STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment by Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor

“…Therapeutic responses resulting from intratumoral STING activation were characterized by improved VN, enhanced tumor infiltration by CD8+ T cells and CD11c+ DCs and local TLS neogenesis, all of which were dependent on host expression of STING. …”
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The potential of melatonin in sepsis-associated acute kidney injury: Mitochondrial protection and cGAS-STING signaling pathway by Yuchun Cao, Xiaofang He, Zeyuan Liu, Liying Miao, Bin Zhu

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Multidimensional System Identification and Active Vibration Control of a Piezoelectric-Based Sting System Used in Wind Tunnel by Yi Yu, Xing Shen, Yun Huang

“…In wind tunnel tests, the cantilever sting is usually used to support aircraft models because of its simple structure and low aerodynamic interference. …”
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Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway by YiLin Chen, ChengCheng Yang, YuShan Miao, DongChen Shi, Xiang Li, Sen Tian, YiFei Zhang, ChengFei Xu, YuChao Dong, ChaoFeng Han, Hui Shi, Chong Bai

“…Abstract Acute and chronic inflammation are important pathologies of benign airway stenosis (BAS) fibrosis, which is a frequent complication of critically ill patients. cGAS-STING signalling has an important role in inflammation and fibrosis, yet the function of STING in BAS remains unclear. …”
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A Turbo‐Charging System‐Like Contrast Agent for MRI‐Guided STING Pathway‐Activated Cancer Immunotherapy by Bin Ren, Sihua Yan, Zongheng Li, Ya Huang, Haobin Cai, Jing Yang, Qingdeng Fan, Chunmei Chen, Fanchao Que, Guochao Wu, Lin Huang, Ruilong Zhou, Jiaoyang Zhu, Chenggong Yan, Gang Liu, Zheyu Shen, Shipeng Ning

Subjects: “…stimulator of interferon genes (STING)…”
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Enhancing bioactive compound stability of stinging nettle (Urtica dioica L.) leaves via advanced packaging techniques by Mia Dujmović, Mia Kurek, Zdenko Mlinar, Sanja Radman, Nevena Opačić, Sandra Voća, Jana Šic Žlabur

“…Stinging nettle (Urtica dioica L.) is a highly nutritious plant, as it contains a variety of phytochemicals that contribute to the health-promoting properties of the human organism. …”
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Inhalable nanovesicles loaded with a STING agonist enhance CAR-T cell activity against solid tumors in the lung by Tianchuan Zhu, Yuchen Xiao, Zhenxing Chen, Hanxi Ding, Shoudeng Chen, Guanmin Jiang, Xi Huang

“…This targeted delivery effectively avoids the systemic inflammation and poor cellular uptake that plague free STING agonists. Internalized STING agonists trigger STING signaling and induce interferon responses, which diminish immunosuppressive cell populations such as myeloid-derived suppressor cells in the tumor microenvironment and promote CAR-T cell infiltration. …”
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Editorial: Activation of the cGAS-STING pathway by extra-nuclear DNA and its pharmacognostic modulation in human disease by Preston M. McCourt, Charles A. Day, Souren Paul, Souren Paul

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IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING by Xue Zeng, Xiaosong Li, Yundong Zhang, Chaoxia Cao, Qin Zhou

“…Besides, the activation of cGAS-STING signaling enhanced the expression of type I IFN and its downstream molecule PD-L1 through the TBK1-IRF3 pathway. …”
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AIM2 promotes excitatory glutamate receptor expression by inhibiting STING and contributes to bone cancer pain in male mice by Linhan Wang, Xueqin Xu, Shanchun Su, Biyun Li, Kunyu Zhang, Xiuqin Yu, Yangqiao Xiao, Shuangshuang Lu, Zihao Lu, Yanqiong Wu, Changbin Ke

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Ethnobotany of stinging nettle (Urtica simensis Hochst. ex. A. Rich.) in the Oromia region of central and southeastern highlands of Ethiopia by Tigist Tadesse Shonte, Kebede Woldetsadik

“…Abstract Background Stinging nettle, Urtica simensis, has a wide range of distribution in the highlands of Ethiopia with untapped potential for a sustainable supply of healthy and nutritious food. …”
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KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis by Yonghu Chen, Xilin Wu, Zhe Jiang, Xuezheng Li

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Inhibitory effect of stinging nettle (Urtica dioica L.) extract on body weight gain in rats on a high-fat diet by Kenan Kaçak, Turan Yaman, Ahmet Uyar, Ahmet Ufuk Kömüroğlu

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A High-Quality Phased Genome Assembly of Stinging Nettle (<i>Urtica dioica</i> ssp. <i>dioica</i>) by Kaede Hirabayashi, Christopher R. Dumigan, Matúš Kučka, Diana M. Percy, Gea Guerriero, Quentin Cronk, Michael K. Deyholos, Marco Todesco

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Hyperbaric oxygen facilitates teniposide-induced cGAS-STING activation to enhance the antitumor efficacy of PD-1 antibody in HCC by Jian Lv, Kui-Sheng Yang, Chuan-Qi Xu

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Lentinan-functionalized PBAE-G-nanodiamonds as an adjuvant to induce cGAS-STING pathway-mediated macrophage activation and immune enhancement by Zhiqiang Zhang, Li Wang, Xia Ma, Hui Wang

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Gluten-Free Corn Cookies Incorporated With Stinging Nettle Leaf Flour: Effect on Physical Properties, Storage Stability, and Health Benefits by Mary Nkongho Tanyitiku, Prisca Bessem, Igor Casimir Njombissie Petcheu

“…The incorporation of stinging nettle leaf flour increased (p<0.05) the ash and protein content of corn cookies from 0.32% (control) to 2.56% (20% stinging nettle leaf flour incorporation) and 6.44% (control) to 21.52% (20% stinging nettle leaf flour incorporation), respectively. …”
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A guide to selecting high-performing antibodies for STING1 (Uniprot ID: Q86WV6) for use in western blot, immunoprecipitation, and immunofluorescence [version 2; peer review: 2 approved] by Vera Ruíz Moleón, Carl Laflamme, Kathleen Southern, Riham Ayoubi, Charles Alende, Maryam Fotouhi

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Identification of Cytosolic DNA Sensor cGAS-STING as Immune-Related Risk Factor in Renal Carcinoma following Pan-Cancer Analysis by Zheng Wu, Ying Lin, Li-Min Liu, Yan-Li Hou, Wei-Ting Qin, Lei Zhang, Shu-Heng Jiang, Qin Yang, Yong-Rui Bai

“…A gene signature related to the cGAS-STING score was identified. The pan-cancer landscape of cGAS-STING expression was calculated using the RNAseq data acquired from the TCGA cohort. …”
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OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response by Yang Yang, Yuanyuan Zeng, Jianjie Zhu, Jianjun Li, Lei Gu, Lin Wei, Zeyi Liu, Jian‐an Huang

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