Receipt of long-acting injectable antiretroviral therapy among people with HIV in Southern US states: an assessment using electronic health records and claims data by Yiyang Liu, Rebecca J. Fisk-Hoffman, Maitri Patel, Robert L. Cook, Mattia Prosperi

“…We analyzed electronic health records (EHRs) to provide real-world evidence of demographic and clinical characteristics associated with the receipt of LAI ART among people with HIV (PWH). …”
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Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn’s Disease Initiating Biologics With 3 Years of Follow-Up by Ruizhi Zhao, Zhijie Ding, Parul Gupta, Laurence Gozalo, Robert Bruette, Victor M. Johnson, Keshia Maughn, Yihang Liu, Sumesh Kachroo

“…**Background:** There is limited real-world evidence on treatment patterns of patients with Crohn’s disease (CD) initiating biologics with an extensive follow-up period. …”
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Damoctocog Alfa Pegol, a PEGylated B-domain Deleted Recombinant Extended Half-life Factor VIII for the Treatment of Hemophilia A: A Product Review by Mark T. Reding, Shadan Lalezari, Gili Kenet, Giovanni Di Minno, Jonathan Ducore, Alexander Solms, Anita Shah, Pål André Holme, Lone H. Poulsen, Karina Meijer, Mindy Simpson, Maria Elisa Mancuso

“…The efficacy, safety and pharmacokinetics (PK) of damoctocog alfa pegol have been studied extensively in the PROTECT VIII clinical trials, and its long-term safety and effectiveness profile is continuing to build through observational and interventional real-world studies. The PK of damoctocog alfa pegol was shown to be improved as compared with that of sucrose-formulated rFVIII (rFVIII-FS, Kogenate®), and was also demonstrated to be non-inferior to and, for some variables, more favorable than rFVIII-Fc fusion protein, efmoroctocog alfa (Elocta®; NCT03364998), rurioctocog alfa pegol (BAX 855, Adynovate®/Adynovi®; NCT04015492), and antihemophilic factor (recombinant) plasma/albumin-free method (rAHF-PFM, Advate®; NCT02483208). …”
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Validity of Wearable Inertial Sensors for Gait Analysis: A Systematic Review by Giuseppe Prisco, Maria Agnese Pirozzi, Antonella Santone, Fabrizio Esposito, Mario Cesarelli, Francesco Amato, Leandro Donisi

“…<b>Background/Objectives</b>: Gait analysis, traditionally performed with lab-based optical motion capture systems, offers high accuracy but is costly and impractical for real-world use. Wearable technologies, especially inertial measurement units (IMUs), enable portable and accessible assessments outside the lab, though challenges with sensor placement, signal selection, and algorithm design can affect accuracy. …”
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A Systems-Based Analysis of the CardioMEMS HF Sensor for Chronic Heart Failure Management by Jeffrey S. Tran, Aaron M. Wolfson, Daniel O’Brien, Omid Yousefian, David M. Shavelle

“…Hemodynamic-guided therapy using the CardioMEMS™ system has been shown to reduce heart failure hospitalization (HFH) in both clinical trials and real-world settings. However, the CardioMEMS system requires input from multiple independent elements to achieve its effect, and no studies have been done to investigate those elements. …”
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Development of a social learning theory-based pressure injury training program for nursing assistants in Chinese nursing homes by Yanxia Guo, Yanxia Guo, Shengnan Yang, Plernpit Boonyamalik, Arpaporn Powwattana, Wen Zhu, Lingxia Xu

“…Future research should focus on the implementation and evaluation of this program in real-world settings to determine its effectiveness in improving nursing assistants’ skills and reducing PI incidence among older adult residents.…”
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Satellite-Based Forest Stand Detection Using Artificial Intelligence by Patrik Kovacovic, Rastislav Pirnik, Julia Kafkova, Mario Michalik, Alzbeta Kanalikova, Pavol Kuchar

“…The selected model was then evaluated using images not included in the original training dataset to simulate real-world deployment scenarios. The final accuracy of best model achieved 91.67%. …”
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Human-centered design of a health recommender system for orthopaedic shoulder treatment by Akanksha Singh, Benjamin Schooley, John Mobley, Patrick Mobley, Sydney Lindros, John M. Brooks, Sarah B. Floyd

“…Abstract Background Rich data on diverse patients and their treatments and outcomes within Electronic Health Record (EHR) systems can be used to generate real world evidence. A health recommender system (HRS) framework can be applied to a decision support system application to generate data summaries for similar patients during the clinical encounter to assist physicians and patients in making evidence-based shared treatment decisions. …”
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Advanced Microgrid Protection Utilizing Zero Sequence Components With Hard-Ware-in-the-Loop Testing by Zahra Ghanem, Feras Alasali, Naser El-Naily, Hassen Loukil, Haytham Y. Mustafa, Saad M. Saad, Abdelaziz Salah Saidi, William Holderbaum

“…The proposed strategy is extensively validated through Hardware-in-the-Loop (HIL) testing, ensuring its feasibility and effectiveness in real-world scenarios. HIL testing confirms the practical applicability and robustness of the proposed protection scheme, enhancing its reliability. …”
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Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer by Mengying Yuan, Yuankun Zheng, Fei Wang, Niuniu Bai, Niuniu Bai, Haoling Zhang, Yuan Bian, Yuan Bian, Hao Liu, Hao Liu, Xia He, Xia He

