Use of 18F-NaF PET in the staging of skeletal metastases of newly diagnosed, high-risk prostate cancer patients: a nationwide cohort study by Christian Torp-Pedersen, Mette Nørgaard, Helle D Zacho, Lars J Petersen, Anna Winther Mogensen, Marie T Pank

“…Objective To determine whether preoperative staging of high-risk prostate cancer with 18F-sodium-fluoride (18F-NaF) positron emission tomography (PET) reduces the risk of skeletal metastases.Design Nationwide, population-based cohort study using real-world data.Setting The study used national health registries, including all sites in Denmark from 2011 to 2018.Participants Newly diagnosed high-risk prostate cancer patients who underwent radical prostatectomy from 2011 to 2018. …”
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Implementation of an information system for tuberculosis in healthcare facilities in Indonesia: evaluation of its effectiveness and challenges by Rita Dian Pratiwi, Bachti Alisjahbana, Yanri Wijayanti Subronto, Sigit Priyanta, Suharna Suharna

“…Results The evaluation indicated that user convenience and timeliness require improvement, as well as the match between the system and the real world and error prevention, as shown in the heuristic evaluation of the SITB user interface. …”
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Digital health technologies and innovation patterns in diabetes ecosystems by Odile-Florence Giger, Estelle Pfitzer, Wasu Mekniran, Hannes Gebhardt, Elgar Fleisch, Mia Jovanova, Tobias Kowatsch

“…Results Our analyses revealed the emergence of eight organization segments in digital diabetes ecosystems: real-world evidence analytics, healthcare management platforms, clinical decision support, diagnostic and monitoring, digital therapeutics, wellness, online community, and online pharmacy (RQ1). …”
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An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets by Adam S. L. Graefe, Miriam R. Hübner, Filip Rehburg, Steffen Sander, Sophie A. I. Klopfenstein, Samer Alkarkoukly, Ana Grönke, Annic Weyersberg, Daniel Danis, Jana Zschüntzsch, Elisabeth F. Nyoungui, Susanna Wiegand, Peter Kühnen, Peter N. Robinson, Oya Beyan, Sylvia Thun

“…Our RD-CDM version 2.0.0 comprises 78 data elements, extending the ERDRI-CDS by 62 elements with previous versions implemented in four German university hospitals capturing real world data for development and evaluation. We identified three categories for evaluation: Medical Data Granularity, Clinical Reasoning and Medical Relevance, and Interoperability and Harmonisation.…”
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Compliant flooring to prevent fall-related injuries in older adults: A scoping review of biomechanical efficacy, clinical effectiveness, cost-effectiveness, and workplace safety. by Chantelle C Lachance, Michal P Jurkowski, Ania C Dymarz, Stephen N Robinovitch, Fabio Feldman, Andrew C Laing, Dawn C Mackey

“…Additional research is warranted to confirm whether compliant flooring (i) prevents fall-related injuries in real-world settings, (ii) is a cost-effective intervention strategy, and (iii) can be installed without negatively impacting workplace safety. …”
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Problem-based learning in developing students’ communicative skills and creativity in teaching English for specific purposes by Jolita Šliogerienė, Irena Darginavičienė, Jelena Suchanova, Dalia Gulbinskienė, Viktorija Jakučionytė

“… Tertiary education uses a variety of teaching methods to cater for different learning styles, encourage critical thinking, and prepare students for real-world challenges. Common methods include lectures, seminars, independent study, and collaborative learning. …”
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Healthcare Futures: Opportunities, Challenges and Risks in a Blockchain-Driven Environment by Robert Goldberg, Peter J. Pitts, Jennifer Hinkel

“…This approach not only ensures the continuity of value but also introduces a new financial layer that reflects the real-world impact of medical innovations. By using structured notes and algorithm-driven health indices, market participants can dynamically hedge against fluctuations in healthcare costs while aligning incentives across the healthcare value chain. …”
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Hybrid Modeling of an Induction Machine to Support Bearing Diagnostics by Praneet Amitabh, Dimitar Bozalakov, Frederik De Belie

“…Finally, the difference in the responses is reduced using the neural network such that it can mimic real-world machine behavior closely. The analytical model followed by statistical adjustment overall is considered a hybrid model. …”
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Multi-UAV Task Assignment in Dynamic Environments: Current Trends and Future Directions by Shahad Alqefari, Mohamed El Bachir Menai

“…It also introduces a comparative framework to evaluate algorithms based on metrics such as responsiveness, robustness, and scalability in handling real-world dynamic conditions. Our analysis reveals distinct strengths and limitations across three major approaches: market-based, intelligent optimization, and clustering-based solutions. …”
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A case study in statistical software development for advanced evidence synthesis: the combined value of analysts and research software engineers by Naomi Bradbury, Tom Morris, Clareece Nevill, Janion Nevill, Ryan Field, Suzanne Freeman, Nicola Cooper, Alex Sutton

