Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk. by Md Morshedur Rahman, Naim Siddique, Soharth Hasnat, Md Tanvir Rahman, Mustafizur Rahman, Munirul Alam, Ziban Chandra Das, Tofazzal Islam, M Nazmul Hoque

“…The observed bacteriocin, particularly bovicin, demonstrated the ability to disrupt the function of an essential protein, Rho factor of mastitis pathogens by blocking transcription termination process. Taken together, our in-depth genomic analysis underscores the metabolic versatility, safety profile, and antimicrobial potential of P. pentosaceus MBBL6, suggesting its promise for applications in therapeutics, bioremediation, and biopreservation.…”
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Expression of a Secretory Protein C1qTNF6, a C1qTNF Family Member, in Hepatocellular Carcinoma by Tamotsu Takeuchi, Yoshihiro Adachi, Tomoko Nagayama

“…Eukaryotic recombinant C1qTNF6 increased the level of active phosphorylated Akt molecules in cultured vascular endothelial cells via its C-terminal C1q domain. In the xenograft assay, enforced expression of C1qTNF6 markedly reduced the central hypovascular necrosis areas of the transplanted HepG2 hepatocellular carcinoma cells. …”
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Vitamin B6 Deficiency Induces Autism-Like Behaviors in Rats by Regulating mTOR-Mediated Autophagy in the Hippocampus by Lijuan Chen, Jing Li, Xinglian Liu, Zhiwei Zhao, Yan Jin, Yikun Fu, Aiqin Zhou, Chengqun Wang, Yan Zhou

“…The role of VB6 in the autophagy and apoptosis of cells was determined via Western blot and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL). …”
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The road ahead: emerging therapies for primary IgA nephropathy by Edward J. Filippone, Rakesh Gulati, John L. Farber

“…The factor B inhibitor iptacopan has conditional approval. The terminal pathway inhibitors cemdisiran and ravulizumab show promise in phase 2 studies. …”
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Intelligent Controller Design and Fault Prediction Using Machine Learning Model by Kailash Kumar, Suyog Vinayak Pande, T. Ch. Anil Kumar, Parvesh Saini, Abhay Chaturvedi, Pundru Chandra Shaker Reddy, Krishna Bikram Shah

“…Transient stability issues in a contemporary electrical power system represent one of the difficult tasks for an electrical engineer due to the rise in uncertain renewable energy sources (RESs) as a result of the need for green energy. The potential for terminal voltage to be adversely impacted by this greater RES raises the possibility of electrical device damage. …”
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Manajemen nyeri dengan virtual reality therapy pada pasien kanker : studi kasus by Lindasari Pradita Putri, Akhmad Mustofa

“…Nyeri yang terus menerus yang dirasakan oleh pasien-pasien penyakit terminal ini bisa mengurangi kualitas hidup dan fungsi fisik, meningkatkan level kelelahan dan mengganggu aktivitas sehari-hari  dan  sosial. …”
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Planning for success but facing uncertainty: lessons learned from a native oyster, Ostrea lurida, restoration project in the Salish Sea by James T. McArdle, Julie S. Barber, Sarah K. Grossman, Lindy L. Hunter

“…Low survival and recruitment do not necessitate termination of projects. However, these measurements do suggest that projects like ours need to consider expanding use of conservation aquaculture as a tool or employing adaptive management by developing and implementing novel strategies to increase naturally-occurring adult populations and available habitat.…”
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Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). by Christina Kronberger, Roya Anahita Mousavi, Begüm Öztürk, Robin Willixhofer, Theresa-Marie Dachs, René Rettl, Luciana Camuz-Ligios, Nima Rassoulpour, Christoph Krall, Brigitte Litschauer, Roza Badr Eslam

“…<h4>Methods</h4>We evaluated 106 PH patients with the 1-min-STST and 6MWT and measured cardiorespiratory parameters (heart rate, blood pressure, oxygen saturation) before and after test conduction. N-terminal pro brain-type natriuretic peptide (NT-proBNP), WHO functional class (WHO-FC) and mean pulmonary artery pressure (mPAP) were defined as markers of PH severity.…”
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Evaluating the Efficacy and Safety of Hepatitis E Vaccination in Reproductive-Age Women: A Systematic Review and Meta-Analysis by Vaidas Jotautis, Antigoni Sarantaki

“…HEV239 demonstrated high efficacy in preventing hepatitis E infection, with no significant increase in adverse pregnancy outcomes such as stillbirth or elective termination. However, there was an elevated risk of miscarriage (odds ratio [OR], 1.60; 95% confidence interval [CI], 0.99–2.57). …”
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Effects of Teenage Pregnancy on School Girl Education in Primary Schools in Katuna Town Council Kabale District. by Tumwebaze, Costance

