A case of severe Aicardi–Goutières syndrome with a homozygous RNASEH2B intronic variant by Yuri Shibata, Akimichi Shibata, Takeshi Mizuguchi, Naomichi Matsumoto, Hitoshi Osaka

“…The severity of the patient’s symptoms underscores the critical role of the C-terminal region of RNase H2B.…”
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Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma by Zihao Deng, Lixia Liu, Guantai Xie, Zhenming Zheng, Jieyou Li, Wenchong Tan, Yaotang Deng, Jinxin Zhang, Manfeng Liang, Yingxia Wu, Zhifeng Zhou, Yan Li, Yukui Chen, Yaling Huang, Hairou Su, Guibing Wu, Xiongjie Shi, Shengpei Cen, Yandan Liao, Yilin Liu, Fei Zou, Xuemei Chen

“…This study aims to discover the mechanism of Hsp90 inhibition on lipid accumulation and investigate the different effects of Hsp90 N-terminal domain inhibitor STA9090 and C-terminal domain inhibitor novobiocin on FASN protein stability and transcription pathway in HCC. …”
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The Opportunity of Using Diode Laser with the Length of 1940 nm in the Treatment of Hemorrhoids by S. A. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, O. A. Mainovskaya, Yu. L. Trubacheva, O. Yu. Fomenko, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. M. Battalova, E. M. Bogdanova

“…Transrectal ultrasound with Dopplerography was performed, which made it possible to diagnose a 2–3-fold decrease in blood flow along the terminal branches of the upper rectal artery, and internal hemorrhoids determined earlier, before surgery, were not visualized already 1 month after surgery. …”
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Pre-immunotherapy alters stereotactic ablative radiotherapy-induced systemic T cell responses in early-stage NSCLC by Chao Liu, Yanjuan Chen, Xiaohui Li, Zhijie Bai, Meilin Jiang, Dongsheng Sheng, Wenxue Zou, Rui Huang, Qingyu Huang, Fuhao Wang, Jingyang Zhu, Huiru Sun, Bing Liu, Zongcheng Li, Bing Sun

“…Of note, both SABR and icSABR largely changed TCR clonotypes, which were mainly large clones post-SABR but single clone post-icSABR, and predominantly from terminal effector CD8+ T cells and T helper cells, respectively. …”
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Finite Time Control for Fractional Order Nonlinear Hydroturbine Governing System via Frequency Distributed Model by Bin Wang, Lin Yin, Shaojie Wang, Shirui Miao, Tantan Du, Chao Zuo

“…Firstly, the mathematical model of HGS with external random disturbances is introduced. Secondly, a novel terminal sliding surface is proposed and its stability to origin is proved based on the frequency distributed model and Lyapunov stability theory. …”
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Preparation and Spectral Properties of Mixed-Ligand Complexes of VO(IV), Ni(II), Zn(II), Pd(II), Cd(II) and Pb(II) with Dimethylglyoxime and N-acetylglycine by Shayma A. Shaker

“…The IR and (1H, 13C) NMR spectra which have indicate that the dimethylglyoxime was coordinated with the metal ions through the N and O atoms of the oxime group and N-acetylglycine was coordinated with metal ions through the N atom and terminal carboxyl oxygen atom.…”
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The Disparagement of Pain: Social Influences on Medical Thinking by Harold Merskey, Robert W Teasell

“…This view diminished somewhat once anesthesia became available, although it still holds true for some forms of pain, eg, pain associated with terminal cancer. Pain was then treated as less troublesome when it became a reason for disability compensation to be paid. …”
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Linguistic Misogyny as a Parodic Device: Valspeak Markers in Jimmy Fallon’s “Ew!” by Pierre Habasque

“…Such features include lexical items, higher fundamental frequency, a prosodic contour (High Rising Terminal), a voice quality (creaky voice), and a shift in vowel quality. …”
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Abelia x grandiflora 'Edward Goucher' by Edward F. Gilman

“…Reaching a height of 6 to 10 feet with a spread of 6 feet, the gently rounded form of glossy abelia is clothed from spring through fall with terminal clusters of delicate pink and white, small, tubular flowers. …”
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Vehicle Routing and Scheduling of Flex-Route Transit under a Dynamic Operating Environment by Yue Zheng, Liangpeng Gao, Wenquan Li

