PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism? by Justine Henriot, André Dallmann, François Dupuis, Jérémy Perrier, Sebastian Frechen

“…The resulting CYP3A4 expression profile and two previously published profiles were applied to PBPK models of seven CYP3A4 substrates (alfentanil, alprazolam, felodipine, midazolam, sildenafil, triazolam, and verapamil) built‐in PK‐Sim®. For each compound, it was assessed whether first‐pass metabolism could be adequately predicted based on the integrated CYP3A4 expression profile alone or whether an optimization of Pmucosa was required. …”
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Neutrinoless double beta decay from scalar leptoquarks: interplay with neutrino mass and flavor physics by P. S. Bhupal Dev, Srubabati Goswami, Chayan Majumdar, Debashis Pachhar

“…Abstract We perform a comprehensive analysis of neutrinoless double beta (0νββ) decay and its interplay with low-energy flavor observables in a radiative neutrino mass model with scalar leptoquarks S 1( 3 ¯ $$ \overline{3} $$ , 1, 1/3) and R ~ 2 3 2 1 / 6 $$ {\overset{\sim }{R}}_2\left(3,2,1/6\right) $$ . We carve out the parameter region consistent with constraints from neutrino mass and mixing, collider searches, as well as measurements of several flavor observables, such as muon and electron anomalous magnetic moments, charged lepton flavor violation and rare (semi)leptonic kaon and B-meson decays, including the recent anomalies in R D ∗ $$ {R}_{D^{\left(\ast \right)}} $$ and B → Kν ν ¯ $$ B\to K\nu \overline{\nu} $$ observables. …”
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Racial disparities in extended venous thromboembolism prophylaxis after hysterectomy. by Wenbo Wu, Sherry Wu, Sim Berlene Mariano, Richard E Burney, Jonathan P Kuriakose

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Safety attitudes, burnout and well-being among healthcare workers during the COVID-19 pandemic: an Indo-Pacific regional cross-sectional study by Abhiram Kanneganti, Benjamin Yong Qiang Tan, Nik Hisamuddin Nik Ab Rahman, Aloysius Sheng-Ting Leow, Max Denning, Ee Teng Goh, Lucas Jun Hao Lim, Ching-Hui Sia, Ying Xian Chua, James Kinross, Melanie Tan, Li Feng Tan, Yi Min Wan, Arvind Sharma, Rivan Danuaji, RN Komal Kumar, Chew Keng Sheng, Cheah Phee Kheng, Sarah Shaikh Abdul Karim, Mohd Najib Abdul Ghani, Suhaimi Mahmud, Yiong Huak Chan, Vijay Kumar Sharma, Kang Sim, Shirley Beng Suat Ooi

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Error Correction of Meteorological Data Obtained with Mini-AWSs Based on Machine Learning by Ji-Hun Ha, Yong-Hyuk Kim, Hyo-Hyuc Im, Na-Young Kim, Sangjin Sim, Yourim Yoon

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PRISM-Med: Parameter-Efficient Robust Interdomain Specialty Model for Medical Language Tasks by Jieui Kang, Hyungon Ryu, Jaehyeong Sim

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A scoping review of digital workplace wellness interventions in low- and middle-income countries. by Yi Chiann Thai, Deanna Sim, Tracy A McCaffrey, Amutha Ramadas, Hema Malini, Jessica L Watterson

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Low-density SNP marker sets for genetic variation analysis and variety identification in cultivated citrus by Phuong Linh Nguyen, Jin-Kee Jung, Jee-Soo Park, Sung-Chur Sim

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A risk prediction score to identify patients at low risk for COVID-19 infection by Wui Mei Chew, Chee Hong Loh, Aditi Jalali, Grace Shi En Fong, Loshini Senthil Kumar, Rachel Hui Zhen Sim, Russell Pinxue Tan, Sunil Ravinder Gill, Trilene Ruiting Liang, Jansen Meng Kwang Koh, Tunn Ren Tay

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Computational fracture and thermal analysis of glass-ceramics using ReaxFF reactive molecular dynamics simulations by Domenica Rodriguez, Hyung Sub Sim, Eungyo Choi, Sung-Yup Kim, Jinsu Nam, Seungho Kim, Sungwook Leo Hong

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Understanding the Reinforcing Mechanisms in Kenaf Fiber/PLA and Kenaf Fiber/PP Composites: A Comparative Study by Seong Ok Han, Mehdi Karevan, I. Na Sim, Md A. Bhuiyan, Young Hun Jang, Jonathan Ghaffar, Kyriaki Kalaitzidou

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Praxe tradicional do desenvolvimento comunitário e a emergência do apoio para continuidade dos projectos comunitários em Moçambique by Artur Horacio Macuácua

“…Este trabalho traz elementos constitutivos da emergência de uma nova abordagem do intervencionismo comunitário que incita as organizações da sociedade civil, levar às comunidades, não só, mais um programa/projecto mas sim, acções que se constituem como solução consistente e continua que responda aos anseios das comunidades numa perspectiva de actuação inovadora e desafiadora no âmbito da funcionalidade das organizações da sociedade civil moçambicanas. …”
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Augmented Reality for extremity hemorrhage training: a usability study by Krishant Tharun, Alberto Drogo, Carmine Tommaso Recchiuto, Serena Ricci, Serena Ricci

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Automated Subfield Volumetric Analysis of Hippocampus in Patients with Drug-Naïve Nondementia Parkinson’s Disease by Jin-Woo Park, Chan-Nyoung Lee, Youngbo Sim, Hyung-Kyu Ham, Woo-Suk Tae, Byung-Jo Kim

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Enhanced Antitumor Immune Response in 2′-5′ Oligoadenylate Synthetase-Like 1- (OASL1-) Deficient Mice upon Cisplatin Chemotherapy and Radiotherapy by Chan Kyu Sim, Jung Hoon Lee, In-Jeoung Baek, Sang-Wook Lee, Myeong Sup Lee

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Water Quality Assessment of Tributaries of Batang Baleh in Sarawak Using Cluster Analysis by Teck-Yee Ling, Chen-Lin Soo, Teresa-Lee-Eng Heng, Lee Nyanti, Siong-Fong Sim, Jongkar Grinang, Karen-Suan-Ping Lee, Tonny Ganyai

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Probiotic Potential and Enhanced Adhesion of Fermented Foods-Isolated Lactic Acid Bacteria to Intestinal Epithelial Caco-2 and HT-29 Cells by Eun Ah Sim, Seon-Young Kim, SangNam Kim, Eun-Gyung Mun

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Dropping the baton: Cognitive biases in emergency physicians. by Mingwei Ng, Evelyn Wong, Guek Gwee Sim, Pek Jen Heng, Gareth Terry, Foo Yang Yann

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Lessons from COVID-19 and Seoul: Effects of Reduced Human Activity from Social Distancing on Urban CO2 Concentration and Air Quality by Hayoung Park, Sujong Jeong, Ja-Ho Koo, Sojung Sim, Yeon Bae, Yeonsoo Kim, Chaerin Park, Jeongyeon Bang

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Psicanálise e pesquisa social de hermenêutica profunda by Thomas Leithauser

“…Adorno, entretanto, acrescenta com razão que, em contraposição à opinião pedagógica dominante da psicanálise, não se trata apenas de um fenômeno individual, e sim, ao mesmo tempo, um fenômeno social geral. Essa concepção crítica do inconsciente foi retomada particularmente em termos metodológicos pelo psicanalista frankfurtiano Alfred Lorenzer. …”
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