Research progress on the antiviral immune regulation of ubiquitin ligase F-box family by MENG Xiangbo, LI Tianqi, ZHANG Tong

“…Based on the secondary structure of the C-terminal, FBPs can be classified as FBXW, FBXL, and FBXO. …”
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B3LYP Study on Reduction Mechanisms from O2 to H2O at the Catalytic Sites of Fully Reduced and Mixed-Valence Bovine Cytochrome 𝑐 Oxidases by Yasunori Yoshioka, Masaki Mitani

“…This water molecule constructs the network of hydrogen bonds of Tyr244, farnesyl ethyl, and Thr316 that is a terminal residue of the K-pathway. It plays crucial roles for the proton transfer to the dioxygen to produce the water molecules in both MV and FR C𝑐Os. …”
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Investigating the Effect of Urban New Technologies on the Iranian Lorry Drivers’ Behavior by Abdolreza Sheikholeslami, Ehsan Ayazi, Ali Moghadari

“…Also, its influencing factors—in the group of driver characteristics, vehicle, and mileage—were obtained by using a demographic questionnaire, Driving Behavior Questionnaire (DBQ), and interviews with 420 drivers over 60 days at Tehran Terminal. After correcting incomplete questionnaires, 351 drivers’ information was used for statistical analysis. …”
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Plasma Membrane Targeting of Protocadherin 15 Is Regulated by the Golgi-Associated Chaperone Protein PIST by Hongyun Nie, Yueyue Liu, Xiaolei Yin, Huiren Cao, Yanfei Wang, Wei Xiong, Yushuang Lin, Zhigang Xu

“…The interaction is mediated by the PDZ domain of PIST and the C-terminal PDZ domain-binding interface (PBI) of PCDH15. …”
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Barriers and enablers encountered by bereaved informal motor neuron disease (MND) caregivers when trying to access bereavement support: a qualitative cross-sectional thematic analy... by Laura Cramond, Liberty Braben, Deepsi Khatiwada, Belinda F Bradley, Suresh K. Chhetri

“…Background Caregivers of people with motor neuron disease (MND) face more negative consequences of caregiving than other terminal illnesses. The impact of this caregiver burden can negatively influence bereavement outcomes.Objectives This study aims to explore the support needs of caregivers of people with MND, the types of bereavement services they use, or the reasons for not using bereavement services, and understanding the opportunities and barriers to accessing bereavement services.Design The design of the study was a qualitative interview study using thematic analysis following the method of Braun and Clarke (2006).Setting and participants Twenty bereaved caregivers of people with MND were purposively sampled. …”
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Synthesis and crystal structure of 5,10-bis(phenylsulfonyl)tetrahydrodibenzopentalene by Toshiki Sakami, Hikaru Watanabe, Takuma Sato, Yasuhiro Okuda, Kan Wakamatsu, Haruo Akashi, Akihiro Orita

“…The structure features a wide V-shaped motif consisting of 6–5–5–6 fused rings, with a dihedral angle of approximately 97.2° between the planes of the terminal phenylene rings. Additionally, a pair of phenylsulfonyl groups were observed at the exo positions relative to the V-shaped array.…”
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Characteristics of Patients With Community‐Acquired Pressure Injuries by Midori Nagano, Yoshiko Kubo, Akiko Egawa, Masayo Kobayashi, Masami Sato

“…Patients who were at ‘very high risk’ of having PI were characterised by incurring significant burden on caregivers and need of medical services that prospects terminal care.…”
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Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…Moreover, EEBC significantly reduced the number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive apoptotic cells increased by SCO treatment. …”
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Structure Characterization and Antioxidant Activity of a Novel Polysaccharide from <i>Bacillus natto</i> Fermented Millet Bran by Hanzhuo Zhang, Xia Fan, Wenjie Zhao, Fanqiang Meng, Fengxia Lu, Zhaoxin Lu, Haizhen Zhao

“…The monosaccharide composition, FT-IR, methylation, and NMR results indicated that FMBP-1 was only composed of glucose and was an α-(1→4)-D-glucan that branched at O-6 with a terminal 1-linked α-D-Glcp as a side chain. In addition, the antioxidant assays indicated that FMBP-1 possessed certain capacities for scavenging free radicals and reducing power, and this was in a concentration-dependent manner. …”
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A Novel Dual-Rotor Homopolar AC Machine by T. Ruekamnuaychok, J. Zhong, S. Sudhoff, R. Swanson, A. Sah, H. Singh, N. Aronhime, E. Schultz

“…The fundamental operating principles of the DHAM are explained, and its torque production and terminal characteristics are outlined. The permanent magnet version of the machine is shown to achieve an extended constant power speed range without impacting the PM field intensity, allowing the use of magnet materials with modest values of intrinsic coercive force. …”
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Detailed Nonlinear Modeling and High-Fidelity Parallel Simulation of MMC With Embedded Energy Storage for Wind Farm Grid Integration by Bingrong Shang, Ning Lin, Venkata Dinavahi

