Shorter Digestion Times of Donor Islets Is Associated With Better Islet Graft Function After Islet Transplantation by Chia-Hao Wang, Christopher Orr, Jeannette Hacker-Stratton, Mohamed El-Shahawy, Keiko Omori, Meirigeng Qi, Fouad Kandeel

“…Thirteen transplants that resulted in progressive decline in patients’ weekly averaged insulin intake over the initial weeks after transplant (assuming constant glucose level) with available 3-month PIR and GFI data were chosen for the investigation. …”
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Effect of long-term transcutaneous auricular vagus nerve stimulation in multiple system atrophy-cerebellar subtype: a case report by Zhao-Di Wang, Zhao-Di Wang, Xiao-Ping Cheng, Zhen-Yi Liu, Di Wu, Jun Ni, Chuan-Juan Chen, Chuan-Juan Chen, Xin-Yuan Chen, Xin-Yuan Chen

“…BackgroundMultiple system atrophy-cerebellar subtype (MSA-C) is a predominance of cerebellar ataxia and autonomic failure. MSA-C has a rapid progression, with average 9 years from symptom onset to death. …”
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Analysis of tumor-infiltrating exhausted T cells highlights IL-6 and PD1 blockade as a combined immunotherapy strategy for non-small cell lung cancer by Lulu Zhang, Lulu Zhang, Xiyuan Guo, Xiyuan Guo, Xiaoke Sun, Jue Liao, Qin Liu, Yingchun Ye, Zhihui Yang, Ratchada Cressey, Qing He, Qing Yuan, Qing Yuan

“…Furthermore, the degree of CD8+ T cell exhaustion exhibited a progressive increase with proximity to the tumor. When CD8+ T cells from peripheral blood and tumor tissues of NSCLC patients were stimulated with IL-6, the expression level of exhaustion markers, especially PD1, was further elevated. …”
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Low-Dose Anti-PD(L)1 for the Treatment of Solid Malignancies by Iza Andrade de A. Souza, Beatriz de M. Dobbert, Barbara G. Sao Jose, Joao Pedro Homse-Netto, Larissa L. Furlan, Maira S. Abreu, Camila Ferrari, Bruno Uchoa, Kathia Abdallah, Stephano N. Lucio, Joao A. Soler, Fabio L.C. Fernandez, Luiza Ferreira, Joao D. Guedes, Aline F. Fares, Daniel V. Araujo

“…Efficacy outcomes, including best clinical overall response rate (cORR), clinical progression-free survival (cPFS), and overall survival (OS), were evaluated.RESULTSFrom January 2020 to May 2023, 71 patients were included: 49 (69%) with LD and 22 (31%) with CD agents. …”
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Atezolizumab plus bevacizumab in patients with unresectable or metastatic mucosal melanoma: 3‐year survival update and multi‐omics analysis by Jie Dai, Tianxiao Xu, Lifeng Li, Meiyu Fang, Jing Lin, Jun Cao, Xue Bai, Caili Li, Xiaoting Wei, Junjie Gu, Yaoyao Liu, Xuan Gao, Xuefeng Xia, Jun Guo, Yu Chen, Lili Mao, Lu Si

“…Patients with upper site melanoma exhibited longer progression‐free survival (PFS), higher tumour neoantigen burden (TNB) and greater copy number variations (CNVs) burden compared to those with lower site melanoma. …”
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Computational identification of anti-cancer compounds targeting the RNA-binding domain of human FOX-1 protein (RBFOX1) by Muhammad Tahir ul Qamar, Pablo Sanz-Jimenez, Shaima Rabeea Banoon, Xi-Tong Zhu, Fahad M. Aldakheel, Nahlah Makki Almansour, Leen A. Aldaiji, Wafa Abdullah I. Al-Megrin, Faisal Ahmad

“…The aforementioned processes are pivotal in cancer progression, making RBFOX1 a significant target for innovative cancer therapies. …”
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Manganese-based immunotherapy synergized with novel supramolecular hydrogel: Advancing localized immune activation strategies in squamous cell carcinoma by Tianqing Wang, Xiaopei Hu, Xin Tian, Ying Wang, Shiyu Zhang, Silu Sun, Ning Ji, Xiaobo Luo, Qianming Chen, Xin Zeng, Hang Zhao, Jing Li

“…Finally, we adopted a range of mouse tumor models to reveal that G-TA-I supramolecular hydrogel drug delivery system loaded with Mn2+ and PD-1 antibody could efficiently activate local immunity, effectively combating the occurrence and progression of HNSCC. These findings indicate that the Mn-αPD-1-loaded in situ sustained-release G-TA-I hydrogel represents a novel, safe, and effective cancer therapeutic drug delivery system that can maximize the efficacy of immunotherapy and reduce the side effects of immunotherapy. …”
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The Russian-Indian Scientific and Technological Cooperation in the First Decade of the 21st Century by Konstantin P. Kurylev, Larisa A. Chereshneva, Mariia N. Starikova, Liudmila A. Belousova

“…They illustrate a diverse array of forms of Russian-Indian cooperation aimed at mutual understanding and progress of both states and peoples. The article is a part of a research project on Soviet-Indian cooperation in the field of science and technology as a resource of the so-called “soft power.” …”
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Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice by Satoshi Okano, Akira Yasui, Shin-ichiro Kanno, Kennichi Satoh, Masahiko Igarashi, Osamu Nakajima

