Wilson disease in the USA: epidemiology and real-world patient characteristics based on a retrospective observational health claims study by Karl Heinz Weiss, Peter Hedera, Shona Fang, Carey Strader, Halley Costantino

“…The 2017–2019 crude period prevalence was 21.2 patients per million (95% CI: 20.1 to 22.3), with similar prevalence observed for both sexes.Conclusions This study provides important real-world data on the diagnosed prevalence of WD in the USA and revealed the comorbidities associated with various disease subtypes, thereby providing a comprehensive basis for guiding physicians and policy makers in the management of this chronic disease.…”
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TERTp Mutation and its Prognostic Value in Glioma Patients Under the 2021 WHO Classification: A Real‐World Study by Hao Xing, Delin Liu, Junlin Li, Yulu Ge, Xiaopeng Guo, Wenlin Chen, Dachun Zhao, Yixin Shi, Yilin Li, Yaning Wang, Yuekun Wang, Yu Xia, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Siying Guo, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma

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Real-World Treatment Outcomes of an Artificial Tear Containing Arabinogalactan, Hyaluronic Acid and Trehalose Among Subjects with Dry Eye by Bedei A, Rocha Cabrera P, Oliveira L, Castellini L, De Grazia G, Remiddi S

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A real-world analysis of antidepressant medications in US veterans aged 60 years and older: a comparative analysis by Ryan D Pittman, S Scott Sutton, Joseph Magagnoli, Tammy H Cummings

Real-World Efficacy and Safety of Tafluprost in Primary Open-Angle Glaucoma Patients with Corneal Disorders: A Taiwan Experience by Ju-Kuo Lin, Fu-Tsung Wei, Yi-Chun Liu, Yung-Chang Yen

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Long-Term Survival and Risk Factors in Patients with Hepatitis B-Related Hepatocellular Carcinoma: A Real-World Study by Yu Zhu, Ling-Ling Gu, Fa-Biao Zhang, Guo-Qun Zheng, Ting Chen, Wei-Dong Jia

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A Real-World, Multicenter Assessment of Drugs Requiring Weight-Based Calculations in Overweight, Adult Critically Ill Patients by Sandra L. Kane-Gill, Nicholas P. Wytiaz, Lisa M. Thompson, Karina Muzykovsky, Mitchell S. Buckley, Henry Cohen, Amy L. Seybert

“…The purpose of this study was to identify “real-world” dose ranges of high-risk medications administered via continuous infusion requiring weight-based dosing and determine the reasons for dosing changes (ineffectiveness or adverse drug reactions). …”
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Efficacy and Safety of Immunosuppressive Therapy for PBC–AIH Overlap Syndrome Accompanied by Decompensated Cirrhosis: A Real-World Study by Xiaoli Fan, Yongjun Zhu, Ruoting Men, Maoyao Wen, Yi Shen, Changli Lu, Li Yang

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Cost–Benefit Analysis of in vivo Reflectance Confocal Microscopy for Melanoma Diagnosis in a Real-World Clinical Setting by Bruno GM, Di Matteo S, Longo C, Stanganelli I, Farnetani F, Borsari S, Mazzoni L, Ciardo S, Raucci M, Magi S, Bassoli S, Spadafora M, Mandel VD, Casari A, Chester J, Kaleci S, Colombo GL, Pellacani G

“…The cost–benefit ratio for RCM was 3.89, meaning that for every € 1 spent on RCM, there is a benefit of € 3.89.Conclusion: In real-world clinical practice, adjunctive RCM offers significant economic advantages at local, regional, and national levels while maintaining patient safety and reducing unnecessary surgical procedures.Keywords: melanoma, dermoscopic examination, reflectance confocal microscopy, cost–benefit, economics, cost analysis, skin cancers…”
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The interface of real world, lexicalization and conceptualization on the example of the Contact Sense of the German preposition an (on, at) and its Polish Spanish and English counterparts by Jolanta Mazurkiewicz-Sokołowska

