MicroRNA155 in non-small cell lung cancer: a potential therapeutic target by Xiangju Wei, Xiangju Wei, Xianmin Xiong, Xianmin Xiong, Ze Chen, Bi Chen, Cantang Zhang, Wenhui Zhang

“…Lung cancer (LC) is the second most commonly diagnosed cancer among both men and women, and it stands as the leading cause of cancer-related mortality, characterized by high rates of morbidity and mortality. …”
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Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity by Jiaqi Ma, Cory M. Ayres, Chad A. Brambley, Smita S. Chandran, Tatiana J. Rosales, W. W. J. Gihan Perera, Bassant Eldaly, William T. Murray, Steven A. Corcelli, Evgenii L. Kovrigin, Christopher A. Klebanoff, Brian M. Baker

“…Our findings thus reveal a novel mechanism driving TCR specificity for a cancer neoantigen that is rooted in the dynamic and allosteric nature of peptide/MHC-I binding grooves, with implications for resolving long-standing and often confounding questions about T cell specificity.…”
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A Young Male with Severe Myocarditis and Skeletal Muscle Myositis by Abdalla Ibrahim, Eoghan Meagher, Alexander Fraser, Thomas J. Kiernan

“…His myocarditis symptoms resolved with steroids and anti-inflammatory treatment, but on closer questioning, he reported a vague history of long-standing calf discomfort associated with episodes of stiffness, fatigue, and flu-like symptoms. …”
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Innovations in intestinal organoid technology featuring an open apical surface by Ye Chen, Yi Wang

“…The 3D intestinal organoid system has resolved many long-standing challenges associated with immortalized or cancer cell cultures, offering unparalleled capabilities for modeling gastrointestinal development and diseases. …”
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Examining Psychological Elements in the Works of Khaled Hosseini by Shaghayegh Tamizifar, Mohammad Ebrahim Irajpour, Zahra Aghababaii

“…The masterful intertwining of psychological themes with cultural authenticity solidifies his standing as a distinguished literary figure. This study aims to dissect various aspects of Hosseini's work with a focus on analyzing psychological elements. …”
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Chromosome-level genome assembly of Fistularia commersonii (Syngnathiformes, Fistulariidae) by Zufa Ding, Cheng Wang, Yuting Qian, Wenjun Chen, Dan Yu, Yang Liu, Liandong Yang, Ying Wang

“…Notably, the contig N50 value stands at 15.67 Mb, while the scaffold N50 value reaches an impressive 18.69 Mb. …”
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Development of a Portable Gait Rehabilitation System for Home-Visit Rehabilitation by Hiroaki Yano, Naoki Tanaka, Kiyotaka Kamibayashi, Hideyuki Saitou, Hiroo Iwata

“…The LI has two 2 degree-of-freedom (DOF) manipulators with footpads to move each foot along a trajectory. When the user stands on the footpads, the system can move his or her feet while the body remains stationary. …”
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A CPW-Fed Circular Wide-Slot UWB Antenna with Wide Tunable and Flexible Reconfigurable Dual Notch Bands by Yingsong Li, Wenxing Li, Qiubo Ye

“…The numerical and experimental results show that the proposed antenna has a wide bandwidth ranging from 2.7 GHz to 12 GHz with voltage standing wave ratio (VSWR) less than 2, except for the two notch bands operating at 3.8–5.9 GHz and 7.7–9.2 GHz, respectively. …”
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On Travelling Wave Modes of Axially Moving String and Beam by Lei Lu, Xiao-Dong Yang, Wei Zhang, Siu-Kai Lai

“…The traditional vibrational standing-wave modes of beams and strings show static overall contour with finite number of fixed nodes. …”
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Prediction of OCT contours of short-term response to anti-VEGF treatment for diabetic macular edema using generative adversarial networks by Xueying Yang, Fabao Xu, Han Yu, Zhongwen Li, Xuechen Yu, Zhiwen Li, Li Zhang, Jie Liu, Shaopeng Wang, Shaopeng Liu, Jiaming Hong, Jianqiao Li

“…Diabetic macular edema (DME) stands as a leading cause for vision loss among the working-age population. …”
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The Effects of Artificial vs. Natural Rearing on Growth Performance, Thyroid Hormone Levels, Locomotor Activity, Carcass Traits and Meat Quality Characteristics in Chios Lambs by Panagiotis Simitzis, Georgia Alexopoulou, Eftychis Karampekos, Konstantina Linardopoulou, Anargyros Rigakis, Niki Stamelou, Michael Goliomytis, Iosif Bizelis, Ioannis Bossis

“…The lambs’ behavior was continuously videotaped until weaning, and their standing percentage was recorded as an activity index. …”
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Effect of Electroacupuncture Prestimulation with Mental Tri-Needles on the Inflammatory Response of Hippocampus in Aged Rats with Perioperative Neurocognitive Disorders by WANG Xiangfeng, HUANG Jinyan, LIU Wei, LUO Huiqin, WANG Guanhui, LIN Qin, CHEN Bin