“…Thus, upregulation of KPNA2 seemed to be correlated with progression of the degree of atypia in pancreatic ductal cells. …”
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Subclinical imaging activity in multiple sclerosis patients during war‐related psychological stress by Omri Zveik, Tal Friedman‐Korn, Ariel Rechtman, Tal Ganz, Garrick Hoichman, Lyne Shweiki, Dana Ekstein, Adi Vaknin‐Dembinsky

“…Abstract Objectives Psychological stress has been suggested as a contributory factor in the onset and progression of multiple sclerosis (MS). The 7 October 2023 terrorist attacks in Israel caused significant psychological stress, providing a unique context to study its impact on MS activity. …”
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A Mitochondria‐Related Signature in Diffuse Large B‐Cell Lymphoma: Prognosis, Immune and Therapeutic Features by Zhen‐Zhong Zhou, Jia‐Chen Lu, Song‐Bin Guo, Xiao‐Peng Tian, Hai‐Long Li, Hui Zhou, Wei‐Juan Huang

“…Mitochondria have been demonstrated to be closely involved in tumorigenesis and progression, particularly in DLBCL. Objective The purposes of this study were to identify the prognostic mitochondria‐related genes (MRGs) in DLBCL, and to develop a risk model based on MRGs and machine learning algorithms. …”
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Secondary prevention of preeclampsia by Muhammad Ilham Aldika Akbar, Muhammad Ilham Aldika Akbar, Roudhona Rosaudyn, Khanisyah Erza Gumilar, Khanisyah Erza Gumilar, Renuka Shanmugalingam, Gustaaf Dekker, Gustaaf Dekker

“…Secondary prevention involves pharmacological therapies aimed at stopping the disease’s progression before clinical signs. The predominant approach currently employed is the daily administration of low dose Aspirin and calcium. …”
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Synergistic interaction between wheat streak mosaic virus and Triticum mosaic virus modulates wheat transcriptome to favor disease severity by Haritha Nunna, Nathan A. Palmer, Gautam Sarath, Stephen N. Wegulo, Satyanarayana Tatineni, Satyanarayana Tatineni

“…Synergistic interactions between WSMV and TriMV drastically enhanced disease phenotype compared to individual virus infections. The progression of disease phenotype was correlated to transcriptomic changes, indicating the strong disruption to plant metabolism and likely channeling of energy and metabolites for viral replication. …”
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Research and Design of High Altitude Wind Power Station Operation and Maintenance Auxiliary System by Hang HE, Shaoyong WANG, Jiakang ZHOU, Yuan YANG, Wenjun ZHANG, Kan LIN

“…With the advance in the core control technology, equipment selection and manufacturing technology of high-altitude wind power generation system in the future, the intelligent operation and maintenance technology of high-altitude wind power station can be adapted to the progress, and further promote the rise of high-altitude wind power station.…”
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Low back pain trends attributable to high body mass index over the period 1990–2021 and projections up to 2036 by Jiling Zhang, Baodong Wang, Congying Zou, Tianyi Wang, Lihui Yang, Yu Zhou

“…BackgroundHigh body mass index (BMI) is a crucial determinant in low back pain (LBP) incidence and progression. However, the effect of increased BMI on LBP has been largely overlooked at the global, regional, and national levels. …”
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Artificial Intelligence–Related Dental Research: Bibliometric and Altmetric Analysis by Wei Lu, Xueqian Yu, Yueyang Li, Yi Cao, Yanning Chen, Fang Hua

“…China, the US, South Korea, and Germany had promoted the progress of AI-related dental research. Disease diagnosis, orthodontic applications, and morphology segmentation were current hotspots. …”
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HGF-Modified Dental Pulp Stem Cells Mitigate the Inflammatory and Fibrotic Responses in Paraquat-Induced Acute Respiratory Distress Syndrome by Panpan Geng, Yuning Zhang, Huan Zhang, Xiwen Dong, Yuefeng Yang, XiaoNa Zhu, Chu-Tse Wu, Hua Wang

“…Paraquat (PQ) poisoning can cause acute lung injury and progress to pulmonary fibrosis and eventually death without effective therapy. …”
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Modelo CFD con validación de campo para el estudio de los alcances de efectividad de técnicas de mitigación de radón por despresurización = CFD model with field validation for the... by Isabel Sicilia, Borja Frutos, Carmen Alonso, Fernando Martín-Consuegra, Fernando de-Frutos, Ignacio Oteiza, Carlos Sainz, Luis S. Quindós

“…The paper presents the progress in the development of a simulation model in COMSOL Multiphysics for the study of radon gas movements under screed. …”
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Impaired ARID1A expression attenuated the immune response in gastric cancer via histone acetylation by Yu Tang, Ruizhi Zhang, Gan Mao, Chong Li, Yisong Gao, Xuebing Zhou, Wenxiang Nie, Tianyu Song, Suao Liu, Kaixiong Tao, Peng Zhang, Wei Li

“…Notably, the application of deacetylase inhibitors effectively reversed the effects of ARID1A depletion on tumor progression and significantly enhanced the efficacy of immunotherapy. …”
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Prognostic Nutritional Index Predicts Early Mortality in Diffuse Large B-cell Lymphoma by Erman OZTURK, Tayfun ELIBOL, Emrah KILICASLAN, Beyza KABAYUKA, Işıl ERDOGAN OZUNAL

“…Pre-treatment IPI, R-IPI, and PNI scores and progression-free survival (PFS) and overall survival (OS) times were calculated. …”
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