Real-World Implementation of Particle-Based Microfluidics: On-Spot Test for Iron and Copper Ions in Water by Indrek Saar, Hanno Evard

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Correction: Exploring the impact of trait number and type on functional diversity metrics in real-world ecosystems

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Outcomes of Pembrolizumab plus chemotherapy for patients with metastatic non-squamous NSCLC: Real-world evidence by Irina Surovtsova, Felix J. F. Herth, Daria B. Kokh, Philipp Morakis

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Cognitive strategies for UAV trajectory optimization: Ensuring safety and energy efficiency in real-world scenarios by Mushtaq Muhammad Umer, Hein Venter, Owais Muhammad, Tamoor Shafique, Fuad A. Awwad, Emad A.A. Ismail

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Predicting dupilumab effectiveness with Type-2 biomarkers: A real-world study of severe asthma by Kenji Mizumura, Yasuhiro Gon, Norihiro Harada, Shiho Yamada, Asami Fukuda, Ryosuke Ozoe, Shuichiro Maruoka, Sumiko Abe, Kazuhisa Takahashi, Akihiko Tanaka, Hironori Sagara, Taisuke Akamatsu, Toshihiro Shirai, Katsunori Masaki, Koichi Fukunaga, Konomi Kobayashi, Hiroyuki Nagase, Nobuaki Miyahara, Arihiko Kanehiro, Noboru Kitamura, Naruhiko Sugihara, Fumio Kumasawa, Junko Terada-Hirashima, Masayuki Hojo, Kazuyuki Chibana, Etsuko Tagaya

“…Background: The therapeutic effectiveness of dupilumab for severe asthma in real-world settings is yet to be prospectively investigated across multiple institutions, and uncertainties persist regarding predictive factors for its effectiveness. …”
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Prevalence of Lp(a) in a real-world Portuguese cohort: implications for cardiovascular risk assessment by Miguel Saraiva, Jonatas Garcez, Beatriz Tavares da Silva, Inês Poças Ferreira, José Carlos Oliveira, Isabel Palma

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Effectiveness of antipsychotic medication in patients with schizophrenia in a real world retrospective observational study in Ethiopia by Mulualem Kelebie, Getasew Kibralew, Gebresilassie Tadesse, Gidey Rtbey, Mekidem aderaw, Wondale Endeshaw, Mitiku Belachew, Mulu Muche, Diemesew Getnet, Setegn Fentahun

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Switching to Dolutegravir/lamivudine or Bictegravir/Emtricitabine/Tenofovir alafenamide. A comparative real-world study by Hernando Knobel, Esperanza Cañas-Ruano, Ana Guelar, Pablo Knobel, Judit Villar-García, Alicia González-Mena, Ceclia Canepa, Itziar Arrieta-Aldea, Augustin Marcos, Agustí Abalat-Torrres, Roberto Güerri-Fernández

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Longitudinal Relationship between the Introduction of Medicinal Cannabis and Polypharmacy: An Australian Real-World Evidence Study by Maja Kalaba, Graham M. L. Eglit, Matthew T. Feldner, Patrizia D. Washer, Tracie Ernenwein, Alistair W. Vickery, Mark A. Ware

“…Recent studies recommend medicinal cannabis (MC) as a potential treatment for chronic pain (CP) when conventional therapies are not successful; however, data from Australia is limited. This real-world evidence study explored how the introduction of MC related to concomitant medication use over time. …”
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Leveraging Real-World Evidence to Define Severe RSV Lower Respiratory Tract Disease in Adults by Catherine A. Panozzo, Edward E. Walsh, Zhen Yang, Eleanor Wilson, Jaya Goswami, Sonia K. Stoszek, Adrianna Loback, Tony Ng, Beverly M. Francis, Alana K. Simorellis, Wenmei Huang, Linwei Li, Rebecca Vislay-Wade, Zhe Zheng, Evan J. Anderson, Allison August, Grace Chen, Ann R. Falsey

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A real-world Pharmacovigilance study of brodalumab based on the FDA adverse event reporting system by Ke He, Kaidi Zhao, Tingyi Yin, Meng Liu, Jiashu Liu, Wenqian Du, Xinyi Liu, Baochen Cheng, Dewu Zhang, Yan Zheng

