Exploring novel and potent glycogen synthase kinase-3β inhibitors through systematic drug designing approach by Shabir Ahmad Ganai, Suma Mohan, Shahid Ahmad Padder

“…The stability of the strongest molecule (most potent) was evaluated in the active site of the above-mentioned kinase keeping its apo-form as reference. …”
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Distribution, Size, and Shape of Abdominal Aortic Calcified Deposits and Their Relationship to Mortality in Postmenopausal Women by Melanie Ganz, Marleen de Bruijne, Erik B. Dam, Paola Pettersen, Morten A. Karsdal, Claus Christiansen, Mads Nielsen

“…In a combined Cox regression model, the strongest complementary predictors were the number of calcifications (HR=2.76) and the area percentage (HR=−3.84). …”
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Bioimpedance as an alternative tool for subjective, visual scoring of a prevalent ham quality defect by Abie Sisay Mebre, Suliga Paweł, Egelandsdal Bjørg, Münch Daniel

“…When comparing with visual scoring, Pearson correlation analysis shows the strongest correlation for bioimpedance (Py, r = −0.46, R2 = 21%), followed by pHu (r = 0.44, R2 = 19%). …”
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Tracking of Blood Pressure in Children and Adolescents in Germany in the Context of Risk Factors for Hypertension by Giselle Sarganas, Angelika Schaffrath Rosario, Claudia Niessner, Alexander Woll, Hannelore K. Neuhauser

“…BP in childhood is the strongest independent predictor of future BP but its predictive value is limited.…”
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The Association of Economic Outcome and Geriatric Syndromes among Older Adults with Transcatheter Aortic Valve Replacement (TAVR) by Min Ji Kwak, Rafia Rasu, Robert O. Morgan, Jessica Lee, Nahid J. Rianon, Holly M. Holmes, Abhijeet Dhoble, Dae Hyun Kim

“…When the interactions of the geriatric syndromes were tested for association with the outcomes, delirium in the absence of dementia but presence of frailty showed the strongest association with cost (increase by 45.1%, 95% CI 26.45~66.45), and delirium in the absence of both dementia and frailty showed the strongest association with LOS (increase by 74.5%, 95% CI 62.71~87.13). …”
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Antifungal and Antibacterial Activity of Aqueous and Ethanolic Extracts of Different <i>Rosa rugosa</i> Parts by Žaneta Maželienė, Jolita Kirvaitienė, Kamilė Kaklauskienė, Rasa Volskienė, Asta Aleksandravičienė

“…<i>rugosa</i> parts analyzed, the petals exhibited the strongest antifungal activity.…”
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The Protective Role of Ambient Ultraviolet Radiation Against Dementia: An Ecological Analysis of Global Data by Wenpeng You

“…Results A significant inverse correlation between UVR and dementia incidence was identified (r = −0.764, p < 0.001), which persisted after adjusting for confounding factors. UVR emerged as the strongest predictor of dementia incidence, explaining a substantial portion of the variance, followed by aging as the second strongest predictor. …”
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Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo by Yanfei Li, Dafa Shi, Haoran Zhang, Xiang Yao, Ke Ren

“…The microscopic appearance presents the strongest renal damage in CI-AKI mice that existed between 12 h (P<0.0001) and 24 h (P<0.05) after contrast medium (CM) injection. …”
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Composition of Free and Bound Phenolics from Paeonia suffruticosa Andr. Flowers and Their Antioxidant and α-Glucosidase inhibitory Activities by CHEN Ling, WANG Xuefang, LI Zhining, ZHANG Lipan, LI Xiao, NING Erjuan

“…For both varieties, FP exhibited the strongest inhibitory activity against α-glucosidase with half maximal inhibitory concentrations of 12.15 and 13.87 μg/mL, respectively. …”
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Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures by Isaac Dadzie, Shaibu Adams Avorgbedo, Regina Appiah-Opong, Obed Cudjoe

“…Cytotoxic effect of SMM was also strongest towards MCF-7 cells whilst the least cytotoxic sample was SGM (IC50 > 1000 μg/ml). …”
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Predictors of depression among Chinese college students: a machine learning approach by Lin Luo, Junfeng Yuan, Chenghan Wu, Yanling Wang, Rui Zhu, Huilin Xu, Luqin Zhang, Zhongge Zhang

