Limited restoration of T cell subset distribution and immune function in older people living with HIV-1 receiving HAART by Na Li, Hong-Yi Zheng, Wei Li, Xiao-Yan He, Mi Zhang, Xia Li, Ren-Rong Tian, Xing-Qi Dong, Zhi-Qiang Shen, Yong-Tang Zheng

“…In addition, we observed a significant association between the CD4 + EM3 subset and the CD8 + EM2 subset with HIV-1 progression, independent of age, suggesting their potential as reliable markers for assessing immune reconstitution in all PLWH. …”
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Identification of Parkinson’s disease using MRI and genetic data from the PPMI cohort: an improved machine learning fusion approach by Yifeng Yang, Liangyun Hu, Yang Chen, Weidong Gu, Guangwu Lin, YuanZhong Xie, Shengdong Nie

“…ObjectiveThis study aim to leverage advanced machine learning techniques to develop and validate novel MRI imaging features and single nucleotide polymorphism (SNP) gene data fusion methodologies to enhance the early identification and diagnosis of Parkinson’s disease (PD).MethodsWe leveraged a comprehensive dataset from the Parkinson’s Progression Markers Initiative (PPMI), which includes high-resolution neuroimaging data, genetic single-nucleotide polymorphism (SNP) profiles, and detailed clinical information from individuals with early-stage PD and healthy controls. …”
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Characterisation of HBV and co-infection with HDV and HIV through spatial transcriptomics by Upkar S Gill, Patrick T F Kennedy, Andrew Hall, Rageshri Dhairyawan, Alberto Quaglia, James M Harris, Colin Nixon, Fadi Issa, Amy Cross, Edward Arbe-Barnes, Jane A McKeating, Dimitra Peppa

“…Transcriptional differences in hepatocyte function suggest disrupted metabolic processes in HDV/HBV co-infection potentially impacting disease progression.Conclusion This proof-of-principle study shows the value of this platform in investigating the complex immune landscape, highlighting relevant host pathways to disease pathogenesis.…”
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Lung function improvement on triple modulators: high-resolution, nationwide data from the Danish Cystic Fibrosis Cohort by Christian Leo-Hansen, Daniel Faurholt-Jepsen, Tavs Qvist, Christine Højte, Bibi U. Nielsen, Thomas Bryrup, Esben H. Henriksen, Terese Katzenstein, Marianne Skov, Inger H.M. Mathiesen, Majbritt Jeppesen, Søren Jensen-Fangel, Hanne V. Olesen, Frederik Fouirnaies Buchvald, Kim Gjerum Nielsen, Espen Jimenez-Solem, Christian Ritz, Tacjana Pressler, Mette F. Olsen, the TransformCF Study Group

“…Close monitoring allowed us to assess the impact of treatment on lung function and progression of lung disease in an unselected nationwide cystic fibrosis population from 6 years of age. …”
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The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review by Li Y, Li C, Fan J, Liu Y, Xu Y, Pang G

“…The mechanisms through which these formulations enhance anti-tumor immunity are multifaceted, involving modulation of immune cell activity, apoptosis induction, and suppression of tumor progression. As cancer immunotherapy evolves, the integration of TCM into conventional treatment regimens may offer enhanced therapeutic efficacy, reduced side effects, and improved overall outcomes for cancer patients. …”
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Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses by Thai-Duong Nguyen, Shristi Khanal, Eunhee Lee, Jinsol Choi, Ganesh Bohara, Nikesh Rimal, Dong-Young Choi, Soyeun Park

“…Thus, our formulation of Lf-ASX-LPs represents a promising strategy for providing neuroprotection and retarding Parkinson’s disease progression. Graphical abstract…”
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Adherence to First-Line Intravesical Bacillus Calmette-Guérin Therapy in the Context of Guideline Recommendations for US Patients With High-Risk Non-muscle Invasive Bladder Cancer by Franklin D. Gaylis, Bruno Emond, Ameur M. Manceur, Anabelle Tardif-Samson, Laura Morrison, Dominic Pilon, Patrick Lefebvre, Lorie A. Ellis, Hiremagalur Balaji, Andrea Ireland

“…**Background:** Bacillus Calmette-Guérin (BCG) can reduce recurrence and delay progression among patients with high-risk non–muscle invasive bladder cancer (NMIBC), but is associated with a substantial emotional, physical, and social burden. …”
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钢桥面板U肋-盖板构造细节（子系统1）疲劳受力行为研究 by 赵秋, 游鹏飞, 杨艳