“…Although it has demonstrated favorable efficacy and safety in clinical trials, the strict inclusion and exclusion criteria may not fully reflect its safety profile in real-world settings. As its use becomes more widespread in clinical practice, understanding its safety in real-world applications is crucial. …”
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Real-World Experience of Clascoterone Cream 1% in Acne Management: Case Series and Canadian Experience by Tay E, Loo WJ

“…Moreover, clascoterone also helped to address other concerns in several patients, including hirsutism, hidradenitis suppurativa, retinoid-induced dermatitis, androgenetic alopecia, folliculitis, postinflammatory hyperpigmentation, and laser-induced acne flares. This early real-world clinical experience supports the effectiveness, tolerability, and versatility of clascoterone cream 1% for patients with acne across a variety of clinical and demographic characteristics.Keywords: androgen, topical, therapy, efficacy, safety, tolerability…”
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Canadian real-world study of access and clinical results using dupilumab for chronic rhinosinusitis with polyps by Shaun J. Kilty, Andrea Lasso

“…The goal of the study was to assess its effectiveness and efficacy in a real-world setting. This study aims to assess how clinical outcomes of biologic therapy in real-world application (effectiveness) correspond to outcomes in clinical trials (efficacy) and to look into factors that might explain an efficacy-effectiveness gap. …”
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Correction: Exploring the impact of trait number and type on functional diversity metrics in real-world ecosystems. by Timothy Ohlert, Kaitlin Kimmel, Meghan Avolio, Cynthia Chang, Elisabeth Forrestel, Benjamin Gerstner, Sarah E Hobbie, Kimberly Komatsu, Peter Reich, Kenneth Whitney

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Real world data on digital remote refraction in a healthy population of 14,680 eyes by Casper van der Zee, Heshow Jamal, Marc Muijzer, Laurence Frank, Gerko Vink, Robert Wisse

“…Abstract Refractive errors are the leading cause of preventable visual impairment, to which web-based remote refraction could contribute. We report real-world 2021–2022 data of the underlying algorithm and validated these to conventional prescriptions among healthy individuals (high visual acuity and satisfactied current refraction). …”
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Translating lab success to the field: Evaluating coffee biochar-enhanced concrete in real-world construction by Rajeev Roychand, Shannon Kilmartin-Lynch, Mohammad Saberian, Jie Li, Chun Qing Li

“…Building upon our pioneering laboratory research on coffee biochar in concrete, this study presents a world-first field trial, translating lab-based findings into real-world construction applications. Our previous experimental work demonstrated that biochar derived from pyrolysing spent coffee grounds (SCGs) at 350°C, when used as a partial replacement of fine aggregates, could enhance concrete strength by up to ∼30 %. …”
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Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study by Barrachina Jordi, Margarit César, Andreu Blanca, Zandonai Thomas, Ballester Pura, Muriel Javier, Cutillas Esperanza, Peiró Ana M.

“…Our aim was to explore the impact of therapeutic alliance on analgesic outcomes in a real-world interdisciplinary pain unit (PU). A cross-sectional observational study was conducted on outpatients (n = 69) using opioids on a long-term basis for the treatment of chronic non-cancer pain, where clinical pharmacologists and pharmacists advised patients about their opioid treatment. …”
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Apnet: Lightweight network for apricot tree disease and pest detection in real-world complex backgrounds by Minglang Li, Zhiyong Tao, Wentao Yan, Sen Lin, Kaihao Feng, Zeyi Zhang, Yurong Jing

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Real-world treatment patterns of patients with acute coronary syndrome based on 15-year data by Inga S. Egorova, Natalia N. Vezikova

“…AIM: To evaluate the real-world clinical features, treatment approaches, and outcomes in patients with ACS based on data from the long-term registry of the Regional Vascular Center. …”
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Population pharmacokinetics of ramipril in patients with chronic heart failure: A real-world longitudinal study by Trobec Katja Čvan, Grabnar Iztok, Trontelj Jurij, Lainščak Mitja, Kos Mojca Kerec

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