Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy by Mickensone Andre, Nagesh Kolishetti, Adriana Yndart, Arti Vashist, Madhavan Nair, Andrea D. Raymond

“…HC69 cells, a microglial model of HIV latency, contain an HIV promoter long terminal repeat (LTR)-GFP reporter and were used for testing the efficacy of a two-step magnetoelectric nanoparticle (MENP) and extracellular vesicle (xEV) latency-targeting (MELT) nanotherapeutic. …”
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Fossil Diatoms Reveal Natural and Anthropogenic History of Jackson Lake (Wyoming, USA) by John Dilworth, Jeffery R. Stone, Kevin M. Yeager, J. Ryan Thigpen, Michael M. McGlue

“…The core spans the termination of the Little Ice Age and extends to the present day (∼1654–2019 CE). …”
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Prednisolone pharmacokinetics in dogs with protein‐losing enteropathy by Sara A. Jablonski, Jessica L. Strohmeyer, John P. Buchweitz, Andreas F. Lehner, Daniel K. Langlois

“…Results The PLE dogs had a shorter half‐life of the terminal slope than control dogs (harmonic mean of 1.3 vs 1.8 hours; P = .05) whereas the percentage of serum prednisolone that was non‐protein bound was higher in PLE dogs than in control dogs (median of 15.7% vs 6.7%; P = .02) at T1. …”
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Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury by Georgios Michalettos, Fredrik Clausen, Elham Rostami, Niklas Marklund

“…Treatment with 7,8-DHF led to reduced axonal swellings at 2 and 7 dpi, as visualized by SMI-31 (Neurofilament Heavy Chain) immunofluorescence, and reduced number of TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labelling)/CC1-positive mature oligodendrocytes at 2 dpi in the perilesional white matter. …”
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EFFECTS OF BIRTH TYPE ON FATTENING PERFORMANCE AND CARCASS CHARACTERISTICS OF D’MAN LAMBS IN SOUTHWESTERN ALGERIAN OASES by Boubekeur Abderrahmen, Souddi Mohammed, Benidir Mohammed

“…This requires more care on the part of the breeder and the use of large quantities of concentrated feed both for the mothers and for raising and fattening lambs. Thus, terminal crossbreeding with other local breeds may improve the performance of multiple-born lambs.…”
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Timosin alpha-1 immunomodulating properties by M. V. Mayevskaya

“…It is shown, that Timosin alpha-1 efficacy is increased eventually and is more pronounced at the end of monitoring period after termination of therapy. According to original studies The Asian-Pacific association for the study of the liver (APASL) included Timosin alpha-1 in the list of immunomodulating agents for CHB treatment besides standard and pegilated interferon-a (PEG-IFN-a). …”
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The Fibularis Quartus Muscle: A Cadaveric Case Report with Historical, Embryological, Molecular and Clinical Considerations by Dibakar Borthakur, Rajesh Kumar, Namaschivayam G R, Mohammed Ahmed Ansari, Seema Singh

“…The FQ was proximally attached to the FB and adjacent distal third of the fibula, which then formed a flat fusiform muscle belly and eventually terminated through a rounded tendon via its attachment to the peroneal trochlea of the calcaneus. …”
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Extracellular domain of TREM2 possess two distinct ligand recognition sites: Insights from machine-learning guided docking and all-atoms molecular dynamics simulations by Sarbani Mishra, Preety Sthutika Swain, Sanghamitra Pati, Budheswar Dehury

“…Besides the known binding site formed by complementarity-determining regions (CDR) 1 and CDR2 loops, which enables the binding of different anionic ligands, our study identifies the presence of second binding site formed by β-strands towards the C-terminal end. We observe a dense network of hydrophobic contacts formed between the explored ligands and CDR loops and β-strands, specifically CDR1, CDR2, β-strand C', loop connecting β-strand D and E, and loop connecting β-strand E and F. …”
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Characteristics Associated with Acute-Phase Response following First Zoledronic Acid Infusion in Brazilian Population with Osteoporosis by Bruno S. A. Ferreira, Bernardo M. da Cunha, Luciana P. Valadares, Larissa A. Moreira, Frederico G. A. Batista, Cristiane da F. Hottz, Marina M. P. Lins, Gabriel G. R. Magalhães, Luanna M. de Arruda, Sergio H. R. Ramalho

“…Clinical demographics (age, sex, diabetes, smoking, body mass index, and previous oral bisphosphonate use) and laboratory data (calcium, parathyroid hormone, renal function, and serum 25-hydroxyvitamin D and carboxy-terminal crosslinked telopeptide of type 1 collagen [CTX], both before and after infusion) were compared between patients with and without APR. …”
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Mild drought conditions at the tillering stage promote dry matter accumulation and increase grain weight in drip-irrigated spring wheat (Triticum aestivum L.) by Yilin Ma, Jingyi Cai, Shuting Bie, Ziqiang Che, Guiying Jiang, Jianguo Liu

“…Correlation and principal component analyses showed that grain weight was highly significantly and positively correlated with stem sheath, leaf, and spike dry matter accumulation, amount of nutrient organ post-flowering transports, transport rate, contribution rate, the onset and the termination time of the rapid growth period, Vmax, and Vmean, and stem sheath and spike dry matter accumulation had a direct effect on grain weight. …”
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NEW ROLE FOR THE TEACHER: PREVENT STUDENTS FROM COMPLETELY ABANDONING THEMSELVES TO AI AND RELINQUISHING CONTROL OVER THEIR LEARNING. Illustration for foreign languages for specifi... by Felicia CONSTANTIN