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Long-Term efficacy and safety analysis of secukinumab in the treatment of pediatric generalized pustular psoriasis: a real-world study by Lu Xing, Lingsheng Long, Tao Wu, Lingrui Yin, Li Yu, Jingnan Wu, Danchen Li, Limin Miao, Hong Shu

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Drug-induced dementia: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System database by Lisi Xu, Ruonan Zhang, Xiaolin Zhang, Xiuli Shang, Daifa Huang

“…FDA Adverse Event Reporting System (FAERS) serves as an important resource for identifying real-world adverse drug reactions and safety signals. …”
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The Real-World Utilization Pattern of Increased Utilization of Advanced Topical Adjunctive Hemostats in a Vertically Integrated Healthcare System by Lee Stern, Yi-Chien Lee, Biwen Tao, Lois Lamerato, Gaurav Gangoli, Richard Kocharian, Walter Danker III

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Real-world effectiveness of Semaglutide treatment on weight loss maintenance after weight loss in patients with obesity or overweight and diabetes by Michela Del Prete, Lidia Gavazzi, Olga Eugenia Disoteo, Federico Vignati, Gianleone Di Sacco, Fabrizio Muratori

“…Abstract Purpose To report data on the real-world effectiveness and safety of injectable (IS) and oral (OS) therapies in obese or overweight diabetes (T2DM) patients on glycometabolic control, weight loss (WL) and weight maintenance after the use of semaglutide. …”
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Real-world effectiveness of intravenous belimumab in adults with systemic lupus erythematosus: results of the observational OBSErve study in the Russian Federation by Alexander Mikhailovich Lila, Elena Aleksandrovna Aseeva, Alyona Igorevna Zagrebneva, Irina Borisovna Vinogradova, Ruzana Ramilovna Samigullina, Munther Khamashta, Tamer Elfishawy, Lindsey Teichman, Debora dos Santos, Juliana Queiroz, Larisa Alexandrovna Kniazeva, Saeed Noibi

“…Here we describe the clinical effectiveness of IV belimumab for treating SLE in real-world clinical practice in the Russian Federation. …”
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Integrating Explainable Artificial Intelligence With Advanced Deep Learning Model for Crowd Density Estimation in Real-World Surveillance Systems by Sultan Refa Alotaibi, Hanan Abdullah Mengash, Mohammed Maray, Faiz Abdullah Alotaibi, Abdulwhab Alkharashi, Ahmad A. Alzahrani, Moneerah Alotaibi, Mrim M. Alnfiai

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Real-World Experience with AGA Guidelines in the Management of Crohn’s Disease following Ileocolonic Resection: A Retrospective Cohort Study by Shasha Tang, Wei Liu, Weilin Qi, Tunan Yu, Qian Cao, Xiaolong Ge, Wei Zhou

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Safety and effectiveness of an herbal decoction (modified Saengmaeksan) in hypertensive patients: Protocol for a real-world prospective observational study. by Nahyun Cho, Hobin Moon, Kyung-Min Shin, Byoung-Kab Kang, Jungtae Leem, Changsop Yang

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Real World Experience of Chronic Hepatitis C Retreatment with Genotype Specific Regimens in Nonresponders to Previous Interferon-Free Therapy by Dorota Zarębska-Michaluk, Iwona Buczyńska, Krzysztof Simon, Magdalena Tudrujek-Zdunek, Ewa Janczewska, Dorota Dybowska, Marek Sitko, Beata Dobracka, Jerzy Jaroszewicz, Paweł Pabjan, Jakub Klapaczyński, Łukasz Laurans, Włodzimierz Mazur, Łukasz Socha, Olga Tronina, Miłosz Parczewski, Robert Flisiak

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Early OCT Angiography Changes of Macular Neovascularization in Patients with Exudative AMD Treated with Brolucizumab in a Real-World Setting by Anne Rübsam, Saskia Rau, Daniel Pilger, Oliver Zeitz, Antonia M. Joussen

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