“…On the impact of early pregnancy on life opportunities for young girls, it was found that 86 percent of participants had terminated their education. The study recommended that teenagers should be given career development which will assist them make appropriate changes from dependence to financial independence. …”
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Identification of heat tolerant lentil genotypes through stress tolerance indices by Rohit Sarkar, Gyan Prakash Mishra, Premakumar, Ankita Singh, Jenia Roy, Kumbarahally Murthigowda Shivaprasad, Shashidhar B. Reddappa, Sudhir Kumar, Ruchi Bansal, Uttarayan Dasgupta, Soma Gupta, Susheel Kumar Sarkar, Sanjeev Gupta, Shiv Kumar, Harsh K. Dikshit, Prachi Sripathrao Yadav, Muraleedhar S. Aski

“…Abstract With climate change projections indicating an increase in the frequency of extreme heat events and irregular rainfall patterns globally, the threat to global food security looms large. Terminal heat stress, which occurs during the critical reproductive stage, significantly limits lentil productivity. …”
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Effect of Denosumab on Bone Mineral Density of Hematopoietic Stem Cell Transplantation Recipients by Chaiho Jeong, Hee-Je Kim, Seok Lee, Moo Il Kang, Jeonghoon Ha

“…The bone turnover marker serum cross-linked C-terminal telopeptide of type 1 collagen was decreased at 18 months (−51.6 ± 17.6%, p<0.001). …”
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Treatment of limb skin defect with self-made skin distractor by Gao Lei, Li Kai, Zhang Yanlong, Wang Hongrun, Liu Shibo, Wang Yong, Peng Aqin

“…No skin stretch was terminated due to pain. All wounds were healed. The elasticity and color of the skin on the wound surface were not different from the surrounding skin. …”
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Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential by Valentina Sesti, Arianna Magni, Matteo Moschetta, Chiara Florindi, Marlene E. Pfeffer, Mattia Lorenzo DiFrancesco, Michele Guizzardi, Giulia Folpini, Luca Sala, Alessandra Gilda Ritacca, Beatrice Campanelli, Paola Moretti, Giuseppe Maria Paternò, Luca Maragliano, Matteo Tommasini, Francesco Lodola, Elisabetta Colombo, Fabio Benfenati, Chiara Bertarelli, Guglielmo Lanzani

“…Low-intensity optical stimulation with these modulators could influence cardiac electrical activity, demonstrating potential efficacy in destabilizing and terminating cardiac arrhythmias. We anticipate the MTs approach to find applications in neuroscience, biomedicine, and biophotonics, providing a tool for modulating cell physiology without genetic interventions.…”
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Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

“…The gene is flanked by two long terminal repeats (LTRs) and proximate to an origin of DNA replication (autonomously replicating sequence, ARS), which likely promote rapid GAP1 CNV formation. …”
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γ-Aminobutyric acid alleviates litchi thaumatin-like protein-induced inflammation and reduces gut microbial translocation by Yao Wang, Dongwei Wang, Kai Wang, Min Zhao, Cizhou Li, Yu Wang, Xuwei Liu, Lei Zhao, Zhuoyan Hu

“…In vitro study showed GABA could effectively regulate the level of inflammatory cytokines (interleukin (IL)-1β, IL-6, IL-10, and prostaglandin E2) and Ca2+ in cells, and inhibit the phosphorylation of p65, I κB, p38, c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK). …”
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The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis by Qin Qi, Rui Zhong, Yan Huang, Yong Tang, Xiao-wen Zhang, Chang Liu, Chun-fang Gao, Lin Zhou, Jian Yu, Lu-yi Wu

“…Mechanistically, our data revealed that PKM2, a terminal enzyme in the glycolytic pathway, is a downstream target of NSUN2-mediated m5C modification. …”
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Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency by V. S. Scherbakha, O. Z. Okhlobystina, A. V. Korolev, O. S. Shifrin, A. V. Stepanov, A. S. Tertychny, A. V. Okhlobystin, V. T. Ivashkin

“…Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. …”
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Anatomical and physiological features of the right heart affecting the effectiveness of balloon valvuloplasty and increase the risk of repeated interventions in children with valvu... by Yu.L. Kuzmenko, A.A. Dovhaliuk, M.P. Radchenko, O.О. Motrechko

“…The pronounced hypoplasia of the right ventricle and tricuspid valve, the amount of atrial interconnection and the low level of saturation after the termination of the functioning of the open arterial duct in the postoperative period are factors significantly increasing the need for interventions to optimize pulmonary flow in newborns.…”
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Interpreting Variants of Uncertain Significance in PCD: Abnormal Splicing Caused by a Missense Variant of DNAAF3 by Haixia Zheng, Chongsheng Cheng, Miao He, Wangji Zhou, Yixuan Li, Jinrong Dai, Ting Zhang, Kai‐Feng Xu, Xue Zhang, Xinlun Tian, Yaping Liu

“…Results We identified two variants of DNAAF3: c.557G>A, p.G186E in exon 5, and c.1364G>A, p.G455D at the terminal nucleotide of exon 10 in a 16‐year‐old male patient. …”
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