post-stress termination) within the amygdala, hippocampus, hypothalamus, and medial prefrontal cortex. …”
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1814
Human parathyroid hormone fragment stimulates the de novo synthesis of prostaglandin endoperoxide synthase in chick calvaria
Published 1993-01-01“…The human parathyroid hormone N-terminal fragment [hPTH-(1–34)] increases the conversion of exogenous unsaturated fatty acids to prostaglandins (PGs) in calvarial homogenates. …”
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1815
Persistent Mosaicism for 12p Duplication/Triplication Chromosome Structural Abnormality in Peripheral Blood
Published 2013-01-01“…Utilization of fluorescence in situ hybridization (FISH) identified three copies of probes from the end of the short arm of chromosome 12 (TEL(12p13) locus and the subtelomere (12p terminal)) on the structurally abnormal chromosome 12. …”
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1816
Faecopneumothorax Caused by Perforated Diaphragmatic Hernia
Published 2020-01-01“…A left-sided hemicolectomy with terminal transversostomy and splenectomy were performed. …”
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1817
An Incremental Regularization Kernel Randomized Neural Network for Electrical Energy Output Prediction in Combined Cycle Power Plant
Published 2024-01-01“…Moreover, the number of nodes and the expected tolerance are used as criteria for terminating the kernel-based incremental learning process to achieve a compact network structure. …”
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1818
Studies on the Pinctada fucata BMP-2 Gene: Structural Similarity and Functional Conservation of Its Osteogenic Potential within the Animal Kingdom
Published 2013-01-01“…The sequence, SVPKPCCVPTELSSL, within the C-terminal portion of Pinctada fucata BMP-2, is homologous to the knuckle epitope of human BMP-2. …”
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1819
Design of Shadow Filter Using Low-Voltage Multiple-Input Operational Transconductance Amplifiers
Published 2025-01-01“…The MI-OTA is designed to provide multiple-input differential terminals using the multiple-input bulk-driven MOS transistor (MIBD-MOST) technique, allowing differential input signals to be converted into current output through its transconductance gain. …”
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1820
Neutral zone closing overvoltage characteristics analysis in traction power supply system for group trains
Published 2025-01-01“…The expression of the train terminal voltage at the moment of closing is solved by reasonable assumptions, which reveals the formation reasons of the closing overvoltage in terms of the qualitative relationship. …”
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