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Exploring the risk factors of blood transfusion in patients with isolated traumatic brain injury based on machine learning prediction models by LIU Wei, XIONG Ziqing, WU Chenggao, LE Aiping

“…This model may be useful and beneficial for identifying transfusion risks in this population, making clinical transfusion decisions and monitoring progress.…”
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Comparison of h-index and other bibliometrics in Google Scholar and Scopus for articles published by translational science trainees by Laura D. Davis, Corbyn M. Gilmore, Adriana Vargus, Henry Ogbeifun, Yong-Hee P. Chun, Christopher R. Frei

“…Abstract Bibliometrics can help program directors to conduct objective and fair assessments of scholar impact, progress, and collaboration, as well as benchmark performance against peers and programs. …”
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Effects of Sex and Age on Quadriceps and Hamstring Strength and Flexibility in High School Basketball Athletes by Takashi Nagai, Nathaniel Bates, April McPherson, Rena Hale, Timothy Hewett, Nathan D. Schilaty

“…Additionally, those strength and flexibility characteristics are commonly used as clinical tests to monitor progress of athletes with acute or chronic hamstring strains. …”
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Evaluation of Preptin and other Biomarkers in Coronary Artery Disease Patients with and without Diabetes Mellitus by Saja T. Yassen, Layla O. Farhan

“…Conclusion: Preptin may serve as a predictive marker for the progression of declining heart function in people with T2DM. …”
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Assessment of Risk Factors of Chronic Kidney Disease among Patients Attending Medical City Complex by Nabaa Wisam Sabri, Buthaina Ateyah Rashid, Raheem Saber Shwiehk, Azad H. Mahdy

“… Chronic kidney disease is a worldwide health problem that is defined as structural abnormalities or progressive or permanent loss of renal function for 3 months or more, which is usually associated with a decrease in glomerular filtration rate (GFR) of less than 60 mL/min/1.73 m2 or persistent proteinuria, which can lead to end-stage renal disease (ESRD) or kidney failure. …”
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锥形高强中空夹层薄壁钢管混凝土构件的抗弯性能试验研究 by 王先铁, 彭星, 张家平, 闫辰状, 李辛庚, 闫风洁

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高强钢管高强混凝土短柱力学性能智能模型研究 by 刘坚, 彭林苗, 马宏伟, 刘长江, 张专涛, 陈原, 任达, 招渝, 肖海鹏, 杨勤鹏, 戚玉亮, 童华炜

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Using artificial intelligence methods for the optimal synthesis of reversible networks by Taras Kyryliuk, Mykhailo Palahuta, Vitaly Deibuk

“…Considering the relentless progress in the miniaturization of electronic devices and the need to reduce energy consumption, technical challenges in the synthesis of circuit design solutions have become evident. …”
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Biological significance of soluble IL-2 receptor by Calogero Caruso, Giuseppina Candore, Diego Cigna, Antonio Tobia Colucci, Maria Assunta Modica

“…However, since blood sIL-2R levels may correlate with disease progression and/or response to therapy, their measurement may be a useful index of activity and extent of disease. …”
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“Awakened Muse” by Ihor Kalynets in the interartistic dialogue with Oleksa Novakivskyi by Hryhorii Savchuk

“…These conditions are related to historical progress, but above all, to the peculiarities of individual evolution of the author. 2. …”
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Anti-VEGF therapy for proliferative diabetic retinopathy: translating research evidence into clinical practice by E.A. Abdulaeva, E.L. Minkhuzina, A.N. Kuskov

“…&nbsp;Adamyuk Republician Clinical Ophthalmological Hospital, Kazan, Russian </b><b>Federation</b> </p> <p> <i>Diabetic retinopathy (DR) is a common microvascular complication of diabetes. As diabetes progresses, about 50% of patients with severe non-proliferative DR will develop proliferative DR (PDR) within one year. …”
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Evaluation of TNF-α, IL-10 and IL-6 Cytokine Production and Their Correlation with Genotype Variants amongst Tuberculosis Patients and Their Household Contacts. by Lavanya Joshi, Meenakshi Ponnana, Ramya Sivangala, Lakshmi Kiran Chelluri, Prathiba Nallari, Sitaramaraju Penmetsa, Vijayalakshmi Valluri, Sumanlatha Gaddam

“…Evaluation of the cytokines and any of their inherent polymorphisms might provide a useful diagnostic tool in evaluating the immune regulation and the progression of the disease. The cytokines thus released in a paracrine manner in serum may also provide an indirect measure of the cytokine function.…”
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