Neuronal Differentiation of Adipose Derived Stem Cells: Progress So Far by T. J. Moore, Heidi Abrahamse

“…In addition to substantial research already having been conducted on the in vitro differentiation of stem cells for the treatment of neurological repair, numerous strategies for the induction and culture of stem cells into terminal neural lineages have also been developed. …”
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Inflammation in Diabetic Nephropathy by Andy K. H. Lim, Gregory H. Tesch

“…Lastly, we present the latest data on the pathogenic role of the stress-activated protein kinases in diabetic nephropathy, from studies on the p38 mitogen activated protein kinase and the c-Jun amino terminal kinase cell signalling pathways. The genetic and pharmacological approaches which reduce inflammation in diabetic nephropathy have not only enhanced our understanding of the pathophysiology of the disease but shown promise as potential therapeutic strategies.…”
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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity by Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi

“…However, shedding or downregulation of NKG2D ligands (NKG2DL) can prevent NKG2D activation, resulting in escape of cancer cells from NKG2D-dependent immune surveillance.Methods To enable tumor-specific targeting of NKG2D-expressing effector cells independent of membrane-anchored NKG2DLs, we generated a homodimeric recombinant antibody which harbors an N-terminal single-chain fragment variable (scFv) antibody domain for binding to NKG2D, linked via a human IgG4 Fc region to a second C-terminal scFv antibody domain for recognition of the tumor-associated antigen ErbB2 (HER2). …”
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Decreased sirtuin 1 in type 2 diabetes patients with abnormal BMD by Yao Xu, Tianxiao Hu, Peiwu Jiang, Xiujing Wang, Jiaqi Yao, Huiling Shen, Zhenying Zhang, Bojing Zheng, Ting Wang, Yanxia Ren, Jing Wang, Qingying Tan

“…Serum Sirtuin 1 levels and bone turnover markers, including osteocalcin (OC), procollagen type 1 N-terminal propeptide (P1NP), and β-C-terminal telopeptide of type I collagen (β-CTX), were measured using enzyme-linked immunosorbent assay (ELISA). …”
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PINK1 modulates Prdx2 to reduce lipotoxicity‐induced apoptosis and attenuate cardiac dysfunction in heart failure mice with a preserved ejection fraction by Hao Zhang, Tianyu Xu, Xiyuan Mei, Qiming Zhao, Qiling Yang, Xianghui Zeng, Zhuang Ma, Haobin Zhou, Qingchun Zeng, Dingli Xu, Hao Ren

“…In vitro, an interaction between the N‐terminal region (amino acids 1–133) of PINK1 and Prdx2 was identified. …”
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Development of Low Energy Gap and Fully Regioregular Polythienylenevinylene Derivative by Tanya M. S. David, Cheng Zhang, Sam-Shajing Sun

“…This paper will first briefly review this type of polymers and also report synthesis and characterization of a specific example new polymer, a low energy gap, fully regioregular, terminal functionalized, and processable conjugated polymer poly-(3-dodecyloxy-2,5-thienylene vinylene) or PDDTV. …”
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Design and Fabrication of Flexible Nanoantenna-Based Sensor Using Graphene-Coated Carbon Cloth by Senthil Kumar Kandasamy, S. Maheswaran, S. Anbu Karuppusamy, J. Indra, R. Anand, P. Rega, A. Kavitha, K. Immanuvel Arokia James, Kasthuri Nehru, K. Kathiresan

“…In this work, a 5 GHz graphene nanoantenna that falls inside the very-small-aperture terminal (VSAT) C-band range has been fabricated. A graphene substrate with a thickness of h = 0.5 cm is formed which is then used for fabricating a graphene nanoantenna working at 5 GHz. …”
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Inflammatory Myofibroblastic Tumor of the Bladder: 2 Rare Cases Managed with Laparoscopic Partial Cystectomy by Sofia Santos Lopes, Andrea Furtado, Rita Oliveira, Ana Cebola, Bruno Graça, Manuel Ferreira Coelho, Fernando Ferrito, Carrasquinho Gomes

“…Both patients were male and presented with macroscopic hematuria; in the first case terminal hematuria was associated with irritative voiding symptoms. …”
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Reflections on the current context and assessment of undergraduate medical education in Brazil by GERSON ALVES PEREIRA JÚNIOR, RAMIRO COLLEONI NETO, ROSANA ALVES, HERMILA TAVARES VILAR GUEDES, JORGE CARVALHO GUEDES, PEDRO TADAO HAMAMOTO FILHO, JOSÉ EDUARDO LUTAIF DOLCI, CESAR EDUARDO FERNANDES

“…The second part discusses the possibilities of evaluating medical training, which is terminal in Brazil, enabling the newly graduated physician to claim the professional registration and to practice medicine, being evaluated only by their own medical course. …”
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Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway by Chao Chen, Qiwu Wang, Jiwen Liu

