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17301
Development of machine learning models for diagnostic biomarker identification and immune cell infiltration analysis in PCOS
Published 2025-01-01“…Furthermore, the analysis of immune cell infiltration revealed the significant involvement of CD4 memory resting T cells in the onset and progression of PCOS. These findings shed light on potential mechanisms underlying PCOS pathogenesis and provide valuable insights for future research and therapeutic interventions.…”
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17302
Risk Factors and Outcome of Sepsis in Traumatic Patients and Pathogen Detection Using Metagenomic Next-Generation Sequencing
Published 2022-01-01“…Once diagnosed with sepsis, patients should be given an appropriate empiric antimicrobial treatment followed by the specific antibiotic therapy based on blood culture due to its rapid progression to tissue damage and organ failure. In this study, we aimed to analyze the risk factors and outcome of sepsis in traumatic patients and to investigate the performance of metagenomic next-generation sequencing (mNGS) compared with standard microbiological diagnostics in post-traumatic sepsis. …”
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17303
Central corneal thickness to adjust IOP measurements
Published 2020-03-01“…Data on CCT as a risk factor for glaucoma development and progression are addressed. The article discusses the effect of CCT on the readings of various methods of tonometry. …”
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17304
Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis Through HGF/YAP Signaling Pathway
Published 2024-11-01“…Background and objective The early stages of tumor bone metastasis are closely associated with changes in the vascular niche of the bone microenvironment, and abnormal angiogenesis accelerates tumor metastasis and progression. However, the effects of lung adenocarcinoma (LUAD) cells reprogrammed by the bone microenvironment on the vascular niche within the bone microenvironment and the underlying mechanisms remain unclear. …”
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17305
Carotenoids in the treatment of age-related macular degeneration: a drug delivery system does matter
Published 2023-03-01“…Carotenoids lutein and zeaxanthin are natural compounds with a proven efficacy in reducing AMD progression, which have been demonstrated to act as medications for patients with early AMD stages. …”
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17306
Correlations of Cancer-Related Fatigue with Clinicopathological Features and Quality of Life in Gastric Cancer
Published 2024-01-01“…After chemotherapy, the average CRF BFI scores of the partial remission (PR), disease stability (SD), and disease progression (PD) groups all reduced than those before chemotherapy (all P<0.05). …”
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17307
Visual analysis of research hotspots and trends in traditional Chinese medicine for depression in the 21st century: A bibliometric study based on citespace and VOSviewer
Published 2025-01-01“…Therefore, the present study aimed to summarise the research trends and progress in this field, providing relevant information and presenting potential future research directions for subsequent researchers. …”
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17308
Détermination du statut du Chimpanzé, Pan troglodytes verus, dans une zone non protégée de savane boisée à Bagnomba, Sénégal : Implication pour sa conservation
Published 2016-01-01“…Actuellement, la dégradation des habitats du chimpanzé au Sénégal ne cesse de progresser en raison d’effets anthropiques et de changements climatiques. …”
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17309
Long-Term Treatment Outcomes of Micropulse Transscleral Cyclophotocoagulation in Primary and Secondary Glaucoma: A 5-Year Analysis
Published 2024-12-01“…In patients with a preoperative Central Distance Visual Acuity (CDVA) > 0.05 on the Snellen chart, more than two lines of visual acuity (VA) loss were attributed to cataract (n = 10), retinal disease (n = 5), glaucoma progression (n = 3), corneal decompensation (n = 2), or other factors (n = 11). …”
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17310
Genomic strategies to facilitate breeding for increased β-Glucan content in oat (Avena sativa L.)
Published 2025-01-01“…To maximize health benefits associated with the consumption of oat-based food products, breeding efforts have aimed at increasing the β-glucan content in oat groats. However, progress has been limited. To accelerate oat breeding efforts, we leveraged existing breeding datasets (1,230 breeding lines from South Dakota State University oat breeding program grown in multiple environments between 2015 and 2022) to conduct a genome-wide association study (GWAS) to increase our understanding of the genetic control of beta-glucan content in oats and to compare strategies to implement genomic selection (GS) to increase genetic gain for β-glucan content in oat. …”
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17311
Fine particulate matter concentrations forecasting using long short-term memory network and meteorological inputs
Published 2024-10-01“…It has effectively surpassed the constraint of collecting observable data, attaining minimal error values on both sensors and satellite data, signifying a noteworthy progression compared to previous studies. Therefore, it might benefit areas lacking sufficient data, providing a valuable tool for air pollution mitigation.…”
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17312
Conditional cash transfer program and child mortality: A cross-sectional analysis nested within the 100 Million Brazilian Cohort.
Published 2021-09-01“…<h4>Background</h4>Brazil has made great progress in reducing child mortality over the past decades, and a parcel of this achievement has been credited to the Bolsa Família program (BFP). …”
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17313
Mechanisms of the Effect of Starvation Duration on the Regulation of Feeding Rhythm and Metabolic Physiology of Cultured Large Yellow Croaker (<i>Larimichthys crocea</i>)
Published 2025-01-01“…In recent years, significant progress has been made in China in the field of deep-sea large yellow croaker (<i>Larimichthys crocea</i>) farming. …”
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17314
Functional Near-Infrared Brain Network Characteristics Analysis in Patients with Cognitive Impairment after Stroke
Published 2024-08-01“…Altered functional connectivity patterns of SEN-FPN may be closely related to the occurrence and progression of PSCI, and changes in functional connectivity strength of SEN-FPN may be a potential imaging indicator of PSCI.…”
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17315
Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection
Published 2025-02-01“…Inflammation is a critical mechanism in the development of AD, and identifying specific molecular targets to regulate inflammation is crucial for stopping its progression. This study aimed to investigate the role of MR-1 and ROCK1 in the regulation of inflammation in AD and their potentialities as therapeutic targets.Methods: Researchers performed protein immunoblotting on aortic wall tissue from 10 patients who underwent aortic arch replacement and 10 patients who underwent coronary artery bypass grafting to examine the expression levels of MR-1, ROCK1, and inflammatory pathways in the aortas. …”
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17316
Four weeks of slow-paced breathing: a longitudinal, randomized, placebo-controlled study of the autonomic nervous system
Published 2025-01-01“…The amplitude of RSA is modified by the respiratory frequency, i.e. an increase in respiratory frequency leads to a progressive decline in RSA as vagal effectors become less able to follow variations at higher frequencies. …”
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17317
Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing
Published 2024-01-01“…In clinical practice, BRAFV600E mutation does not consistently serve as an effective biomarker to distinguish high-risk PTMC or predict tumor progression. The size of the tumor has a significant correlation with its aggressive characteristics. …”
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17318
The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study
Published 2025-02-01“…The use of actigraphy with different algorithms to evaluate sleep and circadian rhythm after acute MI has the potential for predicting outcomes and preventing future disease progression. ObjectiveWe aimed to evaluate how sleep patterns and disrupted circadian rhythm affect the prognosis of MI, using actigraphy and heart rate variability (HRV). …”
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17319
AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can...
Published 2025-01-01“…Abstract Background Most patients with prostate cancer inevitably progress to castration-resistant prostate cancer (CRPC), at which stage chemotherapeutics like docetaxel become the first-line treatment. …”
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17320
Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset
Published 2025-02-01“…The values for men gradually decreased after their 20s, and that for women gradually decreased after their 40s, which progressed to a more dramatic decline in the 70s for both sexes. …”
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