Characteristics and Source-specific Health Risks of Ambient PM2.5-bound PAHs in an Urban City of Northern Taiwan by Yu-Chieh Ting, Chun-Hung Ku, Yu-Xuan Zou, Kai-Hsien Chi, Jhy-Charm Soo, Chin-Yu Hsu, Yu-Cheng Chen

“…Traffic emissions were the strongest contributor to human health risk, thus pointing to the significance of control over vehicle exhaust. …”
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Targeting murine metastatic cancers with cholera toxin A1-adjuvanted peptide vaccines by Sanchari Paul, Mustafa Kaya, Olivia Johnsson, Hanna Grauers Wiktorin, Andreas Törnell, Mohammad Arabpour, Kristoffer Hellstrand, Anna Martner

“…When comparing antigens admixed with CTA1-DD to those fused with a CTA1-based adjuvant, the fusion construct elicited the strongest immunogenicity. Nevertheless, by administrating a 20-fold higher antigen dose also the admix formulation provided efficient protection against metastasis.…”
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Non3 is an essential Drosophila gene required for proper nucleolus assembly by E. N. Andreyeva, A. A. Ogienko, A. A. Yushkova, J. V. Popova, G. A. Pavlova, E. N. Kozhevnikova, A. V. Ivankin, M. Gatti, A. V. Pindyurin

“…Complementation and phenotypic analyses showed that these Non3 mutations can be arranged in an allelic series that includes both viable and lethal alleles. The strongest lethal allele (Non3∆600) is a genetically null allele that carries a large deletion of the gene and exhibits early lethality when homozygous. …”
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Predicting the impact of missense mutations on an unresolved protein’s stability, structure, and function: A case study of Alzheimer’s disease-associated TREM2 R47H variant by Joshua Pillai, Kijung Sung, Chengbiao Wu

“…We first demonstrated that the predicted structure retained a high accuracy in critical regions of the extracellular domain and subsequently validated the in-silico mutagenesis methods by evaluating the effects of the strongest risk variant R47H of TREM2. After validation of the R47H variant, we predicted the molecular basis and effects on protein stability and ligand-binding affinity of the R62H and D87N variants that remain unknown in current literature. …”
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Single-vehicle injury crashes on rural roads in Iceland: contribution of unforgiving roadsides to fatal and serious injuries of vehicle occupants by Audur Thora Arnadottir, Gudmundur F. Ulfarsson, Sungyop Kim

“…Driver intoxication had the strongest effect, a problem which interestingly was limited to drivers living in Iceland. …”
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Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwellin... by Fiona Boland, Emma Wallace, Frank Moriarty, Tom Fahey, Caroline McCarthy, Ann Sinéad Doherty, Mark Feighery

“…The number of drugs, deprivation and anxiety/depression symptoms were significantly associated with sub-optimal monitoring, with the strongest association seen for anxiety/depression symptoms (incidence rate ratio: 1.33, 95% CI 1.05 to 1.68). …”
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Profiles of Killer Systems and Volatile Organic Compounds of Rowanberry and Rosehip-Inhabiting Yeasts Substantiate Implications for Biocontrol by Iglė Vepštaitė-Monstavičė, Juliana Lukša-Žebelovič, Violeta Apšegaitė, Raimondas Mozūraitis, Robertas Lisicinas, Ramunė Stanevičienė, Laima Blažytė-Čereškienė, Saulius Serva, Elena Servienė

“…Among 163 isolated strains, 20% demonstrated killing activity, with <i>Saccharomyces cerevisiae</i> exhibiting the strongest killing efficiency, as well as <i>Pichia anomala</i> and <i>M. pulcherrima</i> showing broad-spectrum antagonistic activity. …”
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Assessment of WRF Land Surface Model Performance over West Africa by Ifeanyi C. Achugbu, Jimy Dudhia, Ayorinde A. Olufayo, Ifeoluwa A. Balogun, Elijah A. Adefisan, Imoleayo E. Gbode

“…The strength of the Tropical Easterly Jet (TEJ) is strongest in Noah-MP GW and Noah-MP compared with that in CLM4 and Noah. …”
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Comprehensive Assessment of the Risk of Symptomatic Embolism in Patients With Infective Endocarditis by Sebastian D. Santos‐Patarroyo, Juan A. Quintero‐Martinez, Brian D. Lahr, Supavit Chesdachai, Daniel C. DeSimone, Hector R. Villarraga, Hector I. Michelena, Larry M. Baddour

“…In multivariable analysis, a highly mobile vegetation was the strongest predictor of embolism (P<0.001). Vegetation length with interaction of IE type was also associated with embolic risk (P<0.001), with a stronger effect in native valve IE (P interaction=0.001). …”
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Amebicidal and Antiadhesion Activities of Knema retusa Extract Against Acanthamoeba triangularis T4 Genotype on Contact Lenses and Modeling Simulation of Its Main Compound, E2N, Ag... by Watcharapong Mitsuwan, Imran Sama-ae, Suthinee Sangkanu, Dhrubo Ahmed Khan, Partha Biswas, Md. Nazmul Hasan, Julalak Chuprom, Tajudeen O. Jimoh, Christophe Wiart, Masyitah Binti Zulkipli, Nor Hayati Abdullah, Maria de Lourdes Pereira, Sonia M. Rodrigues Oliveira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Tooba Mahboob, Veeranoot Nissapatorn

