Foot orientation and trajectory variability in locomotion: Effects of real-world terrain. by Emma Gibson, Greg Douglas, Katelyn Jeffries, Julianne Delaurier, Taylor Chestnut, Jesse M Charlton

“…This may be an important factor to consider when making comparisons of real-world walking bouts, as greater proportions of one terrain feature in a data set could create bias in the outcomes. …”
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Real world pharmacovigilance assessment of drug related macular degeneration risks by Xiaodong Chen, Shinan Wu, Shaopan Wang, Chaofeng Yu, Zihan Guo, Shiya Huang, Peixin Cai, Yanliang Miao, Shiying Li, Qian Chen

“…To enhance clinical practice and reduce the risk of drug-related macular degeneration, we analyzed drug-related trends using real-world data. Disproportionality analysis of adverse event reports from the FDA Adverse Event Reporting System (FAERS, 2004–2023) identified 67,683 cases involving 1402 drugs. …”
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Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products by Maihöfner C, Mallick-Searle T, Vollert J, Kalita P, Sood Sethi V

“…Ltd, SingaporeCorrespondence: Vidhu Sood Sethi, GSK Consumer Healthcare Singapore Pte Ltd (Co Regn No. 201309040M), 23 Rochester Park #03-02, 139234, Singapore, Tel +6596447203, Email vidhu.x.sethi@haleon.comAbstract: In recent years, regulatory authorities have signaled a willingness to consider real-world evidence (RWE) data to support applications for new claims and indications for pharmaceuticals. …”
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Real-world experience with TTFields in glioma patients with emphasis on therapy usage by Claudius Jelgersma, Joan Alsolivany, Gülsüm Akkas, David Wasilewski, David Wasilewski, Bastian Gastl, Martin Misch, David Capper, David Capper, David Kaul, David Kaul, Lars Bullinger, Lars Bullinger, Peter Vajkoczy, Julia Onken, Julia Onken, Julia Onken

“…Given the cost-intensive nature and mild- to- moderate constraints associated with the therapy, our objective is to generate real-world data on therapy usage through a retrospective analysis at a high-throughput academic center. …”
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Real-world clinical and psychosocial outcomes among people with mild or moderate haemophilia A treated on-demand in the Italian CHESS II cohort: a real-world data analysis by Castaman Giancarlo, Mancuso Maria Elisa, Di Minno Matteo Nicola Dario, Sannino Luigi, Tempre Rosaria, Bendinelli Sara, Blenkiron Tom, Burke Tom, Grazzi Enrico Ferri

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Differences in Energy Consumption in Electric Vehicles: An Exploratory Real-World Study in Beijing by Kezhen Hu, Jianping Wu, Tim Schwanen

“…This paper explores how the energy efficiency of EVs is affected and shaped by driving behavior, personal driving styles, traffic conditions, and infrastructure design in the real world. Tests have been conducted with a Nissan LEAF under a typical driving cycle on the Beijing road network in order to improve understanding of variations in energy efficiency among drivers under different urban traffic conditions. …”
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Real-world tafamidis experience in hereditary transthyretin amyloidosis with peripheral neuropathy in Brazil by Luiz Felipe Pinto, Marcus V. Pinto, Paula Accioli, Gabriela Amorim, Renata Gervais de Santa Rosa, Moises Dias, Mariana Guedes, Carlos P. Gomez, Roberto C. Pedrosa, Marcia Waddington-Cruz

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Real-world evaluation of an evidence-based telemental health program for PTSD symptoms by Jocelynn T. Owusu, Lu Wang, Shih-Yin Chen, Robert E. Wickham, Scott T. Michael, Nazneen F. Bahrassa, Alethea Varra, Jennifer L. Lee, Connie Chen, Anita Lungu

“…However, its effectiveness in diverse, real-world settings is not well-understood. This evaluation aimed to assess clinical outcomes of a BCT program for PTSD symptoms. …”
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Demographic clinical trial diversity assessment methods: Use of real-world data by Hua Chen, Nnadozie Emechebe, Sudeep Karve, Leon Raskin, Jailene Leal, Ning Cheng, Wendy Sebby, Kim Ribeiro, Samuel Crawford