“…However, due to many factors affecting drugs in the real world, PGx still accounts for a small proportion of actual clinical application scenarios. …”
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State updating of the Xin'anjiang model: joint assimilating streamflow and multi-source soil moisture data via the asynchronous ensemble Kalman filter with enhanced error models by J. Gong, J. Gong, X. Liu, C. Yao, C. Yao, Z. Li, A. H. Weerts, A. H. Weerts, Q. Li, S. Bastola, Y. Huang, J. Xu

“…Tests involving both synthetic and real-world cases demonstrates that assimilation of these two types of observations simultaneously substantially reduces the accumulation of past errors in the initial conditions at the start of the forecast, thereby aiding in elevating the accuracy of flood forecasting. …”
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Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability by Valerie Haller, Carina Reiff, Rainer Hamacher, Karina Kostbade, Moritz Kaths, Juergen Treckmann, Stefanie Bertram, Yasmin Zaun, Sebastian Bauer, Johanna Falkenhorst

“…Conclusion In conclusion, this study provides a novel, real-world reference for survival outcomes in patients with metastatic GIST.…”
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BDMANGO: An image dataset for identifying the variety of mango based on the mango leavesMendeley Data by Mohammad Manzurul Islam, Md. Jubayer Ahmed, Mahmud Bin Shafi, Aritra Das, Md. Rakibul Hasan, Abdullah Al Rafi, Mohammad Rifat Ahmmad Rashid, Nishat Tasnim Niloy, Md. Sawkat Ali, Abdullahi Chowdhury, Ahmed Abdal Shafi Rasel

“…Both sides of each mango leaf were photographed against white background to accurately reflect real-world scenarios in mango cultivation fields. The white background was specifically chosen to remove noise in image sample, allowing for accurate feature extraction by machine learning algorithms. …”
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Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint by Yan Wang, Xiaoye Jin, Rui Qiu, Bo Ma, Sheng Zhang, Xuyang Song, Jinxi He

“…Application to TCGA data successfully predicted clinical outcomes, including a significant association with 6-month progression-free survival (PFS, P = 0.007, AUC = 0.793).DiscussionThe model demonstrates strong performance across preclinical datasets, showing its potential for real-world application in personalized cancer therapy. …”
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Swiss chiropractic practice-based research network and musculoskeletal pain cohort pilot study: protocol of a nationwide resource to advance musculoskeletal health services researc... by Milo A Puhan, Viktor von Wyl, Alice Kongsted, Cesar A Hincapié, Léonie Hofstetter, Rahim Lalji

“…While chiropractors often treat MSK conditions, there is limited real-world evidence on the topic of health service outcomes among patients receiving this type of care. …”
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Efficacy and Safety of Sofosbuvir-Based Direct-Acting Antiviral Agents Treatment for Patients with Genotype 3/6 Hepatitis C Virus Infection by Yong-yu Mei, You-ming Chen, Yuan-kai Wu, Xiao-hong Zhang, Wen-xiong Xu

“…Patients infected with GT 3/6 HCV and treated with SOF-based DAAs were enrolled in this prospective, open, single-center, and real-world study. Drugs included Sofosbuvir (SOF), Velpatasvir (VEL), Daclatasvir (DCV), and Ribavirin (RBV). …”
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Advancing breast cancer diagnosis: token vision transformers for faster and accurate classification of histopathology images by Mouhamed Laid Abimouloud, Khaled Bensid, Mohamed Elleuch, Mohamed Ben Ammar, Monji Kherallah

“…ViTs are notably recognized for their complex architecture, which requires high-performance GPUs or CPUs for efficient model training and deployment in real-world medical diagnostic devices. This renders them more intricate than convolutional neural networks (CNNs). …”
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Testbed Configuration for Minimizing PAPR in GFDM Systems Through a Novel Companding Approach by Sowbhagya Appalla, Siva Prasad Valluri, K. N. G. B. Yaswanth, Kishore Vejandla, Chakravarthy Gunturu, Gundla Jagapathi, Nittala Noel Anurag Prashanth, A. V. Prabu

“…To substantiate the theoretical and simulated outcomes, we have developed an experimental testbed leveraging the universal software radio peripheral (USRP) and LabVIEW environment, providing empirical validation and underscoring the real-world applicability of our proposed technique.…”
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On Robust Assembly of Flexible Flat Cables Combining CAD and Image Based Multiview Pose Estimation and a Multimodal Robotic Gripper by Junbang Liang, Joao Buzzatto, Bryan Busby, Haodan Jiang, Saori Matsunaga, Rintaro Haraguchi, Mariyama Toshisada, Bruce A. MacDonald, Minas Liarokapis

“…The results not only validate the feasibility of the proposed approach, but also demonstrate its robustness for real-world industrial applications.…”
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Comparison of Healthcare Encounters and Drug Persistence in Patients With Pulmonary Arterial Hypertension Receiving Oral Selexipag, Inhaled Iloprost, or Parenteral Treprostinil: A... by Ci Song, Peter Kunovszki, Amélie Beaudet

“…**Conclusions:** In real-world use, selexipag appears to be associated with lower rates of hospitalization and outpatient visits than inhaled iloprost or parenteral treprostinil. …”
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