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17141
Exploring public perceptions and awareness of Parkinson's disease: A scoping review.
Published 2023-01-01“…It is characterised by both motor and non-motor symptoms including tremor, slow movement, unsteady gait, constipation and urinary incontinence. As the disease progresses, individuals living with the disease are likely to lose their independence and autonomy, subsequently affecting their quality of life. …”
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17142
Empirical Analysis of the Impact of the Internet on Social Trust in Chinese Provinces during 2016-2020
Published 2025-01-01“…This study has significant implications for the scientifically sound and rational utilization of the positive role of the Internet as well as for balancing the development of information technology with social progress. This emphasizes the need to align technological advancement with the broader goals of fostering social trust and promoting social development.…”
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17143
Impact of Comorbidities on Prognosis and Treatment Outcomes in Elderly Patients with Hodgkin Lymphoma
Published 2025-01-01“…., hypertension, diabetes, cardiovascular diseases), to assess their impact on overall survival (OS) and progression-free survival (PFS). Diagnostic efficiency was determined via receiver operating characteristic analysis, while the survival outcomes were evaluated using the Cox proportional hazards model. …”
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17144
Correction of Dysbiosis in Diversion Proctitis: Possibilities of Intraluminal Sanitation and the Prevention of Complications after Reconstructive Surgery
Published 2020-01-01“…Pronounced dysbiotic changes, the progression of catarrhal or erosive diversion colitis and proctosigmoiditis are the risk factors for anastomotic leakage and postoperative bowel dysfunction. …”
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17145
Pharmacotherapy for AMD: state-of-the-art
Published 2019-07-01“…Agents which prevent neovascularization by inhibiting vascular endothelial growth factor (VEGF) are currently used to manage this rapidly progressing type of AMD. It was demonstrated that VEGF inhibiting prevents the development of choroidal neovascular membrane, reduces the sizes of pre-existing membrane, and decreases vascular leakage from new vessels. …”
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17146
Integrated analysis of bioinformatics, mendelian randomization, and experimental validation reveals novel diagnostic and therapeutic targets for osteoarthritis: progesterone as a p...
Published 2025-01-01“…Abstract Background Osteoarthritis (OA), characterized by progressive degeneration of cartilage and reactive proliferation of subchondral bone, stands as a prevalent condition in orthopedic clinics. …”
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17147
HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model
Published 2023-01-01“…Therefore, it is necessary to investigate the new molecules or regulated pathways that can effectively inhibit the progress of sepsis. Objective. NLR family pyrin domain-containing 3 (NLRP3) increased in the procession of sepsis and functioned as the key regulator of pyroptosis. …”
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17148
Concurrent versus sequential immunotherapy with chemoradiotherapy for unresectable stage III non-small-cell lung cancer: a retrospective study
Published 2025-01-01“…Patients were grouped based on concurrent or sequential administration of ICIs with chemoradiotherapy. Median progression-free survival (mPFS), median overall survival (mOS), 1 and 2-year PFS rates, 2 and 3-year OS rates, objective remission rate (ORR), and disease control rate (DCR) were evaluated. …”
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17149
Health recommender systems to facilitate collaborative decision-making in chronic disease management: A scoping review
Published 2025-01-01“…From the thematic analysis, we conclude: (a) the main goal of HRSs is to induce behavior change, but limited research investigates their effectiveness in achieving this aim; (b) studies acknowledge that theories, models, frameworks, and/or guidelines help design HRSs to elicit specific behavior change, but they do not implement them; (c) connections between CDM and HRS purpose should be more explicit; and (d) HRSs can often offer other self-management services, such as progress tracking and chatbots. Conclusions We recommend a greater emphasis on evaluation outcomes beyond algorithmic performance to determine HRS effectiveness and the creation of an evidence-driven, methodological approach to creating HRSs to optimize their use in enhancing patient care. …”
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17150
FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis
Published 2025-02-01“…BackgroundIdiopathic Pulmonary Fibrosis (IPF), an interstitial lung disease of unknown etiology, remains incurable with current therapies, which fail to halt disease progression or restore lung function. However, Feibi Recipe No. 2 (FBR2), a clinically validated traditional Chinese medicine formula, exhibits potential as an IPF treatment.ObjectiveThis study aimed to investigate the regulatory effect of FBR2 on ferroptosis through the SIRT3/p53 pathway and its therapeutic potential in improving IPF.MethodsPulmonary fibrosis was induced in C57BL/6J mice by intratracheal instillation of Bleomycin (BLM), followed by FBR2 treatment via gavage. …”