“…Students jump on the immediate benefits of smart devices because they don't know what they can or what they have to do to avoid turning themselves into AI terminals. In the context of the redefinition or annihilation of roles in education, the teacher has a new responsibility, in addition to those he has traditionally: he has to become an influential person giving warnings and preventing students from abandoning themselves to AI, relinquishing control over their learning and development. …”
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Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells by Rou-Yi Fang, Yueh-Wen Liu, Yih-Gang Goan, Jen-Jie Lin, Jui-Hsin Su, Wen-Tung Wu, Yu-Jen Wu

“…In addition, the treatment with this compound led to the inhibition of phosphorylation in extracellular signal-regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK). It also curtailed the expression of several key proteins including focal adhesion kinase (FAK), protein kinase C (PKC), growth factor receptor-bound protein 2 (GRB2), Rac, Ras, Rho A, mitogen-activated protein kinase kinase kinase 3 (MEKK3), and mitogen-activated protein kinase kinase 7 (MKK7). …”
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Development and validation of a risk assessment model for predicting the failure of early medical abortions: A clinical prediction model study based on a systematic review and meta... by An-Hao Liu, Bin Xu, Xiu-Wen Li, Yue-Wen Yu, Hui-Xin Guan, Xiao-Lu Sun, Yan-Zhen Lin, Li-Li Zhang, Xian-Di Zhuo, Jia Li, Wen-Qun Chen, Wen-Feng Hu, Ming-Zhu Ye, Xiu-Min Huang, Xun Chen

“…The final risk factors consisted of gestational age, maternal age, parity, previous termination of pregnancy, marital status, type of residence, and differences between gestational age calculated using the last menstrual period and that measured via ultrasound. …”
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Zebularine Promotes Hepatic Differentiation of Rabbit Bone Marrow Mesenchymal Stem Cells by Interfering with p38 MAPK Signaling by Yong-Heng Luo, Juan Chen, En-Hua Xiao, Qiu-Yun Li, Yong-Mei Luo

“…Therefore, this study demonstrated that treatment with zebularine exhibited terminal hepatic differentiation of BMMSCs in vitro in association with hepatocyte growth factor; p38 pathway at least partially participates in zebularine-induced hepatic differentiation of rabbit BMMSCs.…”
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First African case report of hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome due to inverted duplication and deletion of chromosome 10p by Tumelo M. Satekge, Glenrose Rikhotso, Bianca Rossouw, Bronwyn Dillon, Fiona Baine-Savanhu

“…The dysmorphic features, global developmental delay and hypoparathyroidism associated with persistent and severe hypocalcaemia led to the investigation by CMA which detected a 9.5 Mb heterozygous terminal loss of chromosome 10p15.3p14; GATA3 is included in this region. …”
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Ensuring the freedom to conclude an employment contract and gender equality in employment under martial law by K. Yu. Melnyk

“…In order to strengthen the regulatory provision of gender equality in employment, it is proposed to: 1) delete the word “may” after the word “employers” and change the ending of the word “implement” in Part 4 of Article 17 of the Law of Ukraine “On Ensuring Equal Rights and Opportunities of Women and Men”; 2) to supplement the employer’s duties provided for in Part 2 of Article 17 of the Law of Ukraine “On ensuring equal rights and opportunities for women and men”, as follows: “do not allow discrimination based on gender when concluding, changing and terminating an employment contract”.…”
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Oral Glutamine Supplementation Benefits Jejunum but Not Ileum by Paul E Hardy, Karen L Madsen, Olin G Thurston, Stewart M Hamilton, Ningren Cui, Richard N Fedorak

“…The ability of enteral glutamine to support jejunal architecture and metabolism is well established, but its effect on intestinal absorptive function, especially in the terminal ileum, remains undetermined. The purpose of this study was to develop a functional ileal fluid absorption surgical injury model and to determine if oral glutamine supplementation would be beneficial in accelerating healing and restoring function. …”
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Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV‐J Strain Isolated From Chinese Hetian Chickens by Tianyu Lei, Liyun Zhuang, Tingting Dai, Qun Niu, Yinli Bao, Weiming Lin, Cuiqin Huang, Xintian Zheng

“…Genome‐wide genes, including gag, pol, gp85, and long terminal repeat (LTR), were compared. Recombination sites were analysed using RDP5 and SimPlot software. …”
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A strategy to improve the adsorption capacity of OPs-dye pollutants from the aqueous environment using adsorbents based on 2D transition metal carbides (V2CTx) by Ali Bina, Heidar Raissi

“…Techniques based on adsorption and extensive use of two-dimensional (2D) transition metal carbides (MXenes) with the presence of terminal functional groups have provided a high potential in the separation of organic aromatic pollutants. …”
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Frameshift variation in the HMG-CoA reductase gene and unresponsiveness to cholesterol-lowering drugs in type 2 diabetes mellitus patients by Esmat Khaleqsefat, Khder Hussein Rasul, Ramiar Kamal Kheder, Sonia Baban, Jamil Baban

“…As a result, translation was prematurely terminated, leading to the production of truncated proteins.…”
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