Superficial Siderosis and Anticoagulation Therapy: Different Presentations, Different Outcomes by Rui Duarte Barreto, Luís Ruano, Vítor Tedim Cruz, Carlos Veira, Paula Coutinho

“…Two Caucasian women, both under long-term oral anticoagulation: a 74 year old woman with slowly progressive hearing loss and mild cerebellar ataxia; a 72 year old woman suffering from behavioural changes, rapidly progressive cognitive decline and latter developing paraparesis. …”
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Clinical Application of Autologous Adipose Stem Cells in Patients with Multiple Sclerosis: Preliminary Results by Adam Stepien, Natalia L. Dabrowska, Marzena Maciagowska, Renata Piusinska Macoch, Aleksandra Zolocinska, Slawomir Mazur, Katarzyna Siennicka, Emilia Frankowska, Rafał Kidzinski, Małgorzata Chalimoniuk, Zygmunt Pojda

“…Our results indicate that ASC therapy is safe and does not produce any substantial side effects. Disease progression-free survival (PFS) of 18 months was seen in all patients with RRMS and SPMS. …”
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Bimelic Hirayama Disease: Clinical Dilemma Solved by Imaging by Shalabh Jain, Siddharth Yadav, Swarna Gupta, Ritu Gupta

“…It is characterized by progressive muscular weakness and atrophy of unilateral or asymmetrically bilateral distal upper limbs. …”
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The Emerging Role of GC-MSCs in the Gastric Cancer Microenvironment: From Tumor to Tumor Immunity by Zhaoji Pan, Yiqing Tian, Guoping Niu, Chengsong Cao

“…Mesenchymal stem cells (MSCs) have been declared to not only participate in wound repair but also affect tumor progression. Tumor-associated MSCs, directly existing in the tumor microenvironment, play a critical role in tumor initiation, progression, and development. …”
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The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke by Nada H. Aljarba, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Mustafa M. Shokr, Marios Papadakis, Athanasios Alexiou, Mubarak Alruwaili, Mohammed Alrouji, Mohammed S. Alshammari, Gaber El-Saber Batiha

“…AGEs promote the generation of reactive oxygen species that induce the release of pro-inflammatory cytokines, and alter the intracellular signaling leading to progressive biochemical and metabolic derangements. …”
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Liver Infarction in a Patient with HELLP and Probable Anti-phospholipid Syndrome by Cihan Kaya, Hüseyin Cengiz, Murat Ekin, Ammar Kanawati, Levent Yaşar

“… The aim of this report is to make an awareness about hepatic infarction in those patients with progressively elevating liver enzymes and anti-phospholipid syndrome. …”
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An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature by Yiqiao Wang, Andre Le, Dina El Demellawy, Mary Shago, Michael Odell, Stephanie Johnson-Obaseki

“…Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. …”
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Alström’s Syndrome, Leber’s Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis by Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos

“…AS affects metabolism, and symptomatology includes type 2 diabetes mellitus (T2DM), obesity, hypogonadism and gynecomastia in males, progressive bilateral sensorineural hearing loss, cardiomyopathy, nonalcoholic fatty liver disease (NAFLD), cirrhosis, and chronic progressive kidney disease. …”
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The environmental price of socio-economic development: Worldwide trends from 1990 to 2016 by Katja VINTAR MALLY

“… Plans for achieving sustainable development around the world are based on the assumption that socio-economic progress can be ensured only by staying within the carrying capacity of the environment, which has already been exceeded in a number of areas. …”
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Daratumumab, Lenalidomide, and Dexamethasone (DRD), an Active Regimen in the Treatment of Immunosuppression-Associated Plasmablastic Lymphoma (PBL) in the Setting of Gorham’s Lymph... by Matthew Lee, Beth A. Martin, Haifaa Abdulhaq

“…We present a 23-year-old HIV-negative woman with GSD, managed medically with octreotide and sirolimus, who developed PBL. After progressing on V-EPOCH (bortezomib, etoposide, vincristine, cyclophosphamide, doxorubicin, and prednisone), she was treated with daratumumab, lenalidomide, and dexamethasone (DRD) therapy and achieved complete remission after two cycles with progression after eight cycles. …”
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Setting Them Up To Fail by David Allan

“… This paper looks at post-16 progression opportunities for a group of previously disaffected 14–16-year-old students who undertook vocational learning in their final two years at school in the north-west of England. …”
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Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study by Zhongguang Luo, Wenshuai Li, Wanwei Zheng, Yixiang Shi, Maolin Ye, Xiangyu Guo, Kaiyi Fu, Changsheng Yan, Bowen Wang, Bin Lv, Shaocong Mo, Hongyang Zhang, Jun Zhang, Chuan He, Feifei Luo, Wei Zhang, Jie Liu

“…Genome‐wide mapping of 5hmC in gastric premalignant lesions from a subset of individuals was performed using the 5hmC‐Seal assay, including 21 samples that progressed to GAC during follow‐up and 48 non‐progressed age‐ and sex‐matched controls. …”
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Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis by Lihong Yang, Hongxun Li, Xinheng Zhao, Ye Pan

“…We performed a systematic review and meta-analysis to evaluate the association between cataract surgery and the development and progression of AMD. Methods. This meta-analysis was registered at PROSPERO (CRD42017077962). …”
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The prognostic effect of immunohistochemical staining rates in patients with non–muscle-invasive bladder cancer by Aykut Demirci, Melike Ordu

“…Recurrence rate was determined to be 36% (n = 32), and the rate of progression at 40.4% (n = 36). The staining rates were stronger for each marker in the progression group and advanced-stage tumors (p < 0.001). …”
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Introducing an ensemble method for the early detection of Alzheimer's disease through the analysis of PET scan images by Arezoo Borji, Taha-Hossein Hejazi, Abbas Seifi

“…Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. …”
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Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease by O. Yu. Kytikova, T. P. Novgorodtseva, Yu. K. Denisenko, D. A. Kovalevsky

“…To present literature data on the metabolic and genetic mechanisms of impaired fatty acid (FA) synthesis in the development and progression of non-alcoholic fatty liver disease (NAFLD).General findings. …”
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Application of educational data mining in subject learning at university by Irina A. Kotiurova

“…The feasibility of big data collection in the form of students' work in progress has been confirmed, which can then be effectively applied in teaching. …”
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HIV-Associated Vacuolar Myelopathy and HIV-Associated Dementia as the Initial Manifestation of HIV/AIDS by Natalia Wuliji, Matthew J. Mandell, Jason M. Lunt, Adam Merando

“…HIV-associated vacuolar myelopathy (HIV-VM) is the most common cause of spinal disease in HIV/AIDS. HIV-VM causes progressive spastic paraparesis, sensory ataxia, and autonomic dysfunction. …”
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Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomics by Yin Le, Shicong Zhu, Hongling Peng, Zhihua Wang

“…Our findings indicate that the PI3K-Akt signaling pathway is significantly enriched across all groups, highlighting its critical role in B-ALL pathogenesis and progression. Furthermore, metabolomic analysis revealed that lipid metabolism, ferroptosis, and glutathione metabolism are closely linked to disease progression. …”
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Recent Advances and Perspectives on the Use of Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Chronic Kidney Disease: A Review by Kisho Miyasako, Yujiro Maeoka, Takao Masaki

“…It is a significant risk factor for cardiovascular disease (CVD), and, as it progresses, the risk of cardiovascular events increases. …”
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