Real-Life Diagnostic Accuracy of MRI in Prenatal Diagnosis by Manuel Recio Rodríguez, Cristina Andreu-Vázquez, Israel J. Thuissard-Vasallo, Raquel Cano Alonso, Carmina Bermejo López, Ines Tamarit Degenhardt, Pilar Martínez Ten

“…Fetal MRI provided useful information for the perinatal management and prognosis over fetal ultrasound when findings of the fetal MRI changed the postnatal prognosis, leaded to the decision to legally terminate the pregnancy, changed prenatal or postnatal follow-up, or helped in the planning of prenatal or postnatal treatment. …”
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Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells by Hyun-Jae Jang, Kang-Hoon Kim, Eun-Jae Park, Jeong A. Kang, Bong-Sik Yun, Seung-Jae Lee, Chan Sun Park, Soyoung Lee, Seung Woong Lee, Mun-Chual Rho

“…Its inhibitory activity of proinflammatory mediators is contributed by suppressing the activation of nuclear transcription factor- (NF-) κB and mitogen-activated protein kinase (MAPK) signaling cascades including p65, inhibition of NF-κB (IκB), extracellular signal-regulated kinase (ERK), c-Jun NH2-terminal kinase (JNK), and p38. Therefore, these results demonstrated that diterpenoids 1 and 3 obtained from C. orbiculatus may be considered a potential candidate for the treatment of inflammatory diseases.…”
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Comparative assessment of <i>Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus</i> and <i>Saccharomyces boulardii</i> efficacy at d... by V. T. Ivashkin, O. M. Drapkina, A. A. Sheptulin, O. S. Shifrin, Ye. A. Poluektova, S. Yu. Kuchumova

“…Besides that presence of BOS was investigated by hydrogen breath test with lactulose, quality of a life was determined using The Short Form-36 (SF-36) questionnaire prior to treatment onset and its termination. Treatment lasted for 28 days.Results. In group of the patients who received Florasan-D and Enterol, in contrast to as placebo group improvement in relation to severity of main clinical symptoms was marked, quality of a life score increased. …”
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Extensional forearc structures at the transition from Alaska to Aleutian Subduction Zone: slip partitioning, terranes and large earthquakes by Kahrizi, Amin, Delescluse, Matthias, Chamot-Rooke, Nicolas, Pubellier, Manuel, Bécel, Anne, Shillington, Donna, Nedimović, Mladen, Bulois, Cédric

“…We investigate for the first time the origin of the trench-parallel extension and explain the horsetail geometry of the Central Sanak Basin as the termination of a slip-partitioning right-lateral strike slip fault. …”
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From canonical to unique: extension of a lipophilicity scale of amino acids to non-standard residues by Antonio Viayna, Paulina Matamoros, David Blázquez-Ruano, William J. Zamora

“…To this end, we employed two structural models, Model 1 and 2, differentiated solely by their C-terminal capping groups using an N- or O-methyl substituent, respectively. …”
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Health implications of racial differences in serum growth differentiation factor levels among men with obesity by Siresha Bathina, Virginia Fuenmayor Lopez, Mia Prado, Elliot Ballato, Georgia Colleluori, Maryam Tetlay, Dennis T Villareal, Sanjay Mediwala, Rui Chen, Clifford Qualls, Reina Armamento‐Villareal

“…Serum GDF15, osteocalcin, C‐terminal telopeptide, sclerostin, adiponectin, leptin, estradiol, testosterone, follicle‐stimulating hormone, luteinizing hormone, 25‐hydroxyvitamin D, lipid profile, and hemoglobin A1C (A1C) were measured. …”
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Decoding the synergistic potential of herbal medicine and dietary supplements for treating postmenopausal osteoporosis by Jinfang Dou, Xuehong Hu, Junchang Liu, Jiaxian Liu, Chuyue Zhang, Yuelin Zhang, Xianjie Zhen, Siyu Tao, Jinghua Zhang, Guangjian Jiang

