-
1061
Compilation and functional classification of telomere length-associated genes in humans and other animal species
Published 2023-06-01“…Telomeres are the terminal regions of chromosomes that ensure their stability while cell division. …”
Get full text
Article -
1062
Development of a method to achieve antegrade in situ fenestration of endovascular stent grafts in abdominal aortic aneurysms
Published 2025-02-01“…Abdominal aortic aneurysm (AAA) is the focal dilation of the terminal aorta, which can lead to rupture if left untreated. …”
Get full text
Article -
1063
From canonical to unique: extension of a lipophilicity scale of amino acids to non-standard residues
Published 2024-07-01“…To this end, we employed two structural models, Model 1 and 2, differentiated solely by their C-terminal capping groups using an N- or O-methyl substituent, respectively. …”
Get full text
Article -
1064
Predição da Propensão à Cardiopatia Atrial e Fibrilação Atrial Paroxística em Pacientes com Acidente Vascular Cerebral Embólico de Origem Indeterminada (ESUS)
Published 2025-01-01“…Em pacientes com cardiopatia atrial, foi realizada análise de regressão multivariável; velocidade de força terminal da onda P na derivação V (PTFV) > 5000 mV.ms, índice de volume do átrio esquerdo > 34 ml/m2 e fração de ejeção < 45% foram preditores independentes significativos de FA com valores de p significativos de 0,001, < 0,001 e 0,001, respectivamente. …”
Get full text
Article -
1065
Genetic variation of the nuclear sequences of mitochondrial origin associated with retrotransposon Tv1 insertions in Drosophila species of the virilis group
Published 2018-11-01“…A specific situation was revealed for D. montana, in which Tv1 insertions with nearly identical 5' and 3' long terminal repeats (LTRs) were present in accessions of flies from Europe and Asia. …”
Get full text
Article -
1066
Unveiling risk factors: a prognostic model of frequent peritonitis in peritoneal dialysis patients
Published 2025-01-01“…In the training set, we found several independent risk factors significantly associated with frequent episodes in PDAP patients, including diabetes mellitus (DM), hemoglobin (HB), serum albumin (ALB), lactatic dehydrogenase (LDH), serum potassium (K), N-terminal pro-brain natriuretic peptide (NT-proBNP) and peritoneal dialysate white cell counts on day 1. …”
Get full text
Article -
1067
JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL
Published 2020-01-01“…To explore the role of the c-Jun N-terminal kinase (JNK) signaling pathway in upregulated NGAL expression and its antiapoptotic mechanism in lipopolysaccharide (LPS)-mediated renal tubular epithelial cell injury. …”
Get full text
Article -
1068
Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications
Published 2025-01-01“…DAPK1, serving as a marker gene for the terminal subpopulation, exhibited an association with poor prognosis.ConclusionsDAPK1-based prognostic models show promise for accurately predicting outcomes in glioblastoma and glioma. …”
Get full text
Article -
1069
Application of Image Denoising Method Based on Two-Way Coupling Diffusion Equation in Public Security Forensics
Published 2021-01-01“…The system uses mobile phones as the video image capture terminal to solve the problem of rapid response and concealment and uses 5G communication technology as the transmission medium to solve the problem of device mobility and link maintenance. …”
Get full text
Article -
1070
The intervention of curcumin on rodent models of hepatic fibrosis: A systematic review and meta-analysis.
