Chronic Myeloid Leukemia: Part II—Cost of Care Among Patients in Advanced Phases or Later Lines of Therapy in Chronic Phase in the United States from a Commercial Perspective by Ehab L. Atallah, Rodrigo Maegawa, Dominick Latremouille-Viau, Carmine Rossi, Annie Guérin

“…**Objectives:** To describe real-world treatment patterns, healthcare resource utilization (HRU), and costs of patients with CML-CP reaching later lines of therapy or progressing to AP/BC in the United States. …”
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Multiple Comorbidities, Psychiatric Disorders, Healthcare Resource Utilization and Costs Among Adults with Essential Tremor: A Retrospective Observational Study in a Large US Comme... by Dingwei Dai, Ali Samiian, Joaquim Fernandes, Henriette Coetzer

“…**Conclusions:** This study represents the largest observational study to report ET disease and economic burdens in a real-world setting. The data demonstrate increased comorbidity, mental health, and healthcare cost burdens among ET patients compared with matched non-ET patients. …”
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Composites in high-pressure hydrogen storage: A review of multiscale characterization and mechanical behavior by Imen Feki, Mohammadali Shirinbayan, Samia Nouira, Robert Tie Bi, Jean-Baptiste Maeso, Cedric Thomas, Joseph Fitoussi

“…The study also examines residual properties following dynamic loading to provide a comprehensive understanding of long-term performance under real-world conditions. Findings emphasize the importance of multiscale coupling from macro to microstructure to achieve accurate modeling and prediction of composite behavior. …”
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Performance Understanding and Learning System (PULSE-KEY): development of a framework for implementation and performance evaluation of healthcare delivery models of care by Katrina L Campbell, Rumbidzai N Mutsekwa, Russell Canavan, Rebecca L Angus, Joshua Byrnes, Liza-Jane McBride

“…Building on this previous work, the present study advances the framework development through four additional stages: (4) development of a conceptual framework (identifying, categorising, synthesising concepts into outcome domains), (5) expert consultation, (6) validation using a real-world case study and (7) refinement for practical applicability and effectiveness in evaluating alternative healthcare delivery models of care.Results The framework was developed by synthesising insights from phases 1–3 of our previously published work and refined through consultations with 25 experts, confirming its relevance, clarity and suitability for diverse audiences. …”
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A dataset of annotated free comments on the sensory perception of madeleines for benchmarking text mining techniquesRecherche.Data.Gouv by Michel Visalli, Ronan Symoneaux, Cécile Mursic, Margaux Touret, Flore Lourtioux, Kipédène Coulibaly, Benjamin Mahieu

“…The dataset is based on real-world consumer data, showcasing how individuals naturally express their subjective perceptions. …”
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Challenges and opportunities for data integration to improve estimation of migratory connectivity by Jeffrey A. Hostetler, Emily B. Cohen, Christen M. Bossu, Amy L. Scarpignato, Kristen Ruegg, Andrea Contina, Clark S. Rushing, Michael T. Hallworth

“…We used simulation and real‐world case studies to explore the challenges and limitations of data integration based on data from three migratory bird species, Painted Bunting (Passerina ciris), Yellow Warbler (Setophaga petechia) and Bald Eagle (Haliaeetus leucocephalus), two of which had bidirectional data. …”
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Pengaruh Perkembangan Sastra Arab Pada Era 5.0 by Adelia Finanti

“…The development of digital-based technology has disrupted the flow of social interactions in the real world, and social interactions now only occur digitally. …”
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FedDrip: Federated Learning With Diffusion-Generated Synthetic Image by Karin Huangsuwan, Timothy Liu, Simon See, Aik Beng Ng, Peerapon Vateekul

“…In the realm of machine learning in healthcare, federated learning (FL) is often recognized as a practical solution for addressing issues related to data privacy and data distribution. However, many real-world datasets are not identically and independently distributed (non-IID). …”
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Trends in novel antiandrogen receptor signal inhibitor use and medical costs in prostate cancer by Hikari Miura, Hayato Yamamoto, Yoshiharu Okuyama, Noritaka Ishi, Ryuma Tanaka, Takuya Oishi, Fumiya Yoneyama, Tomoko Hamaya, Kyo Togashi, Naoki Fujita, Teppei Okamoto, Chikara Ohyama, Shingo Hatakeyama

“…Abstract Objective We aimed to examine trends in novel antiandrogen receptor signal inhibitor (ARSI) usage and medical costs by collecting real‐world big data included in The National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) Open Data, covering most of the clinical practices throughout Japan. …”
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Evaluating cyclic creep behavior of silicone-based thermoplastic elastomers for morphing control surface applications by Jeong-Hwan Yoon, Min-Jun Gim, Ye-Won Park, Yeon-Jee Cho, Kyoung-Ho Shin, Jae-Won Lee, Hui-Yeol Yun

“…A new cyclic creep test method for simulating real-world operational conditions for morphing control surfaces was proposed to evaluate the performance of these materials. …”
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Evidence Communication Rules for Policy (ECR-P) critical appraisal tool by Evangelos Danopoulos, John A. D. Aston, Aarushi Shah, Claudia R. Schneider