“…The 12-week experiment involved measurements of bone density and microstructure, histological evaluation of femoral trabeculae and bone cortex, quantification of osteoclasts in the femur, assessment of osteoclast differentiation factor expression (NFATc1 and C-Fos), and measurement of collagen I carboxyl-terminal peptide (CTX-1). Additionally, intestinal flora analysis was performed. …”
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First Use of Superpulsed Fibre Thulium Laser-Based Contact Stone Ablation in Common Bile and Main Pancreatic Ducts by S. A. Budzinskiy, S. G. Shapovalyants, E. D. Fedorov, E. A. Vorobyeva, M. Yu. Svirin, M. G. Malyarov, P. L. Chernyakevich, E. N. Platonova

“…The first endoscopy stage comprised the encrusted pancreatic stent removal, retrograde pancreaticography, pancreatic ductotomy, narrowed terminal Wirsung’s duct bougienage with mechanical dilators and additional balloon-assisted dilation of the excision area and pancreatic stricture. …”
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Minute-cadence Observations of the LAMOST Fields with the TMTS. VI. Physical Parameters of Contact Binaries by Qiqi Xia, Xiaofeng Wang, Kai Li, Xiang Gao, Fangzhou Guo, Jie Lin, Cheng Liu, Jun Mo, Haowei Peng, Qichun Liu, Gaobo Xi, Shengyu Yan, Xiaojun Jiang, Jicheng Zhang, Cui-Ying Song, Jianrong Shi, Xiaoran Ma, Danfeng Xiang, Wenxiong Li

“…In J0132, both components are in the main sequence, whereas both components of J0913 lie above the terminal-age main sequence. Based on the relationship between orbital angular momentum and total mass for these two systems, as well as their low fill-out factors, it is possible that these two systems are newly formed contact binaries, having recently evolved from the detached configuration.…”
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Container Relocation and Retrieval Tradeoffs Minimizing Schedule Deviations and Relocations by Robert Klar, Anders Andersson, Anna Fredriksson, Vangelis Angelakis

“…In this context, port terminal storage yard operation is key, since complexity and poor coordination lead to containers stacked without consideration of retrieval schedules, resulting in time- and energy-consuming reshuffling operations. …”
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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats by Hong Yang, Cheng Zhang, Woonghee Kim, Mengnan Shi, Metin Kiliclioglu, Cemil Bayram, Ismail Bolar, Özlem Özdemir Tozlu, Cem Baba, Nursena Yuksel, Serkan Yildirim, Shazia Iqbal, Jihad Sebhaoui, Ahmet Hacımuftuoglu, Matthias Uhlen, Jan Boren, Hasan Turkez, Adil Mardinoglu

“…Excessive consumption of sucrose, in the form of sugar-sweetened beverages, has been implicated in the pathogenesis of metabolic dysfunction‐associated fatty liver disease (MAFLD) and other related metabolic syndromes. The c-Jun N-terminal kinase (JNK) pathway plays a crucial role in response to dietary stressors, and it was demonstrated that the inhibition of the JNK pathway could potentially be used in the treatment of MAFLD. …”
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Host protein PRPS2 interact with the non-structural protein p17 of Avian Reovirus and promote viral replication by Hu Xiaomiao, Zhao Ruihong, Li Wei, Pan Xiaocheng, Dai Yin, Wu Huimin, Wu Yantao, Zhang Chengcheng

“…Moreover, our findings demonstrate that the C-terminal region of PRPS2 is responsible for its binding to the p17 protein. …”
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Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Eff... by Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

“…Inactivated multidrug-resistant RT (RT1.14opt-in) was N-terminally fused to the signal providing secretion of NS1 protein of TBEV (Ld) generating optimized inactivated Ld-carrying enzyme RT1.14oil. …”
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Unveiling risk factors: a prognostic model of frequent peritonitis in peritoneal dialysis patients by Qi-jiang Xu, Qi-jiang Xu, Zhi-yun Zang, Xue-li Zhou, Xue-li Zhou, Ni-ya Ma, Li Pu, Li Pu, Zi Li