“…From 44 tested extracts, a chloroform extract of Kre bark showed the strongest anti-Acanthamoeba activities against both trophozoites and cysts, with MIC values of 32.25 and 62.50 μg/mL, respectively. …”
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Association of triglyceride-glucose related indices with mortality among individuals with MASLD combined with prediabetes or diabetes by Yiheng Zhang, Juanli Wu, Tao Li, Yundong Qu, Yan Wang

“…Conclusions Elevated levels of TyG, TyG-BMI, TyG-WHtR, TyG-WWI, and TyG-WC indices were associated with a poorer prognosis in MASLD patients with prediabetes or diabetes, with TyG-WWI being the strongest predictor.…”
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Assessment of Peacock Spot Disease (<i>Fusicladium oleagineum</i>) in Olive Orchards Through Agronomic Approaches and UAV-Based Multispectral Imaging by Hajar Hamzaoui, Ilyass Maafa, Hasnae Choukri, Ahmed El Bakkali, Salma El Iraqui El Houssaini, Rachid Razouk, Aziz Aziz, Said Louahlia, Khaoula Habbadi

“…Indices incorporating Red Edge and near-infrared bands, such as Red Edge and SR705-750, exhibited the strongest correlations with disease severity (correlation coefficients of 0.72 and 0.68, respectively). …”
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Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database by Aleksandar Radunović, Carol Coupland, Julia Hippisley-Cox, Christopher J McDermott, Tom A Ranger, Judith Burchardt, Xue W Mei

“…Among those from the Red Flag tool, dysarthria had the strongest association with subsequent MND (adjusted OR (aOR): 43.2 (95% CI 36.0 to 52.0)) followed by muscle fasciculations (aOR: 40.2 (95% CI 25.6 to 63.1)) and muscle wasting (aOR: 31.0 (95% CI 19.5 to 49.4)). …”
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Disease control and quality of life in chronic spontaneous urticaria and recurrent angioedema are strongly linked, but not in all patients by Sophia Neisinger, Pascale Salameh, Annika Gutsche, Felix Aulenbacher, Frank Siebenhaar, Marcus Maurer

“…Different domains of the QoL PROMs showed different degrees of influence on disease control, with “Itching/Embarrassment” showing the strongest correlation with the UCT (CR −0.804; p < 0.001) and “Functioning” with the AECT3mo (CR −0.824; p < 0.001). …”
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Sol–gel synthesis of silicon oxide (SiO2) nanoparticles: exploring gas sensing and photocatalytic applications by Laxmi D. Sonawane, Abhinay S. Mandawade, Anil B. Gite, Sarika D. Shinde, Ganesh E. Patil, Latesh K. Nikam, Vishal H. Goswami, Ramesh B. Bhise, Pradip B. Sarawade, Mahendra S. Shinde

“…Among these materials, SiO₂ NPs displayed the strongest response to H₂S gas, showing outstanding gas-sensing performance at a concentration of 100 ppm. …”
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Characteristics That Predict Psoriatic Arthritis by the Classification Criteria for Psoriatic Arthritis in Patients With Juvenile Idiopathic Arthritis 18 Years After Disease Onset by Agnes Szentpetery, Mia Glerup, Kristiina Aalto, Ellen D. Arnstad, Anders Fasth, Troels Herlin, Charlotte Myrup, Ellen Nordal, Suvi Peltoniemi, Marite Rygg, Veronika Gjertsen Rypdal, Lillemor Berntson

“…Presence of psoriasis and dactylitis at disease onset were the strongest predictors for the development of PsA. Further studies on the utility of CASPAR criteria in patients with JIA are needed.…”
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Machine learning prediction models for mortality risk in sepsis-associated acute kidney injury: evaluating early versus late CRRT initiation by Chuanren Zhuang, Ruomeng Hu, Ke Li, Zhengshuang Liu, Songjie Bai, Sheng Zhang, Xuehuan Wen

“…SHAP analysis identified maximum lactate levels, age, and minimum SpO2 as the strongest predictors of mortality, while CRRT timing showed relatively lower impact on outcome prediction.ConclusionWhile later initiation of CRRT in S-AKI patients was associated with improved survival, this benefit comes with increased healthcare resource utilization. …”
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Deer Browsing Increases Stem Slenderness and Crown Irregularity and Modifies the Effects of Light Gradients on Architecture of Forest Tree Saplings by Cecilia Cacciatori, Anna Gazda, Jan Bodziarczyk, Kacper Foremnik, Aklilu B. Madalcho, Zbigniew Maciejewski, Remigiusz Pielech, Andrzej Tomski, Antoni Zięba, Tomasz Zwijacz‐Kozica, Jerzy Szwagrzyk

“…CI increased significantly with BI across all height classes, with the strongest effects in medium and tall saplings. Light reduced CI in browsed short saplings but had inconsistent effects on unbrowsed individuals. …”
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A Data-Driven Approach to Engineering Instruction: Exploring Learning Styles, Study Habits, and Machine Learning by Lauren Genith Isaza Dominguez, Antonio Robles-Gomez, Rafael Pastor-Vargas

“…Voting Ensemble was found to be the strongest model, explaining 83% of the variance in final exam scores, with a mean absolute error of 3.18. …”
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Compound identification of Shuangxinfang and its potential mechanisms in the treatment of myocardial infarction with depression: insights from LC-MS/MS and bioinformatic prediction by Yize Sun, Yize Sun, Haibin Zhao, Zheyi Wang

“…Neocryptotanshinone showed the strongest binding to MAPK3, suggesting it as a pivotal active ingredient. …”
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