“…The proposed modeling and computing method is applied to a multi-terminal DC system with wind farms, and significant speedups over CPU-based simulation are achieved, with the accuracy validated by the offline simulation tool PSCAD.…”
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Speciation of heavy metals in coastal water of Qeshm Island in the Persian Gulf by A.R. Karbassi, S. Tajziehchi, H. Khoshgalb

“…The present study brings out the results of a project that was carried out to investigate the adverse effects of oil terminal on coastal waters of Qeshm Island and aims to elaborate on speciation of metals in coastal waters. …”
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La familia y la limitación del esfuerzo terapéutico en los cuidados intensivos pediátricos. Aspectos éticos by Ariel Efrén Uriarte Méndez, Jesús Vila Díaz, Yagén Pomares Pérez, Andrés Prieto Apesteguía, Jorge Luis Capote Padrón

“…Casi toda la literatura médica que trata este tema, se refiere al derecho del paciente y de la familia de limitar un esfuerzo terapéutico fútil y de lo acertado de esto para evitar el sufrimiento innecesario del enfermo; sin embargo, existe poca información acerca de cómo actuar ante situaciones en que los familiares de un niño en estadio terminal, insisten en continuar con tratamientos que no tendrán resultados y que solo provocarán dolor e incremento del sufrimiento, sin contar el gasto innecesario de recursos, lo cual pone al médico en una situación difícil. …”
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Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α by Ken Shirato, Kazuhiko Imaizumi

“…Moreover, LPS evoked similar levels of phosphorylation of c-Jun N-terminal kinase (JNK) and nuclear factor-κB (NF-κB) in young and middle-aged mice. …”
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Development of cell lines with increased susceptibility to diverse adeno-associated viral vectors to enable in vitro potency assays by James Zengel, Emma S. Esterman, Anitha Ponnuswami, Nicholas R. Wall, Jan E. Carette

“…For the latter, we utilized guide RNAs targeting the conserved AAV2 inverted terminal repeat (ITR) sequence present in most AAV transfer vectors. …”
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Two complementing in vivo selection systems based on CCA-trimming exonucleases as a tool to monitor, select and evaluate enzymatic features of tRNA nucleotidyltransferases by Karolin Wellner, Josefine Gnauck, Dorian Bernier, Stephan H. Bernhart, Heike Betat, Mario Mörl

“…Recently, we developed an in vivo screening system that allows for the selection and analysis of tRNA nucleotidyltransferase variants by challenging terminal AMP incorporation into tRNA during induced RNase T-catalyzed CCA-decay. …”
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A Single-Stage Isolated Battery Charger Using Nonbridged Positive Cuk Converter Configuration by Tanmay Shukla, N. P. Patidar, Apsara Adhikari

“…The usage of the Cuk converter garnishes the system with input and output inductances, which lessens supply current harmonic distortion and, thus supply terminal low pass filter requirement is eradicated. …”
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Reaction of the Liver upon Long-Term Treatment of Fluoxetine and Atorvastatin Compared with Alcohol in a Mouse Model by Zhiliang Chen, Tony C. H. Chow, Shicong Wang, Gigi C. T. Leung, Sharon L. Y. Wu, David T. Yew

“…Comparisons of animals treated with the three drugs were carried out: serum aspartate transaminase (AST), alanine transaminase (ALT), and albumin were measured; liver tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta (TGF beta-1) levels were evaluated; proliferative cells were detected via immunohistochemistry (IHC) targeting on proliferating cell nuclear antigen (PCNA) and minichromosome maintenance complex component 2 (MCM2); for apoptosis, IHC targeting on activated caspase-3 and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) were employed; and histopathology was also documented in all groups. …”
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Spatially Varying Relation between Built Environment and Station-Level Subway Passenger-Distance by Hongtai Yang, Zhihao Zhao, Chaozhe Jiang, Yi Wen, Malik Muneeb Abid

“…The accessibility of the station, station type, such as transfer or terminal, number of bus stops, number of restaurants, density of building area, density of the national road network, and density of the provincial road network, all have a positive correlation with SLPD. …”
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Synthesis and Anti-Inflammatory Activity of New Alkyl-Substituted Phthalimide 1H-1,2,3-Triazole Derivatives by Shalom Pôrto de Oliveira Assis, Moara Targino da Silva, Ronaldo Nascimento de Oliveira, Vera Lúcia de Menezes Lima

“…Four new 1,2,3-triazole phthalimide derivatives with a potent anti-inflammatory activity have been synthesized in the good yields by the 1,3-dipolar cycloaddition reaction from N-(azido-alkyl)phthalimides and terminal alkynes. The anti-inflammatory activity was determined by injecting carrageenan through the plantar tissue of the right hind paw of Swiss white mice to produce inflammation. …”
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