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16562
Rational pharmacotherapy of primary open-angle glaucoma in elderly and senile patients
Published 2022-11-01“…The main principle of medical management of primary open-angle glaucoma (POAG) is to provide a timely ocular hypotensive therapy directed at lowering intraocular pressure, the only modifiable risk factor in the disease progression, to a target level. The article describes specific approaches to the medical management of elderly and senile patients with POAG, taking into consideration age-related eye problems and medications used for comorbidities. …”
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16563
Effects of a 12-Week Skipping Exercise Program on Leg Endurance in Competitive Badminton Players: A Randomized Controlled Trial
Published 2025-01-01“…The participants in the intervention cohort undertook a 12-week progressive skipping exercise program in conjunction with their regular badminton training, whereas the control group adhered solely to standard training protocols. …”
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16564
EXPERIENCE OF PROJECT-BASED LEARNING: AN ATTEMPT AT OBJECTIVE ANALYSIS OF RESULTS AND PROBLEMS
Published 2018-05-01“…It contributes more to the development of the abilities of more gifted students, but can negatively affect the progress of poorly motivated students. Projects can be realized within the framework of one studied discipline, if its content and structure create conditions for this. …”
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16565
Surgical resection versus thermal ablation after intra-arterial conversion therapy for unresectable hepatocellular carcinoma: a multicenter retrospective one as per the STROBE guid...
Published 2024-12-01“…Cumulative overall survival (OS) and progression-free survival (PFS) were compared using the Kaplan–Meier method with the log-rank test. …”
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16566
MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma
Published 2022-01-01“…Ferroptosis is involved in the progression of various tumors, including the glioblastoma. …”
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16568
« Mon seul Shakespeare »
Published 2013-01-01“…So, some sort of counter-plan is progressively put in place which looks as if it chimed in with the tragic course of events only to better deceive the wild beast named Angelo! …”
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16569
Topographic correlation of microperimetry with foveal microstructure characteristics in idiopathic epiretinal membrane patients with an ectopic inner foveal layer
Published 2025-02-01“…Conclusions The presence of EIFL and decreased VD in the parafoveal region, factors that collectively elevate the risk of disease progression, are significantly and independently correlated with reduced microperimetric retinal sensitivity in patients with idiopathic ERM.…”
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16570
Investigation of sexual life and perceived spousal support in female recipients after kidney transplantation
Published 2025-01-01“…However, recovery in sexual life progresses slowly, and female recipients may need spousal support during this process. …”
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16572
Glycogen Storage Disease Type Ia: A Retrospective Claims Analysis of Complications, Resource Utilization, and Cost of Care
Published 2025-01-01“…**Discussion:** In this large, retrospective database analysis, complications observed among patients with GSDIa were consistent with prior reports and demonstrate the chronic and progressive nature of the disease. Resource utilization was substantial in GSDIa patients, and mean annual total healthcare costs were almost 8 times higher than those of comparators. …”
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16573
Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway
Published 2019-01-01“…Glaucoma is characterized by progressive, irreversible damage to the retinal ganglion cells (RGCs) and their axons. …”
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16574
THE DEVELOPMENT OF SCIENCE AND THE FATE OF A SCIENTIST (FOLLOWING GENETICS)
Published 1997-01-01“…The line becomes almost horizontal and the delta increases with scientific progress. There are rare exceptions, i.e., a highly positioned scientist with a small delta. …”
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16575
The effect of fecal bile acids on the incidence and risk-stratification of colorectal cancer: an updated systematic review and meta-analysis
Published 2025-01-01“…Abstract Recent studies suggest the role of gut microbes in bile acid metabolism in the development and progression of colorectal cancer. However, the surveys of the association between fecal bile acid concentrations and colorectal cancer (CRC) have been inconsistent. …”
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16576
Burden assessment of podoconiosis in Wayu Tuka woreda, east Wollega zone, western Ethiopia: a community-based cross-sectional study
Published 2016-09-01“…Objective Podoconiosis is a neglected tropical disease characterised by a slowly progressive swelling of the foot and lower leg. It is prevalent among subsistence barefoot farmers who live and work in highland areas of the tropics. …”
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16577
Detection method of mixed coin transaction based on CoinJoin——take the Wasabi platform as an example
Published 2023-12-01“…Designed to enhance the privacy of user transactions, mixed coin technology has created disruptions to the address clustering rules typically used for cryptocurrency regulation.Consequently, hackers have begun utilizing mixed coin technology as a tool for money laundering and fund evasion, which has raised concerns among financial regulators regarding the detection of mixed coin transactions.Currently, most detection methods for mixed coin transactions rely on data analysis and statistics, lacking a comprehensive understanding of the internal workings of these transactions.This lack of knowledge may undermine the credibility and effectiveness of detection methods due to the absence of reliable verification data.CoinJoin, a decentralized mixed coin concept, represents one approach, and commercial implementations like Wasabi have gained popularity.Drawing from the characteristics of CoinJoin and its restriction on the size of anonymous transaction sets and mixed coin amounts, a general detection method for CoinJoin mixed coin transactions was devised.Such transactions typically involved multiple inputs and outputs, with more output items than UTXOs in the input, and a high occurrence of duplicate values among the output amounts.A basic detection method for Wasabi was developed by combining the generic detection method for CoinJoin with specific features of Wasabi, as identified in related studies, to complete the detection process.A trusted validation dataset was acquired from the Wasabi platform service interface, and this dataset was analyzed to achieve two objectives.First, the alignment of rule parameters in the Wasabi base detection method was accomplished.Second, a new metric was proposed, measuring the ratio of the highest frequency of duplicate values in the output amount of transactions to the number of UTXOs in the input.This metric assessed the level of user participation in mixed coin transactions, providing a measure of user freedom.Using these two approaches, significant progress is made in the detection of mixed coin transactions.The experiments show that the recall rate of Wasabi’s basic detection method is 94.2% and the accuracy rate is 67.2%.After the analytical feedback from the credible validation dataset, the recall rate of the improved detection method reaches 100% and the accuracy rate is above 99%.The total market size of the entire CoinJoin type of mixed coin transactions was evaluated and predicted based on a common test methodology.It is concluded that the number of CoinJoin mixed coin transactions in today’s mixed coin market represents 1.9 per 1 000 of all Bitcoin transactions and 3.7 per 1 000 of the transaction value at most.…”
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16578
The potential for gene-editing to increase muscle growth in pigs: experiences with editing myostatin
Published 2022-06-01“…However, to date, there has been only limited progress toward models of growth promotion through gene-editing. …”
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16579
Viable Ileosigmoid Knotting, A Very Phenomenon Finding and Rare Cause of Intestinal Obstruction: A Case Report and Literature Review
Published 2025-02-01“…The postoperative course was uneventful.Discussion: Ileosigmoid knotting is a rare, life-threatening cause of intestinal obstruction with rapid progression to intestinal vascular compromise and gangrene. …”
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16580
Cervical cancer screening by cotesting method for Vietnamese women 25–55 years old: a cost-effectiveness analysis
Published 2025-01-01“…The objective is to provide evidence to inform policy and clinical practice in Vietnam.Design Cost-effectiveness analysis using a Markov model with 1 year cycles to simulate the natural progression of CC.Setting The Vietnamese healthcare system, modelled from the provider’s perspective, with parameters adapted to the local context through expert consultations.Participants A simulated cohort of Vietnamese women aged 25–55 years.Interventions The intervention involved cotesting (cytology and HPV testing) three times at 5 year intervals. …”
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