“…First, we discuss the new operating polices after the introduction of intelligent transportation systems (ITSs), including automatic vehicle location (AVL) system, mobile data terminal (MDT), and computer-aided dispatch (CAD) system. …”
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Berth Allocation and Quay Crane Assignment Considering the Uncertain Maintenance Requirements by Siwei Li, Liying Song

“…The strategic optimization of a container terminal’s quayside assets, including the berth and quay cranes, is crucial for maximizing their deployment and utilization. …”
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Reniscymnus gen. nov., a new genus of Scymnini (Coleoptera, Coccinellidae) from the Oriental region by Feng Peng, Mingjie Tang, Xingmin Wang, Xiaosheng Chen

“…This newly identified genus can be distinguished from the remaining members of the tribe Scymnini by its short antenna consisting of eight antennomeres and an inflated antennal club bearing two extremely long setae; the narrow frons; the slightly tapering apically terminal maxillary palpomere; as well as the recurved and laterally almost complete abdominal postcoxal lines that enclose a distinctly wide area. …”
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Sustained Activity of Metabotropic Glutamate Receptor: Homer, Arrestin, and Beyond by Geehoon Chung, Sang Jeong Kim

“…In turn, these effector molecules bind to or phosphorylate the mGlu C-terminal binding domains and consequently regulate the activation state of the mGlu.…”
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Grouping Formation and Obstacle Avoidance Control of UAV Swarm Based on Synchronous DMPC by Yunfeng He, Xianjun Shi, Jianhua Lu, Chaolun Zhao, Guorong Zhao

“…By combining the velocity obstacle method with synchronous DMPC and providing corresponding terminal components, a leader layer control law is designed. …”
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Research and Implementation of Intelligent Home Pension System Based on Speech and Semantic Recognition by Guokun Xie, Sen Hao, Peipei Zhang, Ningning Wang

“…In this method, data transmission, instruction uploading, and receiving are completed by designing the communication interface of home appliance terminal to build the wireless intelligent home communication subsystem, and the voice module of IfI is adopted. …”
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Vortex-Induced Vibration Suppression of Bridges by Inerter-Based Dynamic Vibration Absorbers by Junjie Chen, Michael Z. Q. Chen, Yinlong Hu

“…The vortex-induced vibration may cause fatigue of a bridge structure, affecting the safety of vehicles and the comfort of pedestrians. Inerter is a two-terminal device, which has been applied in many areas. …”
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Adaptive Fixed-Time 6-DOF Coordinated Control of Multiple Spacecraft Formation Flying with Input Quantization by Shiyu Wang, Ruixia Liu, Lihua Wen

“…Firstly, a new multispacecraft nonsingular fixed-time terminal sliding mode vector is derived by using neighborhood state information. …”
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Emerging Stem Cell Therapies: Treatment, Safety, and Biology by Joel Sng, Thomas Lufkin

“…The discovery of adult stem cells has led to an ongoing revolution of therapeutic and regenerative medicine and the proposal of novel therapies for previously terminal conditions. Hematopoietic stem cell transplantation was the first example of a successful stem cell therapy and is widely utilized for treating various diseases including adult T-cell leukemia-lymphoma and multiple myeloma. …”
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Solvent-Free Ring Cleavage Hydrazinolysis of Certain Biginelli Pyrimidines by Mohamed A. Said, Wagdy M. Eldehna, Hazem A. Ghabbour, Maha M. Kabil, Nasser S. Al-shakliah, Hatem A. Abdel-Aziz

“…The nonisolable carbohydrazide intermediates are formed firstly followed by the intermolecular nucleophilic attack of terminal amino group of hydrazide function on sp2 C6 rather than the sp3 C4 to give the ring adduct which was produced as a final product.…”
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A Hybrid OFDM-TDM Architecture with Decentralized Dynamic Bandwidth Allocation for PONs by Taner Cevik

“…Instead of sending bandwidth demands to the optical line terminal (OLT) which is the only competent authority, each optical network unit (ONU) runs the same bandwidth demand determination algorithm. …”
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