Incidence and Mechanisms of Coronary Perforations during Rotational Atherectomy in Modern Practice by Yen-Hsiang Wang, Wei-Jhong Chen, Yu-Wei Chen, Chih-Hung Lai, Chieh-Shou Su, Wei-Chun Chang, Chi-Yen Wang, Kae-Woei Liang, Tsun-Jui Liu, Wen-Lieng Lee

“…This study was to explore incidence and mechanisms of RA-induced CP in real-world practice. Knowing why CPs occur in RA should help operators avert such mishaps. …”
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Smart Manufacturing Application in Precision Manufacturing by Amr T. Sufian, Badr M. Abdullah, Oliver J. Miller

“…This work also bridges the gap in academia and in industry by showcasing a real-world actual business benefits realized from smart manufacturing, as well as showcasing the practical implementations, limitations, and opportunities of smart manufacturing applications in the precision manufacturing industry, all of which reduce the internal barriers and challenges facing smart manufacturing and industry 4.0 adoption. …”
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The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia by Kai Shen, Chenlu Yang, Jie Huang, Xiao Shuai, Ting Niu, Hongbing Ma

“…Nevertheless, its clinical characteristics and impact on APL prognosis have yet to be elucidated.ObjectivesThe aim of this study was to describe the clinical characteristics of DS-related AKI in patients with APL and its impact on patient prognosis.MethodsThis was a retrospective study from a single center in a real-world setting. APL patients who developed AKI during ATRA- and ATO-based induction were included. …”
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Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system by Ying Zhao, Yuke Zhong, Liuqing Wu, Jiao Yan, Weitao Lu

“…Abstract It’s well known that sex is a risk factor for the occurrence of adverse events (AEs), most of which have found sex differences. Real-world data studies on the sex differences of fall-risk-increasing drugs (FRIDs) are few and far between, with most small-scale retrospective studies based on FRID classes. …”
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Experience of Kenyan researchers and policy-makers with knowledge translation during COVID-19: a qualitative interview study by Edwine Barasa, Benjamin Tsofa, Mike English, Sassy Molyneux, Dorcas Mwikali Kamuya, Fatuma Hassan Guleid, Alex Njeru, Joy Kiptim, Emelda Okiro, David Kariuki

“…They felt it was important to institutionalise KT to improve readiness to respond to public health emergencies.Conclusion This study provides a real-world example of the use of KT during a public health crisis. …”
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Treating chronic kidney disease in Danish primary care: results from the observational ATLAS study by Morten Lindhardt, Søren Tang Knudsen, Thomas Saxild, Morten Charles, Rikke Borg

“…Design An observational study of CKD prevalence, treatment patterns and comorbidities in primary care based on patient record data combined with a questionnaire on diagnosis, management and treatment of impaired kidney function in a real-world, primary care setting. Setting In all 128 primary care clinics in Denmark of 211 randomly invited and a quetionnaire completed by 125/128 participating PCPs. …”
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Optimising primary molecular profiling in non-small cell lung cancer. by R D Schouten, I Schouten, M M F Schuurbiers, V van der Noort, R A M Damhuis, E H F M van der Heijden, J A Burgers, N P Barlo, A S R van Lindert, K W Maas, J J G van den Brand, A A J Smit, J M W van Haarst, B van der Maat, E Schuuring, H Blaauwgeers, S M Willems, K Monkhorst, D van den Broek, M M van den Heuvel

“…Profiling of EGFR and ALK was performed in 69.9% of 136 patients included in the run-in phase, significantly more than real-world data estimates of 55% (p<0.001). Protocolised molecular profiling increased the rate to 77.0% (p = 0.049). …”
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Effect of delivery hospital busyness on early mortality in small preterm infants: a Finnish population-based cohort study in 2006–2016 by Mika Gissler, Sari Räisänen, Seppo Heinonen, Sture Andersson, Riitta Vilkko, Markus Leskinen

“…We analysed differences in the incidence of selected adverse outcomes between quiet and busy days compared with optimal delivery-volume days by logistic regression followed by crude (ORs) and adjusted ORs (aORs) with 99% CIs.Setting A population-based cohort study based on prospectively collected real-world data from five university hospitals and 21 non-tertiary-level delivery hospitals in Finland, 2006‒2016.Participants 4323 small preterm infants.Primary outcome measures Umbilical cord pH ≤7.05, Apgar score 0–3 points at the age of 1 min, Apgar score 0–3 points at age 5 min, birth asphyxia (International Classification of Diseases-10 code), resuscitation with intubation.Secondary outcome measures Perinatal mortality comprising stillbirths and early neonatal deaths (&lt;7 days).Results Busy days (busy vs optimal) showed no correlation with the primary birth-related outcomes. …”
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“Inclisiran: Early LDL-C target achievement in a real-life population” by Francesco Briani, Mauro Bagli, Gabriele Venturi, Francesco Bacchion, Antonio Mugnolo

“…Inclisiran, a small interfering RNA, has been observed to effectively and sustainably reduce LDL-C in large randomized controlled trials (RCTs); however, real-world data on its short-term efficacy and use are limited. …”
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Transformer-Based Person Detection in Paired RGB-T Aerial Images With VTSaR Dataset by Xiangqing Zhang, Yan Feng, Nan Wang, Guohua Lu, Shaohui Mei