“…Key challenges We discuss how we have addressed challenges to research software development such as responding to feedback from our real-world users to improve the CRSU apps, the implementation of software engineering principles into our app development process and gaining recognition for non-traditional research work within the academic environment. …”
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Estimation Model of Global Ionospheric Irregularities: An Artificial Intelligence Approach by Penghao Tian, Bingkun Yu, Hailun Ye, Xianghui Xue, Jianfei Wu, Tingdi Chen

“…Abstract The ionospheric sporadic E layer, the ionospheric irregularities of enhanced electron density, appears in the Earth's ionosphere at altitudes between 90 and 120 km, which supports the real‐world radio communication needs of many sectors reliant on ionosphere‐dependent decision‐making. …”
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“site suitability analysis for integrating large-scale hybrid photovoltaic and concentrated solar power plants in Cameroon using Monte Carlo, analytic hierarchy process, and geogra... by Fotsing Metegam Isabelle Flora

“…The methodology was validated by comparing the suitability maps with real-world solar plants in Guider and Maroua, which were located in highly suitable areas, supporting the model’s accuracy. …”
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Enhancing prehospital decision-making: exploring user needs and design considerations for clinical decision support systems by Enze Bai, Zhan Zhang, Yincao Xu, Xiao Luo, Kathleen Adelgais

“…However, such systems have not yet been widely adopted in real-world practice and have been found to cause workflow disruptions and usability issues. …”
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Electromagnetic metamaterial agent by Shengguo Hu, Mingyi Li, Jiawen Xu, Hongrui Zhang, Shanghang Zhang, Tie Jun Cui, Philipp del Hougne, Lianlin Li

“…In response to live environmental feedback within a real-world setting emulating an ambient-assisted living context (including human requests in natural language), our metaAgent prototype self-organizes a hierarchy of EM manipulation tasks in conjunction with commanding a robot. metaAgent masters foundational EM manipulation skills related to wireless communications and sensing, and it memorizes and learns from past experience based on human feedback.…”
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SMOTE vs. SMOTEENN: A Study on the Performance of Resampling Algorithms for Addressing Class Imbalance in Regression Models by Gazi Husain, Daniel Nasef, Rejath Jose, Jonathan Mayer, Molly Bekbolatova, Timothy Devine, Milan Toma

“…This bias can significantly undermine accurate predictions in real-world scenarios, highlighting the importance of the robust handling of imbalanced data for dependable results. …”
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Adaptation and uptake evaluation of an SMS text message smoking cessation programme (MiQuit) for use in antenatal care by Felix Naughton, Stephen Sutton, Tim Coleman, Sue Cooper, Jo Leonardi-Bee, Katharine Bowker, Katarzyna Campbell, Melanie Sloan

“…Objectives To adapt a tailored short message service (SMS) text message smoking cessation intervention (MiQuit) for use without active health professional endorsement in routine antenatal care settings, to estimate ‘real-world’ uptake and test the feasibility of its use.Design Single-site service evaluation.Setting A Nottinghamshire (UK) antenatal clinic.Participants Pregnant women accessing the antenatal clinic (N=1750) over 6 months.Intervention A single-sheet A5 leaflet provided in the women's maternity notes folder describing the MiQuit text service. …”
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metaRange: A framework to build mechanistic range models by Stefan Fallert, Lea Li, Juliano Sarmento Cabral

“…We believe that it allows for theoretical insights and hypotheses testing about future range dynamics of real‐world species, which may better support conservation policies targeting biodiversity loss mitigation.…”
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Developing an Ethical Regulatory Framework for Artificial Intelligence: Integrating Systematic Review, Thematic Analysis, and Multidisciplinary Theories by Jian Wang, Yujia Huo, Jinli Mahe, Zongyuan Ge, Zhangdaihong Liu, Wenxin Wang, Lin Zhang

“…However, translating these principles into concrete, real-world applications for AI development remains a pressing need and a significant challenge. …”
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Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors by Callisia N. Clarke, Paul Cockrum, Thomas J.R. Beveridge, Michelle Jerry, Donna McMorrow, Anh Thu Tran, Alexandria T. Phan

“…Results for switched treatment patterns were limited due to insufficient sample sizes. **Discussion:** Real-world treatment patterns of LA-SSA were assessed using more recent administrative claims data. …”
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Advancing Anaesthetist Rostering Quality: A Practical Approach Toward Fairness and Efficiency by Norizal Abdullah, Masri Ayob, Meng Chun Lam, Nasser R. Sabar, Graham Kendall, Liu Chian Yong

“…Existing models for the ARP often fail to address the complexities of real-world hospital environments, particularly in integrating monthly and weekly schedules across multiple locations. …”
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