Energy-based approach to the assessment of traffic flow by Volodymyr Polishuk, Stanislav Popov, Inna Vyhovska, Serhii Yanishevskiy, Liudmyla Nahrebelna

“…The proposed model has been validated using real-world data. It demonstrates a strong correlation between the predictions and actual vehicle behavior on various road types. …”
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Generalizability of Randomized Clinical Trial Outcomes for Diabetes Control Resulting From Bariatric Surgery by Edward H. Livingston, MD, FACS, AGAF, Hila Zelicha, RD, PhD, Erik P. Dutson, MD, Zhaoping Li, MD, PhD, Matthew L. Maciejewski, PhD, Yijun Chen, MD

“…However, characteristics of trial participants may not be representative of patients receiving treatment in the real world. There is a need to assess how the results of RCTs generalize to all contemporary patient populations undergoing treatments. …”
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Development of measures to assess listening-related effort and fatigue in daily life among hearing aid users: protocol for a quantitative field trial by Trine Flensborg-Madsen, Andreea Micula, Jeppe Høy Konvalinka Christensen, Dorothea Wendt, Hamish Innes-Brown, Ingrid Johnsrude, Matthew Apps, Torsten Dau

“…However, there is a lack of objective measures to evaluate these experiences in real-world settings. Recent studies have found that higher sound pressure levels (SPL) and lower signal-to-noise ratios (SNR) are linked to increased heart rate and decreased heart rate variability, reflecting the greater effort required to process auditory information. …”
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Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology by Matteo P. Ferla, Rubén Sánchez-García, Rachael E. Skyner, Stefan Gahbauer, Jenny C. Taylor, Frank von Delft, Brian D. Marsden, Charlotte M. Deane

“…This method has had a prior real-world application in hit-to-lead screening, yielding a sub-micromolar merger from parent hits in a single round. …”
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Multi-view knowledge representation learning for personalized news recommendation by Chao Chang, Feiyi Tang, Peng Yang, Jingui Zhang, Jingxuan Huang, Junxian Li, Zhenjun Li

“…Extensive experiments on three real-world datasets demonstrate that our proposed framework outperforms state-of-the-art baselines in recommendation accuracy, validating its effectiveness.…”
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Acromegaly: Is earlier diagnosis possible? Exploration of a screening algorithm to select high-risk patients by Tessa N.A. Slagboom, David de Jong, Peter H. Bisschop, Madeleine L. Drent

“…Multiple sources (literature review, real-world evidence and expert opinion) were used to identify predictors such as clinical manifestations, comorbidities and frequently consulted specialists, for inclusion in the algorithm. …”
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Performance Evaluation of Machine Learning Models for Predicting Energy Consumption and Occupant Dissatisfaction in Buildings by Haidar Hosamo, Silvia Mazzetto

“…Future research should validate these findings with diverse real-world datasets, including those representing varying building types and climates. …”
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Are we ready for the new normal in e-business education? Sentiment analysis of learners' opinions on MOOCs by O. F. Derindag, B. Cizmeci

“…Distance learning has become an indispensable alternative teaching method in updating and transferring classical education materials according to real-world settings, especially for learners in higher education.Aim. …”
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A 2-Year, Phase IV, Multicentre, Observational Study of Ranibizumab 0.5 mg in Patients with Neovascular Age-Related Macular Degeneration in Routine Clinical Practice: The EPICOHORT... by Sergio Pagliarini, Stephen Beatty, Blandina Lipkova, Eduardo Perez-Salvador Garcia, Stefaan Reynders, Margarita Gekkieva, Abdelkader Si Bouazza, Stefan Pilz

“…This 2-year, multicentre, observational study was conducted to capture real-world early practice and outcomes across Europe, shortly after European licensing of ranibizumab for nAMD. …”
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Integrating Visible Light Communication and AI for Adaptive Traffic Management: A Focus on Reward Functions and Rerouting Coordination by Manuela Vieira, Gonçalo Galvão, Manuel A. Vieira, Mário Vestias, Paula Louro, Pedro Vieira

“…Simulation experiments in the SUMO urban mobility simulator and real-world trials validate the system across diverse intersection types, including four-way crossings, T-intersections, and roundabouts. …”
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Predictive Forwarding Rule Caching for Latency Reduction in Dynamic SDN by Doosik Um, Hyung-Seok Park, Hyunho Ryu, Kyung-Joon Park

