Proximally based sural artery flap for the reconstruction of soft tissue defects around the knee and proximal third of the leg in India: a clinical study by Lakshmi Palukuri, Sreedharala Srinivas, Dharmapuri Madhulika, Sanujit Pawde, Ajo Sebastian, Swathi Sankar, Sandeep Reddy Chintha

“…The most common cause of injury was trauma resulting from road traffic accidents. The majority of defects were found in the proximal third of the leg, particularly on the anterolateral aspect. …”
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Nano-curcumin Effects on Ischemic Stroke clinical outcomes and Interleukin-6 Levels: Pilot Randomized Clinical Trial by Zeinab Ehtiatkar, Alia Saberi, Samaneh Ghorbani Shirkouhi, Mozaffar Hosseininezhad, Shahrokh Yousefzadeh-Chabok, Yaser Moadabi, Ashkan Karimi, Haniyeh Shadrou Gharani, Sasan Andalib

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Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France by Huamao Mark Lin, Keith L. Davis, James A. Kaye, Katarina Luptakova, Saurabh P. Nagar, Mohamad Mohty

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Role of Long Non-Coding RNA GUSBP11 in Chronic Periodontitis Through Regulation of miR-185-5p: A Retrospective Cohort Study by Zhang X, Shen X

“…Xiaowen Zhang, Xiang Shen Department of Stomatology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, 226001, People’s Republic of ChinaCorrespondence: Xiang Shen, Department of Stomatology, Affiliated Hospital of Nantong University, No. 20, Xisi Road, Chongchuan District, Nantong, Jiangsu, 226001, People’s Republic of China, Tel +86-0513-81161901, Email Shenxiangdr@163.comPurpose: Previous studies have shown that long non-coding RNA GUSBP11 is abnormally expressed in patients with periodontitis, but the specific mechanism remains to be investigated. …”
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H₂S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins by Rahib K. Islam, Erinn Donnelly, Erminia Donnarumma, Fokhrul Hossain, Jason D. Gardner, Kazi N. Islam

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Prevention and Reversal of Diabetes by All-Trans Retinoid Acid and Exendin-4 in NOD Mice by Jyuhn-Huarng Juang, Yang-Hau Van, Chien-Hung Kuo, Mei-Yin Lin, Ying-Hsiu Liu, Han-Ying Chang

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A Novel Method for Preparation of Carrageenan/Fish Scale Collagen/Allopurinol Biocomposite Film by Quoc Manh Vu, Thuy Chinh Nguyen, Duong My Ngoc Dam, Quoc Trung Vu, Trong Lu Le, Tran Dung Hoang, Thi Kim Ngan Tran, Tuan Anh Nguyen, Phi Hung Nguyen, Hoang Thai

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Management Modalities of Mandible Fracture and Dental Trauma in Pediatric Patients During Mixed Dentition Phase: A Series of Case Study by Lomtu Ronrang, Alice Lyngdoh

“…But sometimes, we come across children who have suffered traumatic head and neck injuries, including mandible fractures, usually falling from a height, and road site accidents while playing on the roadsides, including traffic accidents, which are inevitable. …”
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Effects of Food on the Pharmacokinetics and Safety of HA121-28 Tablet, a Novel Multi-Targeting Tyrosine Kinase Inhibitor, in Healthy Chinese Subjects: A Phase I Clinical Trial by Liu Y, Li X, Zhang M, Men Y, Wang Y, Zhu X, Zheng L

“…Yixian Liu,1,2,* Xiaoyu Li,1,2,* Mengyu Zhang,1,2 Yuchun Men,1,2 Ying Wang,1,2 Xiaohong Zhu,1,2 Li Zheng1,2 1Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2Clinical Trial Center, NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Zheng, Cancer Center, West China Hospital, Sichuan University, No. 5 Telecom Road, Wuhou District, Chengdu, 610041, People’s Republic of China, Email zhengli@wchscu.cnPurpose: HA121-28, a novel multi-targeting tyrosine kinase inhibitor, has dual efficacy against tumor growth and neovascularization. …”
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Research and development of Cordyceps in Taiwan by Ching-Peng Chiu, Tsong-Long Hwang, You Chan, Mohamed El-Shazly, Tung-Ying Wu, I-Wen Lo, Yu-Ming Hsu, Kuei-Hung Lai, Ming-Feng Hou, Shyng-Shiou Yuan, Fang-Rong Chang, Yang-Chang Wu

“…Finally, we summarized the bottle-necks and challenges facing Cordyceps research as well as we proposed future road map for Cordyceps industry in Taiwan.…”
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Distinct ecological processes shape micro-eukaryotic generalists and specialists in a canal-disturbed wetland, Lake Weishan, China by Xinghao Li, Yunfeng Wang, Micah Dunthorn, Chengzhi Mao, Qiaoyi Kong, Saleh A. Al-Farraj, Weibo Song, Jie Huang

