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15821
Analysis of the body composition of rats with experimental diabetes mellitus type 1 and its correction
Published 2024-12-01“…Two-week correction of diabetes with L-arginine and N-acetyl-L-cysteine at 8th week significantly reduces glucose concentration in subgroups, but does not affect the progressive reduction of body weight, fat and free-fat mass, and fluid volumes. …”
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15822
Ameliorative Impact of Liraglutide on Chronic Intermittent Hypoxia-Induced Atrial Remodeling
Published 2022-01-01“…Previous evidence proved that atrial anatomical remodeling (AAR) and atrial electrical remodeling (AER) are crucial for the progression and maintenance of AF. This study is aimed at investigating the impact of the glucagon-like peptide-1 (GLP-1) receptor agonist, Liraglutide (Lir), on atrial remodeling (AR) mouse model induced by chronic intermittent hypoxia (CIH). …”
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15823
The predictive role of tertiary lymphoid structures in the prognosis and response to immunotherapy of lung cancer patients: a systematic review and meta-analysis
Published 2025-01-01“…The hazard ratio (HR) and corresponding 95% confidence interval (CI) for overall survival (OS), disease-free survival (DFS), recurrence-free survival (RFS), progression-free survival (PFS) and disease-specific survival (DSS) were extracted and merged with STATA 14.0. …”
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15824
Hypergammaglobulinemia in Hidradenitis Suppurativa Patients: A New Emerging Association
Published 2025-01-01“…If validated, hypergammaglobulinemia could be used to monitor disease progression and customize treatments. In conclusion, integrating immunological assessments into HS management could improve patient outcomes, particularly in younger demographics. …”
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15825
Development and application of health-preserving training methods for ball exercises for young gymnasts aged 8-9
Published 2024-06-01“…The analysis of the results showed that the proposed methodologies significantly improve the performance of complex elements, such as rolls and ball throws. Progress in performing these elements with the left hand was especially notable. …”
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15826
Evidence for Decreased Nucleolar PARP-1 as an Early Marker of Cognitive Impairment
Published 2019-01-01“…Our data suggest that disruption of nucleolar form and function is an early and important step in the progression of cognitive impairment.…”
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15827
Biology, genetics, and ecology of the cosmopolitan ectomycorrhizal ascomycete Cenococcum geophilum
Published 2025-01-01“…The capacity of this symbiont to rapidly colonize disturbed or newly formed environments promotes the development of conditions that support the growth of other plant species, thus playing a crucial role in the ecological progression and restoration of ecosystems. Several C. geophilum isolates are known to enhance the drought resistance of host plants, a trait that is becoming increasingly important in the context of climate change and frequent drought events. …”
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15828
From fossil fuels to alternative fuels: strategy development for a sustainable transport sector in Germany
Published 2025-01-01“…Although Germany has made substantial progress in reducing emissions across various sectors, the transport sector remains a notable exception, showing little improvement. …”
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What are the general public’s expectations about the likely duration of common acute infections? A cross-sectional survey of Australian residents
Published 2024-12-01“…Most common reasons for care-seeking were severe or worsening symptoms, a desire for quick recovery and fear of progression to complications. After being shown typical durations, the proportion of participants who reported having no concerns waiting for spontaneous resolution while managing symptoms with over-the-counter medications ranged across the infections and was highest for common cold (68%) and lowest for UTI (31%).Conclusion Participants underestimated the duration of some infections compared with evidence-based estimates and were accurate in their estimates for other infections. …”
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15831
Genesis of feudalism in Western Europe and its influence to the globai process of history: The conceptions of L. Vasilyev and E. Gudavičius
Published 2004-12-01“…Gudavičius stresses that feudalism created an individual producer (peasant) farm and consequently it was an essential progress in the social development of the societies of Western Europe. …”
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15835
Features of Crohn's Disease Depending on the Age of Disease Onset
Published 2023-12-01“…Not only pediatric onset, but also the onset of Crohn's disease before the age of 40 is a risk factor for the progression of the disease and its more severe course.…”
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15836
Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma
Published 2025-01-01“…Circulating miRNAs (miRs) are important regulators of cancer progression and are potentially useful for GBM diagnosis and treatment. …”
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15837
Invited perspectives: Integrating hydrologic information into the next generation of landslide early warning systems
Published 2025-01-01“…Given the increasing number of studies across the globe using hydrologic monitoring, mathematical modeling, or both in combination, it is now possible to make some insights into the advantages versus limitations of this approach. The extensive progress demonstrates the value of in situ hydrologic information for reducing both failed and false alarms through the ability to characterize infiltration during – as well as the drainage and drying processes between – major storm events. …”
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15839
PEDF Overexpression Ameliorates Cardiac Lipotoxicity in Diabetic Cardiomyopathy via Regulation of Energy Metabolism
Published 2025-01-01“…Tuohua Mao, Ye Wang Department of Endocrinology, Renmin Hospital of Wuhan University, Wuhan, 430060, People’s Republic of ChinaCorrespondence: Ye Wang, Department of Endocrinology, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuchang, Wuhan, Hubei, 430060, People’s Republic of China, Email wye2018@whu.edu.cnBackground: Early alterations in cardiac energy metabolism and lipotoxicity are crucial factors in the pathogenesis and progression of diabetic cardiomyopathy (DCM). The excessive accumulation of lipid metabolic intermediates within the myocardium can lead to increased production of reactive oxygen species (ROS) and promote apoptosis. …”
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15840
Programmed cell death 1 inhibitor alone or combined with chemotherapy for patients with locally advanced or metastatic urothelial carcinoma: a single-center experience
Published 2024-12-01“…Kaplan–Meier curves were used to assess progression-free survival (PFS) and OS. A Cox regression analysis was conducted to explore the association of baseline variables with OS. …”
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