“…The GCS and nodes exchange different types of information, including control data that direct unmanned vehicle movements and sensor data that capture real-world environmental conditions. The GCS and nodes communicate wirelessly, leading to loss or delays in control and sensor data. …”
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Effectiveness and Safety of Dupilumab and Tralokinumab for Treating Atopic Dermatitis and Pruritic Skin Disorders in Oncological Patients: A Narrative Review by Lauletta G, Potestio L, Patruno C, De Lucia M, Napolitano M

“…Although there are no explicit contraindications for using dupilumab and tralokinumab in patients with active cancer or a history of malignancy, there is no definitive guidance on their use in such cases. Real-world data is emerging, facilitated by collaboration between dermatologists and oncologists, supporting the effectiveness and safety of dupilumab and tralokinumab for managing AD in cancer patients. …”
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Highway Travel Time Prediction of Segments Based on ANPR Data considering Traffic Diversion by Wenjun Du, Bo Sun, Jiating Kuai, Jiemin Xie, Jie Yu, Tuo Sun

“…The proposed LSTM-CNN approach is tested on the three-month ANPR data of a real-world 39.25 km highway with four pairs of ANPR detectors of the uplink and downlink, Zhejiang, China. …”
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Multimodal Fusion and Cutting-Edge AI-Based Smart Vending Machines for Electronic Component Management by M. Karthiga, Syarifah Bahiyah Rahayu, E. Suganya, S. Sankarananth, S. Sountharrajan, K. Venkatesan

“…Furthermore, the vending machine’s digital twin accurately simulates its real-world performance for virtual testing and improvement prior to real deployment, offering increased effectiveness and convenience.…”
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Q-learning global path planning for UAV navigation with pondered priorities by Kevin B. de Carvalho, Hiago de O.B. Batista, Leonardo A. Fagundes-Junior, Iure Rosa L. de Oliveira, Alexandre S. Brandão

“…To further validate the proposed approach, both simulations and real-world experiments are employed, collectively demonstrating its performance and applicability.…”
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Using Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) in Obese Patients: A Real-Life, Single-Center Observational Study by Alessandra Oliva, Flavia Petrucci, Cristiana Leanza, Marco Rivano Capparuccia, Michela Comi, Claudio Mastroianni

“…<b>Conclusions</b>: In our real-world study, DAL confirmed its high effectiveness in the treatment of ABSSSI, including in a difficult-to-treat population such as obese patients.…”
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Efficiency of Real-time Computer-aided Polyp Detection during Surveillance Colonoscopy: A Pilot Study by Shin Morimoto, Hidenori Tanaka, Yudai Takehara, Noriko Yamamoto, Fumiaki Tanino, Yuki Kamigaichi, Ken Yamashita, Hidehiko Takigawa, Yuji Urabe, Toshio Kuwai, Shiro Oka

“…Objectives: Studies have suggested that computer-aided polyp detection using artificial intelligence improves adenoma identification during colonoscopy. However, its real-world effectiveness remains unclear. Therefore, this study evaluated the usefulness of computer-aided detection during regular surveillance colonoscopy. …”
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The philosophical foundations of digital twinning by David J Wagg, Christopher Burr, Jason Shepherd, Zack Xuereb Conti, Mark Enzer, Steven Niederer

“…Digital twins are a new paradigm for our time, offering the possibility of interconnected virtual representations of the real world. The concept is very versatile and has been adopted by multiple communities of practice, policymakers, researchers, and innovators. …”
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Interface-engineered non-volatile visible-blind photodetector for in-sensor computing by Ge Li, Donggang Xie, Qinghua Zhang, Mingzhen Zhang, Zhuohui Liu, Zheng Wang, Jiahui Xie, Erjia Guo, Meng He, Can Wang, Lin Gu, Guozhen Yang, Kuijuan Jin, Chen Ge

“…The location and classification of corona discharges in real-world environments were also simulated and achieved an accuracy of 100%. …”
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Ocrelizumab-induced colitis—critical review and case series from a Romanian cohort of MS patients by Ileana Maria Vodă, Vlad Eugen Tiu, Vlad Eugen Tiu, Luiza Răuță, Paul Ciucur, Andreea Ioana Mușuroi, Alina Flavia Tomescu, Alina Flavia Tomescu, Nicoleta Laura Humă, Florin Dobrițoiu, Florin Dobrițoiu, Elena Terecoasă, Elena Terecoasă, Lucian Negreanu, Lucian Negreanu, Cristina Tiu, Cristina Tiu

“…BackgroundWidespread use of ocrelizumab, an anti-CD20 monoclonal antibody, for treating patients with multiple sclerosis (MS), has led to an increase in reported adverse events following real-world observation. Among these, drug-induced colitis is a rare, but severe side effect, prompting a recent FDA statement regarding this safety concern. …”
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