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Virtual online consultations: advantages and limitations (VOCAL) study by Trisha Greenhalgh, Joe Wherton, Sara Shaw, Charles Gutteridge, Emma Byrne, Isabel Hodkinson, Shanti Vijayaraghavan, Desirée Campbell-Richards, Satya Bhattacharya, Philippa Hanson, Seendy Ramoutar, Anna Collard, Joanne Morris

“…Data will be analysed and synthesised using a sociotechnical framework developed from structuration theory.Ethics approval City Road and Hampstead NHS Research Ethics Committee, 9 December 2014, reference 14/LO/1883.Planned outputs We plan outputs for 5 main audiences: (1) academics: research publications and conference presentations; (2) service providers: standard operating procedures, provisional operational guidance and key safety issues; (3) professional bodies and defence societies: summary of relevant findings to inform guidance to members; (4) policymakers: summary of key findings; (5) patients and carers: ‘what to expect in your virtual consultation’.Discussion The research literature on video consultations is sparse. …”
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Engineered Perfluorochemical Cancer-Derived Exosomes Loaded with Indocyanine Green and Camptothecin Provide Targeted Photochemotherapy for Effective Cancer Treatment by Lee YH, Huang CY

“…Yu-Hsiang Lee,1– 3 Cheng-You Huang1 1Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 2Department of Chemical and Materials Engineering, National Central University, Taoyuan City, Taiwan, Republic of China; 3Department of Medical Research, Cathay General Hospital, Taipei City, Taiwan, Republic of ChinaCorrespondence: Yu-Hsiang Lee, Department of Biomedical Sciences and Engineering, National Central University, No. 300, Jhongda Road, Taoyuan City, 320317, Taiwan, Republic of China, Tel +886-3-422-7151 Ext# 27755, Fax +886-3-280-4627, Email yuhsianl@ncu.edu.twBackground: Cancer treatments are still limited by various challenges, such as off-target drug delivery, posttreatment inflammation, and the hypoxic conditions in the tumor microenvironment; thus, the development of effective therapeutics remains highly desirable. …”
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Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model by Qiong Liang, Qiqing Lin, Yueyong Li, Weigui Luo, Xia Huang, Yujie Jiang, Chunyan Qin, Jin Nong, Xiang Chen, Suren Rao Sooranna, Liao Pinhu

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Digital leadership in quantity surveying: unveiling key characteristics and their role in driving digital transformation by Darren Vermaak, Gerrit Crafford

“…It highlights adaptability, a visionary approach, innovation, and a sense of urgency as key traits for effective digital leadership. It provides a road map for quantity surveying firms to navigate the digital era successfully. …”
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GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…Yue Wang,1– 5 Jiang Fang,1– 5 Qiang Yuan,1– 5 Jian Yu,1– 5 Jin Hu1– 5 1Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 2National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 3Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 4Neurosurgical Institute of Fudan University, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of China; 5Shanghai Clinical Medical Center of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, People’s Republic of ChinaCorrespondence: Jian Yu; Jin Hu, Department of Neurosurgery, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai, 200040, People’s Republic of China, Tel +86 21 52889999, Email hujin@fudan.edu.cn; lance2000@hotmail.comBackground: Traumatic brain injury (TBI) is a prevalent neurological disorder associated with significant public health burdens and long-term risks, including neurodegenerative diseases such as Parkinson’s disease (PD). …”
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Integrating artificial Intelligence-Based metaheuristic optimization with Machine learning to enhance Nanomaterial-Containing latent heat thermal energy storage systems by Ali Basem, Hanaa Kadhim Abdulaali, As’ad Alizadeh, Pradeep Kumar Singh, Komal Parashar, Ali E. Anqi, Husam Rajab, Pancham Cajla, H. Maleki

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Significantly Elevated Serum Lipase in Pregnancy with Nausea and Vomiting: Acute Pancreatitis or Hyperemesis Gravidarum? by Amanda Johnson, Bethany Cluskey, Nina Hooshvar, Daphne Tice, Courtney Devin, Elaine Kao, Suhalia Nawabi, Steven Jones, Lihua Zhang, Chi Dola

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Comparative monocyte and T cell responses in DENV-exposed subjects from South-East Asia and DENV-naïve residents in Taiwan by Sheng-Hsuan Wang, Yun-Erh Chuang, Sia-Seng Tan, Tzu-Chuan Ho, Oscar Guey Chuen Perng, Po-Lin Chen

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Cortical Reorganization following Injury Early in Life by Moran Artzi, Shelly Irene Shiran, Maya Weinstein, Vicki Myers, Ricardo Tarrasch, Mitchell Schertz, Aviva Fattal-Valevski, Elka Miller, Andrew M. Gordon, Dido Green, Dafna Ben Bashat

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