Published 2024-01-01“…The outcome indicators included liver cell structure and function related indicators, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin (ALB), ratio of albumin to globulin (A/G), total bilirubin (TBIL), bax protein, bcl-2 protein and index of liver, as well as the relevant indicators for evaluating the degree of hepatic fibrosis, such as hyaluronic acid (HA), laminin (LN), type I collagen (Collagen I), type III collagen (Collagen III), type III procollagen (PCIII), type III procollagen amino terminal peptide (PIIINP), type IV collagen (IV-C), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), α-Smooth muscle actin (α-SMA), hydroxyproline (HYP), platelet derived factor-BB (PDGF-BB), connective tissue growth factor (CTGF) and transforming growth factor-β1 (TGF-β1), and oxidative stress-related indicators, such as superoxide dismutase (SOD), malondialdehyde (MDA) and glutathione peroxidase (GSH-Px). …”
Get full text
Article -
1071
Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway
Published 2021-01-01“…Western blotting was used to analyze the expression of TGF-β2, Smad 2/3, phosphorylated Smad 2/3 (p-Smad 2/3), and α-smooth muscle actin (α-SMA). Terminal deoxynucleotidy1 transferase dUTP nick-end labelling (TUNEL) assay was performed on cryosections of mouse eyes to detect apoptosis. …”
Get full text
Article -
1072
Characterization of the First Marine Pestivirus, Phocoena Pestivirus (PhoPeV)
Published 2025-01-01“…Pestiviruses generally counteract the cellular innate immune response by degradation of interferon regulatory factor 3 (IRF3) mediated by the viral N-terminal protease (N<sup>pro</sup>). No degradation of IRF3 and an increased expression of the type 1 interferon-stimulated antiviral protein Mx1 was observed in porcine cells infected with PhoPeV whose genome lacks the N<sup>pro</sup> encoding region. …”
Get full text
Article -
1073
Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action
Published 2025-02-01“…These proteins come together to form a functional enzyme complex, where the C-terminal helix of each HslU subunit is inserted into the binding pocket of each HslV dimer. …”
Get full text
Article -
1074
The Value of P‐Wave Parameters Changes in Predicting Catheter Ablation Outcomes for Paroxysmal Atrial Fibrillation
Published 2025-01-01“…P‐wave amplitude (PWA) and P‐wave terminal force in V1 (PTFV1) Corrected P‐wave duration (PWDc), and P‐wave dispersion (PWDisp), were measured before and after ablation. …”
Get full text
Article -
1075
The Impact of Thyme and Rosemary on Prevention of Osteoporosis in Rats
Published 2019-01-01“…Blood samples were collected for different biochemical analyses in plasma (calcium (Ca), phosphorus (P), magnesium (Mg), tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP), malondialdehyde (MDA), parathyroid hormone (PTH), C-terminal telopeptide (CTX), and 1,25-(OH)2-vitamin D3). …”
Get full text
Article -
1076
A Bioclinical Pattern for the Early Diagnosis of Cardioembolic Stroke
Published 2014-01-01“…We aim to evaluate if plasma biomarkers can predict stroke subtypes in the early phase from stroke onset. Methods. Plasma N-terminal prohormone of brain natriuretic peptide (NT-proBNP), D-dimer, C-reactive protein, serum albumin, and globulin levels have been investigated in 114 consecutive patients presenting at the emergency room within 6 hours of the ischemic stroke onset. …”
Get full text
Article -
1077
Identification and characterization of mRNAs of receptor-like kinases MhyGSO1 and MhyGSO2 in flowering parasitic plant Monotropa hypopitys
Published 2017-05-01“…Structural analysis of the encoded amino acid sequences revealed conserved domains, specific for leucine-rich repeat receptor-like kinases, in MhyGSO1, and the N-terminal leucine-rich domain in MhyGSO2. Phylogenetic analysis of MhyGASSHOs confirmed their homology with GSO1 and GSO2 kinases of the Rosids and Asterids representatives. …”
Get full text
Article -
1078
Chemically Engineered GaN Thin Films for Light‐Stimulated Artificial Synapses
Published 2025-02-01“…Herein, a simple two‐terminal light‐stimulated synaptic device is fabricated using GaN thin films through metal‐organic chemical vapor deposition. …”
Get full text
Article -
1079
Comparative Efficacy and Safety of Targeted Therapies for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Network Meta-Analysis
Published 2021-01-01“…Bosentan was significantly better than others with regard to reducing brain natriuretic peptide/N-terminal pro-B-type natriuretic peptide with a probability of 84.3%. …”
Get full text
Article -
1080
Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype.
Published 2025-01-01“…These known rosetting PfEMP1 variants fall into two types, characterised by N-terminal domains known as "domain cassette" 11 (DC11) and DC16. …”
Get full text
Article