Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria by Marek Ussowicz, Dawid Przystupski, Patrycja Mensah-Glanowska, Agnieszka Piekarska

“…Non-transplant PNH therapies include anti-C5 monoclonal antibodies that reduce terminal complement activation (eculizumab, ravulizumab, and crovalimab) and proximal complement pathway inhibitors such as pegcetacoplan (C3 inhibitor), iptacopan (complement factor B inhibitor), and danicopan (complement factor D inhibitor). …”
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Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems by Teodosio Giacolini, Antonio Alcaro, David Conversi, Lorenzo Tarsitani

“…Depression is an evolutionarily conserved mechanism in mammals to terminate both separation anxiety, so as to protect the vulnerable social brain from the consequences of prolonged separation anxiety, and the stress of social competition when social defeat is predictable. …”
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Levistolide A and periplogenin inhibit the growth of gastric cancer cells in vitro and in vivo by Jia Li Guo, Hong Mei Hu, Shao Chin Lee, Ji Zhong Zhao

“…Apoptosis was detected by western blot to detect the cleavage of caspase substrate poly (ADP-ribose) polymerase (PARP) and terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate (dUTP) nick-end labelling (TUNEL) assays. …”
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Comparison of three- and six-component scoring models for predicting the futility in cancer resuscitation: a retrospective study by A. Pramono, N. Maryani

“… INTRODUCTION: Palliative care is an approach to managing patients with critical illnesses who require the support of organ function from failure, in addition to those with chronic and terminal diseases including cancer that cannot be cured until rehabilitation. …”
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Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells by Nidhi Varshney, Siddharth Singh, Meenakshi Kandpal, Vaishali Saini, Erle S. Roberston, Hem Chandra Jha

“…We reveal that AURKA overexpression and EBV infection induce aneuploidy in gastric epithelial cells. The AURKA (S89) N-terminal residue is critical for the centrosome maturation process in EBV-infected gastric epithelial cells. …”
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The impact of life events and transitions on physical activity: A scoping review. by Hannes Gropper, Jannika M John, Gorden Sudeck, Ansgar Thiel

“…For well-timed and successful PA interventions, it is important to understand when and why individuals take up or terminate PA.<h4>Objectives</h4>This scoping review aims to examine the extent, range, and nature of research on the impact of life events and transitions on PA and to summarize key findings.…”
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Congenital malformations in children of epileptic pregnant women in the Cienfuegos province (2008-2018) by María Soledad Vilches León, Carmen Niurka Piña Loyola, Maylé Santos Solís, Vivian Rosa Vázquez Martínez, Cristóbal Jorge Torres González, Niurys Gonzales Cano

“…The history of genetic termination of pregnancy was statistically significant (p= 0.006) and increased the risk of having a malformation 16 times. …”
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The role of music performance anxiety in musical training: four personal histories by Oscar Casanova, María Elena Riaño, Francisco Javier Zarza-Alzugaray, Santos Orejudo

“…Two of four respondents decided to terminate their music training before entering university level. …”
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Genome-wide quantification of polycistronic transcription in Leishmania major by Janne Grünebast, Stephan Lorenzen, Joachim Clos

“…Our work sheds light on the initiation, elongation, and termination of transcription, maps unidirectional, polycistronic transcription units, provides evidence for transcriptional pausing at or near starting points of RNA synthesis, and quantifies the varying transcription rates of the polycistronic transcription units. …”
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Tumor del estroma gastrointestinal by Rene Santiago Borges Sandrino, Dioslan Moreno Ruiz, Enia Ramón Musibay, Wilfredo Ernesto Santiesteban Pupo

“…Se encuentra durante la laparotomía tumor de 14 por 20 centímetros que compromete la luz del intestino delgado, se decide realizar extracción del tumor y anastomosis término terminal convencional. El paciente fue egresado a los ocho días con evolución favorable y pendiente de resultado anatomopatológico, el cual informó tumor del estroma gastrointestinal. …”
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Effect of exogenous progesterone and gonadotropin-releasing hormone application on maintenance of pregnancy in early pregnant ewes after prostaglandin f2 alpha injection by Mehmet Köse, Mehmet Salih Kaya, Mehmet Osman Atlı

“…While all pregnancies were terminated in PGF2&#945; group by day 25, P4 prevented pregnancy loss in PGF2&#945; + P4 + GnRH group (P<0.02). …”
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Acceso venoso para hemodiálisis y repercusión crónica en el sistema cardiovascular by Blanca Caridad Piedra Herrera, Yanet Acosta Piedra

