Managerial thinking in neonatal care: a qualitative study of place of care decision-making for preterm babies born at 27–31 weeks gestation in England by Neena Modi, Elizabeth S Draper, Miaoqing Yang, Sarah E Seaton, Kelvin Dawson, Vasiliki Bountziouka, Oliver Rivero-Arias, Thillagavathie Pillay, Natalie Armstrong, Alexis Paton, Elaine Boyle, Victor L Banda, Caroline Cupit, Bradley Manktelow, Abdul Qader T Ismail

“…Two were neonatal intensive care units and four were local neonatal units.Participants Clinical staff (n=15) working in neonatal units, and people present in neonatal units during periods of observation.Results In the context of real-world neonatal practice, with multiple (and rapidly-evolving) uncertainties relating to mothers, babies and unit/network capacity, ‘best place of care’ protocols were only one element of much more complex decision-making processes. …”
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Safety and Effectiveness of BPaL-Based Regimens to Treat Multidrug-Resistant TB: First Experience of an Italian Tuberculosis Referral Hospital by Gina Gualano, Maria Musso, Paola Mencarini, Silvia Mosti, Carlotta Cerva, Pietro Vittozzi, Antonio Mazzarelli, Angela Cannas, Assunta Navarra, Stefania Ianniello, Paolo Faccendini, Fabrizio Palmieri

“…<b>Methods</b>: Here, we report the real-world experience of a tertiary referral hospital for TB in Italy, from 2022 to 2024, in the management, outcomes, and adverse drug reactions of a cohort of twenty-two MDR/RR patients treated with BPaL and BPaLM regimens. …”
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Etiology of Hospital-Acquired Pneumonia (HAP) and Ventilator-Associated Pneumonia (VAP) in Tertiary-Care Hospitals in Thailand: A Multicenter, Retrospective Cohort Study by Rongrungruang Y, Plongla R, Pleumkanitkul S, Hantrakun V, Khawcharoenporn T

“…., Bangkok, Thailand; 4Real World Solutions APAC, IQVIA Inc., Bangkok, Thailand; 5Infectious Diseases Unit, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, ThailandCorrespondence: Thana Khawcharoenporn, Infectious Diseases Unit, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand, 12120, Email kthana@tu.ac.thPurpose: To describe the top three causative organisms of hospital acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in Thailand.Patients and Methods: This multi-center retrospective cohort study included HAP/VAP patients hospitalized in 2019 in three university-affiliated hospitals and a private hospital in Bangkok, Thailand. …”
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Assessment of the Distributed Ledger Technology for Energy Sector Industrial and Operational Applications Using the MITRE ATT&#x0026;CK&#x00AE; ICS Matrix by Annabelle Lee, Sri Nikhil Gupta Gourisetti, David Jonathan Sebastian-Cardenas, Kent Lambert, Vicente Navarro, Marco Pasetti, Umit Cali, Kateryna Isirova, Ramesh Reddi, Puica Nitu, Md. Touhiduzzaman, Michael Mylrea, Philip Huff, Farrokh Rahimi, Shammya Shananda Saha

“…The MITRE ATT&#x0026;CK&#x00AE; matrices have been developed to document an adversary&#x2019;s tactics and techniques based on real-world observations. The MITRE ATT&#x0026;CK&#x00AE; matrices provide a common taxonomy for offense and defense and have become a valuable conceptual tool across multiple cybersecurity disciplines for conveying threat intelligence, performing testing through red teaming or adversary emulation, and enhancing network and system defenses against intrusions. …”
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Persistent effect of salt reduction in schoolchildren and their families: 1-year follow-up after an application-based cluster randomized controlled trial by Yuan Li, Puhong Zhang, Feng J. He, Rong Luo, Jing Song, Changqiong Wang, Fengge Chen, Wei Zhao, Yuhong Zhao, Hang Chen, Tianyong Wu, Xiaoyan Wang, Hui Zhou, Zhi Han, Jie Zhang

“…Continuous efforts are needed to maintain the salt reduction effects in real-world settings. Trial registration ChiCTR1800017553. …”
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Efficacy and Acceptability of a Mobile App for Monitoring the Clinical Status of Patients With Chronic Obstructive Pulmonary Disease Receiving Home Oxygen Therapy: Randomized Contr... by Anisbed Naranjo-Rojas, Luis Ángel Perula-de Torres, Freiser Eccehomo Cruz-Mosquera, Guillermo Molina-Recio