“…In the training set, we found several independent risk factors significantly associated with frequent episodes in PDAP patients, including diabetes mellitus (DM), hemoglobin (HB), serum albumin (ALB), lactatic dehydrogenase (LDH), serum potassium (K), N-terminal pro-brain natriuretic peptide (NT-proBNP) and peritoneal dialysate white cell counts on day 1. …”
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Lactoferrin: a secret weapon in the war against pathogenic bacteria by Lucero Ruiz-Mazón, Gerardo Ramírez-Rico, Mireya de la Garza

“…Moreover, cleavage of the Lf molecule could promote the production of lactoferricins (Lfcins) and lactoferrampin (Lfampin) from the N-terminal end, which are known to often have stronger antimicrobial effects than the native molecule, as well as analogous peptides, such as HLopt2, which have also shown enhanced antimicrobial activity. …”
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Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications by Tian-Hang Yu, Yan-Yu Ding, Yan-Yu Ding, Si-Guo Zhao, Jie-Hui Zhao, Yu Gu, Dong-Hui Chen, Fang Zhang, Wen-Ming Hong, Wen-Ming Hong

“…DAPK1, serving as a marker gene for the terminal subpopulation, exhibited an association with poor prognosis.ConclusionsDAPK1-based prognostic models show promise for accurately predicting outcomes in glioblastoma and glioma. …”
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The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages by Hwa-Jin Chung, Wonil Koh, Won Kyung Kim, Joon-Shik Shin, Jinho Lee, Sang Kook Lee, In-Hyuk Ha

“…Three mechanisms explaining the effects of Shinbaro3 in RAW 264.7 cells were identified as follows: (1) inhibition of the extracellular signal-regulated kinase 1 and 2 (ERK1/2), stress-activated protein kinase (SAPK)/c-Jun N-terminal protein kinase (JNK), and p38 mitogen-activated protein kinase (MAPK) pathways; (2) suppression of IκB kinase-α/β (IKK-α/β) phosphorylation and nuclear factor-kappa B (NF-κB) subunits in the NF-κB pathway, which are involved in MyD88-dependent signalling; and (3) downregulation of IFN-β mRNA expression via inhibition of interferon regulatory factor 3 (IRF3) and Janus-activated kinase 1 (JAK1)/signal transducer and activator of transcription 1 (STAT1) phosphorylation, which is involved in TRIF-dependent signalling. …”
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Modern modes of chronic hepatitis B treatment in daily clinical practice by M. V. Mayevskaya, M. A. Morozova, S. A. Ondos, V. T. Ivashkin

“…This article reviews in brief up-to-date modes of CHB treatment, clinical case demonstrating the basic AVT stages is presented: decision-making on its onset, monitoring of the patient during treatment, rules of choice and substitution of antiviral agents, criteria of treatment response assessment and indications for its termination.Conclusion. The adequate choice of drug at definition of antiviral treatment approach allows to suppress virus replication effectively, reduces risk of resistance development and rate of side effects while violation of international standards can result in fatal outcome. …”
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Modeling of Measuring Transducers for Relay Protection Systems of Electrical Installations by Iliya Iliev, Andrey Kryukov, Konstantin Suslov, Nikolay Kodolov, Aleksandr Kryukov, Ivan Beloev, Yulia Valeeva

“…Based on the results of calculating the complexes of currents and voltages at the MT terminals, parametric identification of the power transmission line was performed. …”
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Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration by Andrea Barragán-Cárdenas, Daniel Castellar-Almonacid, Yerly Vargas-Casanova, Claudia Parra-Giraldo, Adriana Umaña-Pérez, Joel López-Meza, Zuly Rivera-Monroy, Javier García-Castañeda

“…On the other hand, addition of the RGD sequence to the palindromic peptide in the N-terminal end resulted in a greater cytotoxic effect against cell lines derived from the three mainly diagnosed breast cancer molecular subtypes. …”
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