“…We encourage further independent testing of the tool in real-world evidence-based research.…”
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Comparative analysis of hull steel corrosion in tropical marine atmosphere: Correlation between indoor simulations and outdoor exposures by Feng Gao, Caifu Yang, Weiyi Wang, Yajun Pang, Naipeng Zhou, Jian Li, Xiaobing Luo, Feng Chai

“…Corrosion, a complex and gradual process, is best studied by directly exposing the materials to natural environments that closely mirror real-world conditions. However, this approach has limitations due to its lengthy testing periods and excessive costs. …”
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WIMUSim: simulating realistic variabilities in wearable IMUs for human activity recognition by Nobuyuki Oishi, Phil Birch, Daniel Roggen, Paula Lago

“…IntroductionPhysics simulation has emerged as a promising approach to generate virtual Inertial Measurement Unit (IMU) data, offering a solution to reduce the extensive cost and effort of real-world data collection. However, the fidelity of virtual IMU depends heavily on the quality of the source motion data, which varies with motion capture setups. …”
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Do current maternal health staffing and bed occupancy benchmarks work in practice? Results from a simulation model by Giorgia Gon, Carolin Vegvari, Rebecca F Baggaley, Said Mohammed Ali, Salma Abdi Mahmoud, Farhat Jowhar

“…We explore the potential impact of seasonality of births on our findings and then apply the model to a real-world setting using 2014 data from Emergency Obstetric Care (EmOC) facilities in Zanzibar, United Republic of Tanzania.Results We find that small EmOCs are frequently empty, while larger EmOCs are at risk of temporarily falling below minimum recommended staff-to-patient ratios. …”
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The role of artificial intelligence in pandemic responses: from epidemiological modeling to vaccine development by Mayur Suresh Gawande, Nikita Zade, Praveen Kumar, Swapnil Gundewar, Induni Nayodhara Weerarathna, Prateek Verma

“…It advocates for sustained research, real-world implications, ethical application and strategic integration of AI technologies to strengthen our collective ability to face and alleviate the effects of global health issues.…”
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Direct-supply chilled-water radiant-floor cooling system coupled with an earth‒air heat exchanger system: A case study in a building by Jiaming Yang, Huiqing Cao, Zhenwei Wang, Yue Liu, Wei Song, Jiankai Dong

“…In this study, a physical test was performed in a real-world application room, where the cooling and dehumidification characteristics of DS-RFC and EAHE systems were individually studied to evaluate their application potential. …”
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Can the adherence to quality of care indicators for early rheumatoid arthritis in clinical practice reduce risk of hospitalisation? Retrospective cohort study based on the Record L... by Carlo Alberto Scirè, Antonella Zambon, Greta Carrara, Anna Zanetti, Lisa Argnani

“…Objective To describe the adherence to quality of care indicators in early rheumatoid arthritis (RA) and to evaluate its impact on the risk of hospitalisation in a real-world setting.Design Retrospective cohort study.Setting Patients with early-onset RA identified from healthcare regional administrative databases by means of a validated algorithm between 2006 and 2012 in the Lombardy region (Italy).Participants The study cohort included 14 203 early-onset RA (71% female, mean age 60 years).Outcome measures For each patient, a summary adherence score was calculated starting from the compliance to six quality indicators: (1–2) methotrexate or sulfasalazine or leflunomide with/without glucocorticoids, (3–4) other disease-modifying antirheumatic drugs (DMARDs) with/without glucocorticoids, (5) early interruption of glucocorticoids, (6) early clinical assessment.The relationship between low, intermediate and high categories of the summary score and the 12-month risk of hospitalisation for all causes and for RA was assessed.Results During a follow-up of 1 year, 2609 hospitalisations occurred, of which 704 were for RA (main or secondary diagnosis) and 252 primarily for RA. …”
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MetaTrans-FSTSF: A Transformer-Based Meta-Learning Framework for Few-Shot Time Series Forecasting in Flood Prediction by Jiange Jiang, Chen Chen, Anna Lackinger, Huimin Li, Wan Li, Qingqi Pei, Schahram Dustdar

“…Our framework was evaluated using diverse datasets, including a real-world hydrological dataset from a small catchment area in Wuyuan, China, and other benchmark time series datasets. …”
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ISCAZIM: Integrated statistical correlation analysis for zero-inflated microbiome data by Zhe Fan, Jiali Lv, Shuai Zhang, Bingbing Gu, Cheng Wang, Tao Zhang

“…Applying to multiple real-world microbiome-metabolomics data, ISCAZIM is overall more accurate than using a single method with more truly significant association pairs included. …”
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Quinoid to benzenoid transition-driven glutathione sensing: Dual-emission carbon dots and smartphone-based ratiometric fluorescence analysis by Al-Montaser Bellah H. Ali, Ashraf M. Mahmoud, Yousef A. Bin Jardan, Aya M. Mostafa, James Barker, Mohamed M. El-Wekil

“…Practical validation using human serum samples demonstrated the method's robustness in complex biological matrices, achieving high recovery rates between 98.5 % and 101.0 %, confirming its suitability for real-world clinical applications. This novel strategy combines the sensitivity of ratiometric fluorescence with the convenience of smartphone-based detection, offering a promising tool for GSH monitoring in clinical and research settings.…”
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