“…En el tratamiento de enfermos renales en fase terminal, se realizan accesos vasculares para hemodiálisis. …”
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Welfare of horses during killing for purposes other than slaughter by EFSA AHAW Panel (EFSA Panel on Animal Health and Welfare), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dorea, Jordi Figuerola, Mette Herskin, Miguel Angel Miranda Chueca, Eleonora Nannoni, Romolo Nonno, Anja Riber, Karl Stahl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Mohan Raj, Antonio Velarde, Denise Candiani, Yves Van der Stede, Virginie Michel

“…Abstract Horses of different ages may have to be killed on‐farm for purposes other than slaughter (where slaughter is defined as killing for human consumption) either individually (i.e. on‐farm killing of unproductive, injured or terminally ill animals) or on a large‐scale (i.e. depopulation for disease control purposes and other situations, such as environmental contamination, disaster management, etc.). …”
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The Dutch version of the Dignity Therapy Question Protocol for individual Dutch nursing home residents without cognitive impairments (during COVID-19): a pilot study by Herman van Dammen, Kris Vissers, Gert-Jan van der Putten, Yvonne Engels

“…The mean number of words in the legacy document was 1078 words, which appeared shorter than in a community-based hospice setting or patients with metastatic cancer or terminally ill people. The reading aloud was much appreciated and was an emotional experience for some. …”
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Two Cases of Severe Hypertension in JAK2 Mutation-Positive Myeloproliferative Neoplasms by Raunak Rao, Spoorthy Kulkarni, Ian B. Wilkinson

“…Myeloproliferative neoplasms are a heterogeneous group of disorders resulting from the abnormal proliferation of one or more terminal myeloid cells—established complications include thrombosis and haemorrhagic events; however, there is limited evidence to suggest an association with arterial hypertension. …”
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Immunoinformatics design of a novel multiepitope vaccine candidate against non-typhoidal salmonellosis caused by Salmonella Kentucky using outer membrane proteins A, C, and F. by Elayoni E Igomu, Paul H Mamman, Jibril Adamu, Maryam Muhammad, Abubarkar O Woziri, Manasa Y Sugun, John A Benshak, Kingsley C Anyika, Rhoda Sam-Gyang, David O Ehizibolo

“…Typhimurium was included at the N-terminal. The resulting MEV construct demonstrated high structural quality and favorable physicochemical properties. …”
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Genes of Inflammation and Placental Function GWAS Associated with Idiopathic Recurrent Miscarriage in the Kazakh Population by Alexandra Murtazaliyeva, Gulnara Svyatova, Galina Berezina, Gulfairuz Urazbayeva, Aigerim Sadyrbekova

“…Conclusion: Significant associations of APOC3 gene genotypes with the development of iRM in the Kazakh population indicate the involvement of the placental system, which is realised by vascularisation defects and defective embryo implantation and leads to early pregnancy termination.…”
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Predictive Value of Soluble Growth Stimulator Gene 2 Protein for Coronary Slow Flow/No-Reflow in ST-Elevation Myocardial Infarction Patients Receiving Percutaneous Coronary Interve... by Shu-min Chang, Yan-tan Yu, Bo Luan, Ai-jie Hou, Yong Wang

“…Statistically significant differences (P<0.05) were observed in age, diabetes mellitus, sST2 level, neutrophil-to-lymphocyte ratio (NLR), fasting blood sugar, preprocedural blood pressure, intraprocedural hypotension, N-terminal pro-B-type natriuretic peptide, MB isoenzyme of creatine kinase (CK-MB), and cardiac troponin I (cTNI). …”
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The Use of Perovskia abrotanoides Extract in Ameliorating Heat Stress-Induced Oxidative Damage and Improving Growth Efficiency in Carp Juveniles (Cyprinus carpio) by Hossein Adineh, Saeed Zahedi, Morteza Yousefi, Zeynab Sedaghat, Sevdan Yilmaz, Ebrahim Gholamalipour Alamdari, Mohammad Farhangi

“…The experiment continued for 60 days. At the termination of the experiment, the mean final weight, weight gain percentage (WG%), feed conversion rate (FCR), and specific growth rate (SGR) have been improved significantly in all fish groups fed PAE-based diets with regard to those fed the reference diets. …”
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Interactive effects of salinity, redox, and colloids on greenhouse gas production and carbon mobility in coastal wetland soils. by Nicholas D Ward, Madison Bowe, Katherine A Muller, Xingyuan Chen, Qian Zhao, Rosalie Chu, Zezhen Cheng, Thomas W Wietsma, Ravi K Kukkadapu

“…This study examines how GHG production and organic matter (OM) mobility in coastal wetland soils vary with the availability of oxygen and other terminal electron acceptors. We also evaluated how OM and redox-sensitive species varied across different size fractions: particulates (0.45-1μm), fine colloids (0.1-0.45μm), and nano particulates plus truly soluble (<0.1μm; NP+S) during 21-day aerobic and anaerobic slurry incubations. …”
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