“…Results The RFA identified several factors associated with depression risk, with suicidal ideation, anxiety, and sleep quality exhibiting the strongest associations. Other significant predictors included academic stress, BMI, vital capacity, psychological resilience, physical fitness test scores, major satisfaction, and social network use. …”
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Discovery of novel biphenyl compounds bearing hydroxamic acid moiety as the first PD-L1/class I HDACs dual inhibitors by Dandan Yuan, Yali Gao, Lin Xia, Han Liu, Xingye Wu, Xueyan Ding, Yudan Huang, Changchun Deng, Jin Li, Wenqi Dai, Jieqing Liu, Junjie Ma

“…Among them, compound 14 displayed the strongest inhibitory activity in vitro against HDAC2 and HDAC3 with IC50 values of 27.98 nM and 14.47 nM, and had an IC50 value of 88.10 nM for PD-1/PD-L1 interaction. …”
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Changes of structure and functional properties of rice protein in the fresh edible rice during the seed development by Dan Li, Mingjing Yao, Yang Yang, Bing Wang, Dongjie Zhang, Na Zhang

“…Fresh rice protein at MMS has the strongest surface hydrophobicity while fresh edible rice protein at RS has the strongest oil holding capability. …”
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Predictive Factors of Concerns about Falling in People with Parkinson’s Disease: A 3-Year Longitudinal Study by Magnus Lindh-Rengifo, Stina B. Jonasson, Niklas Mattsson, Susann Ullén, Maria H. Nilsson

“…When adjusting for baseline FES-I scores, the strongest predictive factor was problems maintaining balance while dual tasking (β = 0.161), which was followed by age (0.131) and female sex (0.105). …”
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Phenolic Compounds from Ocimum basilicum Revealed as Antibacterial by Experimental and Computational Screening-Based Studies against Oral Infections by Salsabila Aqila Putri, Euis Julaeha, Natsuko Kagawa, Dikdik Kurnia

“…In addition, the strongest binding affinity of hydroxycinnamic acid derivatives is chlorogenic acid (−9.16 kcal·mol−1). …”
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Optimal distribution modeling and multifractal analysis of wind speed in the complex terrain of Sichuan Province, China by Cun Zhan, Renjuan Wei, Lu Zhao, Shijun Chen, Chunying Shen

“…Among landform types, plains exhibited the strongest multifractality, followed by plateaus, with mountains showing the weakest multifractality. …”
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Association of PPAR Alpha Intron 7 G/C, PPAR Gamma 2 Pro12Ala, and C161T Polymorphisms with Serum Fetuin-A Concentrations by Bernadett Márkus, Krisztián Vörös, Dorina Supák, Zsolt Melczer, Károly Cseh, László Kalabay

“…Postinfarction status (p=0.041) and BMI (p<0.001) but not PPARγ2 Pro were the strongest determinants of fetuin-A concentrations. …”
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Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro by Dong-Liang He, Ri-Ya Jin, Hui-Zhen Li, Qing-Ye Liu, Zhi-Jun Zhang

“…Compared with free PSO, HA/PSO/C NPs showed notably enhanced cytotoxicity and had the strongest potency to human glioma cell line U251. Conclusion. …”
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Pharmacovigilance imbalance analysis of VEGFR-TKI-related taste and smell disorders by Zhong-hua Fu, Chenglong Zhao, Yaqin Wang, Lei Zhang, Lei Wang

“…Cabozantinib showed the highest number of reports and strongest correlation with ageusia, taste disorder, parosmia, and anosmia. …”
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THE PROBLEM OF EVALUATING THE COMPETITIVENESS OF THE TRAVEL SECTOR AND TOURISM IN THE COUNTRIES OF THE EUROPEAN UNION by O. Gorbunova

“…The four most competitive EU countries based on the above index with their weakest and strongest features have been analysed. Based on the TTCI a comparative analysis between the four countries on one hand and Bulgaria on the other hand has been conducted. …”
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