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2321
Türkiye’deki Havalimanlarının Veri Zarflama Analizi ve Malmquist Toplam Faktör Verimliliği Endeksleri İle Finansal Etkinliklerinin Analizi
Published 2019-08-01“…Analizde çalışan sayısı, işletme gideri, terminal alanı m2 , pist sayısı ve apron sayısı olmak üzere beş adet girdi değeri belirlenmiştir. …”
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2322
Dysregulation of Podocyte BK Channels and Nephrosis: Effects of Circulating Factors and Auxiliary β4 Subunits
Published 2024-12-01“…Podocytes express large-conductance Ca<sup>2+</sup>-activated K<sup>+</sup> channels (BK channels) and at least two different pore-forming KCa1.1 subunit C-terminal splice variants, known as VEDEC and EMVYR, along with auxiliary β and γ subunits. …”
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2323
Using the Sleeping Beauty Transposon System for Doxycycline-inducible Gene Expression in RAW264.7 Macrophage Cells to Study Phagocytosis
Published 2025-02-01“…In this protocol, we use the Sleeping Beauty transposon system to generate RAW264.7 cells with doxycycline-inducible inositol polyphosphate 4-phosphatase B containing a C-terminal CaaX motif (INPP4B-CaaX). INPP4B-CaaX dephosphorylates the D-4 position of phosphatidylinositol 3,4-bisphosphate and inhibits phagocytosis. …”
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2324
Cell Surface Proteins for Enrichment and In Vitro Characterization of Human Pluripotent Stem Cell-Derived Myogenic Progenitors
Published 2022-01-01“…Lastly, we showed that CD271 expression is essential for terminal differentiation of human PSC-derived myogenic progenitors. …”
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2325
The Effect of Tumor Angiogenesis Agents on Tumor Growth Dynamics: A Mathematical Model
Published 2025-01-01“…However, the increase of inhibitory factors of tumor angiogenesis agents leads to the termination of chaos. Conclusion: Our results show the ineffectiveness of targeted treatments on the immune system, which has been confirmed by many negative treatment methods in immunotherapies. …”
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2326
Combined PARP14 inhibition and PD-1 blockade promotes cytotoxic T cell quiescence and modulates macrophage polarization in relapsed melanoma
Published 2025-01-01“…Moreover, this combination mitigated the terminal exhaustion of cytotoxic T cells by inducing a quiescent state, thereby preserving functionality. …”
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2327
Polydatin ameliorates early brain injury after subarachnoid hemorrhage through up-regulating SIRT1 to suppress endoplasmic reticulum stress
Published 2024-09-01“…Western blot and quantitative real-time polymerase chain reaction (PCR) analyses were performed to examine protein and mRNA expressions related to ER stress. Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining was used to detect cell apoptosis, and transmission electron microscopy was used to observe the ultrastructure of the endoplasmic reticulum.ResultsThe results indicated that PD significantly reduced brain edema and Evans blue extravasation after SAH, improving neurological function. …”
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2328
Redes de apoyo: mejorando la efectividad escolar del CECYTEO Ixtlán, Sierra Norte, Oaxaca
Published 2024-12-01“…Resultados: Se analizaron indicadores de reprobación, eficiencia terminal y abandono escolar en cuatro ciclos escolares, del periodo 2018-2019 al 2021-2022. …”
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2329
Improving ecological water diversion process to promote oasis restoration using a monthly conceptual lumped ecohydrological model: A case study of the Qingtu Oasis, China
Published 2025-02-01“…Study focus: Improving the Ecological Water Diversion (EWD) process is crucial for promoting recovering terminal oases in arid inland basins. This research developed a Monthly Conceptual Lumped Ecohydrological Model (MCLEM) by integrating the surface water and groundwater balance, ecological response, and evapotranspiration equations. …”
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2330
Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene.
Published 2025-01-01“…Superposition of the two models reveal that the overall structural motifs are similarly aligned, except for the C-terminal peptides diverging between the A1 and A2 models, possibly explaining their functional difference. …”
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2331
Pathological effects of pregabalin toxicity in rats
Published 2024-01-01“…The main mechanism of action is binding at the alpha-2-delta site, which inhibits calcium influx in response to depolarization at nerve terminals and, in turn, suppresses the release of glutamate, noradrenaline, and substance P. …”
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2332
MAL-Net: Model-Adaptive Learned Network for Slow-Time Ambiguity Function Shaping
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2333
Prevalence Rates and an Evaluation of Reported Risk Factors for Osteonecrosis (Avascular Necrosis) in Crohn’s Disease
Published 2000-01-01“…In one patient, disease was confined to the colon, while three patients had disease involving the terminal ileum and colon. Disease behaviour in two patients was classified as penetrating because of concomitant ischiorectal abscesses, while one patient developed a metastatic colon carcinoma. …”
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2334
Expanding the Diversity of <i>Actinobacterial Tectiviridae</i>: A Novel Genus from <i>Microbacterium</i>
Published 2025-01-01“…The phages have linear dsDNA genomes 15,438–15,636 bp with 112–120 bp inverted terminal repeats. Transmission electron microscopy (TEM) imaging analysis revealed that the six novel phages have six-sided icosahedral double-layered capsids with an internal lipid membrane that occasionally forms protruding nanotubules. …”
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2335
Knockdown of PTEN promotes colon cancer progression and induces M2 macrophage polarization in the colon cancer cell environment
Published 2023-07-01“…The expressions of phosphate (p)-p38, c-Jun N-terminal kinase (JNK), activator protein 1 (AP-1), B-cell lymphoma-2 (Bcl-2) protein in colon cancer tissues and cells were significantly higher than in precancerous tissues or CCD-18Co cells (P-values < 0.05). …”
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2336
Тransplastomic tobacco plants producing the hydrophilic domain of the sheep pox virus coat protein L1R
Published 2020-12-01“…A vector containing a deletion variant of the SPPV_56 gene, which encodes the N-terminal hydrophilic part of the viral coat protein L1R, was constructed to transform tobacco plastids. …”
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2337
Lack of Clinically Meaningful Effect of Cariprazine on the Pharmacokinetics of a Combined Oral Contraceptive
Published 2024-12-01“…Results Overall, CAR had no clinically meaningful effect on the PK of the COC. The terminal half-life and the time of maximum plasma concentration of EE and LNG were not altered by CAR co-administration. …”
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2338
Hazardous geological processes at incomplete construction sites
Published 2023-10-01“…The purpose of the research is to study the regularities of development of hazardous geological processes caused by the termination of construction of buildings for a long time. …”
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2339
Cerebrovascular stenosis related to tyrosine kinase inhibitor for chronic myeloid leukemia: two illustrative cases
Published 2025-01-01“…Digital subtraction angiography revealed diffuse stenosis with luminal narrowing from the terminal portion of the internal carotid artery (ICA) to the entire M1 length of the middle cerebral artery (MCA). …”
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2340
Ionesco vs Papu: cronica unei empatii erodate (I)
Published 2014-12-01“…Initialement, causée par une poussée identique, due à la réaction envers l’état de marginalisation perçue, leur aventure intellectuelle se termine, après leur placement au centre des systèmes de référence incontigues (dans une situation, le champ littéraire français, dans l’autre, celui roumain), en proposant des solutions sensiblement différentes aux mêmes grandes interrogations, selon les exigences du climat culturel qui les maintient dans une captivité par défaut. …”
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