“…ObjectiveThe purpose of this study was to evaluate the efficacy and acceptability of a mobile app designed for the clinical monitoring of patients with COPD and home oxygen (HO) therapy, compared with conventional monitoring in real-world community settings. MethodsA parallel-group, nonblinded, multicenter randomized controlled trial was conducted with 45 participants; the intervention group (IG), which used the mobile app in addition to conventional monitoring (n=23) and the control group, which received only conventional monitoring (n=22), administered by therapists over a duration of 3 months. …”
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A new method for detecting mixed Mycobacterium tuberculosis infection and reconstructing constituent strains provides insights into transmission by Benjamin Sobkowiak, Patrick Cudahy, Melanie H. Chitwood, Taane G. Clark, Caroline Colijn, Louis Grandjean, Katharine S. Walter, Valeriu Crudu, Ted Cohen

“…Lastly, mixed infections in a real-world Mycobacterium tuberculosis population from Moldova were detected with MixInfect2 and clusters of recent transmission that included major and minor constituent strains were built. …”
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Fabrication and characterization of rGO-SnO2 nanocomposite for electrochemical sensor of ciprofloxacin by Prastika Krisma Jiwanti, Dewi Kartika Azizah Sukardi, Anis Puspita Sari, Mai Tomisaki, Siti Wafiroh, Sri Hartati, Arramel, Yew Hoong Wong, Pei Meng Woi, Joon Ching Juan

“…The %RSD value was less than 5 % indicating that this modified electrodes exhibit good precision and stability. The real-world applicability of this developed methods was exemplified through its successful implementation in the analysis of river water and milk, achieving remarkable recovery rates of 101.2 % and 97.7 %, respectively. …”
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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…These data highlight the importance of a multidisciplinary approach and describe real-world trends in systemic therapies, radiotherapy and surgical treatment in this rare cancer type.…”
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Grid-Scale Battery Systems for VAR Support in Con Edison Distribution Substations via Bi-Directional Smart Inverters by Mohamed K. Kamaludeen, Yusef Esa, Kirn Zafar, Elihu Nyemah, Ahmed Ali A. Mohamed, Tamer Ibrahim, Simon Odie

“…Additionally, simulations incorporating real-world grid elements at the substation were performed, including an evaluation of the combined effects of BESS VAR support with substation capacitor banks and shunt reactors. …”
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Exploring the upper ocean characteristics of a bay using coastal and regional ocean community model by D. Jaishree, P.T. Ravichandran

“…Including a three-year spin-up phase facilitated the adjustment of the model to initial conditions and the attainment of equilibrium, ensuring its fidelity to real-world conditions. The follow-up analyses and comparisons were performed five years after the spin-up phase. …”
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The Association of Inflammatory Indexes Derived from Peripheral Blood Cell Count and Clinical Signs with Response to Treatment with Dupilumab in Pediatric Patients with Moderate-to... by Zhang L, Pi J, Wang J, Chen J, Zhang Y, Li J, Wang L, Li Y, Chen A, Luo X, Wang H

“…Lingzhao Zhang,1,2 Jiangshan Pi,1,2 Jinsong Wang,3 Jingsi Chen,1 Yunxuan Zhang,1,2 Jie Li,4 Lingling Wang,1,2 Yue Li,1,2 Anwei Chen,1 Xiaoyan Luo,1,5,&ast; Hua Wang1,2,5,&ast; 1Department of Dermatology, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Chongqing Key Laboratory of Child Infection and Immunity, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Gastroenterology, Chongqing Dongnan Hospital, Chongqing, People’s Republic of China; 4Department of Pediatrics, Chongqing Jiangjin District Maternal and Child Health Hospital, Chongqing, People’s Republic of China; 5Ministry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Hua Wang; Xiaoyan Luo, Department of Dermatology, Children’s Hospital of Chongqing Medical University, No. 136 Zhongshan Second Road, Yuzhong District, Chongqing, 400015, People’s Republic of China, Tel +8615123380348, Email huawang@hospital.cqmu.edu.cn; xyluo@hospital.cqmu.edu.cnBackground: Dupilumab is a safe and effective treatment for moderate to severe atopic dermatitis (AD), but real-world data in pediatric patients in China are limited. …”
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Einstein Ordered Weighted Aggregation Operators for Pythagorean Fuzzy Hypersoft Set With Its Application to Solve MCDM Problem by Rana Muhammad Zulqarnain, Imran Siddique, Rifaqat Ali, Jan Awrejcewicz, Hanen Karamti, Dariusz Grzelczyk, Aiyared Iampan, Muhammad Asif