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17151
« Pas de retour à nos maisons sans satisfaction de nos revendications ». Le Hirak du Rif en actes face au Makhzen
Published 2024-07-01“…Our main argument is that while the movement's activists employed initially (and above all) the most routine tactics of protest (such as demonstrations whose times and locations were publicly announced in advance), they progressively innovated tactically (through, for example, surprise demonstrations known as "chen-ten" and pot-banging protests), moved to new protest sites (such as the various districts of Al Hoceima and the beaches) and encouraged the involvement of heterogeneous protest profiles (many of whom are young and/or have a distant connection to the activist universe) ; these processes fostered the movement's continuity and gave it a disruptive character. …”
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17152
Development of the Big Ten Academic Alliance Collaborative for Women in Medicine and Biomedical Science: “We Built the Airplane While Flying It”
Published 2025-01-01“…These efforts lay a robust foundation for the BTAA CommUNITYten collaborative to foster ongoing collaboration, innovation, and progress in the years to come. Given the importance of steady improvements, this viewpoint may further guide the efforts of other individuals, groups, and leadership supporting women+ as they consider approaches and strategies advocating for gender equity at the national level.…”
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17153
Risk of Dysglycemia in Pregnancy amongst Kenyan Women with HIV Infection: A Nested Case-Control Analysis from the STRiDE Study
Published 2021-01-01“…With the growing awareness of the role HIV plays in the progression of noncommunicable diseases and the disproportionate HIV burden African countries like Kenya face, investigating the potential role HIV plays in increasing dysglycemia amongst pregnant women with HIV is an important area of study. …”
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17154
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17155
Gut Microbiome and Metabolite Characteristics Associated With Different Clinical Stages in Non-Small Cell Lung Cancer Patients
Published 2025-01-01“…Fan Liu,1 Xingbing Lu,2 Mengli Tang,2 Yuzuo Chen,2 Xi Zheng3,4 1Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 3Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 4Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, People’s Republic of ChinaCorrespondence: Xi Zheng, Lung Cancer Center, Department of Thoracic Surgery, West China Hospital, Sichuan University, Guoxue Lane 37, Chengdu, Sichuan Province, People’s Republic of China, Tel +86-28-86298113, Email zhengxi@scu.edu.cnObjective: Our research has pinpointed the gut microbiome’s role in the progression of various pathological types of non-small cell lung cancer (NSCLC). …”
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17156
Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study
Published 2025-01-01“…BackgroundAn increasing number of studies have revealed that gut microbiota influences the development and progression of Colorectal cancer (CRC). However, whether a causal relationship exists between the two remains unclear, and the role of immune cells in this context is not well understood.ObjectiveTo elucidate the causal relationship between gut microbiota and CRC and to explore the potential mediating role of circulating immune cells.Materials and methodsTo analyze the causal relationship between gut microbiota and CRC, we employed a univariable Mendelian randomization (UVMR) approach. …”
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17157
Social and Humanitarian Factor in South Korea's External Relations and The Korean Question
Published 2020-03-01“…Conservative administrations put an emphasis on information pressure on the DPRK while the development of inter-Korean relations was conditioned by the denuclearization of North Korea. Progressive administrations prefer engaging the DPRK in social, humanitarian and economic interactions. …”
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17158
Effectiveness of Virtual Reality Technology Interventions in Improving the Social Skills of Children and Adolescents With Autism: Systematic Review
Published 2025-02-01“…For children and adolescents with LFA, progress was mainly observed in basic skills. Immersive VR interventions are more suitable for the development of complex skills. …”
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17159
CMV Pancreatitis in an Immunocompromised Patient
Published 2021-01-01“…Other more common causes of pancreatitis were ruled out during the progression of this patient, and an elevated lipase with high CMV viral load points towards CMV pancreatitis. …”
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17160
Survival analysis of patients with hepatocellular carcinoma based on the ratio of platelet count to spleen diameter
Published 2025-01-01“…Portal hypertension, the most common outcome of cirrhosis progression, has a high incidence. Platelet count/spleen diameter ratio (PSL) with a cut-off value of 909 can predict the presence of esophagogastric varices and thus portal hypertension, which is also an independent risk factor for early recurrence and late recurrence of hepatocellular carcinoma after resection. …”
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