“…Methods CRPC cells were treated with curcumin and their viability was assessed by MTT assay and apoptosis was detected by annexinV/propidium iodide double-staining and terminal deoxynucleotidyl transferase dUTP nick-end labeling assays. …”
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Voltage Profile Analysis in Smart Grids Using Online Estimation Algorithm by P. Raghavendra, Ramakrishna S. S. Nuvvula, Polamarasetty P. Kumar, Dattatraya N. Gaonkar, A. Sathoshakumar, Baseem Khan

“…An algorithm is developed for voltage profile estimation using real-time sensor remote terminal unit (RTU) which takes into account topological characteristics, such as radial structure and high R/X ratio, of the smart distribution grid with DG systems. …”
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Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats by Marcel Irintchev, Orlando Guntinas-Lichius, Andrey Irintchev

“…Although BDNF also reduced cholinergic terminal loss at 1 week, it had no effect on this parameter at two months and no effect on functional recovery. …”
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Blockchain-Based Secure Traceable Scheme for Food Supply Chain by S. Thangamayan, Kalyani Pradhan, Ganesh Babu Loganathan, S. Sitender, S. Sivamani, Mulugeta Tesema

“…We can witness a series of detailed insights into food from the manufacturing source to the consumption terminal. A blockchain-based food tracking system is created as a solution to these issues. …”
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Epigenetic Drug Interventions in Breast Cancer: A Narrative Review of Current Research and Future Directions by Sarah Bibi Mungly, Evelyn Priya Peter, Ling-Wei Hii, Chun-Wai Mai, Felicia Fei-Lei Chung

“…With renewed interest in epigenetic-modifying pharmaceutical agents, namely DNA methyltransferase inhibitors (DNMTi), histone deacetylase inhibitors (HDACi), bromodomain and extra-terminal inhibitors (BETi), and enhancer of zeste homolog 2 inhibitors (EZH2i), there have been extensive preclinical and clinical studies to evaluate the safety and efficacy of these agents as potential treatments for breast cancer. …”
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Biophysical and Structural Studies on the Capsid Protein of the Human Immunodeficiency Virus Type 1: A New Drug Target? by José L. Neira

“…It is caused by a retrovirus, HIV, whose mature capsid (enclosing the RNA with other proteins) is formed by the assembly of several hundred copies of a protein, CA*. The C-terminal domain of such protein, CAC, is a driving force in virus assembly and the connections in the mature capsid lattice indicate that CAC joins through homodimerization of the CA hexamers. …”
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Relationship between functional structures and horizontal connections in macaque inferior temporal cortex by Danling Hu, Takayuki Sato, Kathleen S. Rockland, Manabu Tanifuji, Hisashi Tanigawa

“…While some axon terminal patches shared responsiveness to specific visual features with the injection site, many connected to regions with different selectivity. …”
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Optimal Design of Cooperative Penetration Trajectories for Multiaircraft by Qiangqiang Xu, Jianquan Ge, Tao Yang

“…The impact time and angle constraints are given, and the virtual target point is introduced for terminal guidance. Two cases are simulated and verified. …”
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Conditional Inactivation of HIF-1 Using Intrabodies by Arjan J. Groot, Eelke H. Gort, Elsken van der Wall, Paul J. van Diest, Marc Vooijs

“…Here we provide a novel approach for HIF-1 targeted therapy using single-domain llama antibodies directed against the HIF-1α oxygen dependent degradation domain which encompass the N-terminal transactivation domain. Conditional expression of HIF intrabodies in mammalian cells interfered with binding to pVHL and inhibited hypoxia induced activation of endogenous target genes. …”
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Fungi inhabiting attine ant colonies: reassessment of the genus Escovopsis and description of Luteomyces and Sympodiorosea gens. nov. by Quimi Vidaurre Montoya, Maria Jesus Sutta Martiarena, Rodolfo Bizarria Jr., Nicole Marie Gerardo, Andre Rodrigues

“…In light of this, we redefine Escovopsis as a monophyletic clade whose main feature is to form terminal vesicles on conidiophores. Consequently, E. kreiselii and E. trichodermoides were recombined into two new genera, Sympodiorosea and Luteomyces, as S. kreiselii and L. trichodermoides, respectively. …”
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A Review on the Effect of Crumb Rubber Addition to the Rheology of Crumb Rubber Modified Bitumen by Mohd Rasdan Ibrahim, Herda Yati Katman, Mohamed Rehan Karim, Suhana Koting, Nuha S. Mashaan

“…Finally several techniques of chemical modification to terminal blends of CRMB and the subsequent improvement to the settling property of CRMB are explained.…”
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