“…Multi-criteria decision-making is imperative in overcoming barriers to real-world complications. However, conventional methods of multi-criteria decision-making regularly provide inconsistent results. …”
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Efficacy and Safety of Chemotherapy or EGFR‐TKIs as First‐Line Therapy in NSCLC Patients Harboring Non‐Ex 20 Ins Uncommon EGFR Mutations: A Retrospective Study in China by Chen Liao, Li Bai, Tingting He, Qingle Liang, Defeng Hu, Shipeng Lei, Yong He, Yubo Wang

“…ABSTRACT Background Uncommon EGFR mutations are a kind of heterogeneous group of mutations with various responses to EGFR‐TKIs and are often excluded from most prospective clinical trials. In this real‐world retrospective study, we retrospectively compared the efficacy and safety of chemotherapy or various generations of EGFR‐TKIs as first‐line therapy in NSCLC Chinese patients harboring non‐ex 20 ins uncommon EGFR mutations. …”
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The Effect of Intravascular Imaging-Guided Percutaneous Coronary Intervention on Coronary Artery Perforation by Yuichi Sawayama, MD, Kenta Sasaki, MD, Narumi Taninobu, MD, Akihiro Ikuta, MD, Kohei Osakada, MD, Shunsuke Kubo, MD, Takeshi Tada, MD, Yasushi Fuku, MD, Hiroyuki Tanaka, MD, Yoshihisa Nakagawa, MD, Kazushige Kadota, MD

“…Objectives: The authors evaluated whether IVI-guided PCI is associated with a lower risk of PCI-related CAP in a real-world cohort. Methods: This observational study analyzed consecutive PCI procedures from January 2006 to October 2023. …”
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Multinational comparison of new antidepressant use in older adults: a cohort study by Robyn Tamblyn, David Westfall Bates, David L Buckeridge, Will Dixon, Alan J Forster, Nadyne Girard, Jennifer Haas, Bettina Habib, Siyana Kurteva, Jack Li, Therese Sheppard

“…Chronic pain was the most common potential treatment indication. Evaluation of real-world risks of TCAs is a priority for future research, given high rates of use and the potential for increased toxicity in older adults because of potent anticholinergic effects.…”
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Evaluation of the effectiveness of GASMAN anesthesia simulation software combined with case-based learning versus traditional lecture-based learning in inhalation anesthesia educat... by Chao Chen, Chao Chen, Shengfeng Yang, Xinglong Xiong, Xinglong Xiong, Yewei Shi, Yewei Shi, Zhenyan Zhu, Zhenyan Zhu, Jing Shi, Jing Shi

“…The cases used in the IGC group were structured around realistic clinical scenarios, simulating real-world challenges in inhalation anesthesia. These scenarios were integrated with the GASMAN software to provide interactive simulations, enhancing students’ understanding of pharmacokinetics and pharmacodynamics. …”
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SVM directed machine learning classifier for human action recognition network by Dharmanna Lamani, Pramod Kumar, A Bhagyalakshmi, J. Maria Shanthi, Lakshmana Phaneendra Maguluri, Mohammad Arif, C Dhanamjayulu, Sathish Kumar. K, Baseem Khan

“…This work helps to the advancement of surveillance technology, which in turn makes video analysis in applications that take place in the real world safer and more dependable.…”
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Molecular mechanisms of cis-oxygen bridge neonicotinoids to Apis mellifera Linnaeus chemosensory protein: Surface plasmon resonance, multiple spectroscopy techniques, and molecular... by Xiangshuai Li, Shiyu Li, Yang Liu, Li Cui, Daibin Yang, Shuning Chen, Xusheng Shao, Huizhu Yuan, Xiaojing Yan

“…Employing surface plasmon resonance (SPR) in conjunction with multispectral techniques and molecular modeling, this study meticulously analyzed the binding affinity, specificity, and kinetics under conditions that simulate real-world exposure scenarios. Key parameters such as the number of binding sites (n), binding constants (Ka), dissociation constants (KD), and binding distances (r) were quantitatively assessed. …”
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Blinding assessment in randomised sham-controlled trials of acupuncture:protocol for a systematic survey by Ling Li, Xin Sun, Jiali Liu, Minghong Yao, Yong Fu, Jiahui Yang, Xiaochao Luo

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