“…Aerial-based person detection poses a significant challenge, yet it is crucial for real-world applications like air-ground linkage search and all-weather intelligent corescuing. …”
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Post-marketing safety surveillance for the recombinant zoster vaccine (Shingrix), vaccine adverse event reporting system, United States, October 2017–April 2024 by Yamin Shu, Wenxin Cheng, Xucheng He, Liu Huang, Wei Chen, Qilin Zhang

“…Further studies are needed to continue generating real-world safety data and further characterize RZV-AE pairs systematically.…”
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Translational Science in Vascular Aging: From Bench to Bedside—Insights from a VascAgeNet Roundtable by Elisabetta Bianchini, Lynn Roth, Pierre Boutouyrie, Smriti Badhwar, Achim Schwarz, Vincenzo Gemignani, Rosa Maria Bruno, Bernhard Hametner, Chloe Park, Giacomo Pucci, Ioana Mozos, Dimitrios Terentes-Printzios, Rachel E. Climie, Andrea Guala, Jordi Alastruey, Christopher C. Mayer

“…Pragmatic and registry-based clinical trials offer viable alternatives to traditional randomized controlled trials, facilitating real-world applicability. The regulatory landscape, particularly for software medical devices, must evolve to keep pace with technological advancements like artificial intelligence. …”
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Optimizing water-use efficiency under elevated CO₂: A meta-analysis of crop type, soil modulation, and enrichment methods by Ali Mokhtar, Hongming He, Samar Attaher, Ali Salem, Muneer Alam

“…Key findings reveal that: (1) C₃ crops, such as potato and tomato, show significantly greater increases in WUE compared to C₄ crops like maize, with effect sizes of 13.96 and 7.02 for plant-level WUE (WUEₚ), suggesting that C₃ crops may be more advantageous in water-limited environments due to reduced photorespiration under eCO₂; (2) soil type substantially modulates WUE responses, with clay soils, due to their high water-holding capacity, demonstrating the highest WUE enhancements (effect sizes of 7.87 for WUEₚ and 12.54 for yield WUE, WUEᵧ), while sandy soils, characterized by rapid drainage, showed limited improvements; and (3) greenhouse and growth chamber studies displayed the highest WUE improvements, while FACE experiments, which better replicate real-world conditions, indicated smaller WUE increases due to environmental variability, underscoring the need for a hybrid approach that merges controlled data with field insights to develop practical, water-efficient agricultural strategies. …”
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The developing speciality coffee businesses of Bangkok, Thailand and Penang, Malaysia. A story of entrepreneurial passion and creativity? by Mark Azavedo, Art Gogatz

“…Its value lies in two areas, the practical real world of business, as mentioned, and for future researchers in entrepreneurship. …”
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Adaptive Hosting Capacity Forecasting in Distribution Networks with Distributed Energy Resources by Md Tariqul Islam, M. Jahangir Hossain, Md. Ahasan Habib, Muhammad Ahsan Zamee

“…Incorporating exogenous factors such as the time of day as a sensitivity gate input, further improves responsiveness, making the model more adaptable to real-world conditions. This advanced SERNN model offers a reliable framework for distribution network operators, supporting intelligent planning and proactive DER management. …”
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Experimental analysis, simulation, and evaluation of process parameters of GFRP composites produced through resin transfer molding by Khang Wen Goh, Kiran Kumar Algot, G. Laxmaiah, P. Ramesh Babu, Veda Prakash Vodnala, Rahadian Zainul

“…These properties are critical indicators of the composite’s performance in real-world applications. The results revealed that both resin injection pressure and the number of layers significantly affect the composite’s mechanical properties. …”
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Brain Computer Interface on Track to Home by Felip Miralles, Eloisa Vargiu, Stefan Dauwalder, Marc Solà, Gernot Müller-Putz, Selina C. Wriessnegger, Andreas Pinegger, Andrea Kübler, Sebastian Halder, Ivo Käthner, Suzanne Martin, Jean Daly, Elaine Armstrong, Christoph Guger, Christoph Hintermüller, Hannah Lowish

“…This is the time such technology is ready to be deployed in the real world, that is, at the target end users’ home. …”
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Improving the Generalizability and Robustness of Large-Scale Traffic Signal Control by Tianyu Shi, Francois-Xavier Devailly, Denis Larocque, Laurent Charlin

“…Furthermore, the learning scheme of the resulting model can improve zero-shot transferability to different road network structures, including both synthetic networks and real-world networks (e.g., Luxembourg, Manhattan). We conduct extensive experiments to compare our approach to multi-agent reinforcement learning and traditional transportation approaches. …”
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Simulated practice in the development of clinical reasoning in nursing students: A systematic review protocol by Rute Pires, Maria Marques, Henrique Oliveira, Margarida Goes, Miguel Pedrosa, Manuel Lopes

“…Simulated clinical practice is a pedagogical technique that replicates real-world scenarios in a controlled environment, enabling nursing students to engage in the teaching-learning process actively. …”
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Lenvatinib versus sorafenib as second-line therapy following progression on atezolizumab–bevacizumab in patients with unresectable hepatocellular carcinoma: a multicenter retrospec... by Jaekyung Cheon, Shigeo Shimose, Hyung-Don Kim, Takashi Niizeki, Min-Hee Ryu, Tomotake Shirono, Baek-Yeol Ryoo, Hideki Iwamoto, Changhoon Yoo

“…Conclusion In this real-world study, LEN demonstrated superior PFS and comparable OS to SOR as second-line treatment for uHCC after progression on AB.…”
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