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Efficacy and safety of telitacicept in IgA nephropathy: a real-world study by Lingqiu Dong, Dandan Yang, Aiya Qin, Siqing Wang, Yi Tang, Jiaxing Tan, Wei Qin

“…Telitacicept is a humanized fusion protein composed of a transmembrane activator and calcium-modulating cyclophilin ligand interactor receptor and human IgG.Aim To evaluate the efficacy and safety of telitacicept in adult patients with IgAN in a real-world study.Methods Biopsy-proven IgAN patients with 24-hour proteinuria greater than 0.5 g/d who received 240 mg telitacicept weekly were recruited for this study and 1:1:1 matched with patients who received supportive treatment only or immunosuppressive treatment by propensity score matching. …”
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MEMS Acoustic Sensors: Charting the Path from Research to Real-World Applications by Qingyi Wang, Yang Zhang, Sizhe Cheng, Xianyang Wang, Shengjun Wu, Xufeng Liu

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Acknowledging and addressing real-world challenges to treating immune-related adverse events by Bonnie L Bermas, Mitchell S von Itzstein, David E Gerber, Alexa Meara

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Context-dependent memory in the real world: the role of frequency and context dwell time by Yura Choi, Kawon Kim, Sunwoo Moon, Geunseong Jung, Jae-Hyuk Cha, Hyungwook Yim

“…Results demonstrated the existence of the context-dependent memory effect in a real-world setting, with low-frequency locations showing a stronger context-dependent memory effect—benefiting more from the matched context. …”
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Real-World Long-Term Experience on Endoxifen in Bipolar Disorder with Psychotic Symptoms by Vikas Thanvi

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Real‐world efficacy of transfusion with liberal or restrictive strategy in traumatic brain injury by Liang‐Wen Cui, Nian Liu, Chao Yu, Ming Fang, Rui Huang, Cheng Zhang, Min Shao

“…Interpretation Compared with the restrictive strategy, the liberal strategy does not improve the short‐term neurological prognosis and death among patients with TBI in a real‐world situation. The liberal strategy may be beneficial to survival at very early stage or in hemodynamically unstable subgroup.…”
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Early Real-World Patient and Staff Experience With an Intracanalicular Dexamethasone Insert [Corrigendum] by Nijm L, Matossian C, Rhee MK, Stephens JD, Rosselson ME, Majmudar PA, Gollamudi SR, Patel RH, Bauskar A, Montieth A, Vantipalli S, Gibson A, Metzinger JL, Goldstein MH, Gurses Ozden R

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Advancing the development of real-world data for healthcare research in China: challenges and opportunities by Jun Zhang, Eric Wu, Jia Zhong, Honghao Fang, Larry Liu, Jipan Xie

“…Various real-world data (RWD) sources have emerged in China with the intention of generating real-world evidence (RWE) that can be used in clinical and regulatory decision-making. …”
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Adverse events in the nervous system associated with blinatumomab: a real-world study by Wen Gao, Jingwei Yu, Yifei Sun, Zheng Song, Xia Liu, Xue Han, Lanfan Li, Lihua Qiu, Shiyong Zhou, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

“…Abstract Background Nervous system toxicity (NST) is a frequent and serious adverse event (AE) associated with blinatumomab, the first bispecific antibody drug targeting CD19 and CD3. Real-world data are needed to better understand the incidence and characteristics of NST in clinical practice. …”
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Real-world Data of Antithrombotic Therapy in Neuroendovascular Therapy: Analysis of JR-NET 4 by Nozomi SASAKI, Yukiko ENOMOTO, Hiroshi YAMAGAMI, Koji IIHARA, Akira ISHII, Hirotoshi IMAMURA, Nobuyuki SAKAI, Chiaki SAKAI, Tetsu SATOW, Yuji MATSUMARU, Shinichi YOSHIMURA

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Real-world pharmacovigilance of ofatumumab in multiple sclerosis: a comprehensive FAERS data analysis by Hui Chen

“…BackgroundOfatumumab, a fully human monoclonal antibody targeting CD20, is approved for the treatment of relapsing multiple sclerosis. Comprehensive real-world safety data are crucial for informing clinical practice.MethodsThe FDA Adverse Event Reporting System database was utilized to perform a disproportionality analysis, covering reports from Q3 2020 to Q2 2024, in which ofatumumab was identified as the primary suspected drug. …”
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