“…Open field experiment and water maze test were used to evaluate the cognitive function; ELISA method was used to detect interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α in the plasma; HE staining was used to observe the cell morphology of hippocampal tissue; TUNEL staining was used to observe the apoptosis of hippocampal tissue; Western blot and real-time fluorescence quantitative PCR were used to detect the protein content and mRNA expression of IL-1β, IL-6 and TNF-α in hippocampal tissue.Results(1) Cognitive function: compared with the control group and the anesthesia group, the time of staying in the central quadrant, the number of crossings of the quadrant, the number of standing ups, the total distance of swimming, the swimming speed and the number of platform crossings in the operation group significantly decreased, and the latency and the time of staying in the target quadrant were significantly prolonged (<italic>P</italic>&lt;0.05); compared with the operation group, the time of staying in the central square, the number of crossings of the quadrant, the number of standing ups, the total distance of swimming, the swimming speed and the number of platform crossings in the acupuncture group significantly increased, and the latency and the time of staying in the target quadrant were significantly shortened (<italic>P</italic>&lt;0.05). (2) Levels of IL-1β, IL-6 and TNF-α in plasma: compared with the control group, the levels of IL-1β, IL-6 and TNF-α significantly increased in the anesthesia group, operation group and acupuncture group (<italic>P</italic>&lt;0.05); compared with the anesthesia group, the levels of IL-1β, IL-6 and TNF-α in the operation group significantly increased (<italic>P</italic>&lt;0.05); compared with the operation group, the levels of IL-1β, IL-6 and TNF-α in the acupuncture group significantly decreased (<italic>P</italic>&lt;0.05). (3) Morphology and apoptosis of hippocampal neurons: the most sever injury of hippocampal neurons occured in the operation group, showing as interstitial edema and a small amount of glial cell proliferation, while the injury of hippocampal neurons was slight and the morphology was relatively normal in the acupuncture group. …”
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TOPICAL ISSUES OF EDUCATIONAL LAW IN THE CONDITIONS OF DIGITAL TRANSFORMATION OF THE EDUCATION by Elena S. Balashova, Lyudmila V. Gnetova, Ekaterina S. Surovegina

“…The article is devoted to the study of factors standing in the way of improving educational law as a branch. …”
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Orta Asya’da Enerji Politikaları ve Küresel Rekabet Bağlamında Türkiye’nin Rolü Üzerine Bir Değerlendirme by Bahar ÖZSOY, Esra Banu SİPAHİ, Yusuf SAYIN

“…Recently, the energy issue that has been risen to the top of Turkey’s agenda with Turkish natural gas and oil exploration endeavors on the Black Sea and the Mediterranean Sea and with the war between Russia and Ukraine, stands out as the main factor to redefine regional and global relations. …”
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From the History of Corporate Mercenarism: British Clandestine Operation in the North Yemen in 1960s by M. A. Nebolsina

“…However, the British operation in Yemen stands out in that regard as it was for the first time since the end of the World War II that such mission was carried out by mercenaries alone. …”
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The possibility of obtaining beta-anhydrite from waste nitrogypsum by Marinković S., Kostić-Pulek A., Popov S., Đinović J., Trifunović Prvoslav

“…When the β- anhydrite was mixed with water at a W/S (water/solid) ratio of 0.54 in presence of different accelerators (CaO, mixture CaO - ash, ash, Na2SO4 and K2SO4), pastes were formed which hardened on standing. The compressive strength of the hardened samples was measured after 7 and 28 days and their composition determined by qualitative IR analysis. …”
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« I Speak According to the Book » : écriture et logos dans Nixon in China de John Adams et Alice Goodman by Mathieu Duplay

“…While this question was repeatedly raised in North America throughout the twentieth century, its most detailed formulation occurs in the works of Marshall McLuhan; thus, his study of writing as a medium will be invoked in an attempt to highlight the opera’s original contribution to this long-standing debate. Close analysis both confirms that such a parallel is justified up to a point and reveals its limitations. …”
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Brown Bear, Brown Bear, What Can You See? Exploring the Tension Between Strategic Choices and Claimants’ Voices in Environmental Litigation in the EU by Reilly Anne Dempsey Willis

“…Challenges in legal standing and establishing individual harm or direct concern have an enormous impact on what claims are heard and how they are heard.…”
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Students from all Layers of Society. Study Grants, Parents and the Education of their Children, 1815-2015 by Wouter Marchand

“…Study grants for adolescents from lower class or low-income families can promote upward intergenerational social mobility, since they remove the financial barriers of continuing education and can lead to occupations of a higher standing. By investigating the social background and careers of a sample of grant students compared to the overall student populations, this paper uncovers to what extent study grants had an effect on an individual and societal scale. …”
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Ab initio study of C14 laves phases in Fe-based systems by Pavlu J., Šob M.

“…Fe2Fe, Fe2X, X2Fe, X2X, where X stands for Si, Cr, Mo, W, Ta) were investigated using the pseudopotential VASP (Vienna Ab initio Simulation Package) code employing the PAW-PBE (Projector Augmented Wave - Perdew Burke-Ernzerhof) pseudopotentials. …”
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